High-throughput sequencing insights into T-cell receptor repertoire diversity in aging

Genome Medicine

Volumn 7, Issue 1, 2015, Pages

  Goronzy, Jörg J ^a,b   Qi, Qian ^a,b   Olshen, Richard A ^a   Weyand, Cornelia M ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; BIOLOGICAL MARKER; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR;

AGING; AMINO ACID SEQUENCE; ANTIBODY DETECTION; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CANCER CHEMOTHERAPY; CANCER INCIDENCE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL LOSS; CELL REGENERATION; CLONAL VARIATION; CROSS REACTION; CYTOMEGALOVIRUS INFECTION; DIAGNOSTIC ACCURACY; DRUG RESPONSE; EFFECTOR CELL; GENE; GENE DELETION; GENE INSERTION; GENETIC VARIABILITY; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; IMMUNOCOMPETENCE; IMMUNOREACTIVITY; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; INFLAMMATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOPOIESIS; MATHEMATICAL MODEL; MEMORY T LYMPHOCYTE; MOLECULAR CLONING; MORTALITY; NEOPLASM; NONHUMAN; NOTE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STEM CELL TRANSPLANTATION; T CELL DEPLETION; T LYMPHOCYTE; TCR GENE; THYMUS; VACCINATION; ANIMAL; CELL CLONE; GENETIC VARIATION; GENETICS; IMMUNOLOGY; MOUSE; PROCEDURES;

AGING; ANIMALS; CLONE CELLS; GENETIC VARIATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MICE; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 84947738985     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/s13073-015-0242-3     Document Type: Note

References (10)

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