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Volumn 13, Issue 11, 2015, Pages 1213-1223

Evaluating coagulation tests in patients with atrial fibrillation using direct oral anticoagulants

Author keywords

anticoagulants; atrial fibrillation; coagulation; direct oral anticoagulant; laboratory; monitoring; NOACs; stroke

Indexed keywords

APIXABAN; BLOOD CLOTTING FACTOR 10A; DABIGATRAN; EDOXABAN; RIVAROXABAN; THROMBIN; THROMBOPLASTIN; WARFARIN; ANTICOAGULANT AGENT;

EID: 84947489452     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/14779072.2015.1096779     Document Type: Review
Times cited : (1)

References (68)
  • 1
    • 70349306707 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in patients with atrial fibrillation
    • Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361 (12): 1139-51
    • (2009) N Engl J Med , vol.361 , Issue.12 , pp. 1139-1151
    • Connolly, S.J.1    Ezekowitz, M.D.2    Yusuf, S.3
  • 2
    • 80052592404 scopus 로고    scopus 로고
    • Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
    • Patel MR, Mahaffey KW, Garg J, et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 2011; 365 (10): 883-91
    • (2011) N Engl J Med , vol.365 , Issue.10 , pp. 883-891
    • Patel, M.R.1    Mahaffey, K.W.2    Garg, J.3
  • 3
    • 80052825103 scopus 로고    scopus 로고
    • Apixaban versus warfarin in patients with atrial fibrillation
    • Granger CB, Alexander JH, McMurray JJV, et al. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med 2011; 365 (11): 981-92
    • (2011) N Engl J Med , vol.365 , Issue.11 , pp. 981-992
    • Granger, C.B.1    Alexander, J.H.2    McMurray, J.J.V.3
  • 4
    • 84888362796 scopus 로고    scopus 로고
    • Edoxaban versus warfarin in patients with atrial fibrillation
    • Giugliano RP, Ruff CT, Braunwald E, et al. Edoxaban versus warfarin in patients with atrial fibrillation. N Engl J Med 2013; 369 (22): 2093-104
    • (2013) N Engl J Med , vol.369 , Issue.22 , pp. 2093-2104
    • Giugliano, R.P.1    Ruff, C.T.2    Braunwald, E.3
  • 5
    • 84931559772 scopus 로고    scopus 로고
    • Overview of the new oral anticoagulants: Opportunities and challenges
    • Yeh CH, Hogg K, Weitz JI. Overview of the new oral anticoagulants: opportunities and challenges. Arterioscler Thromb Vasc Biol 2015; 35 (5): 1056-65
    • (2015) Arterioscler Thromb Vasc Biol , vol.35 , Issue.5 , pp. 1056-1065
    • Yeh, C.H.1    Hogg, K.2    Weitz, J.I.3
  • 6
    • 84876192857 scopus 로고    scopus 로고
    • Measuring Oral Direct Inhibitors (ODIs) of thrombin and factor Xa: A recommendation from the Subcommittee on Control of Anticoagulation of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis
    • Epub ahead of print
    • Baglin T, Hillarp A, Tripodi A, et al. Measuring Oral Direct Inhibitors (ODIs) of thrombin and factor Xa: A recommendation from the Subcommittee on Control of Anticoagulation of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis. J Thromb Haemost 2013. [Epub ahead of print]
    • (2013) J Thromb Haemost
    • Baglin, T.1    Hillarp, A.2    Tripodi, A.3
  • 7
    • 84873544394 scopus 로고    scopus 로고
    • Laboratory assessment of the anticoagulant effects of the next generation of oral anticoagulants
    • Garcia D, Barrett YC, Ramacciotti E, Weitz JI. Laboratory assessment of the anticoagulant effects of the next generation of oral anticoagulants. J Thromb Haemost 2013; 11 (2): 245-52
    • (2013) J Thromb Haemost , vol.11 , Issue.2 , pp. 245-252
    • Garcia, D.1    Barrett, Y.C.2    Ramacciotti, E.3    Weitz, J.I.4
  • 8
    • 84856593171 scopus 로고    scopus 로고
    • Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran
    • Stangier J, Feuring M. Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran. Blood Coagul Fibrinolysis 2012; 23 (2): 138-43
    • (2012) Blood Coagul Fibrinolysis , vol.23 , Issue.2 , pp. 138-143
