메뉴 건너뛰기




Volumn 11, Issue 12, 2015, Pages 695-706

Therapeutic use of human renal progenitor cells for kidney regeneration

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ADULT STEM CELL; CELL DIFFERENTIATION; CELL ISOLATION; EMBRYONIC STEM CELL; FETAL STEM CELL; FETUS; HUMAN; KIDNEY CELL; KIDNEY DISEASE; KIDNEY INJURY; KIDNEY PARENCHYMA; KIDNEY TUBULE CELL; MESENCHYMAL STROMA CELL; MICROENVIRONMENT; MOUSE; PHENOTYPIC PLASTICITY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RENAL STEM CELL; REVIEW; STEM CELL; STEM CELL CULTURE; TISSUE REGENERATION; URINE; ANIMAL; CYTOLOGY; KIDNEY; PHYSIOLOGY; REGENERATION; RENAL INSUFFICIENCY, CHRONIC; STEM CELL TRANSPLANTATION;

EID: 84948086347     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2015.126     Document Type: Review
Times cited : (54)

References (98)
  • 1
    • 84880511470 scopus 로고    scopus 로고
    • Chronic kidney disease: Global dimension and perspectives
    • Jha, V. et al. Chronic kidney disease: global dimension and perspectives. Lancet 382, 260-272 (2013).
    • (2013) Lancet , vol.382 , pp. 260-272
    • Jha, V.1
  • 3
    • 84892760007 scopus 로고    scopus 로고
    • Evidence for a morphologically distinct and functionally robust cell type in the proximal tubules of human kidney
    • Hansson, J. et al. Evidence for a morphologically distinct and functionally robust cell type in the proximal tubules of human kidney. Hum. Pathol. 45, 382-393 (2014).
    • (2014) Hum. Pathol. , vol.45 , pp. 382-393
    • Hansson, J.1
  • 4
    • 53649093784 scopus 로고    scopus 로고
    • Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes
    • Metsuyanim, S. et al. Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes. Stem Cells 26, 1808-1817 (2008).
    • (2008) Stem Cells , vol.26 , pp. 1808-1817
    • Metsuyanim, S.1
  • 5
    • 84903705384 scopus 로고    scopus 로고
    • Acute kidney injury and chronic kidney disease as interconnected syndromes
    • Chawla, L. S., Eggers, P. W., Star, R. A., Kimmel, P. L. Acute kidney injury and chronic kidney disease as interconnected syndromes. N. Engl. J. Med. 371, 58-66 (2014).
    • (2014) N. Engl. J. Med. , vol.371 , pp. 58-66
    • Chawla, L.S.1    Eggers, P.W.2    Star, R.A.3    Kimmel, P.L.4
  • 6
    • 77952946956 scopus 로고    scopus 로고
    • Patterning a complex organ: Branching morphogenesis and nephron segmentation in kidney development
    • Costantini, F., Kopan, R. Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development. Dev. Cell 18, 698-712 (2010).
    • (2010) Dev. Cell , vol.18 , pp. 698-712
    • Costantini, F.1    Kopan, R.2
  • 7
    • 37349080652 scopus 로고    scopus 로고
    • Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia
    • Boyle, S. et al. Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia. Dev. Biol. 313, 234-245 (2008).
    • (2008) Dev. Biol. , vol.313 , pp. 234-245
    • Boyle, S.1
  • 8
    • 48149095359 scopus 로고    scopus 로고
    • Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development
    • Kobayashi, A. et al. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell 3, 169-181 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 169-181
    • Kobayashi, A.1
  • 9
    • 84892453511 scopus 로고    scopus 로고
    • Nephron progenitor cells: Shifting the balance of self-renewal and differentiation
    • Kopan, R., Chen, S., Little, M. Nephron progenitor cells: shifting the balance of self-renewal and differentiation. Curr. Top. Dev. Biol. 107, 293-331 (2014).
    • (2014) Curr. Top. Dev. Biol. , vol.107 , pp. 293-331
    • Kopan, R.1    Chen, S.2    Little, M.3
  • 10
    • 84923950723 scopus 로고    scopus 로고
    • Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor
    • Kanda, S. et al. Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor. J. Am. Soc. Nephrol. 25, 2584-2595 (2014).
    • (2014) J. Am. Soc. Nephrol. , vol.25 , pp. 2584-2595
    • Kanda, S.1
  • 11
    • 0031760440 scopus 로고    scopus 로고
    • Eya1 expression in the developing ear and kidney: Towards the understanding of the pathogenesis of branchio-oto-renal (BOR) syndrome
    • Kalatzis, V., Sahly, I., El-Amraoui, A., Petit, C. Eya1 expression in the developing ear and kidney: towards the understanding of the pathogenesis of branchio-oto-renal (BOR) syndrome. Dev. Dyn. 213, 486-499 (1998).
