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Volumn 5, Issue 3, 2015, Pages 277-284

Ginsenoside Rg1 protects against transient focal cerebral ischemic injury and suppresses its systemic metabolic changes in cerabral injury rats

Author keywords

Biomarkers; Ginsenoside Rg1; MCAO; Metabolites

Indexed keywords

GINSENOSIDE RG 1;

EID: 84947202361     PISSN: 22113835     EISSN: 22113843     Source Type: Journal    
DOI: 10.1016/j.apsb.2015.02.001     Document Type: Article
Times cited : (42)

References (23)
  • 1
    • 19544376511 scopus 로고    scopus 로고
    • Neuroprotection for ischemic stroke: two decades of success and failure
    • Cheng Y.D., Al-Khoury L., Zivin J.A. Neuroprotection for ischemic stroke: two decades of success and failure. NeuroRx 2004, 1:36-45.
    • (2004) NeuroRx , vol.1 , pp. 36-45
    • Cheng, Y.D.1    Al-Khoury, L.2    Zivin, J.A.3
  • 2
    • 0037713477 scopus 로고    scopus 로고
    • Why have so many drugs with stellar results in laboratory stroke models failed in clinical trials? A theory based on allometric relationships
    • Curry S.H. Why have so many drugs with stellar results in laboratory stroke models failed in clinical trials? A theory based on allometric relationships. Ann NY Acad Sci 2003, 993:69-74.
    • (2003) Ann NY Acad Sci , vol.993 , pp. 69-74
    • Curry, S.H.1
  • 3
    • 0036330007 scopus 로고    scopus 로고
    • Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions
    • Gladstone D.J., Black S.E., Hakim A.M. Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions. Stroke: J Cereb Circ 2002, 33:2123-2136.
    • (2002) Stroke: J Cereb Circ , vol.33 , pp. 2123-2136
    • Gladstone, D.J.1    Black, S.E.2    Hakim, A.M.3
  • 5
    • 67649399618 scopus 로고    scopus 로고
    • Variation of BDNF mRNA on focol cerebral ischemia reperfusion injury in rats with notogisenoside Rg1
    • Kehong Y., Shuxing G., Bingying X., Junling Y., Lanou W. Variation of BDNF mRNA on focol cerebral ischemia reperfusion injury in rats with notogisenoside Rg1. J Chin Med Mater 2007, 30:313-316.
    • (2007) J Chin Med Mater , vol.30 , pp. 313-316
    • Kehong, Y.1    Shuxing, G.2    Bingying, X.3    Junling, Y.4    Lanou, W.5
  • 6
    • 11844268081 scopus 로고    scopus 로고
    • Ginsenoside Rg1 reduces MPTP-induced substantia nigra neuron loss by suppressing oxidative stress
    • Chen X.C., Zhou Y.C., Chen Y., Zhu Y.G., Fang F., Chen L.M. Ginsenoside Rg1 reduces MPTP-induced substantia nigra neuron loss by suppressing oxidative stress. Acta Pharmacol Sin 2005, 26:56-62.
    • (2005) Acta Pharmacol Sin , vol.26 , pp. 56-62
    • Chen, X.C.1    Zhou, Y.C.2    Chen, Y.3    Zhu, Y.G.4    Fang, F.5    Chen, L.M.6
  • 7
    • 72149127646 scopus 로고    scopus 로고
    • Ginsenoside Rg1 protects against 6-OHDA-induced toxicity in MES23.5 cells via AKT and ERK signaling pathways
    • Ge K.L., Chen W.F., Xie J.X., Wong M.S. Ginsenoside Rg1 protects against 6-OHDA-induced toxicity in MES23.5 cells via AKT and ERK signaling pathways. J Ethnopharmacol 2010, 127:118-123.
    • (2010) J Ethnopharmacol , vol.127 , pp. 118-123
    • Ge, K.L.1    Chen, W.F.2    Xie, J.X.3    Wong, M.S.4
  • 8
    • 77952571581 scopus 로고    scopus 로고
    • Neuroprotective effects and brain transport of ginsenoside Rg1
    • Wang R., Li Y.N., Wang G.J., Hao H.P., Wu X.L., Zhou F. Neuroprotective effects and brain transport of ginsenoside Rg1. Chin J Nat Med 2009, 7:315-320.
    • (2009) Chin J Nat Med , vol.7 , pp. 315-320
    • Wang, R.1    Li, Y.N.2    Wang, G.J.3    Hao, H.P.4    Wu, X.L.5    Zhou, F.6
  • 9
    • 77952474472 scopus 로고    scopus 로고
    • Untargeted metabolic profiling reveals potential biomarkers in myocardial infarction and its application
    • Yao H., Shi P., Zhang L., Fan X., Shao Q., Cheng Y. Untargeted metabolic profiling reveals potential biomarkers in myocardial infarction and its application. Mol Biosyst 2010, 6:1061-1070.
    • (2010) Mol Biosyst , vol.6 , pp. 1061-1070
    • Yao, H.1    Shi, P.2    Zhang, L.3    Fan, X.4    Shao, Q.5    Cheng, Y.6
  • 10
    • 41649106485 scopus 로고    scopus 로고
