메뉴 건너뛰기




Volumn 10, Issue 10, 2015, Pages

HMGB1 contributes to the expression of P-Glycoprotein in mouse epileptic brain through toll-like receptor 4 and receptor for advanced glycation end products

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MULTIDRUG RESISTANCE PROTEIN; SN 50; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; KAINIC ACID; LIPOPOLYSACCHARIDE;

EID: 84948961996     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140918     Document Type: Article
Times cited : (51)

References (46)
  • 1
    • 34547828792 scopus 로고    scopus 로고
    • Development of new antiepileptic drugs: Challenges, incentives, and recent advances
    • Epub 2007/08/21
    • Perucca E, French J, Bialer M. Development of new antiepileptic drugs: challenges, incentives, and recent advances. The Lancet Neurology. 2007; 6(9):793-804. Epub 2007/08/21. doi: 10.1016/s1474-4422(07)70215-6 PMID: 17706563.
    • (2007) The Lancet Neurology. , vol.6 , Issue.9 , pp. 793-804
    • Perucca, E.1    French, J.2    Bialer, M.3
  • 2
    • 2342516133 scopus 로고    scopus 로고
    • Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy
    • PMID: 15101825
    • Aronica E, Gorter JA, Ramkema M, Redeker S, Ozbas-Gerceker F, van Vliet EA, et al. Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy. Epilepsia. 2004; 45(5):441-51. doi: 10.1111/j.0013-9580.2004.57703.x PMID: 15101825.
    • (2004) Epilepsia. , vol.45 , Issue.5 , pp. 441-451
    • Aronica, E.1    Gorter, J.A.2    Ramkema, M.3    Redeker, S.4    Ozbas-Gerceker, F.5    Van Vliet, E.A.6
  • 3
    • 16244367423 scopus 로고    scopus 로고
    • Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables
    • Epub 2005/04/05 PMID: 15805426
    • Volk H, Potschka H, Loscher W. Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables. The journal of histochemistry and cytochemistry: official journal of the Histochemistry Society. 2005; 53 (4):517-31. Epub 2005/04/05. doi: 10.1369/jhc.4A6451.2005 PMID: 15805426.
    • (2005) The Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society. , vol.53 , Issue.4 , pp. 517-531
    • Volk, H.1    Potschka, H.2    Loscher, W.3
  • 4
    • 79956347733 scopus 로고    scopus 로고
    • Potential role of multidrug resistant proteins in refractory epilepsy and antiepi-leptic drugs interactions
    • PMID: 21557674
    • Lazarowski A, Czornyj L. Potential role of multidrug resistant proteins in refractory epilepsy and antiepi-leptic drugs interactions. Drug metabolism and drug interactions. 2011; 26(1):21-6. doi: 10.1515/DMDI. 2011.006 PMID: 21557674.
    • (2011) Drug Metabolism and Drug Interactions. , vol.26 , Issue.1 , pp. 21-26
    • Lazarowski, A.1    Czornyj, L.2
  • 5
    • 72449177546 scopus 로고    scopus 로고
    • Signaling to P-glycoprotein-A new therapeutic target to treat drug-resistant epilepsy?
    • PMID: 19890496
    • Hartz AM, Notenboom S, Bauer B. Signaling to P-glycoprotein-A new therapeutic target to treat drug-resistant epilepsy? Drug news & perspectives. 2009; 22(7):393-7. doi: 10.1358/dnp.2009.22.7. 1401354 PMID: 19890496.
    • (2009) Drug News & Perspectives. , vol.22 , Issue.7 , pp. 393-397
    • Hartz, A.M.1    Notenboom, S.2    Bauer, B.3
  • 6
    • 77955316820 scopus 로고    scopus 로고
    • Modulating P-glycoprotein regulation: Future perspectives for pharmacoresistant epilepsies?
    • PMID: 20477844
    • Potschka H. Modulating P-glycoprotein regulation: future perspectives for pharmacoresistant epilepsies? Epilepsia. 2010; 51(8):1333-47. doi: 10.1111/j.1528-1167.2010.02585.x PMID: 20477844.
