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Volumn 56, Issue 12, 2015, Pages 2381-2392

Statin action favors normalization of the plasma lipidome in the atherogenic mixed dyslipidemia of MetS: Potential relevance to statin-associated dysglycemia

Author keywords

Cholesterol ; Lipidomics ; Metabolic syndrome; Obesity ; Omega 3 fatty acids ; Pitavastatin ; Plasmalogens

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPIDOME; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PITAVASTATIN; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL; CHOLESTEROL; LIPOPROTEIN;

EID: 84948971422     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.P061143     Document Type: Article
Times cited : (44)

References (42)
  • 1
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: A metaanalysis of data from 170,000 participants in 26 randomised trials
    • Baigent , C. , L. Blackwell , J. Emberson , L. E. Holland , C. Reith , N. Bhala , R. Peto , E. H. Barnes , A. Keech , J. Simes , et al . 2010 . Efficacy and safety of more intensive lowering of LDL cholesterol: a metaanalysis of data from 170,000 participants in 26 randomised trials. Lancet . 376 : 1670 - 1681 .
    • (2010) Lancet , vol.376 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3    Holland, L.E.4    Reith, C.5    Bhala, N.6    Peto, R.7    Barnes, E.H.8    Keech, A.9    Simes, J.10
  • 3
    • 0036790614 scopus 로고    scopus 로고
    • Statin therapy in acute coronary syndromes: Mechanistic insight into clinical benefit
    • Sposito , A. C. , and M. J. Chapman . 2002 . Statin therapy in acute coronary syndromes: mechanistic insight into clinical benefit. Arterioscler. Thromb. Vasc. Biol. 22 : 1524 - 1534 .
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 1524-1534
    • Sposito, A.C.1    Chapman, M.J.2
  • 4
    • 33845876333 scopus 로고    scopus 로고
    • Risks associated with statin therapy: A systematic overview of randomized clinical trials
    • Kashani , A. , C. O. Phillips , J. M. Foody , Y. Wang , S. Mangalmurti , D. T. Ko , and H. M. Krumholz . 2006 . Risks associated with statin therapy: a systematic overview of randomized clinical trials. Circulation . 114 : 2788 - 2797 .
    • (2006) Circulation , vol.114 , pp. 2788-2797
    • Kashani, A.1    Phillips, C.O.2    Foody, J.M.3    Wang, Y.4    Mangalmurti, S.5    Ko D, T.6    Krumholz, H.M.7
  • 5
    • 84864861863 scopus 로고    scopus 로고
    • Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: An analysis from the JUPITER trial
    • Ridker , P. M. , A. Pradhan , J. G. MacFadyen , P. Libby , and R. J. Glynn . 2012 . Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial. Lancet . 380 : 565 - 571 .
    • (2012) Lancet , vol.380 , pp. 565-571
    • Ridker, P.M.1    Pradhan, A.2    MacFadyen, J.G.3    Libby, P.4    Glynn, R.J.5
  • 6
    • 84871921229 scopus 로고    scopus 로고
    • Cardiovascular event reduction versus new-onset diabetes during atorvastatin therapy: Effect of baseline risk factors for diabetes
    • Waters , D. D. , J. E. Ho , S. M. Boekholdt , D. A. DeMicco , J. J. Kastelein , M. Messig , A. Breazna , and T. R. Pedersen . 2013 . Cardiovascular event reduction versus new-onset diabetes during atorvastatin therapy: effect of baseline risk factors for diabetes. J. Am. Coll. Cardiol. 61 : 148 - 152 .
