Harnessing the potential of LPMO-containing cellulase cocktails poses new demands on processing conditions

Biotechnology for Biofuels

Volumn 8, Issue 1, 2015, Pages

  Müller, Gerdt ^a   Várnai, Anikó ^a   Johansen, Katja Salomon ^b,c   Eijsink, Vincent G H ^a   Horn, Svein Jarle ^a  

^a NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^b NOVOZYMES A S   (Denmark)

^c CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

Author keywords

AA9; Bioeconomy; Biofuel; Biorefinery; Cellulase; GH61; Lignin

Indexed keywords

BIOFUELS; CELLULOSE; ENZYME ACTIVITY; ENZYMES; LIGNIN; SACCHARIFICATION; SUGARS;

AA9; BIOECONOMY; BIOREFINERIES; CELLULASE; GH61;

MOLECULAR OXYGEN;

BIOFUEL; BIOMASS; CATALYSIS; ENZYME; LIGNIN; PROCESSING;

EID: 84947967113     PISSN: 17546834     EISSN: None     Source Type: Journal    
DOI: 10.1186/s13068-015-0376-y     Document Type: Article

References (34)

1. Merino S, Cherry J. Progress and challenges in enzyme development for biomass utilization. Adv Biochem Eng Biotechnol. 2007;108:95-120.
2. Vaaje-Kolstad G, Westereng B, Horn SJ, Liu ZL, Zhai H, Sorlie M, et al. An oxidative enzyme boosting the enzymatic conversion of recalcitrant polysaccharides. Science. 2010;330(6001):219-22. doi: 10.1126/science.1192231.
3. Quinlan RJ, Sweeney MD, Lo Leggio L, Otten H, Poulsen JCN, Johansen KS, et al. Insights into the oxidative degradation of cellulose by a copper metalloenzyme that exploits biomass components. Proc Natl Acad Sci USA. 2011;108(37):15079-84. doi: 10.1073/pnas.1105776108.
4. Horn SJ, Vaaje-Kolstad G, Westereng B, Eijsink VGH. Novel enzymes for the degradation of cellulose. Biotechnol Biofuels. 2012;5:45. doi: 10.1186/1754-6834-5-45.
5. Phillips CM, Beeson WT, Cate JH, Marletta MA. Cellobiose dehydrogenase and a copper-dependent polysaccharide monooxygenase potentiate cellulose degradation by Neurospora crassa. ACS Chem Biol. 2011;6(12):1399-406. doi: 10.1021/cb200351y.
6. Forsberg Z, Vaaje-Kolstad G, Westereng B, Bunæs AC, Stenstrøm Y, MacKenzie A, et al. Cleavage of cellulose by a CBM33 protein. Protein Sci. 2011;20(9):1479-83. doi: 10.1002/pro.689.
7. Harris PV, Welner D, McFarland KC, Re E, Poulsen JCN, Brown K, et al. Stimulation of lignocellulosic biomass hydrolysis by proteins of glycoside hydrolase family 61: Structure and function of a large, enigmatic family. Biochemistry. 2010;49(15):3305-16. doi: 10.1021/bi100009p.
8. Hu J, Arantes V, Pribowo A, Gourlay K, Saddler JN. Substrate factors that influence the synergistic interaction of AA9 and cellulases during the enzymatic hydrolysis of biomass. Energy Environ Sci. 2014;7(7):2308-15.
9. Cannella D, Hsieh CW, Felby C, Jorgensen H. Production and effect of aldonic acids during enzymatic hydrolysis of lignocellulose at high dry matter content. Biotechnol Biofuels. 2012;5(1):26.
10. Harris PV, Xu F, Kreel NE, Kang C, Fukuyama S. New enzyme insights drive advances in commercial ethanol production. Curr Opin Chem Biol. 2014;19:162-70. doi: 10.1016/j.cbpa.2014.02.015.
11. Westereng B, Ishida T, Vaaje-Kolstad G, Wu M, Eijsink VGH, Igarashi K, et al. The putative endoglucanase PcGH61D from Phanerochaete chrysosporium is a metal-dependent oxidative enzyme that cleaves cellulose. PLoS One. 2011;6(11):e27807. doi: 10.1371/journal.pone.0027807.
12. Forsberg Z, Røhr ÅK, Mekasha S, Andersson KK, Eijsink VG, Vaaje-Kolstad G, et al. Comparative study of two chitin-active and two cellulose-active AA10-type lytic polysaccharide monooxygenases. Biochemistry. 2014;53(10):1647-56.
13. Hemsworth GR, Henrissat B, Davies GJ, Walton PH. Discovery and characterization of a new family of lytic polysaccharide monooxygenases. Nat Chem Biol. 2014;10(2):122-6. doi: 10.1038/nchembio.1417.
14. Isaksen T, Westereng B, Aachmann FL, Agger JW, Kracher D, Kittl R, et al. A C4-oxidizing lytic polysaccharide monooxygenase cleaving both cellulose and cello-oligosaccharides. J Biol Chem. 2014;289(5):2632-42. doi: 10.1074/jbc.M113.530196.
15. Agger JW, Isaksen T, Várnai A, Vidal-Melgosa S, Willats WG, Ludwig R, et al. Discovery of LPMO activity on hemicelluloses shows the importance of oxidative processes in plant cell wall degradation. Proc Natl Acad Sci. 2014;111(17):6287-92.
