Outcomes of prognostic disclosure: Associations with prognostic understanding, distress, and relationship with physician among patients with advanced cancer

Journal of Clinical Oncology

Volumn 33, Issue 32, 2015, Pages 3809-3816

  Enzinger, Andrea C ^a   Zhang, Baohui ^b   Schrag, Deborah ^a   Prigerson, Holly G ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT;

ADULT; ADVANCED CANCER; ANXIETY; ARTICLE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER PALLIATIVE THERAPY; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; DISEASE ASSOCIATION; DISTRESS SYNDROME; DOCTOR PATIENT RELATION; FEMALE; FOLLOW UP; HUMAN; LIVING WILL; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OBSERVATIONAL STUDY; ONCOLOGIST; PATIENT CARE; PATIENT COMFORT; PRIORITY JOURNAL; PROSPECTIVE STUDY; SADNESS; SOLID TUMOR; TERMINAL CARE; AGED; CLINICAL TRIAL; COMPREHENSION; EMOTION; ETIOLOGY; INTERPERSONAL COMMUNICATION; LIFE EXPECTANCY; MENTAL STRESS; MULTICENTER STUDY; NEOPLASMS; ODDS RATIO; PATIENT PREFERENCE; PROGNOSIS;

ADULT; ADVANCE DIRECTIVES; AGED; COMPREHENSION; EMOTIONS; FEMALE; HUMANS; LIFE EXPECTANCY; MALE; MIDDLE AGED; NEOPLASMS; ODDS RATIO; PATIENT PREFERENCE; PHYSICIAN-PATIENT RELATIONS; PROGNOSIS; STRESS, PSYCHOLOGICAL; TERMINAL CARE; TRUTH DISCLOSURE;

EID: 84947422588     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2015.61.9239     Document Type: Article

References (59)