    • (2013) J. Am. Coll. Cardiol. , vol.61 , pp. 148-152
    • Waters, D.D.1    Ho J, E.2    Boekholdt, S.M.3    DeMicco, D.A.4    Kastelein, J.J.5    Messig, M.6    Breazna, A.7    Pedersen, T.R.8
  • 7
    • 21644456797 scopus 로고    scopus 로고
    • The IDF consensus worldwide definition of the metabolic sybdrome
    • Accessed October 2015
    • Alberti , G. , P. Zimmet , J. Shaw , and S. M. Grundy . 2006 . The IDF consensus worldwide definition of the metabolic sybdrome. IDF Communications. Accessed October 31, 2015 at http://www.idf.org/ webdata/docs/IDF-Meta-def-final.pdf.
    • (2006) IDF Communications , vol.31
    • Alberti, G.1    Zimmet, P.2    Shaw, J.3    Grundy, S.M.4
  • 8
    • 79958148945 scopus 로고    scopus 로고
    • Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: Evidence and guidance for management
    • Chapman , M. J. , H. N. Ginsberg , P. Amarenco , F. Andreotti , J. Boren , A. L. Catapano , O. S. Descamps , E. Fisher , P. T. Kovanen , J. A. Kuivenhoven , et al . 2011 . Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur. Heart J. 32 : 1345 - 1361 .
    • (2011) Eur. Heart J. , vol.32 , pp. 1345-1361
    • Chapman, M.J.1    Ginsberg, H.N.2    Amarenco, P.3    Andreotti, F.4    Boren, J.5    Catapano, A.L.6    Descamps, O.S.7    Fisher, E.8    Kovanen, P.T.9    Kuivenhoven, J.A.10
  • 9
    • 84893818936 scopus 로고    scopus 로고
    • HofkerAre hypertriglyceridemia and low HDL causal factors in the development of insulin resistance?
    • Li , N. , J. Fu , D. P. Koonen , J. A. Kuivenhoven , H. Snieder , and M. H. Hofker . 2014 . Are hypertriglyceridemia and low HDL causal factors in the development of insulin resistance? Atherosclerosis . 233 : 130 - 138 .
    • (2014) Atherosclerosis , vol.233 , pp. 130-138
    • Li, N.1    Fu, J.2    Koonen, D.P.3    Kuivenhoven, J.A.4    Snieder, H.5    Hofker, M.H.6
  • 10
    • 84939969799 scopus 로고    scopus 로고
    • Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: A 6 year follow-up study of the METSIM cohort
    • Cederberg , H. , A. Stancakova , N. Yaluri , S. Modi , J. Kuusisto , and M. Laakso . 2015 . Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort. Diabetologia . 58 : 1109 - 1117 .
    • (2015) Diabetologia , vol.58 , pp. 1109-1117
    • Cederberg, H.1    Stancakova, A.2    Yaluri, N.3    Modi, S.4    Kuusisto, J.5    Laakso, M.6
  • 12
    • 84884474355 scopus 로고    scopus 로고
    • Comparative tolerability and harms of individual statins: A study-level network meta-analysis of 246,955 participants from 135 randomized, controlled trials
    • Naci , H. , J. Brugts , and T. Ades . 2013 . Comparative tolerability and harms of individual statins: a study-level network meta-analysis of 246,955 participants from 135 randomized, controlled trials. Circ. Cardiovasc. Qual. Outcomes . 6 : 390 - 399 .
    • (2013) Circ. Cardiovasc. Qual. Outcomes , vol.6 , pp. 390-399
    • Naci, H.1    Brugts, J.2    Ades, T.3
  • 15
    • 84936817948 scopus 로고    scopus 로고
    • Effect of pitavastatin on glucose, HbA1c and incident diabetes: A meta-analysis of randomized controlled clinical trials in individuals without diabetes
    • Vallejo-Vaz , A. J. , S. R. Kondapally Seshasai , K. Kurogi , I. Michishita , T. Nozue , S. Sugiyama , S. Tsimikas , H. Yoshida , and K. K. Ray . 2015 . Effect of pitavastatin on glucose, HbA1c and incident diabetes: a meta-analysis of randomized controlled clinical trials in individuals without diabetes. Atherosclerosis . 241 : 409 - 418 .