    • Stangier, J.1    Feuring, M.2
  • 9
    • 84856632988 scopus 로고    scopus 로고
    • Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls
    • Samama MM, Contant G, Spiro TE, et al. Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls. Thromb Haemost 2012; 107 (2): 379-87
    • (2012) Thromb Haemost , vol.107 , Issue.2 , pp. 379-387
    • Samama, M.M.1    Contant, G.2    Spiro, T.E.3
  • 10
    • 78649736882 scopus 로고    scopus 로고
    • Clinical laboratory measurement of direct factor Xa inhibitors: Anti-Xa assay is preferable to prothrombin time assay
    • Barrett YC, Wang Z, Frost C, Shenker A. Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay. Thromb Haemost 2010; 104 (6): 1263-71
    • (2010) Thromb Haemost , vol.104 , Issue.6 , pp. 1263-1271
    • Barrett, Y.C.1    Wang, Z.2    Frost, C.3    Shenker, A.4
  • 11
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate-A novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
    • van Ryn J, Stangier J, Haertter S, et al. Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost 2010; 103 (6): 1116-27
    • (2010) Thromb Haemost , vol.103 , Issue.6 , pp. 1116-1127
    • Van Ryn, J.1    Stangier, J.2    Haertter, S.3
  • 12
    • 84922394366 scopus 로고    scopus 로고
    • Laboratory measurement of the anticoagulant activity of the non-Vitamin K oral anticoagulants
    • Cuker A, Siegal DM, Crowther MA, Garcia DA. Laboratory measurement of the anticoagulant activity of the non-vitamin K oral anticoagulants. J Am Coll Cardiol 2014; 64 (11): 1128-39
    • (2014) J Am Coll Cardiol , vol.64 , Issue.11 , pp. 1128-1139
    • Cuker, A.1    Siegal, D.M.2    Crowther, M.A.3    Garcia, D.A.4
  • 13
    • 84899727733 scopus 로고    scopus 로고
    • New oral anticoagulants for stroke prevention in atrial fibrillation: Impact of study design, double counting and unexpected findings on interpretation of study results and conclusions
    • Chan NC, Paikin JS, Hirsh J, et al. New oral anticoagulants for stroke prevention in atrial fibrillation: impact of study design, double counting and unexpected findings on interpretation of study results and conclusions. Thromb Haemost 2014; 111 (5): 798-807
    • (2014) Thromb Haemost , vol.111 , Issue.5 , pp. 798-807
    • Chan, N.C.1    Paikin, J.S.2    Hirsh, J.3
  • 14
    • 84863224773 scopus 로고    scopus 로고
    • Dabigatran, rivaroxaban, or apixaban versus enoxaparin for thromboprophylaxis after total hip or knee replacement: Systematic review, meta-analysis, and indirect treatment comparisons
    • Gómez-Outes A, Terleira-Fernández AI, Suárez-Gea ML, Vargas-Castrillón E. Dabigatran, rivaroxaban, or apixaban versus enoxaparin for thromboprophylaxis after total hip or knee replacement: systematic review, meta-analysis, and indirect treatment comparisons. BMJ 2012 344: e3675-2012
    • (2012) BMJ 2012 , vol.344 , pp. e3675-e3712
    • Gómez-Outes, A.1    Terleira-Fernández, A.I.2    Suárez-Gea, M.L.3    Vargas-Castrillón, E.4
  • 15
    • 84905977363 scopus 로고    scopus 로고
    • Evolving use of new oral anticoagulants for treatment of venous thromboembolism
    • Yeh CH, Gross PL, Weitz JI. Evolving use of new oral anticoagulants for treatment of venous thromboembolism. Blood 2014; 124 (7): 1020-8
    • (2014) Blood , vol.124 , Issue.7 , pp. 1020-1028
    • Yeh, C.H.1    Gross, P.L.2    Weitz, J.I.3
  • 16
    • 84947501713 scopus 로고    scopus 로고
    • Measurement of dabigatran, rivaroxaban and apixaban in samples of plasma, serum and urine, under real life conditions. An international study
    • Epub ahead of print
    • Harenberg J, Du S, Wehling M, et al. Measurement of dabigatran, rivaroxaban and apixaban in samples of plasma, serum and urine, under real life conditions. An international study. Clin Chem Lab Med 2015; Epub ahead of print
    • (2015) Clin Chem Lab Med
