A conserved motif in tetrahymena thermophila telomerase reverse transcriptase is proximal to the RNA template and is essential for boundary definition

Journal of Biological Chemistry

Volumn 288, Issue 30, 2013, Pages 22141-22149

  Akiyama, Benjamin M ^a   Gomez, Anastassia ^a   Stone, Michael D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOUNDARY DEFINITION; CONSERVED PROTEINS; HYDROXYL RADICALS; MECHANISTIC MODELS; PROTEIN MOTIFS; RNA-PROTEIN INTERACTIONS; TELOMERASE REVERSE TRANSCRIPTASE; TETRAHYMENA THERMOPHILA;

PROTEINS;

RNA;

HYDROXYL RADICAL; NUCLEOTIDE; RNA; TELOMERASE REVERSE TRANSCRIPTASE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA STRAND; DNA TEMPLATE; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME STRUCTURE; MOLECULAR MECHANICS; MOLECULAR PROBE; NONHUMAN; NUCLEOTIDE BINDING SITE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN RNA BINDING; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION; RNA STRUCTURE; SITE DIRECTED MUTAGENESIS; TEMPLATE BOUNDARY ELEMENT; TETRAHYMENA THERMOPHILA;

RIBONUCLEAR PROTEIN (RNP); RNA; RNA-BINDING PROTEIN; TELOMERASE; TELOMERES;

AMINO ACID MOTIFS; BASE SEQUENCE; BINDING SITES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; NUCLEOTIDE MOTIFS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; RNA; RNA, PROTOZOAN; TELOMERASE; TEMPLATES, GENETIC; TETRAHYMENA THERMOPHILA;

EID: 84881218314     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.452425     Document Type: Article

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