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Volumn 21, Issue 6, 2015, Pages 506-509

Toxicities associated with adoptive t-cell transfer for cancer

Author keywords

Acute cytokine release; Autoimmune complications; Cancer; Cultured immune cells; Infection; Off target toxicities; Toxicities

Indexed keywords

ANTINEOPLASTIC AGENT; AUTOANTIGEN; CORTICOSTEROID; CYTOKINE; IMMUNOSUPPRESSIVE AGENT; IPILIMUMAB; PROTEOME; RECOMBINANT INTERLEUKIN 2; TOCILIZUMAB; VIRUS ANTIGEN;

EID: 84948429019     PISSN: 15289117     EISSN: 1540336X     Source Type: Journal    
DOI: 10.1097/PPO.0000000000000157     Document Type: Review
Times cited : (43)

References (33)
  • 2
    • 20044363610 scopus 로고    scopus 로고
    • + T helper cells and hindered by naturally occurring T regulatory cells
    • + T helper cells and hindered by naturally occurring T regulatory cells. J Ismmunol. 2005; 174: 2591-2601.
    • (2005) J Ismmunol , vol.174 , pp. 2591-2601
    • Antony, P.A.1    Piccirillo, C.A.2    Akpinarli, A.3
  • 3
    • 12744253307 scopus 로고    scopus 로고
    • Sinks, suppressors and antigen presenters: How lymphodepletion enhances T cell-mediated tumor immunotherapy
    • Klebanoff CA, KhongHT, Antony PA, et al. Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy. Trends Immunol. 2005; 26: 111-117.
    • (2005) Trends Immunol , vol.26 , pp. 111-117
    • Klebanoff, C.A.1    Khonght Antony, P.A.2
  • 4
    • 0037174674 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
    • Dudley ME, Wunderlich JR, Robbins PF, et al. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science. 2002; 298: 850-854.
    • (2002) Science , vol.298 , pp. 850-854
    • Dudley, M.E.1    Wunderlich, J.R.2    Robbins, P.F.3
  • 5
    • 55949125601 scopus 로고    scopus 로고
    • Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
    • Dudley ME, Yang JC, Sherry R, et al. Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J Clin Oncol. 2008; 26: 5233-5239.
    • (2008) J Clin Oncol , vol.26 , pp. 5233-5239
    • Dudley, M.E.1    Yang, J.C.2    Sherry, R.3
  • 6
    • 84887991307 scopus 로고    scopus 로고
    • +-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma
    • +-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma. J Clin Oncol. 2013; 31: 2152-2159.
    • (2013) J Clin Oncol , vol.31 , pp. 2152-2159
    • Dudley, M.E.1    Gross, C.A.2    Somerville, R.P.3
  • 7
    • 84876325876 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
    • Grupp SA, Kalos M, Barrett D, et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl JMed. 2013; 368: 1509-1518.
    • (2013) N Engl JMed , vol.368 , pp. 1509-1518
    • Grupp, S.A.1    Kalos, M.2    Barrett, D.3
  • 8
    • 33744792341 scopus 로고    scopus 로고
    • Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
    • Beck KE, Blansfield JA, Tran KQ, et al. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. J Clin Oncol. 2006; 24: 2283-2289.
    • (2006) J Clin Oncol , vol.24 , pp. 2283-2289
    • Beck, K.E.1    Blansfield, J.A.2    Tran, K.Q.3
  • 9
    • 0043196687 scopus 로고    scopus 로고
    • Suicide genes as safety switches in T lymphocytes
    • Straathof KC, Spencer DM, Sutton RE, et al. Suicide genes as safety switches in T lymphocytes. Cytotherapy. 2003; 5: 227-230.
    • (2003) Cytotherapy , vol.5 , pp. 227-230
    • Straathof, K.C.1    Spencer, D.M.2    Sutton, R.E.3
  • 10
    • 70149114880 scopus 로고    scopus 로고
    • Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
    • Johnson LA, Morgan RA, Dudley ME, et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood. 2009; 114: 535-546.
    • (2009) Blood , vol.114 , pp. 535-546
    • Johnson, L.A.1    Morgan, R.A.2    Dudley, M.E.3
  • 11
    • 65349112495 scopus 로고    scopus 로고
    • Ocular and systemic autoimmunity after successful tumor-infiltrating lymphocyte immunotherapy for recurrent, metastatic melanoma
    • Yeh S, Karne NK, Kerkar SP, et al. Ocular and systemic autoimmunity after successful tumor-infiltrating lymphocyte immunotherapy for recurrent, metastatic melanoma. Ophthalmology. 2009; 116: 981-989.
