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Volumn 41, Issue , 2015, Pages 19S-31S

Dipeptidyl Peptidase-4 Inhibitors in Diverse Patient Populations With Type 2 Diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; DIPEPTIDYL PEPTIDASE IV INHIBITOR; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; INCRETIN; INSULIN; METFORMIN;

EID: 84947418130     PISSN: 01457217     EISSN: 15546063     Source Type: Journal    
DOI: 10.1177/0145721715609420     Document Type: Article
Times cited : (6)

References (92)
  • 1
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • Drucker DJ. The biology of incretin hormones. Cell Metab. 2006;3(3):153-165.
    • (2006) Cell Metab , vol.3 , Issue.3 , pp. 153-165
    • Drucker, D.J.1
  • 2
    • 9444244529 scopus 로고    scopus 로고
    • Gastric inhibitory polypeptide and glucagon-like peptide-1 in the pathogenesis of type 2 diabetes
    • Nauck MA, Baller B, Meier JJ. Gastric inhibitory polypeptide and glucagon-like peptide-1 in the pathogenesis of type 2 diabetes. Diabetes. 2004;53(suppl 3):S190-S196.
    • (2004) Diabetes , vol.53 , pp. S190-S196
    • Nauck, M.A.1    Baller, B.2    Meier, J.J.3
  • 3
  • 4
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet. 2006;368(9548):1696-1705.
    • (2006) Lancet , vol.368 , Issue.9548 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 5
    • 64649104158 scopus 로고    scopus 로고
    • Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus
    • DeFronzo RA. Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes. 2009;58(4):773-795.
    • (2009) Diabetes , vol.58 , Issue.4 , pp. 773-795
    • DeFronzo, R.A.1
  • 6
    • 84993728226 scopus 로고    scopus 로고
    • San Diego, CA: Amylin Pharmaceuticals Inc.
    • BydureonTM (exenatide extended-release for injectable suspension) [package insert]. San Diego, CA: Amylin Pharmaceuticals Inc.; 2012.
    • (2012)
  • 7
    • 84993722506 scopus 로고    scopus 로고
    • Wilmington, DE: AstraZeneca
    • Byetta® (exenatide injection) [package insert]. Wilmington, DE: AstraZeneca; 2014.
    • (2014)
  • 8
    • 84993815075 scopus 로고    scopus 로고
    • Wilmington, DE: GlaxoSmithKline LLC
    • TanzeumTM (albiglutide for injection) [package insert]. Wilmington, DE: GlaxoSmithKline LLC; 2014.
    • (2014)
  • 9
    • 84993815061 scopus 로고    scopus 로고
    • Indianapolis, IN: Eli Lilly & Co
    • TrulicityTM (dulaglutide injection) [package insert]. Indianapolis, IN: Eli Lilly & Co; 2014.
    • (2014)
  • 10
    • 84993775215 scopus 로고    scopus 로고
    • Princeton, NJ: Novo Nordisk Inc
    • Victoza® (liraglutide [rDNA origin] injection) [package insert]. Princeton, NJ: Novo Nordisk Inc; 2012.
    • (2012)
  • 11
    • 84993822711 scopus 로고    scopus 로고
    • Ridgefield, CT: Boehringer Ingelheim
    • Tradjenta® (linagliptin) [package insert]. Ridgefield, CT: Boehringer Ingelheim; 2014.
    • (2014)
  • 12
    • 84993775213 scopus 로고    scopus 로고
    • Whitehouse Station, NJ: Merck & Co Inc
    • Januvia® (sitagliptin) [package insert]. Whitehouse Station, NJ: Merck & Co Inc; 2014.
    • (2014)
  • 13
    • 84993822722 scopus 로고    scopus 로고
    • Wilmington, DE: AstraZeneca
    • Onglyza® (saxagliptin) [package insert]. Wilmington, DE: AstraZeneca; 2014.
    • (2014)
  • 14
    • 84993751848 scopus 로고    scopus 로고
    • Deerfield, IL: Takeda Pharmaceuticals America Inc
    • Nesina® (alogliptin) [package insert]. Deerfield, IL: Takeda Pharmaceuticals America Inc; 2013.
    • (2013)
  • 15
    • 17844407465 scopus 로고    scopus 로고
    • The therapeutic actions of DPP-IV inhibition are not mediated by glucagon-like peptide-1
    • Nauck MA, El-Ouaghlidi A. The therapeutic actions of DPP-IV inhibition are not mediated by glucagon-like peptide-1. Diabetologia. 2005;48(4):608-611.
    • (2005) Diabetologia , vol.48 , Issue.4 , pp. 608-611
    • Nauck, M.A.1    El-Ouaghlidi, A.2
  • 16
    • 84928197116 scopus 로고    scopus 로고
    • Standards of medical care in diabetes: 2015
    • American Diabetes Association. Standards of medical care in diabetes: 2015. Diabetes Care. 2015;38(suppl 1):S41-S48.
    • (2015) Diabetes Care , vol.38 , pp. S41-S48
  • 17
    • 84928197116 scopus 로고    scopus 로고
    • Standards of medical care in diabetes: 2015
    • American Diabetes Association. Standards of medical care in diabetes: 2015. Diabetes Care. 2015;38(suppl 1):S33-S40.
    • (2015) Diabetes Care , vol.38 , pp. S33-S40
  • 18
    • 84919999219 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach. Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • Inzucchi SE, Bergenstal RM, Buse JB et al. Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach. Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2015;38(1):140-149.
    • (2015) Diabetes Care , vol.38 , Issue.1 , pp. 140-149
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 19
    • 0036724721 scopus 로고    scopus 로고
    • Long-term treatment with dipeptidyl peptidase IV inhibitor improves hepatic and peripheral insulin sensitivity in the VDF Zucker rat: a euglycemic-hyperinsulinemic clamp study
    • Pospisilik JA, Stafford SG, Demuth HU, McIntosh CH, Pederson RA. Long-term treatment with dipeptidyl peptidase IV inhibitor improves hepatic and peripheral insulin sensitivity in the VDF Zucker rat: a euglycemic-hyperinsulinemic clamp study. Diabetes. 2002;51(9):2677-2683.