1. Back AL, Arnold R, Tulsky JA: Mastering Communication With Seriously Ill Patients: Balancing Honesty With Empathy and Hope. New York, NY, Cambridge University Press, 2009
2. Clayton JM, Butow PN, Arnold RM, et al: Discussing end-of-life issues with terminally ill cancer patients and their carers: A qualitative study. Support Care Cancer 13:589-599, 2005
3. Weeks JC, Cook EF, O'Day SJ, et al: Relationship between cancer patients' predictions of prognosis and their treatment preferences. JAMA 279:1709-1714, 1998
4. Eidinger RN, Schapira DV: Cancer patients' insight into their treatment, prognosis, and unconventional therapies. Cancer 53:2736-2740, 1984
5. Gabrijel S, Grize L, Helfenstein E, et al: Receiving the diagnosis of lung cancer: Patient recall of information and satisfaction with physician communication. J Clin Oncol 26:297-302, 2008
6. Gattellari M, Butow PN, Tattersall MH, et al: Misunderstanding in cancer patients: Why shoot the messenger? Ann Oncol 10:39-46, 1999
7. Meropol NJ, Weinfurt KP, Burnett CB, et al: Perceptions of patients and physicians regarding phase I cancer clinical trials: Implications for physician-patient communication. J Clin Oncol 21:2589-2596, 2003
8. Weeks JC, Catalano PJ, Cronin A, et al: Patients' expectations about effects of chemotherapy for advanced cancer. N Engl J Med 367:1616-1625, 2012
9. Lennes IT, Temel JS, Hoedt C, et al: Predictors of newly diagnosed cancer patients' understanding of the goals of their care at initiation of chemotherapy. Cancer 119:691-699, 2013
10. Temel JS, Greer JA, Admane S, et al: Longitudinal perceptions of prognosis and goals of therapy in patients with metastatic non-small-cell lung cancer: Results of a randomized study of early palliative care. J Clin Oncol 29:2319-2326, 2011
11. Weinfurt KP, Seils DM, Lin L, et al: Research participants' high expectations of benefit in earlyphase oncology trials: Are we asking the right question? J Clin Oncol 30:4396-4400, 2012
12. Quirt CF, Mackillop WJ, Ginsburg AD, et al: Do doctors know when their patients don't? A survey of doctor-patient communication in lung cancer. Lung Cancer 18:1-20, 1997
13. Wolfe J, Klar N, Grier HE, et al: Understanding of prognosis among parents of children who died of cancer: Impact on treatment goals and integration of palliative care. JAMA 284:2469-2475, 2000
14. Mackillop WJ, Stewart WE, Ginsburg AD, et al: Cancer patients' perceptions of their disease and its treatment. Br J Cancer 58:355-358, 1988
15. Anderson WG, Chase R, Pantilat SZ, et al: Code status discussions between attending hospitalist physicians and medical patients at hospital admission. J Gen Intern Med 26:359-366, 2011
16. The AM, Hak T, Koëter G, et al: Collusion in doctor-patient communication about imminent death: An ethnographic study. BMJ 321:1376-1381, 2000
17. Daugherty CK, Hlubocky FJ: What are terminally ill cancer patients told about their expected deaths? A study of cancer physicians' self-reports of prognosis disclosure J Clin Oncol 26:5988-5993, 2008
18. Keating NL, Landrum MB, Rogers SO Jr, et al: Physician factors associated with discussions about end-of-life care. Cancer 116:998-1006, 2010
19. Gordon EJ, Daugherty CK: "Hitting you over the head": Oncologists' disclosure of prognosis to advanced cancer patients. Bioethics 17:142-168, 2003
20. Hancock K, Clayton JM, Parker SM, et al: Truth-telling in discussing prognosis in advanced life-limiting illnesses: A systematic review. Palliat Med 21:507-517, 2007
21. Christakis NA, Iwashyna TJ: Attitude and self-reported practice regarding prognostication in a national sample of internists. Arch Intern Med 158:2389-2395, 1998
22. Lamont EB, Christakis NA: Prognostic disclosure to patients with cancer near the end of life. Ann Intern Med 134:1096-1105, 2001
23. Selby D, Chakraborty A, Lilien T, et al: Clinician accuracy when estimating survival duration: The role of the patient's performance status and time-based prognostic categories. J Pain Symptom Manage 42:578-588, 2011
24. Rogg L, Aasland OG, Graugaard PK, et al: Direct communication, the unquestionable ideal? Oncologists' accounts of communication of bleak prognoses. Psychooncology 19:1221-1228, 2010
25. Hagerty RG, Butow PN, Ellis PM, et al: Communicating with realism and hope: Incurable cancer patients' views on the disclosure of prognosis. J Clin Oncol 23:1278-1288, 2005
26. Mack JW, Wolfe J, Cook EF, et al: Hope and prognostic disclosure. J Clin Oncol 25:5636-5642, 2007
27. Baile WF, Lenzi R, Parker PA, et al: Oncologists' attitudes toward and practices in giving bad news: An exploratory study. J Clin Oncol 20:2189-2196, 2002
28. Parker SM, Clayton JM, Hancock K, et al: A systematic review of prognostic/end-of-life communication with adults in the advanced stages of a life-limiting illness: Patient/caregiver preferences for the content, style, and timing of information. J Pain Symptom Manage 34:81-93, 2007
29. Innes S, Payne S: Advanced cancer patients' prognostic information preferences: A review. Palliat Med 23:29-39, 2009
