A mouse model of Townes-Brocks syndrome expressing a truncated mutant sall1 protein is protected from acute kidney injury

American Journal of Physiology - Renal Physiology

Volumn 309, Issue 10, 2015, Pages F852-F863

  Hirsch, Sara ^a,b   El Achkar, Tarek ^c   Robbins, Lynn ^a,b   Basta, Jeannine ^a,b   Heitmeier, Monique ^a   Nishinakamura, Ryuichi ^d   Rauchman, Michael ^a,b  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA St Louis Health Care System   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Acute kidney injury; Nephrotoxicity; Renal hypoplasia; Sall1; Townes Brocks syndrome

Indexed keywords

ARISTOLOCHIC ACID; HEME OXYGENASE 1; MUTANT PROTEIN; SALL1 PROTEIN; UNCLASSIFIED DRUG; SALL1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ACUTE KIDNEY FAILURE; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; EMBRYO; FEMALE; GENE EXPRESSION; GENE FUNCTION; IN VITRO STUDY; IN VIVO STUDY; ISCHEMIC PRECONDITIONING; KIDNEY; KIDNEY EPITHELIUM; KIDNEY ISCHEMIA; KIDNEY TUBULE; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; RENAL PROTECTION; REPERFUSION INJURY; SINGLE DRUG DOSE; TOWNES BROCKS SYNDROME; ANIMAL; ANUS ATRESIA; CONGENITAL MALFORMATION; DISEASE MODEL; GENETICS; METABOLISM; MULTIPLE MALFORMATION SYNDROME; MUTATION; PERCEPTION DEAFNESS; THUMB; TRANSGENIC MOUSE;

ABNORMALITIES, MULTIPLE; ACUTE KIDNEY INJURY; ANIMALS; ANUS, IMPERFORATE; DISEASE MODELS, ANIMAL; HEARING LOSS, SENSORINEURAL; HEME OXYGENASE-1; MICE, TRANSGENIC; MUTANT PROTEINS; MUTATION; REPERFUSION INJURY; THUMB; TRANSCRIPTION FACTORS;

EID: 84947227133     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00222.2015     Document Type: Article

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