Risk of Thyroid Follicular Adenoma Among Children and Adolescents in Belarus Exposed to Iodine-131 After the Chornobyl Accident

American Journal of Epidemiology

Volumn 182, Issue 9, 2015, Pages 781-790

  Zablotska, Lydia B ^a   Nadyrov, Eldar A ^b   Polyanskaya, Olga N ^b   McConnell, Robert J ^c   O'Kane, Patrick ^d   Lubin, Jay ^e   Hatch, Maureen ^e   Little, Mark P ^e   Brenner, Alina V ^e   Veyalkin, Ilya V ^b   Yauseyenka, Vasilina V ^b   Bouville, Andre ^e   Drozdovitch, Vladimir V ^e   Minenko, Viktor F ^f   Demidchik, Yuri E ^g   Mabuchi, Kiyohiko ^e   Rozhko, Alexander V ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Republican Research Center for Radiation Medicine and Human Ecology   (Belarus)

^c Howard Hughes Medical Institute   (United States)

^d THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f INSTITUTE FOR NUCLEAR PROBLEMS   (Belarus)

^g N N Alexandrov National Cancer Center   (Belarus)

Author keywords

adenoma; Chornobyl nuclear accident; dose response relationship; interaction; iodine deficiency; iodine radioisotopes; radiation; thyroid neoplasms

Indexed keywords

IODINE 131; RADIOACTIVE IODINE;

ADOLESCENCE; CANCER; DOSE-RESPONSE RELATIONSHIP; EPIDEMIOLOGY; HEALTH RISK; IODIDE; MEDICAL GEOGRAPHY; NUCLEAR POWER PLANT; POLLUTION EXPOSURE; RADIATION EXPOSURE; RADIOACTIVE POLLUTION; RADIONUCLIDE; RISK ASSESSMENT; TUMOR;

ADOLESCENT; ADULT; ARTICLE; BELARUS; CANCER RISK; CHERNOBYL ACCIDENT; CHILD; CLINICAL ARTICLE; DOSE RESPONSE; FALLOUT; FEMALE; HUMAN; HUMAN TISSUE; IODINE DEFICIENCY; MALE; RADIATION DOSE; RADIATION HAZARD; RADIOACTIVITY; SCHOOL CHILD; THYROID ADENOMA; THYROID FOLLICULAR ADENOMA; YOUNG ADULT; ADENOMA; ENVIRONMENTAL EXPOSURE; NEOPLASMS, RADIATION-INDUCED; PREVALENCE; RADIATION RESPONSE; RISK FACTOR; THYROID NEOPLASMS;

BELARUS; CHERNOBYL; KIEV [UKRAINE]; UKRAINE;

ADENOMA; ADOLESCENT; ADULT; CHERNOBYL NUCLEAR ACCIDENT; CHILD; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; IODINE RADIOISOTOPES; MALE; NEOPLASMS, RADIATION-INDUCED; PREVALENCE; RISK FACTORS; THYROID NEOPLASMS;

EID: 84947583155     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwv127     Document Type: Article

References (38)