    • Harenberg, J.1    Du, S.2    Wehling, M.3
  • 17
    • 84880571372 scopus 로고    scopus 로고
    • Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: Proposals of the working group on perioperative haemostasis (GIHP) - March 2013
    • Pernod G, Albaladejo P, Godier A, et al. Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP)-March 2013. Arch Cardiovasc Dis 2013; 106 (6-7): 382-93
    • (2013) Arch Cardiovasc Dis , vol.106 , Issue.67 , pp. 382-393
    • Pernod, G.1    Albaladejo, P.2    Godier, A.3
  • 18
    • 84902084942 scopus 로고    scopus 로고
    • Management of acute stroke in patients taking novel oral anticoagulants
    • Hankey GJ, Norrving B, Hacke W, Steiner T. Management of acute stroke in patients taking novel oral anticoagulants. Int J Stroke 2014; 9 (5): 627-32
    • (2014) Int J Stroke , vol.9 , Issue.5 , pp. 627-632
    • Hankey, G.J.1    Norrving, B.2    Hacke, W.3    Steiner, T.4
  • 19
    • 84880280696 scopus 로고    scopus 로고
    • EHRA practical guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation: Executive summary
    • Heidbuchel H, Verhamme P, Alings M, et al. EHRA practical guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation: executive summary. Eur Heart J 2013; 34 (27): 2094-106
    • (2013) Eur Heart J , vol.34 , Issue.27 , pp. 2094-2106
    • Heidbuchel, H.1    Verhamme, P.2    Alings, M.3
  • 20
    • 84923811544 scopus 로고    scopus 로고
    • Real-world variability in dabigatran levels in patients with atrial fibrillation
    • Chan NC, Coppens M, Hirsh J, et al. Real-world variability in dabigatran levels in patients with atrial fibrillation. J Thromb Haemost 2015; 13 (3): 353-9
    • (2015) J Thromb Haemost , vol.13 , Issue.3 , pp. 353-359
    • Chan, N.C.1    Coppens, M.2    Hirsh, J.3
  • 21
    • 84937521948 scopus 로고    scopus 로고
    • US Food and Drug Administration [Last accessed 12 September 2015]
    • US Food and Drug Administration. Pradaxa: Highlights of prescribing information. Available from: www.accessdata.fda.gov/drugsatfda-docs/label/2011/022512s007lbl.pdf. [Last accessed 12 September 2015]
    • Pradaxa: Highlights of Prescribing Information
  • 22
    • 84937521948 scopus 로고    scopus 로고
    • US Food and Drug Administration [Last accessed 12 September 2015]
    • US Food and Drug Administration. Xarelto: Highlights of prescribing information. Available from: www.accessdata.fda.gov/drugsatfda-docs/label/2011/202439s001lbl.pdf. [Last accessed 12 September 2015]
    • Xarelto: Highlights of Prescribing Information
  • 23
    • 84937521948 scopus 로고    scopus 로고
    • US Food and Drug Administration [Last accessed 12 September 2015]
    • US Food and Drug Administration. Eliquis: Highlights of prescribing information. Available from: www.accessdata.fda.gov/drugsatfda-docs/label/2012/202155s000lbl.pdf. [Last accessed 12 September 2015]
    • Eliquis: Highlights of Prescribing Information
  • 24
    • 84937521948 scopus 로고    scopus 로고
    • US Food and Drug Administration [Last accessed 12 September 2015]
    • US Food and Drug Administration. Savaysa: Highlights of prescribing information. Available from: www.accessdata.fda.gov/drugsatfda-docs/label/2015/206316lbl.pdf. [Last accessed 12 September 2015]
    • Savaysa: Highlights of Prescribing Information
  • 25
    • 84925342906 scopus 로고    scopus 로고
    • Global assays and the management of oral anticoagulation
    • Brinkman HJ. Global assays and the management of oral anticoagulation. Thromb J 2015; 13: 9
    • (2015) Thromb J , vol.13 , pp. 9
    • Brinkman, H.J.1
  • 26
    • 33644837972 scopus 로고    scopus 로고
    • Coagulation assays
    • Bates SM, Weitz JI. Coagulation assays. Circulation 2005; 112 (4): e53-60
    • (2005) Circulation , vol.112 , Issue.4 , pp. e53-60
    • Bates, S.M.1    Weitz, J.I.2
  • 27
    • 34548031359 scopus 로고    scopus 로고