    • (1998) Dev. Dyn. , vol.213 , pp. 486-499
    • Kalatzis, V.1    Sahly, I.2    El-Amraoui, A.3    Petit, C.4
  • 12
    • 84896288676 scopus 로고    scopus 로고
    • Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis
    • Xu, J., Liu, H., Park, J. S., Lan, Y., Jiang, R. Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis. Development 141, 1442-1452 (2014).
    • (2014) Development , vol.141 , pp. 1442-1452
    • Xu, J.1    Liu, H.2    Park, J.S.3    Lan, Y.4    Jiang, R.5
  • 13
    • 0029590072 scopus 로고
    • Pax-2 controls multiple steps of urogenital development
    • Torres, M., Gómez-Pardo, E., Dressler, G. R., Gruss, P. Pax-2 controls multiple steps of urogenital development. Development 121, 4057-4065 (1995).
    • (1995) Development , vol.121 , pp. 4057-4065
    • Torres, M.1    Gómez-Pardo, E.2    Dressler, G.R.3    Gruss, P.4
  • 14
    • 0027182741 scopus 로고
    • WT-1 is required for early kidney development
    • Kreidberg, J. A. et al. WT-1 is required for early kidney development. Cell 74, 679-691 (1993).
    • (1993) Cell , vol.74 , pp. 679-691
    • Kreidberg, J.A.1
  • 15
    • 84866926354 scopus 로고    scopus 로고
    • Lgr5+ve stem/progenitor cells contribute to nephron formation during kidney development
    • Barker, N. et al. Lgr5+ve stem/progenitor cells contribute to nephron formation during kidney development. Cell Rep. 2, 540-552 (2012).
    • (2012) Cell Rep , vol.2 , pp. 540-552
    • Barker, N.1
  • 16
    • 77952561091 scopus 로고    scopus 로고
    • Notch2 activation in the embryonic kidney depletes nephron progenitors
    • Fujimura, S., Jiang, Q., Kobayashi, C., Nishinakamura, R. Notch2 activation in the embryonic kidney depletes nephron progenitors. J. Am. Soc. Nephrol. 21, 803-810 (2010).
    • (2010) J. Am. Soc. Nephrol. , vol.21 , pp. 803-810
    • Fujimura, S.1    Jiang, Q.2    Kobayashi, C.3    Nishinakamura, R.4
  • 17
    • 33745728174 scopus 로고    scopus 로고
    • Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney
    • Dekel, B. et al. Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney. Cancer Res. 66, 6040-6049 (2006).
    • (2006) Cancer Res , vol.66 , pp. 6040-6049
    • Dekel, B.1
  • 18
    • 69249219272 scopus 로고    scopus 로고
    • Expression of stem cell markers in the human fetal kidney
    • Metsuyanim, S. et al. Expression of stem cell markers in the human fetal kidney. PLoS ONE 4, e6709 (2009).
    • (2009) PLoS ONE , vol.4 , pp. e6709
    • Metsuyanim, S.1
  • 19
    • 84884938538 scopus 로고    scopus 로고
    • Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease
    • Harari-Steinberg, O. et al. Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease. EMBO Mol. Med. 5, 1556-1568 (2013).
    • (2013) EMBO Mol. Med. , vol.5 , pp. 1556-1568
    • Harari-Steinberg, O.1
  • 20
    • 78651318060 scopus 로고    scopus 로고
    • Expression of stem cell marker CD133 in fetal and adult human kidneys and pauci-immune crescentic glomerulonephritis
    • Kim, K. et al. Expression of stem cell marker CD133 in fetal and adult human kidneys and pauci-immune crescentic glomerulonephritis. Histol. Histopathol. 26, 223-232 (2011).
    • (2011) Histol. Histopathol. , vol.26 , pp. 223-232
    • Kim, K.1
  • 21
    • 36849090211 scopus 로고    scopus 로고
    • Regenerative potential of embryonic renal multipotent progenitors in acute renal failure
    • Lazzeri, E. et al. Regenerative potential of embryonic renal multipotent progenitors in acute renal failure. J. Am. Soc. Nephrol. 18, 3128-3138 (2007).
    • (2007) J. Am. Soc. Nephrol. , vol.18 , pp. 3128-3138
    • Lazzeri, E.1
  • 22
  • 23
    • 34848815660 scopus 로고    scopus 로고
    • Cessation of renal morphogenesis in mice
    • Hartman, H. A., Lai, H. L., Patterson, L. T. Cessation of renal morphogenesis in mice. Dev. Biol. 310, 379-387 (2007).
    • (2007) Dev. Biol. , vol.310 , pp. 379-387
    • Hartman, H.A.1    Lai, H.L.2    Patterson, L.T.3
  • 24
    • 0036893384 scopus 로고    scopus 로고
    • Involvement of Pax-2 in the action of activin A on tubular cell regeneration
    • Maeshima, A., Maeshima, K., Nojima, Y., Kojima, I. Involvement of Pax-2 in the action of activin A on tubular cell regeneration. J. Am. Soc. Nephrol. 13, 2850-2859 (2002).
