Anti-aquaporin-4 antibody induces astrocytic cytotoxicity in the absence of CNS antigen-specific T cells

Biochemical and Biophysical Research Communications

Volumn 394, Issue 1, 2010, Pages 205-210

  Kinoshita, Makoto ^a   Nakatsuji, Yuji ^a   Kimura, Takashi ^c   Moriya, Masayuki ^a   Takata, Kazushiro ^a   Okuno, Tatsusada ^b   Kumanogoh, Atsushi ^b   Kajiyama, Koji ^c   Yoshikawa, Hiroo ^c   Sakoda, Saburo ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Animal model; Aquaporin 4; Astrocyte; Multiple sclerosis; Neuromyelitis optica; T cell

Indexed keywords

AQUAPORIN 4 AUTOANTIBODY; AUTOANTIBODY; COMPLEMENT; FREUND ADJUVANT; IMMUNOGLOBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY TITER; ANTIGEN SPECIFICITY; ARTICLE; ASTROCYTE; CELL INFILTRATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GRANULOCYTE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MYELOOPTIC NEUROPATHY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; SPINAL CORD; T LYMPHOCYTE;

ANIMALS; AQUAPORIN 4; ASTROCYTES; AUTOANTIBODIES; CENTRAL NERVOUS SYSTEM; CYTOTOXICITY, IMMUNOLOGIC; FREUND'S ADJUVANT; HUMANS; NEUROMYELITIS OPTICA; RATS; RATS, INBRED LEW; T-LYMPHOCYTES;

ANIMALIA;

EID: 77949875218     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.02.157     Document Type: Article

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