    • (2010) Epilepsia. , vol.51 , Issue.8 , pp. 1333-1347
    • Potschka, H.1
  • 7
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Epub 1993/01/01 PMID: 8102521
    • Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annual review of biochemistry. 1993; 62:385-427. Epub 1993/01/01. doi: 10.1146/annurev.bi.62. 070193.002125 PMID: 8102521.
    • (1993) Annual Review of Biochemistry. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 8
    • 20144379266 scopus 로고    scopus 로고
    • HIV-Tat protein induces P-glycoprotein expression in brain microvascular endothelial cells
    • Epub 2005/06/07 PMID: 15934943
    • Hayashi K, Pu H, Tian J, Andras IE, Lee YW, Hennig B, et al. HIV-Tat protein induces P-glycoprotein expression in brain microvascular endothelial cells. Journal of neurochemistry. 2005; 93(5):1231-41. Epub 2005/06/07. doi: 10.1111/j.1471-4159.2005.03114.x PMID: 15934943.
    • (2005) Journal of Neurochemistry. , vol.93 , Issue.5 , pp. 1231-1241
    • Hayashi, K.1    Pu, H.2    Tian, J.3    Andras, I.E.4    Lee, Y.W.5    Hennig, B.6
  • 9
    • 42449149172 scopus 로고    scopus 로고
    • Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signaling
    • PMID: 18094072
    • Bauer B, Hartz AM, Pekcec A, Toellner K, Miller DS, Potschka H. Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signaling. Molecular pharmacology. 2008; 73(5):1444-53. doi: 10.1124/mol.107.041210 PMID: 18094072.
    • (2008) Molecular Pharmacology. , vol.73 , Issue.5 , pp. 1444-1453
    • Bauer, B.1    Hartz, A.M.2    Pekcec, A.3    Toellner, K.4    Miller, D.S.5    Potschka, H.6
  • 10
    • 33847094700 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier
    • PMID: 17132686
    • Bauer B, Hartz AM, Miller DS. Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier. Molecular pharmacology. 2007; 71(3):667-75. doi: 10.1124/mol.106.029512 PMID: 17132686.
    • (2007) Molecular Pharmacology. , vol.71 , Issue.3 , pp. 667-675
    • Bauer, B.1    Hartz, A.M.2    Miller, D.S.3
  • 11
    • 84896517100 scopus 로고    scopus 로고
    • Extracellular high mobility group box chromosomal protein 1 promotes drug resistance by increasing the expression of Pglycoprotein expression in gastric adenocarcinoma cells
    • PMID: 24549588
    • Yin Y, Li W, Deng M, Zhang P, Shen Q, Wang G, et al. Extracellular high mobility group box chromosomal protein 1 promotes drug resistance by increasing the expression of Pglycoprotein expression in gastric adenocarcinoma cells. Molecular medicine reports. 2014; 9(4):1439-43. doi: 10. 3892/mmr.2014.1961 PMID: 24549588.
    • (2014) Molecular Medicine Reports. , vol.9 , Issue.4 , pp. 1439-1443
    • Yin, Y.1    Li, W.2    Deng, M.3    Zhang, P.4    Shen, Q.5    Wang, G.6
  • 12
    • 84864305538 scopus 로고    scopus 로고
    • Inflammation and epilepsy: The foundations for a new therapeutic approach in epilepsy?
    • PMID: 22368518; PubMed Central PMCID: PMC3280476
    • Walker L, Sills GJ. Inflammation and epilepsy: the foundations for a new therapeutic approach in epilepsy? Epilepsy currents/American Epilepsy Society. 2012; 12(1):8-12. doi: 10.5698/1535-7511-12.1. 8 PMID: 22368518; PubMed Central PMCID: PMC3280476.