    • The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
    • Stangier J, Rathgen K, Stahle H, et al. The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br J Clin Pharmacol 2007; 64 (3): 292-303
    • (2007) Br J Clin Pharmacol , vol.64 , Issue.3 , pp. 292-303
    • Stangier, J.1    Rathgen, K.2    Stahle, H.3
  • 28
    • 84860528205 scopus 로고    scopus 로고
    • Impact of dabigatran on a large panel of routine or specific coagulation assays. Laboratory recommendations for monitoring of dabigatran etexilate
    • Douxfils J, Mullier F, Robert S, et al. Impact of dabigatran on a large panel of routine or specific coagulation assays. Laboratory recommendations for monitoring of dabigatran etexilate. Thromb Haemost 2012; 107 (5): 985-97
    • (2012) Thromb Haemost , vol.107 , Issue.5 , pp. 985-997
    • Douxfils, J.1    Mullier, F.2    Robert, S.3
  • 29
    • 84891680866 scopus 로고    scopus 로고
    • Measuring dabigatran concentrations using a chromogenic ecarin clotting time assay
    • Gosselin RC, Dwyre DM, Dager WE. Measuring dabigatran concentrations using a chromogenic ecarin clotting time assay. Ann Pharmacother 2013; 47 (12): 1635-40
    • (2013) Ann Pharmacother , vol.47 , Issue.12 , pp. 1635-1640
    • Gosselin, R.C.1    Dwyre, D.M.2    Dager, W.E.3
  • 31
    • 84883238313 scopus 로고    scopus 로고
    • Comparison of calibrated dilute thrombin time and aPTT tests with LC-MS/MS for the therapeutic monitoring of patients treated with dabigatran etexilate
    • Douxfils J, Dogne JM, Mullier F, et al. Comparison of calibrated dilute thrombin time and aPTT tests with LC-MS/MS for the therapeutic monitoring of patients treated with dabigatran etexilate. Thromb Haemost 2013; 110 (3): 543-9
    • (2013) Thromb Haemost , vol.110 , Issue.3 , pp. 543-549
    • Douxfils, J.1    Dogne, J.M.2    Mullier, F.3
  • 32
    • 84930187338 scopus 로고    scopus 로고
    • Estimation of dabigatran plasma concentrations in the perioperative setting. An ex vivo study using dedicated coagulation assays
    • Douxfils J, Lessire S, Dincq AS, et al. Estimation of dabigatran plasma concentrations in the perioperative setting. An ex vivo study using dedicated coagulation assays. Thromb Haemost 2015; 113 (4): 862-9
    • (2015) Thromb Haemost , vol.113 , Issue.4 , pp. 862-869
    • Douxfils, J.1    Lessire, S.2    Dincq, A.S.3
  • 33
    • 84881605571 scopus 로고    scopus 로고
    • Performance of coagulation tests in patients on therapeutic doses of dabigatran: A cross-sectional pharmacodynamic study based on peak and trough plasma levels
    • Hawes EM, Deal AM, Funk-Adcock D, et al. Performance of coagulation tests in patients on therapeutic doses of dabigatran: a cross-sectional pharmacodynamic study based on peak and trough plasma levels. J Thromb Haemost 2013; 11 (8): 1493-502
    • (2013) J Thromb Haemost , vol.11 , Issue.8 , pp. 1493-1502
    • Hawes, E.M.1    Deal, A.M.2    Funk-Adcock, D.3
  • 34
    • 84884861345 scopus 로고    scopus 로고
    • Comparison of calibrated chromogenic anti-Xa assay and PT tests with LC-MS/MS for the therapeutic monitoring of patients treated with rivaroxaban
    • Douxfils J, Tamigniau A, Chatelain B, et al. Comparison of calibrated chromogenic anti-Xa assay and PT tests with LC-MS/MS for the therapeutic monitoring of patients treated with rivaroxaban. Thromb Haemost 2013; 110 (4): 723-31
    • (2013) Thromb Haemost , vol.110 , Issue.4 , pp. 723-731
    • Douxfils, J.1    Tamigniau, A.2    Chatelain, B.3
  • 35
    • 84863679656 scopus 로고    scopus 로고
    • Accurate determination of rivaroxaban levels requires different calibrator sets but not addition of antithrombin
    • Mani H, Rohde G, Stratmann G, et al. Accurate determination of rivaroxaban levels requires different calibrator sets but not addition of antithrombin. Thromb Haemost 2012; 108 (1): 191-8
