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Volumn 10, Issue 4, 2015, Pages 651-654

Effects of Three Months Fingolimod Therapy on Heart Rate

Author keywords

Disease modifying therapies; Fingolimod; Heart rate; Multiple sclerosis

Indexed keywords

FINGOLIMOD; IMMUNOSUPPRESSIVE AGENT;

EID: 84948575488     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-015-9619-8     Document Type: Article
Times cited : (12)

References (18)
  • 1
    • 0042655124 scopus 로고    scopus 로고
    • Circadian profile of cardiac autonomic nervous modulation in healthy subjects: differing effects of aging and gender on heart rate variability
    • PID: 12890036
    • Bonnemeier H, Richardt G, Potratz J et al (2003) Circadian profile of cardiac autonomic nervous modulation in healthy subjects: differing effects of aging and gender on heart rate variability. J Cardiovasc Electrophysiol 14:791–799
    • (2003) J Cardiovasc Electrophysiol , vol.14 , pp. 791-799
    • Bonnemeier, H.1    Richardt, G.2    Potratz, J.3
  • 2
    • 34250832664 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology
    • COI: 1:CAS:528:DC%2BD2sXntFyiur0%3D, PID: 17561264
    • Brinkmann V (2007) Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology. Pharmacol Ther 115:84–105
    • (2007) Pharmacol Ther , vol.115 , pp. 84-105
    • Brinkmann, V.1
  • 3
    • 78049480679 scopus 로고    scopus 로고
    • Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
    • COI: 1:CAS:528:DC%2BC3cXhtlCqsr%2FL, PID: 21031003
    • Brinkmann V, Billich A, Baumruker T et al (2010) Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis. Nat Rev Drug Discov 9:883–897
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 883-897
    • Brinkmann, V.1    Billich, A.2    Baumruker, T.3
  • 4
    • 84901197534 scopus 로고    scopus 로고
    • Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a double-blind, randomized, placebo-controlled, phase 3 trial
    • COI: 1:CAS:528:DC%2BC2cXltl2msbc%3D, PID: 24685276
    • Calabresi PA, Radue EW, Goodin D et al (2014) Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a double-blind, randomized, placebo-controlled, phase 3 trial. Lancet Neurol 13:545–556
    • (2014) Lancet Neurol , vol.13 , pp. 545-556
    • Calabresi, P.A.1    Radue, E.W.2    Goodin, D.3
  • 5
    • 84908323531 scopus 로고    scopus 로고
    • Cardiac and vascular effects of fingolimod: mechanistic basis and clinical implications
    • COI: 1:CAS:528:DC%2BC2cXhsFSjtbvF, PID: 25440790
    • Camm J, Hla T, Bakshi R, Brinkkman V (2014) Cardiac and vascular effects of fingolimod: mechanistic basis and clinical implications. Am Heart J 168:632–634
    • (2014) Am Heart J , vol.168 , pp. 632-634
    • Camm, J.1    Hla, T.2    Bakshi, R.3    Brinkkman, V.4
  • 6
    • 77951073508 scopus 로고    scopus 로고
    • Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis
    • COI: 1:CAS:528:DC%2BC3cXksFSgt7g%3D, PID: 20061941
    • Chun J, Hartung HP (2010) Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis. Clin Neuropharmacol 33:91–101
    • (2010) Clin Neuropharmacol , vol.33 , pp. 91-101
    • Chun, J.1    Hartung, H.P.2
  • 7
    • 76149140914 scopus 로고    scopus 로고
    • Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
    • COI: 1:CAS:528:DC%2BC3cXhvVWrsbk%3D, PID: 20089954
    • Cohen JA, Barkhof F, Comi G et al (2010) Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med 362:402–415
    • (2010) N Engl J Med , vol.362 , pp. 402-415
    • Cohen, J.A.1    Barkhof, F.2    Comi, G.3
  • 8
    • 76149093586 scopus 로고    scopus 로고
    • A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis
    • COI: 1:CAS:528:DC%2BC3cXhvVWltr4%3D, PID: 20089952
    • Kappos L, Radue EW, O’Connor P et al (2010) A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis. N Engl J Med 362:387–401
    • (2010) N Engl J Med , vol.362 , pp. 387-401
    • Kappos, L.1    Radue, E.W.2    O’Connor, P.3
  • 9
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS)