    • (2012) Epilepsy Currents/American Epilepsy Society. , vol.12 , Issue.1 , pp. 8-12
    • Walker, L.1    Sills, G.J.2
  • 13
    • 80053028698 scopus 로고    scopus 로고
    • Interleukin-1 type 1 receptor/Toll-like receptor signalling in epilepsy: The importance of IL-1beta and high-mobility group box 1
    • PMID: 21793950
    • Maroso M, Balosso S, Ravizza T, Liu J, Bianchi ME, Vezzani A. Interleukin-1 type 1 receptor/Toll-like receptor signalling in epilepsy: the importance of IL-1beta and high-mobility group box 1. Journal of internal medicine. 2011; 270(4):319-26. doi: 10.1111/j.1365-2796.2011.02431.x PMID: 21793950.
    • (2011) Journal of Internal Medicine. , vol.270 , Issue.4 , pp. 319-326
    • Maroso, M.1    Balosso, S.2    Ravizza, T.3    Liu, J.4    Bianchi, M.E.5    Vezzani, A.6
  • 14
    • 84897933220 scopus 로고    scopus 로고
    • Epilepsy and inflammation in the brain: Overview and pathophysiology
    • PMID: 24955068; PubMed Central PMCID: PMC3966641
    • Vezzani A. Epilepsy and inflammation in the brain: overview and pathophysiology. Epilepsy currents/American Epilepsy Society. 2014; 14(1 Suppl):3-7. doi: 10.5698/1535-7511-14.s2.3 PMID: 24955068; PubMed Central PMCID: PMC3966641.
    • (2014) Epilepsy Currents/American Epilepsy Society. , vol.14 , Issue.1 , pp. 3-7
    • Vezzani, A.1
  • 15
    • 77950539231 scopus 로고    scopus 로고
    • Toll-like receptor4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures
    • PMID: 20348922
    • Maroso M, Balosso S, Ravizza T, Liu J, Aronica E, Iyer AM, et al. Toll-like receptor4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures. Nature medicine. 2010; 16(4):413-9. doi: 10.1038/nm.2127 PMID: 20348922.
    • (2010) Nature Medicine. , vol.16 , Issue.4 , pp. 413-419
    • Maroso, M.1    Balosso, S.2    Ravizza, T.3    Liu, J.4    Aronica, E.5    Iyer, A.M.6
  • 17
    • 0036776077 scopus 로고    scopus 로고
    • Transient increase of P-glycoprotein expression in endothelium and parenchyma of limbic brain regions in the kainate model of temporal lobe epilepsy
    • Epub 2002/10/26. PMID: 12399076
    • Seegers U, Potschka H, Loscher W. Transient increase of P-glycoprotein expression in endothelium and parenchyma of limbic brain regions in the kainate model of temporal lobe epilepsy. Epilepsy research. 2002; 51(3):257-68. Epub 2002/10/26. PMID: 12399076.
    • (2002) Epilepsy Research. , vol.51 , Issue.3 , pp. 257-268
    • Seegers, U.1    Potschka, H.2    Loscher, W.3
  • 19
    • 84898738420 scopus 로고    scopus 로고
    • The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases
    • PMID: 24531836; PubMed Central PMCID: PMC3966993
    • Magna M, Pisetsky DS. The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases. Molecular medicine. 2014; 20:138-46. doi: 10.2119/molmed.2013.00164 PMID: 24531836; PubMed Central PMCID: PMC3966993.
    • (2014) Molecular Medicine. , vol.20 , pp. 138-146
    • Magna, M.1    Pisetsky, D.S.2
  • 20
    • 77956929099 scopus 로고    scopus 로고
    • Important aspects of Toll-like receptors, ligands and their signaling pathways
    • Epub 2010/07/02 PMID: 20593217
    • Chang ZL. Important aspects of Toll-like receptors, ligands and their signaling pathways. Inflammation research: official journal of the European Histamine Research Society [et al]. 2010; 59(10):791-808. Epub 2010/07/02. doi: 10.1007/s00011-010-0208-2 PMID: 20593217.
    • (2010) Inflammation Research: Official Journal of the European Histamine Research Society [Et Al]. , vol.59 , Issue.10 , pp. 791-808
    • Chang, Z.L.1
  • 21
    • 84881118554 scopus 로고    scopus 로고
    • Cellular signalling of the receptor for advanced glycation end products (RAGE)
    • Epub 2013/07/11 PMID: 23838007
    • Xie J, Mendez JD, Mendez-Valenzuela V, Aguilar-Hernandez MM. Cellular signalling of the receptor for advanced glycation end products (RAGE). Cellular signalling. 2013; 25(11):2185-97. Epub 2013/07/11. doi: 10.1016/j.cellsig.2013.06.013 PMID: 23838007.