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 2850-2859
    • Maeshima, A.1    Maeshima, K.2    Nojima, Y.3    Kojima, I.4
  • 25
    • 0013979580 scopus 로고
    • The normal urinary excretion rates of renal tubular cells, leucocytes and red blood cells
    • Prescott, L. F. The normal urinary excretion rates of renal tubular cells, leucocytes and red blood cells. Clin. Sci. 31, 425-435 (1966).
    • (1966) Clin. Sci. , vol.31 , pp. 425-435
    • Prescott, L.F.1
  • 26
    • 39749172401 scopus 로고    scopus 로고
    • Intrinsic epithelial cells repair the kidney after injury
    • Humphreys, B. D. et al. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell 6, 284-291 (2008).
    • (2008) Cell Stem Cell , vol.6 , pp. 284-291
    • Humphreys, B.D.1
  • 28
    • 84893408316 scopus 로고    scopus 로고
    • Origin of regenerating tubular cells after acute kidney injury
    • Berger, K. et al. Origin of regenerating tubular cells after acute kidney injury. Proc. Natl Acad. Sci. USA 111, 1533-1538 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 1533-1538
    • Berger, K.1
  • 29
    • 84907996792 scopus 로고    scopus 로고
    • Mechanisms of epithelial repair and regeneration after acute kidney injury
    • Berger, K., Moeller, M. J. Mechanisms of epithelial repair and regeneration after acute kidney injury. Semin. Nephrol. 34, 394-403 (2014).
    • (2014) Semin. Nephrol. , vol.34 , pp. 394-403
    • Berger, K.1    Moeller, M.J.2
  • 30
    • 59949092665 scopus 로고    scopus 로고
    • Recruitment of podocytes from glomerular parietal epithelial cells
    • Appel, D. et al. Recruitment of podocytes from glomerular parietal epithelial cells. J. Am. Soc. Nephrol. 20, 333-343 (2009).
    • (2009) J. Am. Soc. Nephrol. , vol.20 , pp. 333-343
    • Appel, D.1
  • 31
    • 84908187598 scopus 로고    scopus 로고
    • The regenerative potential of parietal epithelial cells in adult mice
    • Berger, K. et al. The regenerative potential of parietal epithelial cells in adult mice. J. Am. Soc. Nephrol. 25, 693-705 (2014).
    • (2014) J. Am. Soc. Nephrol. , vol.25 , pp. 693-705
    • Berger, K.1
  • 32
    • 0345530117 scopus 로고    scopus 로고
    • Identification of renal progenitor-like tubular cells that participate in the regeneration processes of the kidney
    • Maeshima, A., Yamashita, S., Nojima, Y. Identification of renal progenitor-like tubular cells that participate in the regeneration processes of the kidney. J. Am. Soc. Nephrol. 14, 3138-3146 (2003).
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 3138-3146
    • Maeshima, A.1    Yamashita, S.2    Nojima, Y.3
  • 35
    • 84883434600 scopus 로고    scopus 로고
    • C-Kit+ cells isolated from developing kidneys are a novel population of stem cells with regenerative potential
    • Rangel, E. B. et al. C-Kit+ cells isolated from developing kidneys are a novel population of stem cells with regenerative potential. Stem Cells 31, 1644-1656 (2013).
    • (2013) Stem Cells , vol.31 , pp. 1644-1656
    • Rangel, E.B.1
  • 36
    • 0031453534 scopus 로고    scopus 로고
    • AC133, a novel marker for human hematopoietic stem and progenitor cells
    • Yin, A. H. et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 90, 5002-5012 (1997).
    • (1997) Blood , vol.90 , pp. 5002-5012
    • Yin, A.H.1
  • 37
    • 76549120193 scopus 로고    scopus 로고
    • The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation
    • Kemper, K. et al. The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation. Cancer Res. 70, 719-729 (2010).
    • (2010) Cancer Res , vol.70 , pp. 719-729
    • Kemper, K.1
  • 38
    • 33748051419 scopus 로고    scopus 로고
    • J Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys
    • Sagrinati, C. et al. J. Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. J. Am. Soc. Nephrol. 17, 2443-2456 (2006).
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 2443-2456
    • Sagrinati, C.1
  • 39
    • 83455198200 scopus 로고    scopus 로고
    • Hypoxia modulates the undifferentiated phenotype of human renal inner medullary CD133+ progenitors through Oct4/miR-145 balance
    • Bussolati, B. et al. Hypoxia modulates the undifferentiated phenotype of human renal inner medullary CD133+ progenitors through Oct4/miR-145 balance. Am. J. Physiol. Renal Physiol. 302, F116-F128 (2012).
    • (2012) Am. J. Physiol. Renal Physiol. , vol.302 , pp. F116-F128
    • Bussolati, B.1
  • 40
    • 84875037125 scopus 로고    scopus 로고
    • Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration
    • Smeets, B. et al. Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration. J. Pathol. 229, 645-659 (2013).