1. Ron E, Lubin JH, Shore RE, et al. Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies. Radiat Res. 1995;141(3):259-277.
2. United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). 2006 Report to the General Assembly with Scientific Annexes. Vol. I. Annex A: Epidemiological studies of radiation and cancer. New York, NY: UNSCEAR; 2008.
3. National Council on Radiation Protection and Measurements. Risk to the Thyroid From Ionizing Radiation. Bethesda, MD: National Council on Radiation Protection and Measurements; 2008. (NCRP report no. 159).
4. Stezhko VA, Buglova EE, Danilova LI, et al. A cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident: objectives, design and methods. Radiat Res. 2004;161(4):481-492.
5. Tronko MD, Howe GR, Bogdanova TI, et al. A cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident: thyroid cancer in Ukraine detected during first screening. J Natl Cancer Inst. 2006;98(13):897-903.
6. Brenner AV, Tronko MD, Hatch M, et al. I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accident. Environ Health Perspect. 2011;119(7):933-939.
7. Little MP, Kukush AG, Masiuk SV, et al. Impact of uncertainties in exposure assessment on estimates of thyroid cancer risk among Ukrainian children and adolescents exposed from the Chernobyl accident. PLoS One. 2014;9(1):e85723.
8. Zablotska LB, Ron E, Rozhko AV, et al. Thyroid cancer risk in Belarus among children and adolescents exposed to radioiodine after the Chornobyl accident. Br J Cancer. 2011;104(1):181-187.
9. Adams MJ, Shore RE, Dozier A, et al. Thyroid cancer risk 40+ years after irradiation for an enlarged thymus: an update of the Hempelmann cohort. Radiat Res. 2010;174(6):753-762.
10. Veiga LH, Lubin JH, Anderson H, et al. A pooled analysis of thyroid cancer incidence following radiotherapy for childhood cancer. Radiat Res. 2012;178(4):365-376.
11. Ron E, Modan B, Preston D, et al. Thyroid neoplasia following low-dose radiation in childhood. Radiat Res. 1989;120(3):516-531.
12. Shore RE, Hildreth N, Dvoretsky P, et al. Benign thyroid adenomas among persons X-irradiated in infancy for enlarged thymus glands. Radiat Res. 1993;134(2):217-223.
13. Shore RE, Moseson M, Harley N, et al. Tumors and other diseases following childhood x-ray treatment for ringworm of the scalp (tinea capitis). Health Phys. 2003;85(4):404-408.
14. Haddy N, El-Fayech C, Guibout C, et al. Thyroid adenomas after solid cancer in childhood. Int J Radiat Oncol Biol Phys. 2012;84(2):e209-e215.
15. Schneider AB, Ron E, Lubin J, et al. Dose-response relationships for radiation-induced thyroid cancer and thyroid nodules: evidence for the prolonged effects of radiation on the thyroid. J Clin Endocrinol Metab. 1993;77(2):362-369.
16. Haddy N, Andriamboavonjy T, Paoletti C, et al. Thyroid adenomas and carcinomas following radiotherapy for a hemangioma during infancy. Radiother Oncol. 2009;93(2):377-382.
17. Imaizumi M, Usa T, Tominaga T, et al. Radiation dose-response relationships for thyroid nodules and autoimmune thyroid diseases in Hiroshima and Nagasaki atomic bomb survivors 55-58 years after radiation exposure. JAMA. 2006;295(9):1011-1022.
18. Imaizumi M, Ohishi W, Nakashima E, et al. Association of radiation dose with prevalence of thyroid nodules among atomic bomb survivors exposed in childhood (2007-2011). JAMA Intern Med. 2015;175(2):228-236.
19. Zablotska LB, Bogdanova TI, Ron E, et al. A cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident: dose-response analysis of thyroid follicular adenomas detected during first screening in Ukraine (1998-2000). Am J Epidemiol. 2008;167(3):305-312.
20. Drozdovitch V, Minenko V, Khrouch V, et al. Thyroid dose estimates for a cohort of Belarusian children exposed to radiation from the Chernobyl accident. Radiat Res. 2013;179(5):597-609.
21. Zablotska LB, Nadyrov EA, Rozhko AV, et al. Analysis of thyroid malignant pathologic findings identified during 3 rounds of screening (1997-2008) of a cohort of children and adolescents from Belarus exposed to radioiodines after the Chernobyl accident. Cancer. 2015;121(3):457-466.
22. World Health Organization. Pathology and Genetics of Tumours of Endocrine Organs. Lyon, France: International Agency for Research on Cancer; 2004.
23. Singer PA, Cooper DS, Daniels GH, et al. Treatment guidelines for patients with thyroid nodules and well-differentiated thyroid cancer. American Thyroid Association. Arch Intern Med. 1996;156(19):2165-2172.
24. Brunn J, Block U, Ruf G, et al. Volumetric analysis of thyroid lobes by real-time ultrasound [in German]. Dtsch Med Wochenschr. 1981;106(41):1338-1340.
25. Skryabin AM, Drozdovitch V, Belsky Y, et al. Thyroid mass in children and adolescents living in the most exposed areas to Chernobyl fallout in Belarus. Radiat Prot Dosimetry. 2010;142(2-4):292-299.
26. Drozdovitch V, Zhukova O, Germenchuk M, et al. Database of meteorological and radiation measurements made in Belarus during the first three months following the Chernobyl accident. J Environ Radioact. 2013;116:84-92.
27. Breslow NE, Day NE. Statistical Methods in Cancer Research. Vol 2. The Design and Analysis of Cohort Studies. Lyon, France: International Agency for Research on Cancer; 1987.
28. Preston DL, Lubin JH, Pierce DA, et al. EPICURE User's Guide. Seattle, WA: Hirosoft International Corporation; 1993.
29. McCullagh P, Nelder JA. Generalized Linear Models. 2nd ed. Boca Raton, FL: Chapman & Hall/CRC; 1989.
30. LiVolsi VA, Abrosimov AA, Bogdanova T, et al. The Chernobyl thyroid cancer experience: pathology. Clin Oncol (R Coll Radiol). 2011;23(4):261-267.
31. Davis S, Kopecky KJ, Hamilton TE, et al. Thyroid neoplasia, autoimmune thyroiditis, and hypothyroidism in persons exposed to iodine 131 from the Hanford nuclear site. JAMA. 2004;292(21):2600-2613.
32. Lyon JL, Alder SC, Stone MB, et al. Thyroid disease associated with exposure to the Nevada nuclear weapons test site radiation: a reevaluation based on corrected dosimetry and examination data. Epidemiology. 2006;17(6):604-614.
33. Cooper DS, Doherty GM, Haugen BR, et al. Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2006;16(2):109-142.
34. Cardis E, Kesminiene A, Ivanov V, et al. Risk of thyroid cancer after exposure to 131I in childhood. J Natl Cancer Inst. 2005;97(10):724-732.
35. Kholodova EA, Fedorova LP. Epidemiology of endemic goiter in Belarus. IDD Newsletter. 1992;8(1).
36. Gerasimov G. Update on IDD in the former USSR. IDD Newsletter. 1993;9(4):43-48.
37. Utiger RD. The multiplicity of thyroid nodules and carcinomas. N Engl J Med. 2005;352(23):2376-2378.
38. Ron E, Brenner A. Non-malignant thyroid diseases after a wide range of radiation exposures. Radiat Res. 2010;174(6):877-888.