    • (2013) Cellular Signalling. , vol.25 , Issue.11 , pp. 2185-2197
    • Xie, J.1    Mendez, J.D.2    Mendez-Valenzuela, V.3    Aguilar-Hernandez, M.M.4
  • 22
    • 84879735457 scopus 로고    scopus 로고
    • Receptor for Advanced Glycation End-products is upregulated in temporal lobe epilepsy and contributes to experimental seizures
    • PMID: 23523633
    • Iori V, Maroso M, Rizzi M, Iyer AM, Vertemara R, Carli M, et al. Receptor for Advanced Glycation End-products is upregulated in temporal lobe epilepsy and contributes to experimental seizures. Neurobiology of disease. 2013; 58:102-14. doi: 10.1016/j.nbd.2013.03.006 PMID: 23523633.
    • (2013) Neurobiology of Disease. , vol.58 , pp. 102-114
    • Iori, V.1    Maroso, M.2    Rizzi, M.3    Iyer, A.M.4    Vertemara, R.5    Carli, M.6
  • 23
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappaBand i kappa B proteins: New discoveries and insights
    • PMID: 8717528
    • Baldwin AS Jr. The NF-kappaBand I kappa B proteins: new discoveries and insights. Annual review of immunology. 1996; 14:649-83. doi: 10.1146/annurev.immunol.14.1.649 PMID: 8717528.
    • (1996) Annual Review of Immunology. , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 25
    • 79955049801 scopus 로고    scopus 로고
    • Nuclear factor-kappa B activity regulates brain expression of P-glycoprotein in the kainic acid-induced seizure rats
    • PMID: 21403895; PubMed Central PMCID: PMC3043292
    • Yu N, Di Q, Liu H, Hu Y, Jiang Y, Yan YK, et al. Nuclear factor-kappa B activity regulates brain expression of P-glycoprotein in the kainic acid-induced seizure rats. Mediators of inflammation. 2011; 2011:670613. doi: 10.1155/2011/670613 PMID: 21403895; PubMed Central PMCID: PMC3043292.
    • (2011) Mediators of Inflammation. , vol.2011 , pp. 670613
    • Yu, N.1    Di Liu Q, H.2    Hu, Y.3    Jiang, Y.4    Yan, Y.K.5
  • 26
    • 35448940367 scopus 로고    scopus 로고
    • Nuclear factor-kappa B regulates seizure threshold and gene transcription following convulsant stimulation
    • PMID: 17727632
    • Lubin FD, Ren Y, Xu X, Anderson AE. Nuclear factor-kappa B regulates seizure threshold and gene transcription following convulsant stimulation. Journal of neurochemistry. 2007; 103(4):1381-95. doi: 10.1111/j.1471-4159.2007.04863.x PMID: 17727632.
    • (2007) Journal of Neurochemistry. , vol.103 , Issue.4 , pp. 1381-1395
    • Lubin, F.D.1    Ren, Y.2    Xu, X.3    Anderson, A.E.4
  • 27
    • 84865300659 scopus 로고    scopus 로고
    • Lipopolysaccharide appears to activate human endometrial endothelial cells through TLR-4-dependent and TLR-4-independent mechanisms
    • Epub 2012/06/08 PMID: 22672000; PubMed Central PMCID: PMCPmc3418410
    • Krikun G, Trezza J, Shaw J, Rahman M, Guller S, Abrahams VM, et al. Lipopolysaccharide appears to activate human endometrial endothelial cells through TLR-4-dependent and TLR-4-independent mechanisms. American journal of reproductive immunology. 2012; 68(3):233-7. Epub 2012/06/08. doi: 10. 1111/j.1600-0897.2012.01164.x PMID: 22672000; PubMed Central PMCID: PMCPmc3418410.