    • (2012) Thromb Haemost , vol.108 , Issue.1 , pp. 191-198
    • Mani, H.1    Rohde, G.2    Stratmann, G.3
  • 36
    • 80052502475 scopus 로고    scopus 로고
    • Chromogenic laboratory assays to measure the factor Xa-inhibiting properties of apixaban-an oral, direct and selective factor Xa inhibitor
    • Becker RC, Yang H, Barrett Y, et al. Chromogenic laboratory assays to measure the factor Xa-inhibiting properties of apixaban-an oral, direct and selective factor Xa inhibitor. J Thromb Thrombolysis 2011; 32 (2): 183-7
    • (2011) J Thromb Thrombolysis , vol.32 , Issue.2 , pp. 183-187
    • Becker, R.C.1    Yang, H.2    Barrett, Y.3
  • 37
    • 84901191606 scopus 로고    scopus 로고
    • Report of the Subcommittee on Control of Anticoagulation on the determination of the anticoagulant effects of apixaban: Communication from the SSC of the ISTH
    • Harenberg J, Du S, Weiss C, et al. Report of the Subcommittee on Control of Anticoagulation on the determination of the anticoagulant effects of apixaban: communication from the SSC of the ISTH. J Thromb Haemost 2014; 12 (5): 801-4
    • (2014) J Thromb Haemost , vol.12 , Issue.5 , pp. 801-804
    • Harenberg, J.1    Du, S.2    Weiss, C.3
  • 38
    • 84862146631 scopus 로고    scopus 로고
    • Report of the Subcommittee of Control of Anticoagulation on the determination of the anticoagulant effects of rivaroxaban
    • Harenberg J, Marx S, Weiss C, et al. Report of the Subcommittee of Control of Anticoagulation on the determination of the anticoagulant effects of rivaroxaban. J Thromb Haemost 2012; 10 (7): 1433-6
    • (2012) J Thromb Haemost , vol.10 , Issue.7 , pp. 1433-1436
    • Harenberg, J.1    Marx, S.2    Weiss, C.3
  • 39
    • 84992382294 scopus 로고    scopus 로고
    • OR 285: Assays to measure direct oral anticoagulants (DOAC) - Data from UK Neqas multicentre studies. Abstracts of the XXV Congress of the International Society on Thrombosis and Haemostasis, June 20-25, 2015
    • Jennings I, Kitchen S, Kitchen DP, et al. OR 285: Assays to measure direct oral anticoagulants (DOAC)-data from UK Neqas multicentre studies. Abstracts of the XXV Congress of the International Society on Thrombosis and Haemostasis, June 20-25, 2015. J Thromb Haemost 2015; 13 (Suppl 2): 1-997
    • (2015) J Thromb Haemost , vol.13 , pp. 1-997
    • Jennings, I.1    Kitchen, S.2    Kitchen, D.P.3
  • 40
    • 84931567140 scopus 로고    scopus 로고
    • Direct Oral Anticoagulants (DOACs) in the Laboratory: 2015 Review
    • Adcock DM, Gosselin R. Direct Oral Anticoagulants (DOACs) in the Laboratory: 2015 Review. Thromb Res 2015; 136 (1): 7-12
    • (2015) Thromb Res , vol.136 , Issue.1 , pp. 7-12
    • Adcock, D.M.1    Gosselin, R.2
  • 41
    • 84893160985 scopus 로고    scopus 로고
    • The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: The RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy)
    • Reilly PA, Lehr T, Haertter S, et al. The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy). J Am Coll Cardiol 2014; 63 (4): 321-8
    • (2014) J Am Coll Cardiol , vol.63 , Issue.4 , pp. 321-328
    • Reilly, P.A.1    Lehr, T.2    Haertter, S.3
  • 42
    • 84880798450 scopus 로고    scopus 로고
    • The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma samples
    • Hapgood G, Butler J, Malan E, et al. The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma samples. Thromb Haemost 2013; 110 (2): 308-15
    • (2013) Thromb Haemost , vol.110 , Issue.2 , pp. 308-315
    • Hapgood, G.1    Butler, J.2    Malan, E.3
  • 43
    • 84940440202 scopus 로고    scopus 로고
    • Is Thrombin time useful for the assessment of dabigatran concentrations? An in vitro and ex vivo study
    • Lessire S, Douxfils J, Baudar J, et al. Is Thrombin time useful for the assessment of dabigatran concentrations? An in vitro and ex vivo study. Thromb Res 2015; 136 (3): 693-6
