Industrial Applications of Liquid Chromatography Time-of-Flight Mass Spectrometry

Liquid Chromatography Time-of-Flight Mass Spectrometry: Principles, Tools, and Applications for Accurate Mass Analysis

Volumn 173, Issue , 2008, Pages 151-172

  Gilbert, Jeffrey R ^a   Balcer, Jesse L ^a   Young, Scott A ^a   Markham, Dan A ^a   Duebelbeis, Dennis O ^a   Lewer, Paul ^a  

^a DOW AGROSCIENCES LLC   (United States)

Author keywords

Applications of LC TOFMS in toxicology; Industrial applications of liquid chromatography; Natural products discovery dereplication and identification

Indexed keywords

MASS SPECTROMETRY;

DEREPLICATION; LIQUID CHROMATOGRAPHY TIME-OF-FLIGHT MASS SPECTROMETRIES;

LIQUID CHROMATOGRAPHY;

EID: 84948975799     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470429969.ch10     Document Type: Chapter

References (30)

1. Balogh, M.P., The commercialization of LC-MS during 1987-1997: A review of ten successful years, LC-GC, 1998, 16 (2), 135-136, 138, 140, 142, 144.
2. Niessen, W.M.A., Advances in instrumentation in liquid chromatography-mass spectrometry and related liquid-introduction techniques, J Chromatogr A, 1998, 794, 407-435.
3. Morris, H.R.; Paxton, T.; Dell, A.; Langhorne, J.; Berg, M.; Bordoli, R.S.; Hoyes, J.; Bateman, R. H., High sensitivity collisionally-activated decomposition tandem mass spectrometry on a novel quadrupole/orthogonal-acceleration time-of-flight mass spectrometer, Rapid Commun Mass Spectrom, 1996, 10, 889-896.
4. Shevchenko, A.; Chernushevich, I.; Ens, W.; Standing, K.G.; Thomson, B.; Wilm, M.; Mann, M., Rapid " de novo " peptide sequencing by a combination of nanoelectrospray, isotopic labeling and a quadrupole/time-of-flight mass spectrometer, Rapid Commun Mass Spectrom, 1997, 11, 1015-1024.
5. Eckers, C.; Haskins, N.; Langridge, J., The use of liquid chromatography combined with a quadrupole time-of-flight analyzer for the identification of trace impurities in drug substance, Rapid Commun Mass Spectrom, 1997, 11, 1916-1922.
6. Eckers, C.; Wolff, J.-C.; Haskins, N.J.; Sage, A.B.; Giles, K.; Bateman, R., Accurate mass liquid chromatography/mass spectrometry on orthogonal acceleration time-of-flight mass analyzers using switching between separate sample and reference sprays. 1. Proof of concept, Anal. Chem., 2000, 72, 3683-3688.
7. Wolff, J.-C.; Eckers, C.; Sage, A.B.; Giles, K.; Bateman, R., Accurate mass liquid chromatography/mass spectrometry on quadrupole orthogonal acceleration time-of-flight mass analyzers using switching between separate sample and reference sprays. 2. Applications using the dual-electrospray ion source, Anal. Chem., 2001, 73, 2605-2612.
8. Fjeldsted, J., Time-of-Flight Mass Spectrometry, Agilent Technologies Technical Overview #59890-0373EN.
9. McIntyre, D., Advantages of Wide Dynamic Range on an Orthogonal Acceleration Time-of-Flight Mass Spectrometer, Agilent Technologies Technical Overview #5989-1728EN.
10. Ferrer, I.; Thurman, E.M.; Garcia-Reyes, J.F.; Fernandez-Alba, A., Identification and quantitation of pesticides in vegetables by liquid chromatography time-of-flight mass spectrometry, Trends Anal. Chem., 2005, 24, 671-682.
11. Thurman, E.M.; Ferrer, I.; Zweigenbaum, J.A., High-resolution and accurate mass analysis of xenobiotics in food. Anal. Chem., 2006, 78, 6702-6708.
12. Constant, H.L.; Beecher, C.W., A method for the dereplication of natural product extracts using electrospray HPLC/MS, Nat Prod Lett, 1995, 6, 193-196.
13. Kebarle, P.; Tang, L., From ions in solution to ions in the gas phase-the mechanism of electrospray mass spectrometry, Anal Chem, 1993, 65, 972 A-986 A.