    • (2013) J. Pathol. , vol.229 , pp. 645-659
    • Smeets, B.1
  • 41
    • 80052261111 scopus 로고    scopus 로고
    • Adult human CD133/1+ kidney cells isolated from papilla integrate into developing kidney tubules
    • Ward, H. H. et al. Adult human CD133/1+ kidney cells isolated from papilla integrate into developing kidney tubules. Biochim. Biophys. Acta. 1812, 1344-1357 (2011).
    • (2011) Biochim. Biophys. Acta. , vol.1812 , pp. 1344-1357
    • Ward, H.H.1
  • 42
    • 79951849286 scopus 로고    scopus 로고
    • Isolation and characterization of progenitor-like cells from human renal proximal tubules
    • Lindgren, D. et al. Isolation and characterization of progenitor-like cells from human renal proximal tubules. Am. J. Pathol. 178, 828-837 (2011).
    • (2011) Am. J. Pathol. , vol.178 , pp. 828-837
    • Lindgren, D.1
  • 43
    • 59949101434 scopus 로고    scopus 로고
    • Regeneration of glomerular podocytes by human renal progenitors
    • Ronconi, E. et al. Regeneration of glomerular podocytes by human renal progenitors. J. Am. Soc. Nephrol. 20, 322-332 (2009).
    • (2009) J. Am. Soc. Nephrol. , vol.20 , pp. 322-332
    • Ronconi, E.1
  • 44
    • 84864365555 scopus 로고    scopus 로고
    • Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury
    • Angelotti, M. L. et al. Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury. Stem Cells 30, 1714-1725 (2012).
    • (2012) Stem Cells , vol.30 , pp. 1714-1725
    • Angelotti, M.L.1
  • 45
    • 80053214612 scopus 로고    scopus 로고
    • The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells
    • Bourseau-Guilmain, E., Griveau, A., Benoit, J. P., Garcion, E. The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells. PLoS ONE 6, e25515 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e25515
    • Bourseau-Guilmain, E.1    Griveau, A.2    Benoit, J.P.3    Garcion, E.4
  • 46
    • 56349113871 scopus 로고    scopus 로고
    • CD133 is a marker of bioenergetic stress in human glioma
    • Griguer, C. E. et al. CD133 is a marker of bioenergetic stress in human glioma. PLoS ONE 3, e3655 (2008).
    • (2008) PLoS ONE , vol.3 , pp. e3655
    • Griguer, C.E.1
  • 47
    • 42549151568 scopus 로고    scopus 로고
    • Increase of proliferating renal progenitor cells in acute tubular necrosis underlying delayed graft function
    • Loverre, A. et al. Increase of proliferating renal progenitor cells in acute tubular necrosis underlying delayed graft function. Transplantation 85, 1112-1119 (2008).
    • (2008) Transplantation , vol.85 , pp. 1112-1119
    • Loverre, A.1
  • 48
    • 79960429087 scopus 로고    scopus 로고
    • Proliferative capacity of stem/progenitor-like cells in the kidney may associate with the outcome of patients with acute tubular necrosis
    • Ye, Y. et al. Proliferative capacity of stem/progenitor-like cells in the kidney may associate with the outcome of patients with acute tubular necrosis. Hum. Pathol. 42, 1132-1141 (2011).
    • (2011) Hum. Pathol. , vol.42 , pp. 1132-1141
    • Ye, Y.1
  • 49
    • 72049121911 scopus 로고    scopus 로고
    • Renal progenitor cells contribute to hyperplastic lesions of podocytopathies and crescentic glomerulonephritis
    • Smeets, B. et al. Renal progenitor cells contribute to hyperplastic lesions of podocytopathies and crescentic glomerulonephritis. J. Am. Soc. Nephrol. 20, 2593-2603 (2009).
    • (2009) J. Am. Soc. Nephrol. , vol.20 , pp. 2593-2603
    • Smeets, B.1
  • 50
    • 77952174830 scopus 로고    scopus 로고
    • Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
    • Yang, L., Besschetnova, T. Y., Brooks, C. R., Shah, J. V., Bonventre, J. V. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat. Med. 16, 535-543 (2010).
    • (2010) Nat. Med. , vol.16 , pp. 535-543
    • Yang, L.1    Besschetnova, T.Y.2    Brooks, C.R.3    Shah, J.V.4    Bonventre, J.V.5
  • 51
    • 33845236217 scopus 로고    scopus 로고
    • Isolation and characterization of nontubular sca-1+lin-multipotent stem/progenitor cells from adult mouse kidney
    • Dekel, B. et al. Isolation and characterization of nontubular sca-1+lin-multipotent stem/progenitor cells from adult mouse kidney. J. Am. Soc. Nephrol. 17, 3300-3314 (2006).
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 3300-3314
    • Dekel, B.1
  • 52
    • 79960898393 scopus 로고    scopus 로고
    • Cystogenic potential of CD133+ progenitor cells of human polycystic kidneys
    • Carvalhosa, R. et al. Cystogenic potential of CD133+ progenitor cells of human polycystic kidneys. J. Pathol. 225, 129-141 (2011).