    • (2015) Atherosclerosis , vol.241 , pp. 409-418
    • Vallejo-Vaz, A.J.1    Kondapally Seshasai, S.R.2    Kurogi, K.3    Michishita, I.4    Nozue, T.5    Sugiyama, S.6    Tsimikas, S.7    Yoshida, H.8    Ray, K.K.9
  • 16
    • 74549148035 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein: At the heart of the action of lipidmodulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors
    • Chapman , M. J. , W. Le Goff , M. Guerin , and A. Kontush . 2010 . Cholesteryl ester transfer protein: at the heart of the action of lipidmodulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors. Eur. Heart J. 31 : 149 - 164 .
    • (2010) Eur. Heart J. , vol.31 , pp. 149-164
    • Chapman, M.J.1    Goff, W.L.2    Guerin, M.3    Kontush, A.4
  • 18
    • 84883732971 scopus 로고    scopus 로고
    • Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: Impact on small HDL particles
    • Ståhlman , M. , B. Fagerberg , M. Adiels , K. Ekroos , J. M. Chapman , A. Kontush , and J. Boren . 2013 . Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: impact on small HDL particles. Biochim. Biophys. Acta . 1831 : 1609 - 1617 .
    • (2013) Biochim. Biophys. Acta. , vol.1831 , pp. 1609-1617
    • Ståhlman, M.1    Fagerberg, B.2    Adiels, M.3    Ekroos, K.4    Chapman, J.M.5    Kontush, A.6    Boren, J.7
  • 19
  • 21
    • 84898891503 scopus 로고    scopus 로고
    • Lipidomics: Potential role in risk prediction and therapeutic monitoring for diabetes and cardiovascular disease
    • Meikle , P. J. , G. Wong , C. K. Barlow , and B. A. Kingwell . 2014 . Lipidomics: potential role in risk prediction and therapeutic monitoring for diabetes and cardiovascular disease. Pharmacol. Ther. 143 : 12 - 23 .
    • (2014) Pharmacol. Ther , vol.143 , pp. 12-23
    • Meikle, P.J.1    Wong, G.2    Barlow, C.K.3    Kingwel, B.A.4
  • 23
    • 84899092930 scopus 로고    scopus 로고
    • Effect of high-dose pitavastatin on glucose homeostasis in patients at elevated risk of new-onset diabetes: Insights from the CAPITAIN and PREVAIL-US studies
    • Chapman , M. J. , A. Orsoni , P. Robillard , N. Hounslow , C. A. Sponseller , and P. Giral . 2014 . Effect of high-dose pitavastatin on glucose homeostasis in patients at elevated risk of new-onset diabetes: insights from the CAPITAIN and PREVAIL-US studies. Curr. Med. Res. Opin. 30 : 775 - 784 .
    • (2014) Curr. Med. Res. Opin. , vol.30 , pp. 775-784
    • Chapman, M.J.1    Orsoni, A.2    Robillard, P.3    Hounslow, N.4    Sponseller, C.A.5    Giral, P.6
  • 24
    • 0141885327 scopus 로고    scopus 로고
    • Small, dense HDL particles exert potent protection of atherogenic LDL against oxidative stress
    • Kontush , A. , S. Chantepie , and M. J. Chapman . 2003 . Small, dense HDL particles exert potent protection of atherogenic LDL against oxidative stress. Arterioscler. Thromb. Vasc. Biol. 23 : 1881 - 1888 .
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 1881-1888
    • Kontush, A.1    Chantepie, S.2    Chapman, M.J.3
  • 25
    • 73849121438 scopus 로고    scopus 로고
    • HDL3-mediated inactivation of LDL-associated phospholipid hydroperoxides is determined by the redox status of apolipoprotein A-I and HDL particle surface lipid rigidity: Relevance to inflammation and atherogenesis
    • Zerrad-Saadi , A. , P. Therond , S. Chantepie , M. Couturier , K. A. Rye , M. J. Chapman , and A. Kontush . 2009 . HDL3-mediated inactivation of LDL-associated phospholipid hydroperoxides is determined by the redox status of apolipoprotein A-I and HDL particle surface lipid rigidity: relevance to inflammation and atherogenesis. Arterioscler. Thromb. Vasc. Biol. 29 : 2169 - 2175 .
