-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal, A. et al. Global cancer statistics. CA Cancer J Clin 61, 69-90 (2011).
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
-
2
-
-
34247891719
-
A translational view of the molecular pathogenesis of lung cancer
-
Sato, M., Shames, D. S., Gazdar, A. F. & Minna, J. D. A translational view of the molecular pathogenesis of lung cancer. J Thorac Oncol 2, 327-343 (2007).
-
(2007)
J Thorac Oncol
, vol.2
, pp. 327-343
-
-
Sato, M.1
Shames, D.S.2
Gazdar, A.F.3
Minna, J.D.4
-
3
-
-
52649131951
-
Lung Cancer
-
Herbst, R. S., Heymach, J. V. & Lippman, S. M. Lung Cancer. New England Journal of Medicine 359, 1367-1380 (2008).
-
(2008)
New England Journal of Medicine
, vol.359
, pp. 1367-1380
-
-
Herbst, R.S.1
Heymach, J.V.2
Lippman, S.M.3
-
4
-
-
65349107082
-
KRAS mutations in non-small cell lung cancer
-
Riely, G. J., Marks, J. & Pao, W. KRAS mutations in non-small cell lung cancer. Proc Am Thorac Soc 6, 201-205 (2009).
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 201-205
-
-
Riely, G.J.1
Marks, J.2
Pao, W.3
-
5
-
-
54249117763
-
A SNP in a let-7 microRNA complementary site in the KRAS 3′ untranslated region increases non-small cell lung cancer risk
-
Chin, L. J. et al. A SNP in a let-7 microRNA complementary site in the KRAS 3′ untranslated region increases non-small cell lung cancer risk. Cancer Res 68, 8535-8540 (2008).
-
(2008)
Cancer Res
, vol.68
, pp. 8535-8540
-
-
Chin, L.J.1
-
6
-
-
79953165309
-
A 3′ -untranslated region KRAS variant and triple-negative breast cancer: A case-control and genetic analysis
-
Paranjape, T. et al. A 3′ -untranslated region KRAS variant and triple-negative breast cancer: a case-control and genetic analysis. Lancet Oncol 12, 377-386 (2011).
-
(2011)
Lancet Oncol
, vol.12
, pp. 377-386
-
-
Paranjape, T.1
-
7
-
-
66749164641
-
A let-7 microRNA-binding site polymorphism in the KRAS 3′ UTR is associated with reduced survival in oral cancers
-
Christensen, B. C. et al. A let-7 microRNA-binding site polymorphism in the KRAS 3′ UTR is associated with reduced survival in oral cancers. Carcinogenesis 30, 1003-1007 (2009).
-
(2009)
Carcinogenesis
, vol.30
, pp. 1003-1007
-
-
Christensen, B.C.1
-
8
-
-
84055212034
-
A Let-7 MicroRNA SNP in the KRAS 3′ UTR Is Prognostic in Early-Stage Colorectal Cancer
-
Smits, K. M. et al. A Let-7 MicroRNA SNP in the KRAS 3′ UTR Is Prognostic in Early-Stage Colorectal Cancer. Clin Cancer Res 17, 7723-7731 (2011).
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7723-7731
-
-
Smits, K.M.1
-
9
-
-
84884271307
-
KRas-LCS6 polymorphism does not impact on outcomes in ovarian cancer
-
Caiola, E. et al. KRas-LCS6 polymorphism does not impact on outcomes in ovarian cancer. Am J Cancer Res 2, 298-308 (2012).
-
(2012)
Am J Cancer Res
, vol.2
, pp. 298-308
-
-
Caiola, E.1
-
10
-
-
79957925584
-
The role of KRAS rs61764370 in invasive epithelial ovarian cancer: Implications for clinical testing
-
Pharoah, P. D. et al. The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. Clin Cancer Res 17, 3742-3750 (2011).
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3742-3750
-
-
Pharoah, P.D.1
-
11
-
-
84867867113
-
A KRAS variant is a biomarker of poor outcome, platinum chemotherapy resistance and a potential target for therapy in ovarian cancer
-
Ratner, E. S. et al. A KRAS variant is a biomarker of poor outcome, platinum chemotherapy resistance and a potential target for therapy in ovarian cancer. Oncogene 31, 4559-4566 (2011).