    • (2002) Diabetes , vol.51 , Issue.9 , pp. 2677-2683
    • Pospisilik, J.A.1    Stafford, S.G.2    Demuth, H.U.3    McIntosh, C.H.4    Pederson, R.A.5
  • 20
    • 18144436363 scopus 로고    scopus 로고
    • Reducing insulin resistance with metformin: the evidence today
    • Giannarelli R, Aragona M, Coppelli A, Del Prato S. Reducing insulin resistance with metformin: the evidence today. Diabetes Metab. 2003;29(4, pt 2):6S28-6S35.
    • (2003) Diabetes Metab , vol.29 , pp. 6S28-6S35
    • Giannarelli, R.1    Aragona, M.2    Coppelli, A.3    Del Prato, S.4
  • 21
    • 84879944944 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists’ comprehensive diabetes management algorithm 2013 consensus statement
    • Garber AJ, Abrahamson MJ, Barzilay JI et al. American Association of Clinical Endocrinologists’ comprehensive diabetes management algorithm 2013 consensus statement. Endocr Pract. 2013;19(suppl 2):1-48.
    • (2013) Endocr Pract , vol.19 , pp. 1-48
    • Garber, A.J.1    Abrahamson, M.J.2    Barzilay, J.I.3
  • 22
    • 84905821643 scopus 로고    scopus 로고
    • Comparative effectiveness of dipeptidylpeptidase-4 inhibitors in type 2 diabetes: a systematic review and mixed treatment comparison
    • Craddy P, Palin HJ, Johnson KI. Comparative effectiveness of dipeptidylpeptidase-4 inhibitors in type 2 diabetes: a systematic review and mixed treatment comparison. Diabetes Ther. 2014;5(1):1-41.
    • (2014) Diabetes Ther , vol.5 , Issue.1 , pp. 1-41
    • Craddy, P.1    Palin, H.J.2    Johnson, K.I.3
  • 23
    • 33845476757 scopus 로고    scopus 로고
    • Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone
    • Charbonnel B, Karasik A, Liu J, Wu M, Meininger G; Sitagliptin Study Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone. Diabetes Care. 2006;29(12):2638-2643.
    • (2006) Diabetes Care , vol.29 , Issue.12 , pp. 2638-2643
    • Charbonnel, B.1    Karasik, A.2    Liu, J.3    Wu, M.4    Meininger, G.5
  • 24
    • 69549135336 scopus 로고    scopus 로고
    • The efficacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled type 2 diabetes with metformin alone
    • DeFronzo RA, Hissa MN, Garber AJ et al. The efficacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled type 2 diabetes with metformin alone. Diabetes Care. 2009;32(9):1649-1655.
    • (2009) Diabetes Care , vol.32 , Issue.9 , pp. 1649-1655
    • DeFronzo, R.A.1    Hissa, M.N.2    Garber, A.J.3
  • 25
    • 57649225147 scopus 로고    scopus 로고
    • Efficacy and safety of adding the dipeptidyl peptidase-4 inhibitor alogliptin to metformin therapy in patients with type 2 diabetes inadequately controlled with metformin monotherapy: a multicentre, randomised, double-blind, placebo-controlled study
    • Nauck MA, Ellis GC, Fleck PR, Wilson CA, Mekki Q. Efficacy and safety of adding the dipeptidyl peptidase-4 inhibitor alogliptin to metformin therapy in patients with type 2 diabetes inadequately controlled with metformin monotherapy: a multicentre, randomised, double-blind, placebo-controlled study. Int J Clin Pract. 2009;63(1):46-55.
    • (2009) Int J Clin Pract , vol.63 , Issue.1 , pp. 46-55
    • Nauck, M.A.1    Ellis, G.C.2    Fleck, P.R.3    Wilson, C.A.4    Mekki, Q.5
  • 26
    • 78649691630 scopus 로고    scopus 로고
    • Safety and efficacy of linagliptin as add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study
    • Taskinen MR, Rosenstock J, Tamminen I et al. Safety and efficacy of linagliptin as add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study. Diabetes Obes Metab. 2011;13(1):65-74.
    • (2011) Diabetes Obes Metab , vol.13 , Issue.1 , pp. 65-74
    • Taskinen, M.R.1    Rosenstock, J.2    Tamminen, I.3
  • 27
    • 81255160603 scopus 로고    scopus 로고
    • Efficacy and safety of saxagliptin added to metformin in Asian people with type 2 diabetes mellitus: a randomized controlled trial
    • Yang W, Pan CY, Tou C, Zhao J, Gause-Nilsson I. Efficacy and safety of saxagliptin added to metformin in Asian people with type 2 diabetes mellitus: a randomized controlled trial. Diabetes Res Clin Pract. 2011;94(2):217-224.
    • (2011) Diabetes Res Clin Pract , vol.94 , Issue.2 , pp. 217-224
    • Yang, W.1    Pan, C.Y.2    Tou, C.3    Zhao, J.4    Gause-Nilsson, I.5
  • 28
    • 68949212458 scopus 로고    scopus 로고
    • Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: a randomised controlled trial
    • Chacra AR, Tan GH, Apanovitch A, Ravichandran S, List J, Chen R. Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: a randomised controlled trial. Int J Clin Pract. 2009;63(9):1395-1406.
    • (2009) Int J Clin Pract , vol.63 , Issue.9 , pp. 1395-1406
    • Chacra, A.R.1    Tan, G.H.2    Apanovitch, A.3    Ravichandran, S.4    List, J.5    Chen, R.6
  • 29
    • 58149335320 scopus 로고    scopus 로고
    • Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin in patients with type 2 diabetes inadequately controlled by glyburide monotherapy
    • Pratley RE, Kipnes MS, Fleck PR, Wilson C, Mekki Q; Alogliptin Study Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin in patients with type 2 diabetes inadequately controlled by glyburide monotherapy. Diabetes Obes Metab. 2009;11(2):167-176.