    • (2011) J. Pathol. , vol.225 , pp. 129-141
    • Carvalhosa, R.1
  • 53
    • 84887619426 scopus 로고    scopus 로고
    • Dedifferentiation of committed epithelial cells into stem cells in vivo
    • Tata, P. R. et al. Dedifferentiation of committed epithelial cells into stem cells in vivo. Nature 503, 218-223 (2013).
    • (2013) Nature , vol.503 , pp. 218-223
    • Tata, P.R.1
  • 54
    • 84898405994 scopus 로고    scopus 로고
    • The murine long-term multi-lineage renewal marrow stem cell is a cycling cell
    • Goldberg, L. R. et al. The murine long-term multi-lineage renewal marrow stem cell is a cycling cell. Leukemia 28, 813-822 (2014).
    • (2014) Leukemia , vol.28 , pp. 813-822
    • Goldberg, L.R.1
  • 55
    • 66349132211 scopus 로고    scopus 로고
    • Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis
    • Sangiorgi, E., Capecchi, M. R. Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis. Proc. Natl Acad. Sci. USA 106, 7101-7106 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 7101-7106
    • Sangiorgi, E.1    Capecchi, M.R.2
  • 56
    • 84862891089 scopus 로고    scopus 로고
    • Progenitor/stem cell fate determination: Interactive dynamics of cell cycle and microvesicles
    • Aliotta, J. M. et al. Progenitor/stem cell fate determination: interactive dynamics of cell cycle and microvesicles. Stem Cells Dev. 21, 1627-1638 (2012).
    • (2012) Stem Cells Dev. , vol.21 , pp. 1627-1638
    • Aliotta, J.M.1
  • 57
    • 27744571294 scopus 로고    scopus 로고
    • Establishment and characterization of renal progenitor like cells from S3 segment of nephron in rat adult kidney
    • Kitamura, S. et al. Establishment and characterization of renal progenitor like cells from S3 segment of nephron in rat adult kidney. FASEB J. 19, 1789-1797 (2005).
    • (2005) FASEB J. , vol.19 , pp. 1789-1797
    • Kitamura, S.1
  • 58
    • 33645455730 scopus 로고    scopus 로고
    • Adult kidney tubular cell population showing phenotypic plasticity, tubulogenic capacity, and integration capability into developing kidney
    • Maeshima, A., Sakurai, H., Nigam, S. K. Adult kidney tubular cell population showing phenotypic plasticity, tubulogenic capacity, and integration capability into developing kidney. J. Am. Soc. Nephrol. 17, 188-198 (2006).
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 188-198
    • Maeshima, A.1    Sakurai, H.2    Nigam, S.K.3
  • 59
    • 33750702156 scopus 로고    scopus 로고
    • Isolation and characterization of kidney-derived stem cells
    • Gupta, S. et al. Isolation and characterization of kidney-derived stem cells. J. Am. Soc. Nephrol. 17, 3028-3040 (2006).
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 3028-3040
    • Gupta, S.1
  • 60
    • 33745830532 scopus 로고    scopus 로고
    • Kidney side population reveals multilineage potential and renal functional capacity but also cellular heterogeneity
    • Challen, G. A., Bertoncello, I., Deane, J. A., Ricardo, S. D., Little, M. H. Kidney side population reveals multilineage potential and renal functional capacity but also cellular heterogeneity. J. Am. Soc. Nephrol. 17, 1896-1912 (2006).
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 1896-1912
    • Challen, G.A.1    Bertoncello, I.2    Deane, J.A.3    Ricardo, S.D.4    Little, M.H.5
  • 61
    • 13244251415 scopus 로고    scopus 로고
    • Isolation of renal progenitor cells from adult human kidney
    • Bussolati, B. et al. Isolation of renal progenitor cells from adult human kidney. Am. J. Pathol. 166, 545-555 (2005).
    • (2005) Am. J. Pathol. , vol.166 , pp. 545-555
    • Bussolati, B.1
  • 62
    • 76149131374 scopus 로고    scopus 로고
    • TLR2 plays a role in the activation of human resident renal stem/progenitor cells
    • Sallustio, F. et al. TLR2 plays a role in the activation of human resident renal stem/progenitor cells. FASEB J. 24, 514-525 (2010).
    • (2010) FASEB J , vol.24 , pp. 514-525
    • Sallustio, F.1
  • 63
    • 84881115491 scopus 로고    scopus 로고
    • Renal CD133+/CD73+ progenitors produce erythropoietin under hypoxia and prolyl hydroxylase inhibition
    • Bussolati, B. et al. Renal CD133+/CD73+ progenitors produce erythropoietin under hypoxia and prolyl hydroxylase inhibition. J. Am. Soc. Nephrol. 24, 1234-1241 (2013).