    • COI: 1:STN:280:DyaL2c%2FktValsQ%3D%3D, PID: 6685237
    • Kurtzke JF (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33:1444–1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 10
    • 79958262718 scopus 로고    scopus 로고
    • The circadian pattern of cardiac autonomic modulation in a middle-aged population
    • COI: 1:CAS:528:DC%2BC3MXit1ynsg%3D%3D
    • Li X, Shaffer ML, Rodriguez-Colon S et al (2011) The circadian pattern of cardiac autonomic modulation in a middle-aged population. Clin Auton Res 3:143–150
    • (2011) Clin Auton Res , vol.3 , pp. 143-150
    • Li, X.1    Shaffer, M.L.2    Rodriguez-Colon, S.3
  • 11
    • 0037066466 scopus 로고    scopus 로고
    • Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
    • COI: 1:CAS:528:DC%2BD38XjtVWhsrc%3D, PID: 11923495
    • Mandala S, Hajdu R, Bergstrom J et al (2002) Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science 296:346–349
    • (2002) Science , vol.296 , pp. 346-349
    • Mandala, S.1    Hajdu, R.2    Bergstrom, J.3
  • 12
    • 33748695513 scopus 로고    scopus 로고
    • Fingolimod and sphingosine-1-phosphate-modifiers of lymphocyte migration
    • COI: 1:CAS:528:DC%2BD28XpsFKlsLs%3D, PID: 16971715
    • Massberg S, von Andrian UH (2006) Fingolimod and sphingosine-1-phosphate-modifiers of lymphocyte migration. N Engl J Med 355:1088–1091
    • (2006) N Engl J Med , vol.355 , pp. 1088-1091
    • Massberg, S.1    von Andrian, U.H.2
  • 13
    • 34247874512 scopus 로고    scopus 로고
    • Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteosomal degradation of the receptor
    • COI: 1:CAS:528:DC%2BD2sXivV2mt70%3D, PID: 17237497
    • Oo L, Thangada S, Wu M-T et al (2007) Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteosomal degradation of the receptor. J Biol Chem 282:9082–9089
    • (2007) J Biol Chem , vol.282 , pp. 9082-9089
    • Oo, L.1    Thangada, S.2    Wu, M.-T.3
  • 14
    • 84856249964 scopus 로고    scopus 로고
    • Fingolimod for multiple sclerosis
    • COI: 1:CAS:528:DC%2BC38Xhs1artLc%3D, PID: 22276823
    • Pelletier D, Hafler DA (2012) Fingolimod for multiple sclerosis. N Engl J Med 366:339–347
    • (2012) N Engl J Med , vol.366 , pp. 339-347
    • Pelletier, D.1    Hafler, D.A.2
  • 15
    • 84923093812 scopus 로고    scopus 로고
    • The autonomic balance predicts cardiac responses after the first dose of fingolimod
    • COI: 1:STN:280:DC%2BC2cfltVKntQ%3D%3D, PID: 24957049
    • Rossi S, Rocchi C, Studer V et al (2015) The autonomic balance predicts cardiac responses after the first dose of fingolimod. Mult Scler 21:206–216
    • (2015) Mult Scler , vol.21 , pp. 206-216
    • Rossi, S.1    Rocchi, C.2    Studer, V.3
  • 16
    • 84860284278 scopus 로고    scopus 로고
    • Placebo-controlled study of the effects of fingolimod on cardiac rate and rhythm and pulmonary function in healthy volunteers
    • PID: 22071882
    • Schmouder R, Hariry S, David OJ (2011) Placebo-controlled study of the effects of fingolimod on cardiac rate and rhythm and pulmonary function in healthy volunteers. Eur J Clin Pharmacol 68:355–362
    • (2011) Eur J Clin Pharmacol , vol.68 , pp. 355-362
    • Schmouder, R.1    Hariry, S.2    David, O.J.3
  • 17
    • 84905562170 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple sclerosis
    • COI: 1:CAS:528:DC%2BC2cXkvV2lt74%3D
    • Sic H, Kraus H, Madl J et al (2014) Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple sclerosis. J Clin Allergy Immunol 134:420–428
    • (2014) J Clin Allergy Immunol , vol.134 , pp. 420-428
    • Sic, H.1    Kraus, H.2    Madl, J.3
  • 18
    • 0020077038 scopus 로고
    • Ambulatory electrocardiographic recordings in endurance athletes
    • COI: 1:STN:280:DyaL387jsFWmsg%3D%3D, PID: 7059398
    • Viitasalo MT, Kala R, Eisalo A (1982) Ambulatory electrocardiographic recordings in endurance athletes. Br Heart J 47:213–220
    • (1982) Br Heart J , vol.47 , pp. 213-220
    • Viitasalo, M.T.1    Kala, R.2    Eisalo, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.