-
(2011)
Oncogene
, vol.31
, pp. 4559-4566
-
-
Ratner, E.S.1
-
12
-
-
77953362059
-
KRAS mutation, KRAS-LCS6 polymorphism, and non-small cell lung cancer
-
Nelson, H. H. et al. KRAS mutation, KRAS-LCS6 polymorphism, and non-small cell lung cancer. Lung Cancer 69, 51-53 (2010).
-
(2010)
Lung Cancer
, vol.69
, pp. 51-53
-
-
Nelson, H.H.1
-
13
-
-
84943765451
-
Value of KRAS as prognostic or predictive marker in NSCLC: Results from the TAILOR trial
-
Rulli, E. et al. Value of KRAS as prognostic or predictive marker in NSCLC: results from the TAILOR trial. Ann Oncol, (2015). doi: 10.1093/annonc/mdv318.
-
(2015)
Ann Oncol
-
-
Rulli, E.1
-
14
-
-
84883055532
-
Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): A randomised controlled trial
-
Garassino, M. C. et al. Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial. Lancet Oncol 14, 981-988 (2013).
-
(2013)
Lancet Oncol
, vol.14
, pp. 981-988
-
-
Garassino, M.C.1
-
15
-
-
19944430434
-
The role of RAS oncogene in survival of patients with lung cancer: A systematic review of the literature with meta-analysis
-
Mascaux, C. et al. The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis. Br J Cancer 92, 131-139 (2005).
-
(2005)
Br J Cancer
, vol.92
, pp. 131-139
-
-
Mascaux, C.1
-
16
-
-
52749099497
-
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
Linardou, H. et al. Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. The Lancet Oncology 9, 962-972 (2008).
-
(2008)
The Lancet Oncology
, vol.9
, pp. 962-972
-
-
Linardou, H.1
-
17
-
-
84926182327
-
Should KRAS mutation still be used as a routine predictor of response to EGFR-TKIs in advanced non-small-cell lung cancer? A revaluation based on meta-analysis
-
Ying, M., Zhu, X., Chen, K., Sha, Z. & Chen, L. Should KRAS mutation still be used as a routine predictor of response to EGFR-TKIs in advanced non-small-cell lung cancer? A revaluation based on meta-analysis. J Cancer Res Clin Oncol, (2015). doi: 10.1007/s00432-015-1910-9.
-
(2015)
J Cancer Res Clin Oncol
-
-
Ying, M.1
Zhu, X.2
Chen, K.3
Sha, Z.4
Chen, L.5
-
18
-
-
84903954150
-
Across the universe of k-ras mutations in non-small-cell-lung cancer
-
Piva, S. et al. Across the universe of k-ras mutations in non-small-cell-lung cancer. Curr Pharm Des 20, 3933-3943 (2014).
-
(2014)
Curr Pharm Des
, vol.20
, pp. 3933-3943
-
-
Piva, S.1
-
19
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson, S. M. et al. RAS is regulated by the let-7 microRNA family. Cell 120, 635-647 (2005).
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
-
20
-
-
34247565615
-
The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
-
Lee, Y. S. & Dutta, A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 21, 1025-1030 (2007).
-
(2007)
Genes Dev
, vol.21
, pp. 1025-1030
-
-
Lee, Y.S.1
Dutta, A.2
-
21
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
Reinhart, B. J. et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403, 901-906 (2000).
-
(2000)
Nature
, vol.403
, pp. 901-906
-
-
Reinhart, B.J.1
-
22
-
-
34548012848
-
The let-7 microRNA represses cell proliferation pathways in human cells
-
Johnson, C. D. et al. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res 67, 7713-7722 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 7713-7722
-
-
Johnson, C.D.1
-
23
-
-
41649114199
-
Suppression of non-small cell lung tumor development by the let-7 microRNA family
-
Kumar, M. S. et al. Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci USA 105, 3903-3908 (2008).
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3903-3908
-
-
Kumar, M.S.1
-
24
-
-
2542626605
-
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
-
Takamizawa, J. et al. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 64, 3753-3756 (2004).
-
(2004)
Cancer Res
, vol.64
, pp. 3753-3756
-
-
Takamizawa, J.1
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