    • (2009) Diabetes Obes Metab , vol.11 , Issue.2 , pp. 167-176
    • Pratley, R.E.1    Kipnes, M.S.2    Fleck, P.R.3    Wilson, C.4    Mekki, Q.5
  • 30
    • 73149084956 scopus 로고    scopus 로고
    • Saxagliptin added to a thiazolidinedione improves glycemic control in patients with type 2 diabetes and inadequate control on thiazolidinedione alone
    • Hollander P, Li J, Allen E, Chen R; CV181-013 Investigators. Saxagliptin added to a thiazolidinedione improves glycemic control in patients with type 2 diabetes and inadequate control on thiazolidinedione alone. J Clin Endocrinol Metab. 2009;94(12):4810-4819.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.12 , pp. 4810-4819
    • Hollander, P.1    Li, J.2    Allen, E.3    Chen, R.4
  • 31
    • 33751557143 scopus 로고    scopus 로고
    • Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study
    • Rosenstock J, Brazg R, Andryuk PJ, Lu K, Stein P; Sitagliptin Study Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Clin Ther. 2006;28(10):1556-1568.
    • (2006) Clin Ther , vol.28 , Issue.10 , pp. 1556-1568
    • Rosenstock, J.1    Brazg, R.2    Andryuk, P.J.3    Lu, K.4    Stein, P.5
  • 32
    • 84864757433 scopus 로고    scopus 로고
    • 2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, non-inferiority trial
    • Gallwitz B, Rosenstock J, Rauch T et al. 2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, non-inferiority trial. Lancet. 2012;380(9840):475-483.
    • (2012) Lancet , vol.380 , Issue.9840 , pp. 475-483
    • Gallwitz, B.1    Rosenstock, J.2    Rauch, T.3
  • 33
    • 78349292168 scopus 로고    scopus 로고
    • Saxagliptin is non-inferior to glipizide in patients with type 2 diabetes mellitus inadequately controlled on metformin alone: a 52-week randomised controlled trial
    • Goke B, Gallwitz B, Eriksson J, Hellqvist A, Gause-Nilsson I; D1680C00001 Investigators. Saxagliptin is non-inferior to glipizide in patients with type 2 diabetes mellitus inadequately controlled on metformin alone: a 52-week randomised controlled trial. Int J Clin Pract. 2010;64(12):1619-1631.
    • (2010) Int J Clin Pract , vol.64 , Issue.12 , pp. 1619-1631
    • Goke, B.1    Gallwitz, B.2    Eriksson, J.3    Hellqvist, A.4    Gause-Nilsson, I.5
  • 34
    • 33846817233 scopus 로고    scopus 로고
    • Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, double-blind, non-inferiority trial
    • Nauck MA, Meininger G, Sheng D, Terranella L, Stein PP; Sitagliptin Study Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, double-blind, non-inferiority trial. Diabetes Obes Metab. 2007;9(2):194-205.
    • (2007) Diabetes Obes Metab , vol.9 , Issue.2 , pp. 194-205
    • Nauck, M.A.1    Meininger, G.2    Sheng, D.3    Terranella, L.4    Stein, P.P.5
  • 35
    • 84920280347 scopus 로고    scopus 로고
    • Durability of the efficacy and safety of alogliptin compared with glipizide in type 2 diabetes mellitus: a 2-year study
    • Del Prato S, Camisasca R, Wilson C, Fleck P. Durability of the efficacy and safety of alogliptin compared with glipizide in type 2 diabetes mellitus: a 2-year study. Diabetes Obes Metab. 2014;16(12):1239-1246.
    • (2014) Diabetes Obes Metab , vol.16 , Issue.12 , pp. 1239-1246
    • Del Prato, S.1    Camisasca, R.2    Wilson, C.3    Fleck, P.4
  • 36
    • 34547863123 scopus 로고    scopus 로고
    • Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin
    • Hermansen K, Kipnes M, Luo E et al. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin. Diabetes Obes Metab. 2007;9(5):733-745.
    • (2007) Diabetes Obes Metab , vol.9 , Issue.5 , pp. 733-745
    • Hermansen, K.1    Kipnes, M.2    Luo, E.3
  • 37
    • 84898789442 scopus 로고    scopus 로고
    • A randomized controlled trial of the efficacy and safety of saxagliptin as add-on therapy in patients with type 2 diabetes and inadequate glycaemic control on metformin plus a sulphonylurea
    • Moses RG, Kalra S, Brook D et al. A randomized controlled trial of the efficacy and safety of saxagliptin as add-on therapy in patients with type 2 diabetes and inadequate glycaemic control on metformin plus a sulphonylurea. Diabetes Obes Metab. 2014;16(5):443-450.
    • (2014) Diabetes Obes Metab , vol.16 , Issue.5 , pp. 443-450
    • Moses, R.G.1    Kalra, S.2    Brook, D.3
  • 38
    • 80053072352 scopus 로고    scopus 로고
    • Efficacy and safety of linagliptin in persons with type 2 diabetes inadequately controlled by a combination of metformin and sulphonylurea: a 24-week randomized study
    • Owens DR, Swallow R, Dugi KA, Woerle HJ. Efficacy and safety of linagliptin in persons with type 2 diabetes inadequately controlled by a combination of metformin and sulphonylurea: a 24-week randomized study. Diabet Med. 2011;28(11):1352-1361.
    • (2011) Diabet Med , vol.28 , Issue.11 , pp. 1352-1361
    • Owens, D.R.1    Swallow, R.2    Dugi, K.A.3    Woerle, H.J.4
  • 39
    • 84911395565 scopus 로고    scopus 로고
    • Linagliptin improved glycaemic control without weight gain or hypoglycaemia in patients with type 2 diabetes inadequately controlled by a combination of metformin and pioglitazone: a 24-week randomized, double-blind study
    • Bajaj M, Gilman R, Patel S, Kempthorne-Rawson J, Lewis-D'Agostino D, Woerle HJ, Linagliptin improved glycaemic control without weight gain or hypoglycaemia in patients with type 2 diabetes inadequately controlled by a combination of metformin and pioglitazone: a 24-week randomized, double-blind study. Diabet Med. 2014;31(12):1505-1514.
