Matrix metalloproteinase-12 induces blood-brain barrier damage after focal cerebral ischemia

Stroke

Volumn 46, Issue 12, 2015, Pages 3523-3531

  Chelluboina, Bharath ^a   Klopfenstein, Jeffrey D ^a,c   Pinson, David M ^a   Wang, David Z ^a,c   Vemuganti, Raghu ^b   Veeravalli, Krishna Kumar ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c Illinois Neurological Institute   (United States)

Author keywords

blood brain barrier; degradation; ischemia; matrix metalloproteinase; reperfusion; tight junction; tissue type plasminogen activator

Indexed keywords

CLAUDIN 5; GELATINASE B; MACROPHAGE ELASTASE; NANOPARTICLE; OCCLUDIN; PROTEIN ZO1; SHORT HAIRPIN RNA; TIGHT JUNCTION PROTEIN; TISSUE PLASMINOGEN ACTIVATOR; MATRIX METALLOPEPTIDASE 12, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DAMAGE; BRAIN ISCHEMIA; BRAIN REGION; BRAIN TISSUE; CONTROLLED STUDY; FOCAL CEREBRAL ISCHEMIA; INTERNAL CAROTID ARTERY; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION; UPREGULATION; ANIMAL; BIOSYNTHESIS; BRAIN; ENZYMOLOGY; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; BRAIN ISCHEMIA; MATRIX METALLOPROTEINASE 12; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84948100824     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.115.011031     Document Type: Article

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