    • (2009) Ophthalmology , vol.116 , pp. 981-989
    • Yeh, S.1    Karne, N.K.2    Kerkar, S.P.3
  • 12
    • 84870412110 scopus 로고    scopus 로고
    • Audiovestibular dysfunction associated with adoptive cell immunotherapy for melanoma
    • Seaman BJ, Guardiani EA, Brewer CC, et al. Audiovestibular dysfunction associated with adoptive cell immunotherapy for melanoma. Otolaryngol Head Neck Surg. 2012; 147: 744-749.
    • (2012) Otolaryngol Head Neck Surg , vol.147 , pp. 744-749
    • Seaman, B.J.1    Guardiani, E.A.2    Brewer, C.C.3
  • 13
    • 84878605813 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: Clinical evaluation and management of on-target toxicity
    • Lamers CH, Sleijfer S, van Steenbergen S, et al. Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity. Mol Ther. 2013; 21: 904-912.
    • (2013) Mol Ther , vol.21 , pp. 904-912
    • Lamers, C.H.1    Sleijfer, S.2    Van Steenbergen, S.3
  • 14
    • 33646440024 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience
    • Lamers CH, Sleijfer S, Vulto AG, et al. Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. J Clin Oncol. 2006; 24: e20-e22.
    • (2006) J Clin Oncol , vol.24 , pp. e20-e22
    • Lamers, C.H.1    Sleijfer, S.2    Vulto, A.G.3
  • 15
    • 79952187823 scopus 로고    scopus 로고
    • T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
    • ParkhurstMR, Yang JC, Langan RC, et al. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Mol Ther. 2011; 19: 620-626.
    • (2011) Mol Ther , vol.19 , pp. 620-626
    • Parkhurst, M.R.1    Yang, J.C.2    Langan, R.C.3
  • 16
    • 84876005284 scopus 로고    scopus 로고
    • CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
    • Brentjens RJ, DavilaML, Riviere I, et al. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med. 2013; 5: 177ra38.
    • (2013) Sci Transl Med , vol.5 , pp. 177ra38
    • Brentjens, R.J.1    Davilaml Riviere, I.2
  • 17
    • 84863337890 scopus 로고    scopus 로고
    • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
    • Kochenderfer JN, Dudley ME, Feldman SA, et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood. 2012; 119: 2709-2720.
    • (2012) Blood , vol.119 , pp. 2709-2720
    • Kochenderfer, J.N.1    Dudley, M.E.2    Feldman, S.A.3
  • 18
    • 42349088534 scopus 로고    scopus 로고
    • Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system
    • Singh H, Manuri PR, Olivares S, et al. Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system. Cancer Res. 2008; 68: 2961-2971.
    • (2008) Cancer Res , vol.68 , pp. 2961-2971
    • Singh, H.1    Manuri, P.R.2    Olivares, S.3
  • 19
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, et al. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl JMed. 2011; 365: 725-733.
    • (2011) N Engl JMed , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3
  • 20
    • 84923118622 scopus 로고    scopus 로고
    • Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor
    • Kochenderfer JN, Dudley ME, Kassim SH, et al. Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor. J Clin Oncol. 2015; 33: 540-549.
    • (2015) J Clin Oncol , vol.33 , pp. 540-549
    • Kochenderfer, J.N.1    Dudley, M.E.2    Kassim, S.H.3
  • 21
    • 84873991752 scopus 로고    scopus 로고
    • Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
    • Morgan RA, Chinnasamy N, Abate-Daga D, et al. Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. J Immunother. 2013; 36: 133-151.
    • (2013) J Immunother , vol.36 , pp. 133-151
    • Morgan, R.A.1    Chinnasamy, N.2    Abate-Daga, D.3
  • 22
    • 84880730689 scopus 로고    scopus 로고
    • Cardiovascular toxicity and Titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
    • Linette GP, Stadtmauer EA, Maus MV, et al. Cardiovascular toxicity and Titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma. Blood. 2013; 122: 863-871.
    • (2013) Blood , vol.122 , pp. 863-871
    • Linette, G.P.1    Stadtmauer, E.A.2    Maus, M.V.3
  • 23
    • 84883866836 scopus 로고    scopus 로고
    • Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells
    • Cameron BJ, Gerry AB, Dukes J, et al. Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells. Sci Transl Med. 2013; 5: 197ra103.
    • (2013) Sci Transl Med , vol.5 , pp. 197ra103
    • Cameron, B.J.1    Gerry, A.B.2    Dukes, J.3
  • 24
    • 77952236875 scopus 로고    scopus 로고
    • Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy
    • Bendle GM, Linnemann C, Hooijkaas AI, et al. Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy. Nat Med. 2010; 16: 565-570.
    • (2010) Nat Med , vol.16 , pp. 565-570
    • Bendle, G.M.1    Linnemann, C.2    Hooijkaas, A.I.3
  • 25
    • 84964314498 scopus 로고    scopus 로고
    • RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer
    • Bunse M, Bendle GM, Linnemann C, et al. RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer. Mol Ther. 2014; 22: 1983-1991.
    • (2014) Mol Ther , vol.22 , pp. 1983-1991
    • Bunse, M.1    Bendle, G.M.2    Linnemann, C.3
  • 26
    • 84860681545 scopus 로고    scopus 로고
    • Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
    • Provasi E, Genovese P, Lombardo A, et al. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer. Nat Med. 2012; 18: 807-815.
    • (2012) Nat Med , vol.18 , pp. 807-815
    • Provasi, E.1    Genovese, P.2    Lombardo, A.3
  • 27
    • 33947217494 scopus 로고    scopus 로고
    • Facilitating matched pairing and expression of TCR chains introduced into human T cells
    • Kuball J, Dossett ML, Wolfl M, et al. Facilitating matched pairing and expression of TCR chains introduced into human T cells. Blood. 2007; 109: 2331-2338.
    • (2007) Blood , vol.109 , pp. 2331-2338
    • Kuball, J.1    Dossett, M.L.2    Wolfl, M.3
  • 28
    • 79960299888 scopus 로고    scopus 로고
    • Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
    • Rosenberg SA, Yang JC, Sherry RM, et al. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin Cancer Res. 2011; 17: 4550-4557.
    • (2011) Clin Cancer Res , vol.17 , pp. 4550-4557
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3
  • 29
    • 0031420973 scopus 로고    scopus 로고
    • Genomic cloning and localization of CTAG, a gene encoding an autoimmunogenic cancer-testis antigen NY-ESO-1, to human chromosome Xq28
    • Chen YT, Boyer AD, Viars CS, et al. Genomic cloning and localization of CTAG, a gene encoding an autoimmunogenic cancer-testis antigen NY-ESO-1, to human chromosome Xq28. Cytogenet Cell Genet. 1997; 79: 237-240.
    • (1997) Cytogenet Cell Genet , vol.79 , pp. 237-240
    • Chen, Y.T.1    Boyer, A.D.2    Viars, C.S.3
  • 30
    • 84928912377 scopus 로고    scopus 로고
    • A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: Longterm follow-up and correlates with response
    • Robbins PF, Kassim SH, Tran TL, et al. A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: longterm follow-up and correlates with response. Clin Cancer Res. 2015; 21: 1019-1027.
    • (2015) Clin Cancer Res , vol.21 , pp. 1019-1027
    • Robbins, P.F.1    Kassim, S.H.2    Tran, T.L.3
  • 31
    • 84933508708 scopus 로고    scopus 로고
    • Complete regression ofmetastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells
    • Stevanovic S, Draper LM, LanghanMM, et al. Complete regression ofmetastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells. J Clin Oncol. 2015; 33: 1543-1550.
    • (2015) J Clin Oncol , vol.33 , pp. 1543-1550
    • Stevanovic, S.1    Draper, L.M.2    Langhan, M.M.3
  • 32
    • 84880276438 scopus 로고    scopus 로고
    • Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumorreactive T cells
    • Robbins PF, Lu YC, El-Gamil M, et al. Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumorreactive T cells. Nat Med. 2013; 19: 747-752.
    • (2013) Nat Med , vol.19 , pp. 747-752
    • Robbins, P.F.1    Lu, Y.C.2    El-Gamil, M.3
  • 33
    • 84900301377 scopus 로고    scopus 로고
    • + T cells in a patient with epithelial cancer
    • + T cells in a patient with epithelial cancer. Science. 2014; 344: 641-645.
    • (2014) Science , vol.344 , pp. 641-645
    • Tran, E.1    Turcotte, S.2    Gros, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.