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Volumn 22, Issue 11, 2015, Pages 883-888

Structural basis of template-boundary definition in Tetrahymena telomerase

Author keywords

[No Author keywords available]

Indexed keywords

RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; TELOMERASE RNA;

EID: 84947910284     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.3101     Document Type: Article
Times cited : (43)

References (32)
  • 1
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • Palm, W. & de Lange, T. How shelterin protects mammalian telomeres. Annu. Rev. Genet. 42, 301-334 (2008).
    • (2008) Annu. Rev. Genet. , vol.42 , pp. 301-334
    • Palm, W.1    De Lange, T.2
  • 2
    • 0026460896 scopus 로고
    • Telomere length predicts replicative capacity of human fibroblasts
    • Allsopp, R. C. et al. Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl. Acad. Sci. USA 89, 10114-10118 (1992).
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10114-10118
    • Allsopp, R.C.1
  • 3
    • 0023663881 scopus 로고
    • The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
    • Greider, C. W. & Blackburn, E. H. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell 51, 887-898 (1987).
    • (1987) Cell , vol.51 , pp. 887-898
    • Greider, C.W.1    Blackburn, E.H.2
  • 4
    • 36749012920 scopus 로고    scopus 로고
    • Dyskeratosis congenita: The diverse clinical presentation of mutations in the telomerase complex
    • Vulliamy, T. J. & Dokal, I. Dyskeratosis congenita: The diverse clinical presentation of mutations in the telomerase complex. Biochimie 90, 122-130 (2008).
    • (2008) Biochimie , vol.90 , pp. 122-130
    • Vulliamy, T.J.1    Dokal, I.2
  • 5
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim, N. W. et al. Specific association of human telomerase activity with immortal cells and cancer. Science 266, 2011-2015 (1994).
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1
  • 6
    • 0033134835 scopus 로고    scopus 로고
    • Telomerase RNA function in recombinant Tetrahymena telomerase
    • Licht, J. D. & Collins, K. Telomerase RNA function in recombinant Tetrahymena telomerase. Genes Dev. 13, 1116-1125 (1999).
    • (1999) Genes Dev. , vol.13 , pp. 1116-1125
    • Licht, J.D.1    Collins, K.2
  • 7
    • 0024978857 scopus 로고
    • A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
    • Greider, C. W. & Blackburn, E. H. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337, 331-337 (1989).
    • (1989) Nature , vol.337 , pp. 331-337
    • Greider, C.W.1    Blackburn, E.H.2
  • 8
    • 22544441637 scopus 로고    scopus 로고
    • A physical and functional constituent of telomerase anchor site
    • Lue, N. F. A physical and functional constituent of telomerase anchor site. J. Biol. Chem. 280, 26586-26591 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 26586-26591
    • Lue, N.F.1
  • 9
    • 34547433779 scopus 로고    scopus 로고
    • High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase
    • Romi, E. et al. High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase. Proc. Natl. Acad. Sci. USA 104, 8791-8796 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 8791-8796
    • Romi, E.1
  • 10
    • 49449094794 scopus 로고    scopus 로고
    • Mutation in TERT separates processivity from anchor-site function
    • Zaug, A. J., Podell, E. R. & Cech, T. R. Mutation in TERT separates processivity from anchor-site function. Nat. Struct. Mol. Biol. 15, 870-872 (2008).
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 870-872
    • Zaug, A.J.1    Podell, E.R.2    Cech, T.R.3
  • 11
    • 77950471767 scopus 로고    scopus 로고
    • Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA
    • Mitchell, M., Gillis, A., Futahashi, M., Fujiwara, H. & Skordalakes, E. Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA. Nat. Struct. Mol. Biol. 17, 513-518 (2010).
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 513-518
    • Mitchell, M.1    Gillis, A.2    Futahashi, M.3    Fujiwara, H.4    Skordalakes, E.5
