Heparin interaction with a receptor on hyperglycemic dividing cells prevents intracellular hyaluronan synthesis and autophagy responses in models of type 1 diabetes

Matrix Biology

Volumn 48, Issue , 2015, Pages 36-41

  Wang, Aimin ^a   Sankaranarayanan, Nehru Viji ^b   Yanagishita, Masaki ^c   Templeton, Douglas M ^d   Desai, Umesh R ^b   Sugahara, Kazuyuki ^e   Wang, Christina P ^a   Hascall, Vincent C ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d UNIVERSITY OF TORONTO   (Canada)

^e MEIJO UNIVERSITY   (Japan)

Author keywords

Heparan sulfate; Heparanase; Heparin; Heparitinase; Hyaluronan

Indexed keywords

CELL SURFACE RECEPTOR; HEPARAN SULFATE; HEPARANASE; HEPARIN; HEPARIN FRAGMENT; HYALURONIC ACID; HYALURONIDASE; PROTEOHEPARAN SULFATE; SYNDECAN; BETA GLUCURONIDASE; PROTEOGLYCAN; SERGLYCIN; VESICULAR TRANSPORT PROTEIN;

AUTOPHAGY; CELL DIVISION; ENDOCYTOSIS; GLYCOSAMINOGLYCAN METABOLISM; GRANULOSA CELL; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MAST CELL; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MOTIF; REVIEW; SECRETORY GRANULE; ANIMAL; BIOSYNTHESIS; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; ENDOSOME; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENETICS; METABOLISM; PATHOLOGY; RAT; SECRETORY VESICLE;

ANIMALS; AUTOPHAGY; CELL DIVISION; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; ENDOSOMES; EXTRACELLULAR MATRIX; GENE EXPRESSION; GLUCURONIDASE; HEPARIN; HEPARITIN SULFATE; HUMANS; HYALURONIC ACID; MAST CELLS; MESANGIAL CELLS; PROTEOGLYCANS; RATS; RECEPTORS, CELL SURFACE; SECRETORY VESICLES; VESICULAR TRANSPORT PROTEINS;

EID: 84947868519     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2015.04.003     Document Type: Review

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