    • (2014) Diabet Med , vol.31 , Issue.12 , pp. 1505-1514
    • Bajaj, M.1    Gilman, R.2    Patel, S.3    Kempthorne-Rawson, J.4    Lewis-D'Agostino, D.5    Woerle, H.J.6
  • 40
    • 80055037047 scopus 로고    scopus 로고
    • Alogliptin as a third oral antidiabetic drug in patients with type 2 diabetes and inadequate glycaemic control on metformin and pioglitazone: a 52-week, randomized, double-blind, active-controlled, parallel-group study
    • Bosi E, Ellis GC, Wilson CA, Fleck PR. Alogliptin as a third oral antidiabetic drug in patients with type 2 diabetes and inadequate glycaemic control on metformin and pioglitazone: a 52-week, randomized, double-blind, active-controlled, parallel-group study. Diabetes Obes Metab. 2011;13(12):1088-1096.
    • (2011) Diabetes Obes Metab , vol.13 , Issue.12 , pp. 1088-1096
    • Bosi, E.1    Ellis, G.C.2    Wilson, C.A.3    Fleck, P.R.4
  • 41
    • 84875221492 scopus 로고    scopus 로고
    • Efficacy and safety of sitagliptin added to ongoing metformin and pioglitazone combination therapy in a randomized, placebo-controlled, 26-week trial in patients with type 2 diabetes
    • Fonseca V, Staels B, Morgan JD 2nd et al. Efficacy and safety of sitagliptin added to ongoing metformin and pioglitazone combination therapy in a randomized, placebo-controlled, 26-week trial in patients with type 2 diabetes. J Diabetes Complications. 2013;27(2):177-183.
    • (2013) J Diabetes Complications , vol.27 , Issue.2 , pp. 177-183
    • Fonseca, V.1    Staels, B.2    Morgan, J.D.3
  • 42
    • 70349314675 scopus 로고    scopus 로고
    • Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin added to pioglitazone in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study
    • Pratley RE, Reusch JE, Fleck PR, Wilson CA, Mekki Q; Alogliptin Study Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin added to pioglitazone in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study. Curr Med Res Opin. 2009;25(10):2361-2371.
    • (2009) Curr Med Res Opin , vol.25 , Issue.10 , pp. 2361-2371
    • Pratley, R.E.1    Reusch, J.E.2    Fleck, P.R.3    Wilson, C.A.4    Mekki, Q.5
  • 43
    • 84859731126 scopus 로고    scopus 로고
    • Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin
    • Barnett AH, Charbonnel B, Donovan M, Fleming D, Chen R. Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin. Curr Med Res Opin. 2012;28(4):513-523.
    • (2012) Curr Med Res Opin , vol.28 , Issue.4 , pp. 513-523
    • Barnett, A.H.1    Charbonnel, B.2    Donovan, M.3    Fleming, D.4    Chen, R.5
  • 44
    • 70450173642 scopus 로고    scopus 로고
    • Alogliptin added to insulin therapy in patients with type 2 diabetes reduces HbA(1C) without causing weight gain or increased hypoglycaemia
    • Rosenstock J, Rendell MS, Gross JL, Fleck PR, Wilson CA, Mekki Q. Alogliptin added to insulin therapy in patients with type 2 diabetes reduces HbA(1C) without causing weight gain or increased hypoglycaemia. Diabetes Obes Metab. 2009;11(12):1145-1152.
    • (2009) Diabetes Obes Metab , vol.11 , Issue.12 , pp. 1145-1152
    • Rosenstock, J.1    Rendell, M.S.2    Gross, J.L.3    Fleck, P.R.4    Wilson, C.A.5    Mekki, Q.6
  • 45
    • 73349119110 scopus 로고    scopus 로고
    • Efficacy and safety of sitagliptin when added to insulin therapy in patients with type 2 diabetes
    • Vilsboll T, Rosenstock J, Yki-Jarvinen H et al. Efficacy and safety of sitagliptin when added to insulin therapy in patients with type 2 diabetes. Diabetes Obes Metab. 2010;12(2):167-177.
    • (2010) Diabetes Obes Metab , vol.12 , Issue.2 , pp. 167-177
    • Vilsboll, T.1    Rosenstock, J.2    Yki-Jarvinen, H.3
  • 46
    • 84889857731 scopus 로고    scopus 로고
    • Effects of adding linagliptin to basal insulin regimen for inadequately controlled type 2 diabetes: a ≥52-week randomized, double-blind study
    • Yki-Jarvinen H, Rosenstock J, Duran-Garcia S et al. Effects of adding linagliptin to basal insulin regimen for inadequately controlled type 2 diabetes: a ≥52-week randomized, double-blind study. Diabetes Care. 2013;36(12):3875-3881.
    • (2013) Diabetes Care , vol.36 , Issue.12 , pp. 3875-3881
    • Yki-Jarvinen, H.1    Rosenstock, J.2    Duran-Garcia, S.3
  • 47
    • 34547660561 scopus 로고    scopus 로고
    • Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes
    • Goldstein BJ, Feinglos MN, Lunceford JK, Johnson J, Williams-Herman DE; Sitagliptin 036 Study Group. Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes. Diabetes Care. 2007;30(8):1979-1987.
    • (2007) Diabetes Care , vol.30 , Issue.8 , pp. 1979-1987
    • Goldstein, B.J.1    Feinglos, M.N.2    Lunceford, J.K.3    Johnson, J.4    Williams-Herman, D.E.5
  • 48
    • 84862813117 scopus 로고    scopus 로고
    • Initial combination of linagliptin and metformin improves glycaemic control in type 2 diabetes: a randomized, double-blind, placebo-controlled study
    • Haak T, Meinicke T, Jones R, Weber S, von Eynatten M, Woerle HJ. Initial combination of linagliptin and metformin improves glycaemic control in type 2 diabetes: a randomized, double-blind, placebo-controlled study. Diabetes Obes Metab. 2012;14(6):565-574.