    • (2013) J. Am. Soc. Nephrol. , vol.24 , pp. 1234-1241
    • Bussolati, B.1
  • 64
    • 84886665688 scopus 로고    scopus 로고
    • Reactivation of NCAM1 defines a subpopulation of human adult kidney epithelial cells with clonogenic and stem/progenitor properties
    • Buzhor, E. et al. Reactivation of NCAM1 defines a subpopulation of human adult kidney epithelial cells with clonogenic and stem/progenitor properties. Am. J. Pathol. 183, 1621-1633 (2013).
    • (2013) Am. J. Pathol. , vol.183 , pp. 1621-1633
    • Buzhor, E.1
  • 65
    • 84926629528 scopus 로고    scopus 로고
    • Human urine-derived renal progenitors for personalized modeling of genetic kidney disorders
    • Lazzeri, E. et al. Human urine-derived renal progenitors for personalized modeling of genetic kidney disorders. J. Am. Soc. Nephrol. http://dx.doi.org/10.1681/ASN.2014010057.
    • J. Am. Soc. Nephrol.
    • Lazzeri, E.1
  • 66
    • 84883641029 scopus 로고    scopus 로고
    • PKHhigh cells within clonal human nephrospheres provide a purified adult renal stem cell population
    • Bombelli, S. et al. PKHhigh cells within clonal human nephrospheres provide a purified adult renal stem cell population. Stem Cell Res. 11, 1163-1177 (2013).
    • (2013) Stem Cell Res , vol.11 , pp. 1163-1177
    • Bombelli, S.1
  • 67
    • 20444386913 scopus 로고    scopus 로고
    • Expression of NCAM recapitulates tubulogenic development in kidneys recovering from acute ischemia
    • Abbate, M., Brown, D., Bonventre, J. V. Expression of NCAM recapitulates tubulogenic development in kidneys recovering from acute ischemia. Am. J. Physiol. 277, F454-F463 (1999).
    • (1999) Am. J. Physiol. , vol.277 , pp. F454-F463
    • Abbate, M.1    Brown, D.2    Bonventre, J.V.3
  • 68
    • 53249151581 scopus 로고    scopus 로고
    • Urine derived cells are a potential source for urological tissue reconstruction
    • Zhang, Y. et al. Urine derived cells are a potential source for urological tissue reconstruction. J. Urol. 180, 2226-2233 (2008).
    • (2008) J. Urol. , vol.180 , pp. 2226-2233
    • Zhang, Y.1
  • 69
    • 84880935018 scopus 로고    scopus 로고
    • Multipotential differentiation of human urine-derived stem cells: Potential for therapeutic applications in urology
    • Bharadwaj, S. et al. Multipotential differentiation of human urine-derived stem cells: potential for therapeutic applications in urology. Stem Cells 31, 1840-1856 (2013).
    • (2013) Stem Cells , vol.31 , pp. 1840-1856
    • Bharadwaj, S.1
  • 70
    • 76049087564 scopus 로고    scopus 로고
    • Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications
    • Da Sacco, S. et al. Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications. J. Urol. 183, 1193-1200 (2010).
    • (2010) J. Urol. , vol.183 , pp. 1193-1200
    • Da Sacco, S.1
  • 71
    • 50849139576 scopus 로고    scopus 로고
    • A perivascular origin for mesenchymal stem cells in multiple human organs
    • Crisan, M. et al. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 3, 301-313 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 301-313
    • Crisan, M.1
  • 72
    • 84881097501 scopus 로고    scopus 로고
    • Adult renal mesenchymal stem cell-like cells contribute to juxtaglomerular cell recruitment
    • Wang, H. et al. Adult renal mesenchymal stem cell-like cells contribute to juxtaglomerular cell recruitment. J. Am. Soc. Nephrol. 24, 1263-1273 (2013).
    • (2013) J. Am. Soc. Nephrol. , vol.24 , pp. 1263-1273
    • Wang, H.1
  • 73
    • 84924113415 scopus 로고    scopus 로고
    • Collecting duct-derived cells display mesenchymal stem cell properties and retain selective in vitro and in vivo epithelial capacity
    • Li, J. et al. Collecting duct-derived cells display mesenchymal stem cell properties and retain selective in vitro and in vivo epithelial capacity. J. Am. Soc. Nephrol. 26, 81-94 (2015).
    • (2015) J. Am. Soc. Nephrol. , vol.26 , pp. 81-94
    • Li, J.1
  • 74
    • 84861576643 scopus 로고    scopus 로고
    • Comprehensive transcriptome and immunophenotype analysis of renal and cardiac MSC-like populations supports strong congruence with bone marrow MSC despite maintenance of distinct identities
    • Pelekanos, R. A. et al. Comprehensive transcriptome and immunophenotype analysis of renal and cardiac MSC-like populations supports strong congruence with bone marrow MSC despite maintenance of distinct identities. Stem Cell Res. 8, 58-73 (2012).
