Use and effects of cannabinoids in military veterans with posttraumatic stress disorder

American Journal of Health-System Pharmacy

Volumn 72, Issue 15, 2015, Pages 1279-1284

  Betthauser, Kevin ^a   Pilz, Jeffrey ^b   Vollmer, Laura E ^c  

^a BARNES JEWISH HOSPITAL   (United States)

^b UNIVERSITY OF KANSAS HOSPITAL   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID; MEDICAL CANNABIS;

ARMY; ARTICLE; CHRONIC PAIN; COPING BEHAVIOR; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; DRUG MECHANISM; DSM-5; DSM-IV; GENERALIZED ANXIETY DISORDER; HUMAN; INSOMNIA; MAJOR DEPRESSION; NEUROTRANSMITTER RELEASE; NIGHTMARE; PATHOGENESIS; PATHOPHYSIOLOGY; PERSONAL EXPERIENCE; POSTTRAUMATIC STRESS DISORDER; PREVALENCE; PRIORITY JOURNAL; SUBSTANCE ABUSE; VETERAN; RANDOMIZED CONTROLLED TRIAL (TOPIC); STRESS DISORDERS, POST-TRAUMATIC; UNITED STATES;

CANNABINOIDS; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; STRESS DISORDERS, POST-TRAUMATIC; UNITED STATES; VETERANS;

EID: 84948712574     PISSN: 10792082     EISSN: 15352900     Source Type: Journal    
DOI: 10.2146/ajhp140523     Document Type: Article

References (21)

1. O'Brien CP. Drug addiction. In: Brunton L, ed. Goodman & Gilman's the pharmacological basis of therapeutics. 12th ed. New York: McGraw-Hill; 2011:663- 4.
2. Bonn-Miller MO, Vujanovic AA, Drescher KD. Cannabis use among military veterans after residential treatment for posttraumatic stress disorder. Psychol Addict Behnv. 2011; 25:485-91.
3. Greer GR, Grob CS, Halberstadt AL. PTSD symptom reports of patients evaluated for the New Mexico Medical Cannabis Program. J Psychoactive Drugs. 2014;46:73-7.
4. Mashiah M. Medical cannabis as treatment for chronic combat PTSD: promising results in an open pilot study. Presentation at Patients Out of Time Conference, Tucson, AZ; 2012 Apr 28.
5. Bonn-Miller MO, Vujanovic AA, Boden MT et al. Post-traumatic stress, difficulties in emotion regulation, and coping- oriented marijuana use. Cogn Behav Thcr. 2011;40:34-44.
6. Yehuda R. Post-traumatic stress disorder. N Engl J Med. 2002; 346:108-14.
7. Galea S, Nandi A, Viahov D. The epidemiology of post-traumatic stress disorder after disasters. Epidemiol Rev. 2005; 27:78-91.
8. Department of Veterans Affairs National Center for PTSD. How common is PTSD? Frequently asked questionswww.ptsd.va.gov/public/PTSD-overview/basics/how-common-is-ptsd.asp (accessed 2013 Feb 20).
9. Bonn-Miller MO, Boden MT, Vujanovic AA. Prospective investigation of the impact of cannabis use disorders on post-traumatic stress disorder symptoms among veterans in residential treatment. Psychol Trauma. 2013; 5:193-200.
10. Porth CM. Essentials of pathophysiology. 3rd ed. Philadelphia: Wolters Kluwer Health; 2011:219-22.
11. Marsicano G, Wotjak CT, Azad CA et al. The endogenous cannabinoid system controls extinction of aversive memories. Nature. 2002;418:530-4.
12. Trezza V, Campologno P. The endocan- nabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD). Front Behav Neurosci. 2013; 7:1 -6.
13. Yehuda R. Biology of post-traumatic stress disorder. I Clin Psychiatry. 2000; 61:14-21.
14. Seamon MJ, Fass JA, Maniscalco-Feichtl M et al. Medical marijuana and the developing role of the pharmacist. Am J Health-Syst Pharm. 2007; 64:1037-44.
15. Abood RR. Pharmacy practice and the law. 7th ed. Burlington, MA: Jones and Bartlett Learning; 2014:184-216.
16. Bonn-Miller MO, Vujanovic AA, Feldner MT et al. Post-traumatic stress symptom severity predicts marijuana use coping motives among traumatic event-exposed marijuana users. Trauma Stress. 2007; 20:577-86.
17. Bonn-Miller MO, Babson KA, Vandrey R. Using cannabis to help you sleep: heightened frequency of medical cannabis use among those with PTSD. Drug Alcohol Depend. 2014; 136:162-5.
18. Potter CM, Vujanovic AA, Marshall- Berenz EC et al. Post-traumatic stress and marijuana use coping motives: The mediating role of distress tolerance. J Anxiety Disord. 2011; 25:437-43.
19. Bremner JD, Southwick SM, Darnell A et al. Chronic PTSD in Vietnam combat veterans: course of illness and substance abuse. Am J Psychiatry. 1996; 153:369- 75.
20. Cameron C, Watson D, Robinson J. Use of a synthetic cannabinoid in a correctional population for posttraumatic stress disorder-related insomnia and nightmares, chronic pain, harm reduction, and indications: A retrospective evaluation. Clin Psychopharmacol. 2014; 34:559-64.
21. Fraser G. The use of a synthetic cannabinoid in the management of treatment- resistant nightmares in post-traumatic stress disorder (PTSD). I CNS Neurosci Ther. 2009; 15:84-8.