    • (2012) Diabetes Obes Metab , vol.14 , Issue.6 , pp. 565-574
    • Haak, T.1    Meinicke, T.2    Jones, R.3    Weber, S.4    von Eynatten, M.5    Woerle, H.J.6
  • 49
    • 65549123794 scopus 로고    scopus 로고
    • Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: a randomized controlled trial
    • Jadzinsky M, Pfutzner A, Paz-Pacheco E, Xu Z, Allen E, Chen R. Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: a randomized controlled trial. Diabetes Obes Metab. 2009;11(6):611-622.
    • (2009) Diabetes Obes Metab , vol.11 , Issue.6 , pp. 611-622
    • Jadzinsky, M.1    Pfutzner, A.2    Paz-Pacheco, E.3    Xu, Z.4    Allen, E.5    Chen, R.6
  • 50
    • 84903187359 scopus 로고    scopus 로고
    • Efficacy and safety of initial combination therapy with alogliptin plus metformin versus either as monotherapy in drug-naive patients with type 2 diabetes: a randomized, double-blind, 6-month study
    • Pratley RE, Fleck P, Wilson C. Efficacy and safety of initial combination therapy with alogliptin plus metformin versus either as monotherapy in drug-naive patients with type 2 diabetes: a randomized, double-blind, 6-month study. Diabetes Obes Metab. 2014;16(7):613-621.
    • (2014) Diabetes Obes Metab , vol.16 , Issue.7 , pp. 613-621
    • Pratley, R.E.1    Fleck, P.2    Wilson, C.3
  • 51
    • 79953174825 scopus 로고    scopus 로고
    • Efficacy and safety of initial combination therapy with linagliptin and pioglitazone in patients with inadequately controlled type 2 diabetes: a randomized, double-blind, placebo controlled study
    • Gomis R, Espadero RM, Jones R, Woerle HJ, Dugi KA. Efficacy and safety of initial combination therapy with linagliptin and pioglitazone in patients with inadequately controlled type 2 diabetes: a randomized, double-blind, placebo controlled study. Diabetes Obes Metab. 2011;13(7):653-661.
    • (2011) Diabetes Obes Metab , vol.13 , Issue.7 , pp. 653-661
    • Gomis, R.1    Espadero, R.M.2    Jones, R.3    Woerle, H.J.4    Dugi, K.A.5
  • 52
    • 79951699944 scopus 로고    scopus 로고
    • Initial combination therapy with alogliptin and pioglitazone in drug-naive patients with type 2 diabetes
    • Rosenstock J, Inzucchi SE, Seufert J, Fleck PR, Wilson CA, Mekki Q. Initial combination therapy with alogliptin and pioglitazone in drug-naive patients with type 2 diabetes. Diabetes Care. 2010;33(11):2406-2408.
    • (2010) Diabetes Care , vol.33 , Issue.11 , pp. 2406-2408
    • Rosenstock, J.1    Inzucchi, S.E.2    Seufert, J.3    Fleck, P.R.4    Wilson, C.A.5    Mekki, Q.6
  • 53
    • 84928199102 scopus 로고    scopus 로고
    • Initial combination of empagliflozin and linagliptin in subjects with type 2 diabetes
    • Lewin A, DeFronzo R, Patel S et al. Initial combination of empagliflozin and linagliptin in subjects with type 2 diabetes. Diabetes Care. 2015;38(3):394-402.
    • (2015) Diabetes Care , vol.38 , Issue.3 , pp. 394-402
    • Lewin, A.1    DeFronzo, R.2    Patel, S.3
  • 54
    • 84860711211 scopus 로고    scopus 로고
    • Efficacy and tolerability of the DPP-4 inhibitor alogliptin combined with pioglitazone, in metformin-treated patients with type 2 diabetes
    • DeFronzo RA, Burant CF, Fleck P, Wilson C, Mekki Q, Pratley RE. Efficacy and tolerability of the DPP-4 inhibitor alogliptin combined with pioglitazone, in metformin-treated patients with type 2 diabetes. J Clin Endocrinol Metab. 2012;97(5):1615-1622.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.5 , pp. 1615-1622
    • DeFronzo, R.A.1    Burant, C.F.2    Fleck, P.3    Wilson, C.4    Mekki, Q.5    Pratley, R.E.6
  • 55
    • 84928176749 scopus 로고    scopus 로고
    • Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin
    • DeFronzo RA, Lewin A, Patel S et al. Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin. Diabetes Care. 2015;38(3):384-393.
    • (2015) Diabetes Care , vol.38 , Issue.3 , pp. 384-393
    • DeFronzo, R.A.1    Lewin, A.2    Patel, S.3
  • 56
    • 84928201032 scopus 로고    scopus 로고
    • Dual add-on therapy in type 2 diabetes poorly controlled with metformin monotherapy: a randomized double-blind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin
    • Rosenstock J, Hansen L, Zee P et al. Dual add-on therapy in type 2 diabetes poorly controlled with metformin monotherapy: a randomized double-blind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin. Diabetes Care. 2015;38(3):376-383.
    • (2015) Diabetes Care , vol.38 , Issue.3 , pp. 376-383
    • Rosenstock, J.1    Hansen, L.2    Zee, P.3
  • 57
    • 75649128008 scopus 로고    scopus 로고
    • Efficacy and safety of monotherapy of sitagliptin compared with metformin in patients with type 2 diabetes
    • Aschner P, Katzeff HL, Guo H et al. Efficacy and safety of monotherapy of sitagliptin compared with metformin in patients with type 2 diabetes. Diabetes Obes Metab. 2010;12(3):252-261.
    • (2010) Diabetes Obes Metab , vol.12 , Issue.3 , pp. 252-261
    • Aschner, P.1    Katzeff, H.L.2    Guo, H.3
  • 58
    • 84873263426 scopus 로고    scopus 로고
    • Linagliptin monotherapy in type 2 diabetes patients for whom metformin is inappropriate: an 18-week randomized, double-blind, placebo-controlled phase III trial with a 34-week active-controlled extension
    • Barnett AH, Patel S, Harper R et al. Linagliptin monotherapy in type 2 diabetes patients for whom metformin is inappropriate: an 18-week randomized, double-blind, placebo-controlled phase III trial with a 34-week active-controlled extension. Diabetes Obes Metab. 2012;14(12):1145-1154.