    • (2012) Stem Cell Res , vol.8 , pp. 58-73
    • Pelekanos, R.A.1
  • 75
    • 67651097686 scopus 로고    scopus 로고
    • Isolation and characterization of resident mesenchymal stem cells in human glomeruli
    • Bruno, S. et al. Isolation and characterization of resident mesenchymal stem cells in human glomeruli. Stem Cells Dev. 18, 867-880 (2009).
    • (2009) Stem Cells Dev , vol.18 , pp. 867-880
    • Bruno, S.1
  • 76
    • 84896739916 scopus 로고    scopus 로고
    • Controversies on the origin of proliferating epithelial cells after kidney injury
    • Kusaba, T., Humphreys, B. D. Controversies on the origin of proliferating epithelial cells after kidney injury. Pediatr. Nephrol. 29, 673-679 (2014).
    • (2014) Pediatr. Nephrol. , vol.29 , pp. 673-679
    • Kusaba, T.1    Humphreys, B.D.2
  • 77
    • 0028273536 scopus 로고
    • Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells
    • Witzgall, R., Brown, D., Schwarz, C., Bonventre, J. V. Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J. Clin. Invest. 93, 2175-2188 (1994).
    • (1994) J. Clin. Invest. , vol.93 , pp. 2175-2188
    • Witzgall, R.1    Brown, D.2    Schwarz, C.3    Bonventre, J.V.4
  • 78
    • 84879912080 scopus 로고    scopus 로고
    • MiR-1915 and miR-1225-5p regulate the expression of CD133 PAX2 and TLR2 in adult renal progenitor cells
    • Sallustio, F. et al. miR-1915 and miR-1225-5p regulate the expression of CD133, PAX2 and TLR2 in adult renal progenitor cells. PLoS ONE 8, e68296 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e68296
    • Sallustio, F.1
  • 79
    • 84898669447 scopus 로고    scopus 로고
    • Efficient and rapid induction of human iPSCs/ESCs into nephrogenic intermediate mesoderm using small molecule-based differentiation methods
    • Araoka, T. et al. Efficient and rapid induction of human iPSCs/ESCs into nephrogenic intermediate mesoderm using small molecule-based differentiation methods. PLoS ONE 9, e84881 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e84881
    • Araoka, T.1
  • 80
    • 84906088790 scopus 로고    scopus 로고
    • Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers
    • Lam, A. Q. et al. Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers. J. Am. Soc. Nephrol. 25, 1211-1225 (2014).
    • (2014) J. Am. Soc. Nephrol. , vol.25 , pp. 1211-1225
    • Lam, A.Q.1
  • 81
    • 84891737192 scopus 로고    scopus 로고
    • Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells
    • Taguchi, A. et al. Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. Cell Stem Cell 14, 53-67 (2014).
    • (2014) Cell Stem Cell , vol.14 , pp. 53-67
    • Taguchi, A.1
  • 82
    • 84891298711 scopus 로고    scopus 로고
    • Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney
    • Takasato, M. et al. Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney. Nat. Cell Biol. 16, 118-126 (2014).
    • (2014) Nat. Cell Biol. , vol.16 , pp. 118-126
    • Takasato, M.1
  • 83
    • 84884299771 scopus 로고    scopus 로고
    • Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors
    • Hendry, C. E. et al. Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors. J. Am. Soc. Nephrol. 24, 1424-1434 (2013).
    • (2013) J. Am. Soc. Nephrol. , vol.24 , pp. 1424-1434
    • Hendry, C.E.1
  • 84
    • 79551683930 scopus 로고    scopus 로고
    • Identification of adult nephron progenitors capable of kidney regeneration in zebrafish
    • Diep, C. Q. et al. Identification of adult nephron progenitors capable of kidney regeneration in zebrafish. Nature 470, 95-100 (2011).
    • (2011) Nature , vol.470 , pp. 95-100
    • Diep, C.Q.1
  • 85
    • 84924709458 scopus 로고    scopus 로고
    • Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury
    • Imberti, B. et al. Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury. Sci. Rep. 5, 8826 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 8826
    • Imberti, B.1
  • 86
    • 42249088282 scopus 로고    scopus 로고
    • Amelioration of cisplatin-induced acute renal injury by renal progenitor-like cells derived from the adult rat kidney
    • Kinomura, M. et al. Amelioration of cisplatin-induced acute renal injury by renal progenitor-like cells derived from the adult rat kidney. Cell Transplant. 17, 143-158 (2008).
    • (2008) Cell Transplant , vol.17 , pp. 143-158
    • Kinomura, M.1
  • 87
    • 85003013668 scopus 로고    scopus 로고
    • Protective effect and localization by optical imaging of human renal CD133+ progenitor cells in an acute kidney injury model
    • Grange, C. et al. Protective effect and localization by optical imaging of human renal CD133+ progenitor cells in an acute kidney injury model. Physiol. Rep. 2, e12009 (2004).
    • (2004) Physiol. Rep. , vol.2 , pp. e12009
    • Grange, C.1
  • 88
    • 84893480332 scopus 로고    scopus 로고
    • Renal cells from spermatogonial germline stem cells protect against kidney injury
    • De Chiara, L. et al. Renal cells from spermatogonial germline stem cells protect against kidney injury. J. Am. Soc. Nephrol. 25, 316-328 (2014).