16. Vu VV, Beeson WT, Span EA, Farquhar ER, Marletta MA. A family of starch-active polysaccharide monooxygenases. Proc Natl Acad Sci. 2014;111(38):13822-7.
17. Leggio LL, Simmons TJ, Poulsen JCN, Frandsen KEH, Hemsworth GR, Stringer MA, et al. Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase. Nat Commun. 2015;. doi: 10.1038/ncomms6961.
18. Cannella D, Jørgensen H. Do new cellulolytic enzyme preparations affect the industrial strategies for high solids lignocellulosic ethanol production? Biotechnol Bioeng. 2014;111(1):59-68. doi: 10.1002/bit.25098.
19. Hu J, Chandra R, Arantes V, Gourlay K, van Dyk JS, Saddler JN. The addition of accessory enzymes enhances the hydrolytic performance of cellulase enzymes at high solid loadings. Bioresour Technol. 2015;186:149-53. doi: 10.1016/j.biortech.2015.03.055.
20. Kristensen JB, Felby C, Jørgensen H. Yield-determining factors in high-solids enzymatic hydrolysis of lignocellulose. Biotechnol Biofuels. 2009;2(1):11.
21. Vivekanand V, Olsen EF, Eijsink VGH, Horn SJ. Effect of different steam explosion conditions on methane potential and enzymatic saccharification of birch. Bioresour Technol. 2013;127:343-9. doi: 10.1016/j.biortech.2012.09.118.
22. Adav SS, Chao LT, Sze SK. Quantitative secretomic analysis of Trichoderma reesei strains reveals enzymatic composition for lignocellulosic biomass degradation. Mol Cell Proteomics. 2012;11(7):M111.012419. doi: 10.1074/mcp.M111.012419.
23. Felby C, Nielsen BR, Olesen PO, Skibsted LH. Identification and quantification of radical reaction intermediates by electron spin resonance spectrometry of laccase-catalyzed oxidation of wood fibers from beech (Fagus sylvatica). Appl Microbiol Biotechnol. 1997;48(4):459-64.
24. Kumar L, Arantes V, Chandra R, Saddler J. The lignin present in steam pretreated softwood binds enzymes and limits cellulose accessibility. Bioresour Technol. 2012;103(1):201-8.
25. Rodriguez-Zuniga UF, Cannella D, Giordano RC, Giordano RLC, Jorgensen H, Felby C. Lignocellulose pretreatment technologies affect the level of enzymatic cellulose oxidation by LPMO. Green Chem. 2015;17:2896-903. doi: 10.1039/C4GC02179G.
26. Jing X, Zhang X, Bao J. Inhibition performance of lignocellulose degradation products on industrial cellulase enzymes during cellulose hydrolysis. Appl Biochem Biotechnol. 2009;159(3):696-707. doi: 10.1007/s12010-009-8525-z.
27. Reese ET, Siu RGH, Levinson HS. The biological degradation of soluble cellulose derivatives and its relationship to the mechanism of cellulose hydrolysis. J Bacteriol. 1950;59(4):485-97.
28. Eriksson K-E, Pettersson B, Westermark U. Oxidation: An important enzyme reaction in fungal degradation of cellulose. FEBS Lett. 1974;49(2):282-5.
29. Eibinger M, Ganner T, Bubner P, Rošker S, Kracher D, Haltrich D, et al. Cellulose surface degradation by a lytic polysaccharide monooxygenase and its effect on cellulase hydrolytic efficiency. J Biol Chem. 2014;289(52):35929-38.
30. Wood TM. Preparation of crystalline, amorphous, and dyed cellulase substrates. In: Willis A, Wood STK, editors. Methods in enzymology. Academic Press; 1988. p. 19-25.
31. Kittl R, Kracher D, Burgstaller D, Haltrich D, Ludwig R. Production of four Neurospora crassa lytic polysaccharide monooxygenases in Pichia pastoris monitored by a fluorimetric assay. Biotechnol Biofuels. 2012;5:79. doi: 10.1186/1754-6834-5-79.
32. Jorgensen H, Vibe-Pedersen J, Larsen J, Felby C. Liquefaction of lignocellulose at high-solids concentrations. Biotechnol Bioeng. 2007;96(5):862-70.
33. Sipos B, Benko Z, Dienes D, Réczey K, Viikari L, Siika-aho M. Characterisation of specific activities and hydrolytic properties of cell-wall-degrading enzymes produced by Trichoderma reesei Rut C30 on different carbon sources. Appl Biochem Biotechnol. 2010;161(1-8):347-64.
34. Westereng B, Agger JW, Horn SJ, Vaaje-Kolstad G, Aachmann FL, Stenstrom YH, et al. Efficient separation of oxidized cello-oligosaccharides generated by cellulose degrading lytic polysaccharide monooxygenases. J Chromatogr A. 2013;1271:144-52. doi: 10.1016/j.chroma.2012.11.048.