14. Gilbert, J.R.; Lewer, P.; Carr, A.W.; Snipes, C.E.; Balcer, J.L., Gerwick, W., Natural product dereplication and structural elucidation using LC/MSn combined with accurate mass LC/MS and LC/MS/MS, Proceedings of the 47th ASMS Conference on Mass Spectrometry and Allied Topics, Dallas, Texas, June 13-17, 1999.
15. Potterat, O.; Wagner, K.; Haag, H., Liquid chromatography-electrospray time-of-flight mass spectrometry for on-line accurate mass determination and identification of cyclodepsipeptides in a crude extract of the fungus metarrhizium anisopliae, J Chromatogr A, 2000, 872, 85-90.
16. Dictionary of Natural Products on DVD; 2007; Chapman and Hall/CRC.
17. Gilbert, J.R.; Lewer, P.; Duebelbeis, D.O.; Carr, A.W.; Snipes, C.E.; Williamson, R.T., Identification of biologically-active compounds from nature using LC-MS in Mass Spectrometry, LC/MS/MS and TOF/MS: Analysis of Emerging Contaminants, ACS Symposium vol. 80, Imma Ferrer and E.M. Thurman, Eds., Oxford University Press and the American Chemical Society (2003).
18. Marfey, P., Determination of D-amino acids. II. Use of a bifunctional reagent, 1,5-difluoro-2,4-dinitrobenzene, Carlsberg Res. Commun., 1984, 49, 591-596.
19. Nielsen, K.F.; Smedsgaard, J., Fungal metabolite screening: database of 474 mycotoxins and fungal metabolites for dereplication by standardized liquid chromatography-UV-mass spectrometry methodology, J Chromatogr A, 2003, 1002, 111-136.
20. Balcer, J.L; Gilbert, J.R.; Linder, S.J.; Magnussen, J.D.; Johnson, P.J.; Krieger, M., Identification of novel plant metabolites using accurate mass, MS/MS data, nanospray technology, and unique isotope pattern recognition, Proceedings of the 55th ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, IN, June 3-7, 2006.
21. Hager, J. W., A new linear ion trap mass spectrometer, Rapid Commun. Mass Spectrom., 2002, 16, 512-526.
22. Tornqvist, M.; Mowrer, J.; Jensen, S.; Ehrenberg, L., Monitoring of environmental cancer initiators through hemoglobin adducts by a modified Edman degradation method., Anal. Biochem, 1986, 154, 255-266.
23. Gilar, M.; Olivova, P.; Daly, E.; Gebler, J.C., Orthogonality of Separation in Two-Dimensional Liquid Chromatography, Anal. Chem., 2005, 77, 6426-6434.
24. Kajdan, T.; Cortes, H.; Kuppannan, K.; Young, S.A., Development of a comprehensive multidimensional liquid chromatography system with tandem mass spectrometry detection for detailed characterization of recombinant proteins, J Chromatogr A, 2008, 1189, 183-195.
25. Karnoup, A.S.; Kuppannan, K.; Young, S.A., A novel HPLC-UV-MS method for quantitative analysis of protein glycosylation, J Chromatogr B, 2007, 859, 178-191.
26. Mazzeo, J.; Wheat, T.; Gllece-Castro, B.; Lu, Z., Next generation peptide mapping with ultra performance liquid chromatography, BioPharm. International, 2006, 19, 22-23.
27. Yang, X.; Ma, L.; Carr, P.W., High temperature fast chromatography of proteins using a silica-based stationary phase with greatly enhanced low pH stability, J. Chromatogr A, 2005, 1079, 213-220.
28. Dillon, T.M.; Bondarenko, P.V.; Rehder, D.S.; Pipes, G.D.; Kleemann, G.R.; Ricci, M.S., Optimization of a reversed-phase high-performance liquid chromatography/mass spectrometry method for characterizing recombinant antibody heterogeneity and stability, J. Chromatogr A, 2006, 1120, 112-120.
29. Selttineri, C.A.; BurlIngame, A.L. In Z. El Rassi (Editor), Carbohydrate Analysis: High Performance Liquid Chromatography and Capillary Electrophoresis. Elsevier, Amsterdam, 1995, p. 447.
30. Kirkpatrick, D.S.; Gerber, S.A.; Gygi, S.P., The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications, Methods, 2005, 35, 265-273.