    • (2015) Thromb Res , vol.136 , Issue.3 , pp. 693-696
    • Lessire, S.1    Douxfils, J.2    Baudar, J.3
  • 44
    • 79851482951 scopus 로고    scopus 로고
    • Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays
    • Lindahl TL, Baghaei F, Blixter IF, et al. Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays. Thromb Haemost 2011; 105 (2): 371-8
    • (2011) Thromb Haemost , vol.105 , Issue.2 , pp. 371-378
    • Lindahl, T.L.1    Baghaei, F.2    Blixter, I.F.3
  • 45
    • 33751252564 scopus 로고    scopus 로고
    • Monitoring unfractionated heparin with the aPTT: Time for a fresh look
    • Eikelboom JW, Hirsh J. Monitoring unfractionated heparin with the aPTT: time for a fresh look. Thromb Haemost 2006; 96 (5): 547-52
    • (2006) Thromb Haemost , vol.96 , Issue.5 , pp. 547-552
    • Eikelboom, J.W.1    Hirsh, J.2
  • 46
    • 10844233894 scopus 로고    scopus 로고
    • The ecarin clotting time, a universal method to quantify direct thrombin inhibitors
    • Nowak G. The ecarin clotting time, a universal method to quantify direct thrombin inhibitors. Pathophysiol Haemost Thromb 2003; 33 (4): 173-83
    • (2003) Pathophysiol Haemost Thromb , vol.33 , Issue.4 , pp. 173-183
    • Nowak, G.1
  • 47
    • 10844269522 scopus 로고    scopus 로고
    • Ecarin chromogenic assay-A new method for quantitative determination of direct thrombin inhibitors like hirudin
    • Lange U, Nowak G, Bucha E. Ecarin chromogenic assay-a new method for quantitative determination of direct thrombin inhibitors like hirudin. Pathophysiol Haemost Thromb 2003; 33 (4): 184-91
    • (2003) Pathophysiol Haemost Thromb , vol.33 , Issue.4 , pp. 184-191
    • Lange, U.1    Nowak, G.2    Bucha, E.3
  • 48
    • 79955432850 scopus 로고    scopus 로고
    • Last accessed 3 August 2015
    • European Medicines Agency. Pradaxa, summary of product characteristics. 2014. Available from: www.ema.europa.eu/docs/en-GB/document-library/EPAR-Product-Information/human/000829/WC500041059.pdf. [Last accessed 3 August 2015]
    • (2014) Pradaxa, Summary of Product Characteristics
  • 49
    • 84857014060 scopus 로고    scopus 로고
    • Determination of dabigatran in human plasma samples
    • Harenberg J, Giese C, Marx S, Kramer R. Determination of dabigatran in human plasma samples. Semin Thromb Hemost 2012; 38 (1): 16-22
    • (2012) Semin Thromb Hemost , vol.38 , Issue.1 , pp. 16-22
    • Harenberg, J.1    Giese, C.2    Marx, S.3    Kramer, R.4
  • 50
    • 84902590576 scopus 로고    scopus 로고
    • Comparison of the aPTT with alternative tests for monitoring direct thrombin inhibitors in patient samples
    • Lind SE, Boyle ME, Fisher S, et al. Comparison of the aPTT with alternative tests for monitoring direct thrombin inhibitors in patient samples. Am J Clin Pathol 2014; 141 (5): 665-74
    • (2014) Am J Clin Pathol , vol.141 , Issue.5 , pp. 665-674
    • Lind, S.E.1    Boyle, M.E.2    Fisher, S.3
  • 51
    • 84928618395 scopus 로고    scopus 로고
    • Does the Russell Viper Venom time test provide a rapid estimation of the intensity of oral anticoagulation? A cohort study
    • Douxfils J, Chatelain B, Hjemdahl P, et al. Does the Russell Viper Venom time test provide a rapid estimation of the intensity of oral anticoagulation? A cohort study. Thromb Res 2015; 135 (5): 852-60
    • (2015) Thromb Res , vol.135 , Issue.5 , pp. 852-860
    • Douxfils, J.1    Chatelain, B.2    Hjemdahl, P.3
  • 52
    • 80052485992 scopus 로고    scopus 로고
    • Rivaroxaban: Population pharmacokinetic analyses in patients treated for acute deep-vein thrombosis and exposure simulations in patients with atrial fibrillation treated for stroke prevention
    • Mueck W, Lensing AW, Agnelli G, et al. Rivaroxaban: population pharmacokinetic analyses in patients treated for acute deep-vein thrombosis and exposure simulations in patients with atrial fibrillation treated for stroke prevention. Clin Pharmacokinet 2011; 50 (10): 675-86