    • (2012) American Journal of Reproductive Immunology. , vol.68 , Issue.3 , pp. 233-237
    • Krikun, G.1    Trezza, J.2    Shaw, J.3    Rahman, M.4    Guller, S.5    Abrahams, V.M.6
  • 28
    • 84859723641 scopus 로고    scopus 로고
    • A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease
    • Epub 2012/03/13 PMID: 22406537; PubMed Central PMCID: PMCPmc3314449
    • Deane R, Singh I, Sagare AP, Bell RD, Ross NT, La Rue B, et al. A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease. The Journal of clinical investigation. 2012; 122(4):1377-92. Epub 2012/03/13. doi: 10.1172/jci58642 PMID: 22406537; PubMed Central PMCID: PMCPmc3314449.
    • (2012) The Journal of Clinical Investigation. , vol.122 , Issue.4 , pp. 1377-1392
    • Deane, R.1    Singh, I.2    Sagare, A.P.3    Bell, R.D.4    Ross, N.T.5    La Rue, B.6
  • 29
    • 33745728301 scopus 로고    scopus 로고
    • From willow bark to peptides: The ever widening spectrum of NF-kappaB inhibitors
    • Epub 2006/06/20 PMID: 16781194
    • DAcquisto F, Ianaro A. From willow bark to peptides: the ever widening spectrum of NF-kappaB inhibitors. Current opinion in pharmacology. 2006; 6(4):387-92. Epub 2006/06/20. doi: 10.1016/j.coph.2006. 02.009 PMID: 16781194.
    • (2006) Current Opinion in Pharmacology. , vol.6 , Issue.4 , pp. 387-392
    • DAcquisto, F.1    Ianaro, A.2
  • 31
    • 0003584850 scopus 로고    scopus 로고
    • Paxinos KBJFa G London UK: Elsevier Academic Press
    • Paxinos KBJFa G. The Mouse Brain in Stereotaxic Coordinate London, UK: Elsevier Academic Press; 2007.
    • (2007) The Mouse Brain in Stereotaxic Coordinate
  • 32
    • 58149105502 scopus 로고    scopus 로고
    • A novel non-transcrip-tional pathway mediates the proconvulsive effects of interleukin-1beta
    • PMID: 18952671; PubMed Central PMCID: PMC2724908
    • Balosso S, Maroso M, Sanchez-Alavez M, Ravizza T, Frasca A, Bartfai T, et al. A novel non-transcrip-tional pathway mediates the proconvulsive effects of interleukin-1beta. Brain: a journal of neurology. 2008; 131(Pt 12):3256-65. doi: 10.1093/brain/awn271 PMID: 18952671; PubMed Central PMCID: PMC2724908.
    • (2008) Brain: A Journal of Neurology. , vol.131 , pp. 3256-3265
    • Balosso, S.1    Maroso, M.2    Sanchez-Alavez, M.3    Ravizza, T.4    Frasca, A.5    Bartfai, T.6
  • 33
    • 84904514354 scopus 로고    scopus 로고
    • Effects of brain IKKbeta gene silencing by small interfering RNAon P-glycoprotein expression and brain damage in the rat kainic acid-induced seizure model
    • PMID: 24040792
    • Yu N, Liu H, Zhang YF, Su LY, Liu XH, Li LC, et al. Effects of brain IKKbeta gene silencing by small interfering RNAon P-glycoprotein expression and brain damage in the rat kainic acid-induced seizure model. CNS& neurological disorders drug targets. 2014; 13(4):661-72. PMID: 24040792.
    • (2014) CNS& Neurological Disorders Drug Targets. , vol.13 , Issue.4 , pp. 661-672
    • Yu, N.1    Liu, H.2    Zhang, Y.F.3    Su, L.Y.4    Liu, X.H.5    Li, L.C.6
  • 34
    • 0024405955 scopus 로고
    • Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment
    • PMID: 2736622
    • Williams RL, Risau W, Zerwes HG, Drexler H, Aguzzi A, Wagner EF. Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment. Cell. 1989; 57(6):1053-63. PMID: 2736622.