    • (2012) Diabetes Obes Metab , vol.14 , Issue.12 , pp. 1145-1154
    • Barnett, A.H.1    Patel, S.2    Harper, R.3
  • 59
    • 58149171060 scopus 로고    scopus 로고
    • Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin in patients with type 2 diabetes and inadequate glycemic control: a randomized, double-blind, placebo-controlled study
    • DeFronzo RA, Fleck PR, Wilson CA, Mekki Q; Alogliptin Study Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin in patients with type 2 diabetes and inadequate glycemic control: a randomized, double-blind, placebo-controlled study. Diabetes Care. 2008;31(12):2315-2317.
    • (2008) Diabetes Care , vol.31 , Issue.12 , pp. 2315-2317
    • DeFronzo, R.A.1    Fleck, P.R.2    Wilson, C.A.3    Mekki, Q.4
  • 60
    • 70349333861 scopus 로고    scopus 로고
    • Effect of saxagliptin monotherapy in treatment-naive patients with type 2 diabetes
    • Rosenstock J, Aguilar-Salinas C, Klein E et al. Effect of saxagliptin monotherapy in treatment-naive patients with type 2 diabetes. Curr Med Res Opin. 2009;25(10):2401-2411.
    • (2009) Curr Med Res Opin , vol.25 , Issue.10 , pp. 2401-2411
    • Rosenstock, J.1    Aguilar-Salinas, C.2    Klein, E.3
  • 61
    • 84862556665 scopus 로고    scopus 로고
    • FDA drug safety communication: FDA warns that DPP-4 inhibitors for type 2 diabetes may cause severe joint pain
    • Accessed September 25, 2015
    • US Food and Drug Administration. FDA drug safety communication: FDA warns that DPP-4 inhibitors for type 2 diabetes may cause severe joint pain. http://www.fda.gov/Drugs/DrugSafety/ucm459579.htm. Accessed September 25, 2015.
  • 62
    • 84928197116 scopus 로고    scopus 로고
    • Standards of medical care in diabetes: 2015
    • American Diabetes Association. Standards of medical care in diabetes: 2015. Diabetes Care. 2015;38(suppl 1):S49-S57.
    • (2015) Diabetes Care , vol.38 , pp. S49-S57
  • 63
    • 84883765959 scopus 로고    scopus 로고
    • Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
    • Scirica BM, Bhatt DL, Braunwald E et al. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med. 2013;369(14):1317-1326.
    • (2013) N Engl J Med , vol.369 , Issue.14 , pp. 1317-1326
    • Scirica, B.M.1    Bhatt, D.L.2    Braunwald, E.3
  • 64
    • 84883745765 scopus 로고    scopus 로고
    • Alogliptin after acute coronary syndrome in patients with type 2 diabetes
    • White WB, Cannon CP, Heller SR et al. Alogliptin after acute coronary syndrome in patients with type 2 diabetes. N Engl J Med. 2013;369(14):1327-1335.
    • (2013) N Engl J Med , vol.369 , Issue.14 , pp. 1327-1335
    • White, W.B.1    Cannon, C.P.2    Heller, S.R.3
  • 65
    • 84930085787 scopus 로고    scopus 로고
    • Heart failure and mortality outcomes in patients with type 2 diabetes taking alogliptin versus placebo in EXAMINE: a multicentre, randomised, double-blind trial [published online March 10, 2015]
    • Zannad F, Cannon C, Cushman WC et al. Heart failure and mortality outcomes in patients with type 2 diabetes taking alogliptin versus placebo in EXAMINE: a multicentre, randomised, double-blind trial [published online March 10, 2015]. Lancet 2015.
    • (2015) Lancet
    • Zannad, F.1    Cannon, C.2    Cushman, W.C.3
  • 66
    • 84937053742 scopus 로고    scopus 로고
    • Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes
    • Green JB, Bethel MA, Armstrong PW et al. Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2015;373(3):232-242.
    • (2015) N Engl J Med , vol.373 , Issue.3 , pp. 232-242
    • Green, J.B.1    Bethel, M.A.2    Armstrong, P.W.3
  • 67
    • 84879324855 scopus 로고    scopus 로고
    • Cardiovascular outcome trials in type 2 diabetes and the sulphonylurea controversy: rationale for the active-comparator CAROLINA trial
    • Rosenstock J, Marx N, Kahn SE et al. Cardiovascular outcome trials in type 2 diabetes and the sulphonylurea controversy: rationale for the active-comparator CAROLINA trial. Diab Vasc Dis Res. 2013;10(4):289-301.
    • (2013) Diab Vasc Dis Res , vol.10 , Issue.4 , pp. 289-301
    • Rosenstock, J.1    Marx, N.2    Kahn, S.E.3
  • 68
    • 84899866515 scopus 로고    scopus 로고
    • CARMELINA: Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in patients with type 2 diabetes mellitus at high vascular risk
    • Accessed September 25, 2015
    • Boehringer Ingelheim Pharmaceuticals. CARMELINA: Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in patients with type 2 diabetes mellitus at high vascular risk. http://clinicaltrials.gov/ct2/show/NCT01897532?term=NCT01897532&rank=1. Accessed September 25, 2015.
  • 69
    • 84928197116 scopus 로고    scopus 로고
    • Standards of medical care in diabetes: 2015
    • American Diabetes Association. Standards of medical care in diabetes: 2015. Diabetes Care. 2015;38(suppl 1):S67-S69.
    • (2015) Diabetes Care , vol.38 , pp. S67-S69
  • 70
    • 77957742069 scopus 로고    scopus 로고
    • Severe hypoglycemia and risks of vascular events and death
    • Zoungas S, Patel A, Chalmers J et al. Severe hypoglycemia and risks of vascular events and death. N Engl J Med. 2010;363(15):1410-1418.