    • (2011) Clin Pharmacokinet , vol.50 , Issue.10 , pp. 675-686
    • Mueck, W.1    Lensing, A.W.2    Agnelli, G.3
  • 53
    • 84870240173 scopus 로고    scopus 로고
    • Assessment of the impact of rivaroxaban on coagulation assays: Laboratory recommendations for the monitoring of rivaroxaban and review of the literature
    • Douxfils J, Mullier F, Loosen C, et al. Assessment of the impact of rivaroxaban on coagulation assays: laboratory recommendations for the monitoring of rivaroxaban and review of the literature. Thromb Res 2012; 130 (6): 956-66
    • (2012) Thromb Res , vol.130 , Issue.6 , pp. 956-966
    • Douxfils, J.1    Mullier, F.2    Loosen, C.3
  • 54
    • 77952044405 scopus 로고    scopus 로고
    • Assessment of laboratory assays to measure rivaroxaban-an oral, direct factor Xa inhibitor
    • Samama MM, Martinoli JL, LeFlem L, et al. Assessment of laboratory assays to measure rivaroxaban-an oral, direct factor Xa inhibitor. Thromb Haemost 2010; 103 (4): 815-25
    • (2010) Thromb Haemost , vol.103 , Issue.4 , pp. 815-825
    • Samama, M.M.1    Martinoli, J.L.2    LeFlem, L.3
  • 55
    • 78650965540 scopus 로고    scopus 로고
    • Effects of the oral, direct factor Xa inhibitor rivaroxaban on commonly used coagulation assays
    • Hillarp A, Baghaei F, Fagerberg Blixter I, et al. Effects of the oral, direct factor Xa inhibitor rivaroxaban on commonly used coagulation assays. J Thromb Haemost 2011; 9 (1): 133-9
    • (2011) J Thromb Haemost , vol.9 , Issue.1 , pp. 133-139
    • Hillarp, A.1    Baghaei, F.2    Fagerberg Blixter, I.3
  • 56
    • 79960068693 scopus 로고    scopus 로고
    • Rivaroxaban differentially influences ex vivo global coagulation assays based on the administration time
    • Mani H, Hesse C, Stratmann G, Lindhoff-Last E. Rivaroxaban differentially influences ex vivo global coagulation assays based on the administration time. Thromb Haemost 2011; 106 (1): 156-64
    • (2011) Thromb Haemost , vol.106 , Issue.1 , pp. 156-164
    • Mani, H.1    Hesse, C.2    Stratmann, G.3    Lindhoff-Last, E.4
  • 57
    • 84938739448 scopus 로고    scopus 로고
    • Anti-coagulation assessment with prothrombin time and anti-Xa assays in real-world patients on treatment with rivaroxaban
    • Konigsbrugge O, Quehenberger P, Belik S, et al. Anti-coagulation assessment with prothrombin time and anti-Xa assays in real-world patients on treatment with rivaroxaban. Ann Hematol 2015; 94 (9): 1463-71
    • (2015) Ann Hematol , vol.94 , Issue.9 , pp. 1463-1471
    • Konigsbrugge, O.1    Quehenberger, P.2    Belik, S.3
  • 58
    • 84914695678 scopus 로고    scopus 로고
    • Comparison of anti-Xa and dilute Russell viper venom time assays in quantifying drug levels in patients on therapeutic doses of rivaroxaban
    • Gosselin RC, Adcock Funk DM, Taylor JM, et al. Comparison of anti-Xa and dilute Russell viper venom time assays in quantifying drug levels in patients on therapeutic doses of rivaroxaban. Arch Pathol Lab Med 2014; 138 (12): 1680-4
    • (2014) Arch Pathol Lab Med , vol.138 , Issue.12 , pp. 1680-1684
    • Gosselin, R.C.1    Adcock Funk, D.M.2    Taylor, J.M.3
  • 59
    • 84976585919 scopus 로고    scopus 로고
    • Last accessed 3 August 2015
    • European Medicines Agency. Apixaban, Summary of Product Characteristics, 2014. Available from: www.ema.europa.eu/docs/en-GB/document-library/EPAR---Product-Information/human/002148/WC500107728.pdf. [Last accessed 3 August 2015]
    • Apixaban, Summary of Product Characteristics, 2014
  • 60
    • 84934780346 scopus 로고    scopus 로고
    • Association rate constants rationalise the pharmacodynamics of apixaban and rivaroxaban
    • Jourdi G, Siguret V, Martin AC, et al. Association rate constants rationalise the pharmacodynamics of apixaban and rivaroxaban. Thromb Haemost 2015; 114 (1): 78-86