    • (1989) Cell. , vol.57 , Issue.6 , pp. 1053-1063
    • Williams, R.L.1    Risau, W.2    Zerwes, H.G.3    Drexler, H.4    Aguzzi, A.5    Wagner, E.F.6
  • 35
    • 0141894132 scopus 로고    scopus 로고
    • Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies
    • PMID: 14568334
    • Omidi Y, Campbell L, Barar J, Connell D, Akhtar S, Gumbleton M. Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies. Brain research. 2003; 990(1-2):95-112. PMID: 14568334.
    • (2003) Brain Research. , vol.990 , Issue.1-2 , pp. 95-112
    • Omidi, Y.1    Campbell, L.2    Barar, J.3    Connell, D.4    Akhtar, S.5    Gumbleton, M.6
  • 36
    • 0037089098 scopus 로고    scopus 로고
    • Modifications in astrocyte morphology and calcium signaling induced by a brain capillary endothelial cell line
    • PMID: 11948807
    • Yoder EJ. Modifications in astrocyte morphology and calcium signaling induced by a brain capillary endothelial cell line. Glia. 2002; 38(2):137-45. PMID: 11948807.
    • (2002) Glia. , vol.38 , Issue.2 , pp. 137-145
    • Yoder, E.J.1
  • 37
    • 84875617631 scopus 로고    scopus 로고
    • Glutathione prevents free fatty acids-induced oxidative stress and apoptosis in human brain vascular endothelial cells through Akt pathway
    • PMID: 23521913
    • Zhou HG, Liu L, Zhang Y, Huang YY, Tao YH, Zhang S, et al. Glutathione prevents free fatty acids-induced oxidative stress and apoptosis in human brain vascular endothelial cells through Akt pathway. CNS neuroscience & therapeutics. 2013; 19(4):252-61. doi: 10.1111/cns.12068 PMID: 23521913.
    • (2013) CNS Neuroscience & Therapeutics. , vol.19 , Issue.4 , pp. 252-261
    • Zhou, H.G.1    Liu, L.2    Zhang, Y.3    Huang, Y.Y.4    Tao, Y.H.5    Zhang, S.6
  • 38
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • PMID: 11846609
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001; 25(4):402-8. doi: 10.1006/meth.2001.1262 PMID: 11846609.
    • (2001) Methods. , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 39
    • 0037096732 scopus 로고    scopus 로고
    • Hypoxia-induciblefactor-1-dependent regulation of the multidrug resistance (MDR1) gene
    • PMID: 12067980
    • Comerford KM, Wallace TJ, Karhausen J, Louis NA, Montalto MC, Colgan SP. Hypoxia-induciblefac-tor-1-dependent regulation of the multidrug resistance (MDR1) gene. Cancer research. 2002; 62 (12):3387-94. PMID: 12067980.
    • (2002) Cancer Research. , vol.62 , Issue.12 , pp. 3387-3394
    • Comerford, K.M.1    Wallace, T.J.2    Karhausen, J.3    Louis, N.A.4    Montalto, M.C.5    Colgan, S.P.6
  • 40
    • 79955137781 scopus 로고    scopus 로고
    • Upregulation of mdr1 gene is related to activation of the MAPK/ERK signal transduction pathway and YB-1 nuclear translocation in B-cell lymphoma
    • PMID: 21300134
    • Shen H, Xu W, Luo W, Zhou L, Yong W, Chen F, et al. Upregulation of mdr1 gene is related to activation of the MAPK/ERK signal transduction pathway and YB-1 nuclear translocation in B-cell lymphoma. Experimental hematology. 2011; 39(5):558-69. doi: 10.1016/j.exphem.2011.01.013 PMID: 21300134.
    • (2011) Experimental Hematology. , vol.39 , Issue.5 , pp. 558-569
    • Shen, H.1    Xu, W.2    Luo, W.3    Zhou, L.4    Yong, W.5    Chen, F.6
  • 41
    • 0034698830 scopus 로고    scopus 로고
    • High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
    • PMID: 10952726; PubMed Central PMCID: PMC2193240
    • Andersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, Erlandsson-Harris H, et al. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. The Journal of experimental medicine. 2000; 192(4):565-70. PMID: 10952726; PubMed Central PMCID: PMC2193240.