    • (2009) Arterioscler. Thromb.Vasc. Biol. , vol.29 , pp. 2169-2175
    • Zerrad-Saadi, A.1    Therond, P.2    Chantepie, S.3    Couturier, M.4    Rye, K.A.5    Chapman, M.J.6    Kontush, A.7
  • 29
    • 6344267152 scopus 로고    scopus 로고
    • Metabolic syndrome is associated with elevated oxidative stress and dysfunctional dense high-density lipoprotein particles displaying impaired antioxidative activity
    • Hansel , B. , P. Giral , E. Nobecourt , S. Chantepie , E. Bruckert , M. J. Chapman , and A. Kontush . 2004 . Metabolic syndrome is associated with elevated oxidative stress and dysfunctional dense high-density lipoprotein particles displaying impaired antioxidative activity. J. Clin. Endocrinol. Metab. 89 : 4963 - 4971 .
    • (2004) J. Clin.Endocrinol. Metab. , vol.89 , pp. 4963-4971
    • Hansel, B.1    Giral, P.2    Nobecourt, E.3    Chantepie, S.4    Bruckert, E.5    Chapman, M.J.6    Kontush, A.7
  • 30
    • 84886742013 scopus 로고    scopus 로고
    • Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: Effect of gender and age: EPIRCE cross-sectional study
    • Gayoso-Diz , P. , A. Otero-Gonzalez , M. X. Rodriguez-Alvarez , F. Gude , F. Garcia , A. De Francisco , and A. G. Quintela . 2013 . Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study. BMC Endocr. Disord. 13 : 47 .
    • (2013) BMC Endocr. Disord. , vol.13 , pp. 47
    • Gayoso-Diz, P.1    Otero-Gonzalez, A.2    Rodriguez-Alvarez, M.X.3    Gude, F.4    Garcia, F.5    Francisco, A.D.6    Quintela, A.G.7
  • 31
    • 77952686086 scopus 로고    scopus 로고
    • Effect of statins on HDL-C: A complex process unrelated to changes in LDL-C: Analysis of the VOYAGER database
    • Barter , P. J. , G. Brandrup-Wognsen , M. K. Palmer , and S. J. Nicholls . 2010 . Effect of statins on HDL-C: a complex process unrelated to changes in LDL-C: analysis of the VOYAGER database. J. Lipid Res. 51 : 1546 - 1553 .
    • (2010) J. Lipid Res. , vol.51 , pp. 1546-1553
    • Barter, P.J.1    Brandrup-Wognsen, G.2    Palmer, M.K.3    Nicholls, S.J.4
  • 32
    • 33646749287 scopus 로고    scopus 로고
    • Plasma sphingomyelin and subclinical atherosclerosis: Findings from the multi-ethnic study of atherosclerosis
    • Nelson , J. C. , X. C. Jiang , I. Tabas , A. Tall , and S. Shea . 2006 . Plasma sphingomyelin and subclinical atherosclerosis: findings from the multi-ethnic study of atherosclerosis. Am. J. Epidemiol. 163 : 903 - 912 .
    • (2006) Am. J.Epidemiol. , vol.163 , pp. 903-912
    • Nelson, J.C.1    Jiang, X.C.2    Tabas, I.3    Tall, A.4    Shea, S.5
  • 33
    • 0031442545 scopus 로고    scopus 로고
    • HDL phospholipid content and composition as a major factor determining cholesterol efflux capacity from Fu5AH cells to human serum
    • Fournier , N. , J. L. Paul , V. Atger , A. Cogny , T. Soni , M. de la Llera- Moya , G. Rothblat , and N. Moatti . 1997 . HDL phospholipid content and composition as a major factor determining cholesterol efflux capacity from Fu5AH cells to human serum. Arterioscler. Thromb. Vasc. Biol. 17 : 2685 - 2691 .