    • (2014) J. Am. Soc. Nephrol. , vol.25 , pp. 316-328
    • De Chiara, L.1
  • 89
    • 65649089130 scopus 로고    scopus 로고
    • Mesenchymal stem cell-derived microvesicles protect against acute tubular injury
    • Bruno, S. et al. Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J. Am. Soc. Nephrol. 20, 1053-1067 (2009).
    • (2009) J. Am. Soc. Nephrol. , vol.20 , pp. 1053-1067
    • Bruno, S.1
  • 90
    • 84874258391 scopus 로고    scopus 로고
    • Interleukin-15 is a major regulator of the cell-microenvironment interactions in human renal homeostasis
    • Giron-Michel, J. et al. Interleukin-15 is a major regulator of the cell-microenvironment interactions in human renal homeostasis. Cytokine Growth Factor Rev. 24, 13-22 (2013).
    • (2013) Cytokine Growth Factor Rev , vol.24 , pp. 13-22
    • Giron-Michel, J.1
  • 91
    • 84874647240 scopus 로고    scopus 로고
    • Human renal stem/progenitor cells repair tubular epithelial cell injury through TLR2-driven inhibin-A and microvesicle-shuttled decorin
    • Sallustio, F. et al. Human renal stem/progenitor cells repair tubular epithelial cell injury through TLR2-driven inhibin-A and microvesicle-shuttled decorin. Kidney Int. 83, 392-403 (2013).
    • (2013) Kidney Int , vol.83 , pp. 392-403
    • Sallustio, F.1
  • 92
    • 51849154952 scopus 로고    scopus 로고
    • Kidney-derived mesenchymal stem cells contribute to vasculogenesis, angiogenesis and endothelial repair
    • Chen, J. et al. Kidney-derived mesenchymal stem cells contribute to vasculogenesis, angiogenesis and endothelial repair. Kidney Int. 74, 879-889 (2008).
    • (2008) Kidney Int , vol.74 , pp. 879-889
    • Chen, J.1
  • 93
    • 84895140744 scopus 로고    scopus 로고
    • Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury
    • Choi, H. Y. et al. Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury. PLoS ONE 9, e87853 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e87853
    • Choi, H.Y.1
  • 94
    • 84875195963 scopus 로고    scopus 로고
    • Efficiency of endovenous versus arterial administration of mesenchymal stem cells for ischemia-reperfusion-induced renal dysfunction in rats
    • Zhuo, W. et al. Efficiency of endovenous versus arterial administration of mesenchymal stem cells for ischemia-reperfusion-induced renal dysfunction in rats. Transplant. Proc. 45, 503-510 (2013).
    • (2013) Transplant. Proc. , vol.45 , pp. 503-510
    • Zhuo, W.1
  • 95
    • 84872116231 scopus 로고    scopus 로고
    • Cell therapy with human renal cell cultures containing erythropoietin-positive cells improves chronic kidney injury
    • Yamaleyeva, L. M. et al. Cell therapy with human renal cell cultures containing erythropoietin-positive cells improves chronic kidney injury. Stem Cells Transl. Med. 1, 373-383 (2012).
    • (2012) Stem Cells Transl. Med. , vol.1 , pp. 373-383
    • Yamaleyeva, L.M.1
  • 96
    • 78349240650 scopus 로고    scopus 로고
    • Tubular cell-enriched subpopulation of primary renal cells improves survival and augments kidney function in rodent model of chronic kidney disease
    • Kelley, R. et al. Tubular cell-enriched subpopulation of primary renal cells improves survival and augments kidney function in rodent model of chronic kidney disease. Am. J. Physiol. Renal Physiol. 299, F1026-F1039 (2010).
    • (2010) Am. J. Physiol. Renal Physiol. , vol.299 , pp. F1026-F1039
    • Kelley, R.1
  • 97
    • 84877713628 scopus 로고    scopus 로고
    • A population of selected renal cells augments renal function and extends survival in the ZSF1 model of progressive diabetic nephropathy
    • Kelley, R. et al. A population of selected renal cells augments renal function and extends survival in the ZSF1 model of progressive diabetic nephropathy. Cell Transplant. 22, 1023-1039 (2013).
    • (2013) Cell Transplant , vol.22 , pp. 1023-1039
    • Kelley, R.1
  • 98
    • 84866920816 scopus 로고    scopus 로고
    • Molecular characterization of the regenerative response induced by intrarenal transplantation of selected renal cells in a rodent model of chronic kidney disease
    • Genheimer, C. W. et al. Molecular characterization of the regenerative response induced by intrarenal transplantation of selected renal cells in a rodent model of chronic kidney disease. Cells Tissues Organs 196, 374-384 (2012).
    • (2012) Cells Tissues Organs , vol.196 , pp. 374-384
    • Genheimer, C.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.