    • (2000) The Journal of Experimental Medicine. , vol.192 , Issue.4 , pp. 565-570
    • Andersson, U.1    Wang, H.2    Palmblad, K.3    Aveberger, A.C.4    Bloom, O.5    Erlandsson-Harris, H.6
  • 42
    • 78449272659 scopus 로고    scopus 로고
    • Statins attenuate high mobility group box-1 protein induced vascular endothelial activation: A key role for TLR4/NF-kappaB signaling pathway
    • PMID: 20714791
    • Yang J, Huang C, Yang J, Jiang H, Ding J. Statins attenuate high mobility group box-1 protein induced vascular endothelial activation: a key role for TLR4/NF-kappaB signaling pathway. Molecular and cellular biochemistry. 2010; 345(1-2):189-95. doi: 10.1007/s11010-010-0572-9 PMID: 20714791.
    • (2010) Molecular and Cellular Biochemistry. , vol.345 , Issue.1-2 , pp. 189-195
    • Yang, J.1    Huang, C.2    Yang, J.3    Jiang, H.4    Ding, J.5
  • 43
    • 0346729785 scopus 로고    scopus 로고
    • Neuronal expression of the drug efflux transporter P-glycoprotein in the rat hippocampus after limbic seizures
    • PMID: 14706787
    • Volk HA, Burkhardt K, Potschka H, Chen J, Becker A, Loscher W. Neuronal expression of the drug efflux transporter P-glycoprotein in the rat hippocampus after limbic seizures. Neuroscience. 2004; 123 (3):751-9. PMID: 14706787.
    • (2004) Neuroscience. , vol.123 , Issue.3 , pp. 751-759
    • Volk, H.A.1    Burkhardt, K.2    Potschka, H.3    Chen, J.4    Becker, A.5    Loscher, W.6
  • 44
    • 0032972644 scopus 로고    scopus 로고
    • Induction of P-glycoprotein expression in astrocytes following intracerebro-ventricular kainate injections
    • Epub 1999/07/28. PMID: 10422714
    • Zhang L, Ong WY, Lee T. Induction of P-glycoprotein expression in astrocytes following intracerebro-ventricular kainate injections. Experimental brain research. 1999; 126(4):509-16. Epub 1999/07/28. PMID: 10422714.
    • (1999) Experimental Brain Research. , vol.126 , Issue.4 , pp. 509-516
    • Zhang, L.1    Ong, W.Y.2    Lee, T.3
  • 45
    • 77951673449 scopus 로고    scopus 로고
    • Regulation of P-glycoprotein in renal proximal tubule epithelial cells by LPS and TNF-alpha
    • PMID: 20300455; PubMed Central PMCID: PMC2841251
    • Heemskerk S, Peters JG, Louisse J, Sagar S, Russel FG, Masereeuw R. Regulation of P-glycoprotein in renal proximal tubule epithelial cells by LPS and TNF-alpha. Journal of biomedicine & biotechnology. 2010; 2010:525180. doi: 10.1155/2010/525180 PMID: 20300455; PubMed Central PMCID: PMC2841251.
    • (2010) Journal of Biomedicine & Biotechnology. , vol.2010 , pp. 525180
    • Heemskerk, S.1    Peters, J.G.2    Louisse, J.3    Sagar, S.4    Russel, F.G.5    Masereeuw, R.6
  • 46
    • 77956010858 scopus 로고    scopus 로고
    • Cox-2 inhibition can lead to adverse effects in a rat model for temporal lobe epilepsy
    • PMID: 20643531
    • Holtman L, van Vliet EA, Edelbroek PM, Aronica E, Gorter JA. Cox-2 inhibition can lead to adverse effects in a rat model for temporal lobe epilepsy. Epilepsy research. 2010; 91(1):49-56. doi: 10.1016/j. eplepsyres.2010.06.011 PMID: 20643531.
    • (2010) Epilepsy Research. , vol.91 , Issue.1 , pp. 49-56
    • Holtman, L.1    Van Vliet, E.A.2    Edelbroek, P.M.3    Aronica, E.4    Gorter, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.