    • (1997) Arterioscler. Thromb.Vasc. Biol. , vol.17 , pp. 2685-2691
    • Fournier, N.1    Paul, J.L.2    Atger, V.3    Cogny, A.4    Soni, T.5    Moya, M.D.L.L.6    Rothblat, G.7    Moatti, N.8
  • 34
    • 34547635393 scopus 로고    scopus 로고
    • Preferential sphingosine-1-phosphate enrichment and sphingomyelin depletion are key features of small dense HDL3 particles: Relevance to antiapoptotic and antioxidative activities
    • Kontush , A. , P. Therond , A. Zerrad , M. Couturier , A. Negre- Salvayre , J. A. de Souza , S. Chantepie , and M. J. Chapman . 2007 . Preferential sphingosine-1-phosphate enrichment and sphingomyelin depletion are key features of small dense HDL3 particles: relevance to antiapoptotic and antioxidative activities. Arterioscler. Thromb. Vasc. Biol. 27 : 1843 - 1849 .
    • (2007) Arterioscler. Thromb. Vasc. Biol. , vol.27 , pp. 1843-1849
    • Kontush, A.1    Therond, P.2    Zerrad, A.3    Couturier, M.4    Salvayre, A.N.5    Souza, J.A.D.6    Chantepie, S.7    Chapman, M.J.8
  • 37
    • 0029148689 scopus 로고
    • Delay of copper-catalyzed oxidation of low density lipoprotein by in vitro enrichment with choline or ethanolamine plasmalogens
    • Jürgens , G. , A. Fell , G. Ledinski , Q. Chen , and F. Paltauf . 1995 . Delay of copper-catalyzed oxidation of low density lipoprotein by in vitro enrichment with choline or ethanolamine plasmalogens. Chem. Phys. Lipids . 77 : 25 - 31 .
    • (1995) Chem. Phys. Lipids. , vol.77 , pp. 25-31
    • Jürgens, G.1    Fell, A.2    Ledinski, G.3    Chen, Q.4    Paltauf, F.5
  • 40
    • 78751502294 scopus 로고    scopus 로고
    • Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo
    • Pynn , C. J. , N. G. Henderson , H. Clark , G. Koster , W. Bernhard , and A. D. Postle . 2011 . Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo. J. Lipid Res. 52 : 399 - 407 .
    • (2011) J. Lipid Res. , vol.52 , pp. 399-407
    • Pynn, C.J.1    Henderson, N.G.2    Clark, H.3    Koster, G.4    Bernhard, W.5    Postle, A.D.6
  • 41
    • 84873199254 scopus 로고    scopus 로고
    • Physiological roles of phosphatidylethanolamine N-methyltransferase
    • Vance , D. E. 2013 . Physiological roles of phosphatidylethanolamine N-methyltransferase. Biochim. Biophys. Acta . 1831 : 626 - 632 .
    • (2013) Biochim. Biophys.Acta. , vol.1831 , pp. 626-632
    • Vance, D.E.1
  • 42
    • 79960539641 scopus 로고    scopus 로고
    • ESC/EAS Guidelines for the management of dyslipidaemias: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
    • Reiner , Z. , A. L. Catapano , G. De Backer , I. Graham , M. R. Taskinen , O. Wiklund , S. Agewall , E. Alegria , M. J. Chapman , P. Durrington , et al . 2011 . ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur. Heart J. 32 : 1769 - 1818 .
    • (2011) Eur. Heart J. , vol.32 , pp. 1769-1818
    • Reiner, Z.1    Catapano, A.L.2    Backer, G.D.3    Graham, I.4    Taskinen, M.R.5    Wiklund, O.6    Agewall, S.7    Alegria, E.8    Chapman, M.J.9    Durrington, P.10


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