  • 12
    • 84902440664 scopus 로고    scopus 로고
    • Coordinated DNA dynamics during the human telomerase catalytic cycle
    • Parks, J. W. & Stone, M. D. Coordinated DNA dynamics during the human telomerase catalytic cycle. Nat. Commun. 5, 4146 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 4146
    • Parks, J.W.1    Stone, M.D.2
  • 13
    • 82955237444 scopus 로고    scopus 로고
    • The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis
    • Berman, A. J., Akiyama, B. M., Stone, M. D. & Cech, T. R. The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis. Nat. Struct. Mol. Biol. 18, 1371-1375 (2011).
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 1371-1375
    • Berman, A.J.1    Akiyama, B.M.2    Stone, M.D.3    Cech, T.R.4
  • 14
    • 20444481334 scopus 로고    scopus 로고
    • Two purified domains of telomerase reverse transcriptase reconstitute sequence-specific interactions with RNA
    • O'Connor, C. M., Lai, C. K. & Collins, K. Two purified domains of telomerase reverse transcriptase reconstitute sequence-specific interactions with RNA. J. Biol. Chem. 280, 17533-17539 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 17533-17539
    • O'Connor, C.M.1    Lai, C.K.2    Collins, K.3
  • 15
    • 33644800744 scopus 로고    scopus 로고
    • Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase
    • Jacobs, S. A., Podell, E. R. & Cech, T. R. Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase. Nat. Struct. Mol. Biol. 13, 218-225 (2006).
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 218-225
    • Jacobs, S.A.1    Podell, E.R.2    Cech, T.R.3
  • 16
    • 84936806667 scopus 로고    scopus 로고
    • The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids
    • Akiyama, B. M., Parks, J. W. & Stone, M. D. The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids. Nucleic Acids Res. 43, 5537-5549 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , pp. 5537-5549
    • Akiyama, B.M.1    Parks, J.W.2    Stone, M.D.3
  • 17
    • 0033636319 scopus 로고    scopus 로고
    • Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase
    • Bryan, T. M., Goodrich, K. J. & Cech, T. R. Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase. Mol. Cell 6, 493-499 (2000).
    • (2000) Mol. Cell , vol.6 , pp. 493-499
    • Bryan, T.M.1    Goodrich, K.J.2    Cech, T.R.3
  • 18
    • 0035144580 scopus 로고    scopus 로고
    • RNA binding domain of telomerase reverse transcriptase
    • Lai, C. K., Mitchell, J. R. & Collins, K. RNA binding domain of telomerase reverse transcriptase. Mol. Cell. Biol. 21, 990-1000 (2001).
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 990-1000
    • Lai, C.K.1    Mitchell, J.R.2    Collins, K.3
  • 19
    • 33744799697 scopus 로고    scopus 로고
    • Structure and function of telomerase RNA
    • Theimer, C. A. & Feigon, J. Structure and function of telomerase RNA. Curr. Opin. Struct. Biol. 16, 307-318 (2006).
    • (2006) Curr. Opin. Struct. Biol. , vol.16 , pp. 307-318
    • Theimer, C.A.1    Feigon, J.2
  • 20
    • 0037083759 scopus 로고    scopus 로고
    • Template boundary definition in Tetrahymena telomerase
    • Lai, C. K., Miller, M. C. & Collins, K. Template boundary definition in Tetrahymena telomerase. Genes Dev. 16, 415-420 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 415-420
    • Lai, C.K.1    Miller, M.C.2    Collins, K.3
  • 21
    • 84881218314 scopus 로고    scopus 로고
    • A conserved motif in Tetrahymena thermophila telomerase reverse transcriptase is proximal to the RNA template and is essential for boundary definition
    • Akiyama, B. M., Gomez, A. & Stone, M. D. A conserved motif in Tetrahymena thermophila telomerase reverse transcriptase is proximal to the RNA template and is essential for boundary definition. J. Biol. Chem. 288, 22141-22149 (2013).
    • (2013) J. Biol. Chem. , vol.288 , pp. 22141-22149
    • Akiyama, B.M.1    Gomez, A.2    Stone, M.D.3
  • 22
    • 0034664006 scopus 로고    scopus 로고