    • (2010) N Engl J Med , vol.363 , Issue.15 , pp. 1410-1418
    • Zoungas, S.1    Patel, A.2    Chalmers, J.3
  • 71
    • 84861906592 scopus 로고    scopus 로고
    • Association between hypoglycaemic events and fall-related fractures in Medicare-covered patients with type 2 diabetes
    • Johnston SS, Conner C, Aagren M, Ruiz K, Bouchard J. Association between hypoglycaemic events and fall-related fractures in Medicare-covered patients with type 2 diabetes. Diabetes Obes Metab. 2012;14(7):634-643.
    • (2012) Diabetes Obes Metab , vol.14 , Issue.7 , pp. 634-643
    • Johnston, S.S.1    Conner, C.2    Aagren, M.3    Ruiz, K.4    Bouchard, J.5
  • 72
    • 81855169543 scopus 로고    scopus 로고
    • Emergency hospitalizations for adverse drug events in older Americans
    • Budnitz DS, Lovegrove MC, Shehab N, Richards CL. Emergency hospitalizations for adverse drug events in older Americans. N Engl J Med. 2011;365(21):2002-2012.
    • (2011) N Engl J Med , vol.365 , Issue.21 , pp. 2002-2012
    • Budnitz, D.S.1    Lovegrove, M.C.2    Shehab, N.3    Richards, C.L.4
  • 73
    • 84896717796 scopus 로고    scopus 로고
    • Direct medical costs of complications of diabetes in the United States: estimates for event-year and annual state costs (USD 2012)
    • Ward A, Alvarez P, Vo L, Martin S. Direct medical costs of complications of diabetes in the United States: estimates for event-year and annual state costs (USD 2012). J Med Econ. 2014;17(3):176-183.
    • (2014) J Med Econ , vol.17 , Issue.3 , pp. 176-183
    • Ward, A.1    Alvarez, P.2    Vo, L.3    Martin, S.4
  • 74
    • 84859857179 scopus 로고    scopus 로고
    • American Geriatrics Society updated Beers criteria for potentially inappropriate medication use in older adults: the American Geriatrics Society 2012 Beers Criteria Update Expert Panel
    • Campanelli C. American Geriatrics Society updated Beers criteria for potentially inappropriate medication use in older adults: the American Geriatrics Society 2012 Beers Criteria Update Expert Panel. J Am Geriatr Soc. 2012;60(4):616-631.
    • (2012) J Am Geriatr Soc , vol.60 , Issue.4 , pp. 616-631
    • Campanelli, C.1
  • 75
    • 84886297885 scopus 로고    scopus 로고
    • Linagliptin for patients aged 70 years or older with type 2 diabetes inadequately controlled with common antidiabetes treatments: a randomised, double-blind, placebo-controlled trial
    • Barnett AH, Huisman H, Jones R, von Eynatten M, Patel S, Woerle HJ. Linagliptin for patients aged 70 years or older with type 2 diabetes inadequately controlled with common antidiabetes treatments: a randomised, double-blind, placebo-controlled trial. Lancet. 2013;382(9902):1413-1423.
    • (2013) Lancet , vol.382 , Issue.9902 , pp. 1413-1423
    • Barnett, A.H.1    Huisman, H.2    Jones, R.3    von Eynatten, M.4    Patel, S.5    Woerle, H.J.6
  • 76
    • 84876221922 scopus 로고    scopus 로고
    • Tolerability and efficacy of glycemic control with saxagliptin in older patients (aged >/= 65 years) with inadequately controlled type 2 diabetes mellitus
    • Karyekar CS, Ravichandran S, Allen E, Fleming D, Frederich R. Tolerability and efficacy of glycemic control with saxagliptin in older patients (aged >/= 65 years) with inadequately controlled type 2 diabetes mellitus. Clin Interv Aging. 2013;8:419-430.
    • (2013) Clin Interv Aging , vol.8 , pp. 419-430
    • Karyekar, C.S.1    Ravichandran, S.2    Allen, E.3    Fleming, D.4    Frederich, R.5
  • 77
    • 84883742095 scopus 로고    scopus 로고
    • Alogliptin versus glipizide monotherapy in elderly type 2 diabetes mellitus patients with mild hyperglycaemia: a prospective, double-blind, randomized, 1-year study
    • Rosenstock J, Wilson C, Fleck P. Alogliptin versus glipizide monotherapy in elderly type 2 diabetes mellitus patients with mild hyperglycaemia: a prospective, double-blind, randomized, 1-year study. Diabetes Obes Metab. 2013;15(10):906-914.
    • (2013) Diabetes Obes Metab , vol.15 , Issue.10 , pp. 906-914
    • Rosenstock, J.1    Wilson, C.2    Fleck, P.3
  • 78
    • 79954508355 scopus 로고    scopus 로고
    • Efficacy and tolerability of sitagliptin monotherapy in elderly patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial
    • Barzilai N, Guo H, Mahoney EM et al. Efficacy and tolerability of sitagliptin monotherapy in elderly patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Curr Med Res Opin. 2011;27(5):1049-1058.
    • (2011) Curr Med Res Opin , vol.27 , Issue.5 , pp. 1049-1058
    • Barzilai, N.1    Guo, H.2    Mahoney, E.M.3
  • 79
    • 84926175717 scopus 로고    scopus 로고
    • Managing older people with type 2 diabetes
    • Accessed September 25, 2015
    • International Diabetes Federation. Managing older people with type 2 diabetes. http://www.idf.org/guidelines/managing-older-people-type-2-diabetes. Accessed September 25, 2015.
  • 80
    • 84964992629 scopus 로고    scopus 로고
    • National diabetes statistics report: estimates of diabetes and its burden in the United States
    • Accessed September 25, 2015
    • Centers for Disease Control and Prevention. National diabetes statistics report: estimates of diabetes and its burden in the United States, 2014. http://www.cdc.gov/diabetes/pubs/statsreport14/national-diabetes-report-web.pdf. Accessed September 25, 2015.