30. Yun YH, Kwon YC, Lee MK, et al: Experiences and attitudes of patients with terminal cancer and their family caregivers toward the disclosure of terminal illness. J Clin Oncol 28:1950-1957, 2010
31. Barnett MM: Does it hurt to know the worst? Psychological morbidity, information preferences and understanding of prognosis in patients with advanced cancer. Psychooncology 15:44-55, 2006
32. Hagerty RG, Butow PN, Ellis PA, et al: Cancer patient preferences for communication of prognosis in the metastatic setting. J Clin Oncol 22:1721-1730, 2004
33. Elkin EB, Kim SH, Casper ES, et al: Desire for information and involvement in treatment decisions: Elderly cancer patients' preferences and their physicians' perceptions. J Clin Oncol 25:5275-5280, 2007
34. Fried TR, Bradley EH, O'Leary J: Prognosis communication in serious illness: Perceptions of older patients, caregivers, and clinicians. J Am Geriatr Soc 51:1398-1403, 2003
35. Kaplowitz SA, Campo S, Chiu WT: Cancer patients' desires for communication of prognosis information. Health Commun 14:221-241, 2002
36. Boyd EA, Lo B, Evans LR, et al: "It's not just what the doctor tells me:" Factors that influence surrogate decision-makers' perceptions of prognosis. Crit Care Med 38:1270-1275, 2010
37. Liu PH, Landrum MB, Weeks JC, et al: Physicians' propensity to discuss prognosis is associated with patients' awareness of prognosis for metastatic cancers. J Palliat Med 17:673-682, 2014
38. Pfeiffer E: A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. J Am Geriatr Soc 23:433-441, 1975
39. Charlson ME, Pompei P, Ales KL, et al: A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis 40:373-383, 1987
40. Karnofsky DA: Determining the extent of the cancer and clinical planning for cure. Cancer 22:730-734, 1968
41. Loggers ET, Maciejewski PK, Paulk E, et al: Racial differences in predictors of intensive end-oflife care in patients with advanced cancer. J Clin Oncol 27:5559-5564, 2009
42. Pargament KI, Koenig HG, Perez LM: The many methods of religious coping: Development and initial validation of the RCOPE. J Clin Psychol 56:519-543, 2000
43. Phelps AC, Maciejewski PK, Nilsson M, et al: Religious coping and use of intensive life-prolonging care near death in patients with advanced cancer. JAMA 301:1140-1147, 2009
44. Fetzer Institute: Multidimensional Measure of Religiousness/Spirituality for use in health research: A report of the Fetzer Institute/National Institute on Aging Working Group. http://fetzer.org/sites/default/files/images/resources/attachment/[current-date:tiny]/Multidimensional-Measurement-of-Religousness-Spirituality.pdf
45. Cohen SR, Mount BM, Strobel MG, et al: The McGill Quality of Life Questionnaire: A measure of quality of life appropriate for people with advanced disease-A preliminary study of validity and acceptability. Palliat Med 9:207-219, 1995
46. Wright AA, Zhang B, Ray A, et al: Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment. JAMA 300:1665-1673, 2008
47. First M, Spitzer R, Gibbon M, et al: Structured Clinical Interview for the DSM-IV Axis I Disorders: Patient Edition (SCID-I/P; version 2.0). New York, NY, New York State Psychiatric Institute, 1995
48. Endicott J: Measurement of depression in patients with cancer. Cancer 53:2243-2249, 1984(suppl)
49. Mack JW, Block SD, Nilsson M, et al: Measuring therapeutic alliance between oncologists and patients with advanced cancer: The Human Connection Scale. Cancer 115:3302-3311, 2009
50. Zhang B, Nilsson ME, Prigerson HG: Factors important to patients' quality of life at the end of life. Arch Intern Med 172:1133-1142, 2012
51. Chen C: A finite smoothing algorithm for quantile regression. J Comput Graph Stat 16:136-164, 2007
52. Zhang J, Yu KF: What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA 280:1690-1691, 1998
53. Walczak A, Henselmans I, Tattersall MH, et al: A qualitative analysis of responses to a question prompt list and prognosis and end-of-life care discussion prompts delivered in a communication support program. Psychooncology 24:287-293, 2015
54. Hancock K, Clayton JM, Parker SM, et al: Discrepant perceptions about end-of-life communication: A systematic review. J Pain Symptom Manage 34:190-200, 2007
55. Jenkins V, Solis-Trapala I, Langridge C, et al: What oncologists believe they said and what patients believe they heard: An analysis of phase I trial discussions. J Clin Oncol 29:61-68, 2011
56. Audrey S, Abel J, Blazeby JM, et al: What oncologists tell patients about survival benefits of palliative chemotherapy and implications for informed consent: Qualitative study. BMJ 337:a752, 2008
57. Tanco K, Rhondali W, Perez-Cruz P, et al: Patient perception of physician compassion after a more optimistic vs a less optimistic message: A randomized clinical trial. JAMA Oncol 1:176-183, 2015
58. Silveira MJ, Kim SY, Langa KM: Advance directives and outcomes of surrogate decision making before death. N Engl J Med 362:1211-1218, 2010
59. Steinhauser KE, Christakis NA, Clipp EC, et al: Factors considered important at the end of life by patients, family, physicians, and other care providers. JAMA 284:2476-2482, 2000