    • Template definition by Tetrahymena telomerase reverse transcriptase
    • Miller, M. C., Liu, J. K. & Collins, K. Template definition by Tetrahymena telomerase reverse transcriptase. EMBO J. 19, 4412-4422 (2000).
    • (2000) EMBO J. , vol.19 , pp. 4412-4422
    • Miller, M.C.1    Liu, J.K.2    Collins, K.3
  • 23
    • 35748951600 scopus 로고    scopus 로고
    • Structure of the RNA-binding domain of telomerase: Implications for RNA recognition and binding
    • Rouda, S. & Skordalakes, E. Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding. Structure 15, 1403-1412 (2007).
    • (2007) Structure , vol.15 , pp. 1403-1412
    • Rouda, S.1    Skordalakes, E.2
  • 24
    • 53349161932 scopus 로고    scopus 로고
    • Structure of the Tribolium castaneum telomerase catalytic subunit TERT
    • Gillis, A. J., Schuller, A. P. & Skordalakes, E. Structure of the Tribolium castaneum telomerase catalytic subunit TERT. Nature 455, 633-637 (2008).
    • (2008) Nature , vol.455 , pp. 633-637
    • Gillis, A.J.1    Schuller, A.P.2    Skordalakes, E.3
  • 25
    • 84885418090 scopus 로고    scopus 로고
    • A motif in the vertebrate telomerase N-terminal linker of TERT contributes to RNA binding and telomerase activity and processivity
    • Harkisheimer, M., Mason, M., Shuvaeva, E. & Skordalakes, E. A motif in the vertebrate telomerase N-terminal linker of TERT contributes to RNA binding and telomerase activity and processivity. Structure 21, 1870-1878 (2013).
    • (2013) Structure , vol.21 , pp. 1870-1878
    • Harkisheimer, M.1    Mason, M.2    Shuvaeva, E.3    Skordalakes, E.4
  • 26
    • 84901985293 scopus 로고    scopus 로고
    • Structural basis for protein-RNA recognition in telomerase
    • Huang, J. et al. Structural basis for protein-RNA recognition in telomerase. Nat. Struct. Mol. Biol. 21, 507-512 (2014).
    • (2014) Nat. Struct. Mol. Biol. , vol.21 , pp. 507-512
    • Huang, J.1
  • 27
    • 0028917206 scopus 로고
    • Ciliate telomerase RNA structural features
    • McCormick-Graham, M. & Romero, D. P. Ciliate telomerase RNA structural features. Nucleic Acids Res. 23, 1091-1097 (1995).
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1091-1097
    • McCormick-Graham, M.1    Romero, D.P.2
  • 28
    • 18944391463 scopus 로고    scopus 로고
    • Biological and biochemical functions of RNA in the Tetrahymena telomerase holoenzyme
    • Cunningham, D. D. & Collins, K. Biological and biochemical functions of RNA in the Tetrahymena telomerase holoenzyme. Mol. Cell. Biol. 25, 4442-4454 (2005).
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 4442-4454
    • Cunningham, D.D.1    Collins, K.2
  • 29
    • 33644864313 scopus 로고    scopus 로고
    • Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element
    • Richards, R. J., Theimer, C. A., Finger, L. D. & Feigon, J. Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element. Nucleic Acids Res. 34, 816-825 (2006).
    • (2006) Nucleic Acids Res. , vol.34 , pp. 816-825
    • Richards, R.J.1    Theimer, C.A.2    Finger, L.D.3    Feigon, J.4
  • 30
    • 84876287616 scopus 로고    scopus 로고
    • The architecture of Tetrahymena telomerase holoenzyme
    • Jiang, J. et al. The architecture of Tetrahymena telomerase holoenzyme. Nature 496, 187-192 (2013).
    • (2013) Nature , vol.496 , pp. 187-192
    • Jiang, J.1
  • 31
    • 0344011566 scopus 로고    scopus 로고
    • Template boundary definition in mammalian telomerase
    • Chen, J. L. & Greider, C. W. Template boundary definition in mammalian telomerase. Genes Dev. 17, 2747-2752 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 2747-2752
    • Chen, J.L.1    Greider, C.W.2
  • 32
    • 84905662409 scopus 로고    scopus 로고
    • A self-regulating template in human telomerase
    • Brown, A. F. et al. A self-regulating template in human telomerase. Proc. Natl. Acad. Sci. USA 111, 11311-11316 (2014).
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 11311-11316
    • Brown, A.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.