    • (2014)
  • 81
    • 80053916584 scopus 로고    scopus 로고
    • National chronic kidney disease fact sheet
    • Accessed September 25, 2015
    • Centers for Disease Control and Prevention. National chronic kidney disease fact sheet 2014. http://www.cdc.gov/diabetes/pubs/pdf/kidney_Factsheet.pdf. Accessed September 25, 2015.
    • (2014)
  • 82
    • 79951591247 scopus 로고    scopus 로고
    • Antidiabetic agents in patients with chronic kidney disease and end-stage renal disease on dialysis: metabolism and clinical practice
    • Abe M, Okada K, Soma M. Antidiabetic agents in patients with chronic kidney disease and end-stage renal disease on dialysis: metabolism and clinical practice. Curr Drug Metab. 2011;12(1):57-69.
    • (2011) Curr Drug Metab , vol.12 , Issue.1 , pp. 57-69
    • Abe, M.1    Okada, K.2    Soma, M.3
  • 83
    • 84876543147 scopus 로고    scopus 로고
    • Managing diabetic patients with moderate or severe renal impairment using DPP-4 inhibitors: focus on vildagliptin
    • Russo E, Penno G, Del Prato S. Managing diabetic patients with moderate or severe renal impairment using DPP-4 inhibitors: focus on vildagliptin. Diabetes Metab Syndr Obes. 2013;6:161-170.
    • (2013) Diabetes Metab Syndr Obes , vol.6 , pp. 161-170
    • Russo, E.1    Penno, G.2    Del Prato, S.3
  • 84
    • 84993770364 scopus 로고    scopus 로고
    • Princeton, NJ: Bristol-Myers Squibb Co
    • Glucophage® (metformin) [package insert]. Princeton, NJ: Bristol-Myers Squibb Co; 2009.
    • (2009)
  • 85
    • 79955048927 scopus 로고    scopus 로고
    • Saxagliptin improves glycaemic control and is well tolerated in patients with type 2 diabetes mellitus and renal impairment
    • Nowicki M, Rychlik I, Haller H, Warren L, Suchower L, Gause-Nilsson I. Saxagliptin improves glycaemic control and is well tolerated in patients with type 2 diabetes mellitus and renal impairment. Diabetes Obes Metab. 2011;13(6):523-532.
    • (2011) Diabetes Obes Metab , vol.13 , Issue.6 , pp. 523-532
    • Nowicki, M.1    Rychlik, I.2    Haller, H.3    Warren, L.4    Suchower, L.5    Gause-Nilsson, I.6
  • 86
    • 84876785125 scopus 로고    scopus 로고
    • Efficacy and safety of sitagliptin versus glipizide in patients with type 2 diabetes and moderate-to-severe chronic renal insufficiency
    • Arjona Ferreira JC, Marre M, Barzilai N et al. Efficacy and safety of sitagliptin versus glipizide in patients with type 2 diabetes and moderate-to-severe chronic renal insufficiency. Diabetes Care. 2013;36(5):1067-1073.
    • (2013) Diabetes Care , vol.36 , Issue.5 , pp. 1067-1073
    • Arjona Ferreira, J.C.1    Marre, M.2    Barzilai, N.3
  • 87
    • 42149172434 scopus 로고    scopus 로고
    • The metabolic effects of once daily extended-release metformin in patients with type 2 diabetes: a multicentre study
    • Gao H, Xiao W, Wang C et al. The metabolic effects of once daily extended-release metformin in patients with type 2 diabetes: a multicentre study. Int J Clin Pract. 2008;62(5):695-700.
    • (2008) Int J Clin Pract , vol.62 , Issue.5 , pp. 695-700
    • Gao, H.1    Xiao, W.2    Wang, C.3
  • 88
    • 33645819547 scopus 로고    scopus 로고
    • Efficacy, tolerability, and safety of a novel once-daily extended-release metformin in patients with type 2 diabetes
    • Schwartz S, Fonseca V, Berner B, Cramer M, Chiang YK, Lewin A. Efficacy, tolerability, and safety of a novel once-daily extended-release metformin in patients with type 2 diabetes. Diabetes Care. 2006;29(4):759-764.
    • (2006) Diabetes Care , vol.29 , Issue.4 , pp. 759-764
    • Schwartz, S.1    Fonseca, V.2    Berner, B.3    Cramer, M.4    Chiang, Y.K.5    Lewin, A.6
  • 89
    • 22244470759 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of a novel extended-release metformin formulation
    • Timmins P, Donahue S, Meeker J, Marathe P. Steady-state pharmacokinetics of a novel extended-release metformin formulation. Clin Pharmacokinet. 2005;44(7):721-729.
    • (2005) Clin Pharmacokinet , vol.44 , Issue.7 , pp. 721-729
    • Timmins, P.1    Donahue, S.2    Meeker, J.3    Marathe, P.4
  • 90
  • 91
    • 84857807784 scopus 로고    scopus 로고
    • Fixed-dose combinations for treatment of type 2 diabetes mellitus
    • Blonde L, San Juan ZT. Fixed-dose combinations for treatment of type 2 diabetes mellitus. Adv Ther. 2012;29(1):1-13.
    • (2012) Adv Ther , vol.29 , Issue.1 , pp. 1-13
    • Blonde, L.1    San Juan, Z.T.2
  • 92
    • 0036211463 scopus 로고    scopus 로고
    • Adherence to oral antidiabetic therapy in a managed care organization: a comparison of monotherapy, combination therapy, and fixed-dose combination therapy
    • Melikian C, White TJ, Vanderplas A, Dezii CM, Chang E. Adherence to oral antidiabetic therapy in a managed care organization: a comparison of monotherapy, combination therapy, and fixed-dose combination therapy. Clin Ther. 2002;24(3):460-467.
    • (2002) Clin Ther , vol.24 , Issue.3 , pp. 460-467
    • Melikian, C.1    White, T.J.2    Vanderplas, A.3    Dezii, C.M.4    Chang, E.5


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