    • (2015) Thromb Haemost , vol.114 , Issue.1 , pp. 78-86
    • Jourdi, G.1    Siguret, V.2    Martin, A.C.3
  • 61
    • 84880838834 scopus 로고    scopus 로고
    • Impact of apixaban on routine and specific coagulation assays: A practical laboratory guide
    • Douxfils J, Chatelain C, Chatelain B, et al. Impact of apixaban on routine and specific coagulation assays: a practical laboratory guide. Thromb Haemost 2013; 110 (2): 283-94
    • (2013) Thromb Haemost , vol.110 , Issue.2 , pp. 283-294
    • Douxfils, J.1    Chatelain, C.2    Chatelain, B.3
  • 62
    • 84920262449 scopus 로고    scopus 로고
    • Comparison of the effects of apixaban and rivaroxaban on prothrombin and activated partial thromboplastin times using various reagents
    • Dale BJ, Ginsberg JS, Johnston M, et al. Comparison of the effects of apixaban and rivaroxaban on prothrombin and activated partial thromboplastin times using various reagents. J Thromb Haemost 2014; 12 (11): 1810-15
    • (2014) J Thromb Haemost , vol.12 , Issue.11 , pp. 1810-1815
    • Dale, B.J.1    Ginsberg, J.S.2    Johnston, M.3
  • 63
    • 84893185400 scopus 로고    scopus 로고
    • Assessment of apixaban plasma levels by laboratory tests: Suitability of three anti-Xa assays. A multicentre French GEHT study
    • Gouin-Thibault I, Flaujac C, Delavenne X, et al. Assessment of apixaban plasma levels by laboratory tests: suitability of three anti-Xa assays. A multicentre French GEHT study. Thromb Haemost 2014; 111 (2): 240-8
    • (2014) Thromb Haemost , vol.111 , Issue.2 , pp. 240-248
    • Gouin-Thibault, I.1    Flaujac, C.2    Delavenne, X.3
  • 64
    • 84875933929 scopus 로고    scopus 로고
    • Testing for new oral anticoagulants with LA-resistant Russells viper venom reagents. An in vitro study
    • Exner T, Ellwood L, Rubie J, Barancewicz A. Testing for new oral anticoagulants with LA-resistant Russells viper venom reagents. An in vitro study. Thromb Haemost 2013; 109 (4): 762-5
    • (2013) Thromb Haemost , vol.109 , Issue.4 , pp. 762-765
    • Exner, T.1    Ellwood, L.2    Rubie, J.3    Barancewicz, A.4
  • 65
    • 84934289246 scopus 로고    scopus 로고
    • Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: An analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial
    • Ruff CT, Giugliano RP, Braunwald E, et al. Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial. Lancet 2015; 385 (9984): 2288-95
    • (2015) Lancet , vol.385 , Issue.9984 , pp. 2288-2295
    • Ruff, C.T.1    Giugliano, R.P.2    Braunwald, E.3
  • 66
    • 77954361232 scopus 로고    scopus 로고
    • Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation
    • Weitz JI, Connolly SJ, Patel I, et al. Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation. Thromb Haemost 2010; 104 (3): 633-41
    • (2010) Thromb Haemost , vol.104 , Issue.3 , pp. 633-641
    • Weitz, J.I.1    Connolly, S.J.2    Patel, I.3
  • 67
    • 84925493502 scopus 로고    scopus 로고
    • Laboratory measurement of the anticoagulant activity of edoxaban: A systematic review
    • Cuker A, Husseinzadeh H. Laboratory measurement of the anticoagulant activity of edoxaban: a systematic review. J Thromb Thrombolysis 2015; 39 (3): 288-94
    • (2015) J Thromb Thrombolysis , vol.39 , Issue.3 , pp. 288-294
    • Cuker, A.1    Husseinzadeh, H.2
  • 68
    • 84858335249 scopus 로고    scopus 로고
    • In vitro study of the anticoagulant effects of edoxaban and its effect on thrombin generation in comparison to fondaparinux
    • Samama MM, Mendell J, Guinet C, et al. In vitro study of the anticoagulant effects of edoxaban and its effect on thrombin generation in comparison to fondaparinux. Thromb Res 2012; 129 (4): e77-82
    • (2012) Thromb Res , vol.129 , Issue.4 , pp. e77-82
    • Samama, M.M.1    Mendell, J.2    Guinet, C.3


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