    • Mass spectrometry-based metabolic profiling of rat urine associated with general toxicity induced by the multiglycoside of tripterygium wilfordii hook. F
    • Chen M., Ni Y., Duan H., Qiu Y., Guo C., Jiao Y., et al. Mass spectrometry-based metabolic profiling of rat urine associated with general toxicity induced by the multiglycoside of tripterygium wilfordii hook. F. Chem Res Toxicol 2008, 21:288-294.
    • (2008) Chem Res Toxicol , vol.21 , pp. 288-294
    • Chen, M.1    Ni, Y.2    Duan, H.3    Qiu, Y.4    Guo, C.5    Jiao, Y.6
  • 11
    • 29144486833 scopus 로고    scopus 로고
    • Metabonomic study on the biochemical profiles of a hydrocortisone-induced animal model
    • Chen M., Zhao L., Jia W. Metabonomic study on the biochemical profiles of a hydrocortisone-induced animal model. J Proteome Res 2005, 4:2391-2396.
    • (2005) J Proteome Res , vol.4 , pp. 2391-2396
    • Chen, M.1    Zhao, L.2    Jia, W.3
  • 12
    • 8844226701 scopus 로고    scopus 로고
    • Discrimination of type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles
    • Yang J., Xu G., Hong Q., Liebich H.M., Lutz K., Schmulling R.M., et al. Discrimination of type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles. J Chromatogr B Anal Technol Biomed Life Sci 2004, 813:53-58.
    • (2004) J Chromatogr B Anal Technol Biomed Life Sci , vol.813 , pp. 53-58
    • Yang, J.1    Xu, G.2    Hong, Q.3    Liebich, H.M.4    Lutz, K.5    Schmulling, R.M.6
  • 13
    • 79952311366 scopus 로고    scopus 로고
    • A metabonomic approach applied to predict patients with cerebral infarction
    • Jiang Z., Sun J., Liang Q., Cai Y., Li S., Huang Y., et al. A metabonomic approach applied to predict patients with cerebral infarction. Talanta 2011, 84:298-304.
    • (2011) Talanta , vol.84 , pp. 298-304
    • Jiang, Z.1    Sun, J.2    Liang, Q.3    Cai, Y.4    Li, S.5    Huang, Y.6
  • 14
    • 66849142361 scopus 로고    scopus 로고
    • Pretreatment with electroacupuncture induces rapid tolerance to focal cerebral ischemia through regulation of endocannabinoid system
    • Wang Q., Peng Y., Chen S., Gou X., Hu B., Du J., et al. Pretreatment with electroacupuncture induces rapid tolerance to focal cerebral ischemia through regulation of endocannabinoid system. Stroke: J Cereb Circ 2009, 40:2157-2164.
    • (2009) Stroke: J Cereb Circ , vol.40 , pp. 2157-2164
    • Wang, Q.1    Peng, Y.2    Chen, S.3    Gou, X.4    Hu, B.5    Du, J.6
  • 15
    • 67649312206 scopus 로고    scopus 로고
    • A rat middle cerebral artery occlusion model and intravenous cellular delivery
    • Sasaki M., Honmou O., Kocsis J.D. A rat middle cerebral artery occlusion model and intravenous cellular delivery. Methods Mol Biol 2009, 549:187-195.
    • (2009) Methods Mol Biol , vol.549 , pp. 187-195
    • Sasaki, M.1    Honmou, O.2    Kocsis, J.D.3
  • 16
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke: J Cereb Circ 1989, 20:84-91.
    • (1989) Stroke: J Cereb Circ , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 17
    • 69149094098 scopus 로고    scopus 로고
    • International stroke society-who global stroke initiative: a report on population-based mumbai stroke registry (2005-2006), India
    • Dalal P., Bhattacharjee M., Vairale J., Bhat P. International stroke society-who global stroke initiative: a report on population-based mumbai stroke registry (2005-2006), India. Int J Stroke 2009, 4:239-240.
    • (2009) Int J Stroke , vol.4 , pp. 239-240
    • Dalal, P.1    Bhattacharjee, M.2    Vairale, J.3    Bhat, P.4
  • 19
    • 78651408055 scopus 로고    scopus 로고
    • Ginseng total saponins enhance neurogenesis after focal cerebral ischemia
    • Zheng G.Q., Cheng W., Wang Y., Wang X.M., Zhao S.Z., Zhou Y., et al. Ginseng total saponins enhance neurogenesis after focal cerebral ischemia. J Ethnopharmacol 2010, 133:724-728.
    • (2010) J Ethnopharmacol , vol.133 , pp. 724-728
    • Zheng, G.Q.1    Cheng, W.2    Wang, Y.3    Wang, X.M.4    Zhao, S.Z.5    Zhou, Y.6
  • 20
    • 79955036020 scopus 로고    scopus 로고
    • Radix/rhizoma notoginseng extract (sanchitongtshu) for ischemic stroke: a randomized controlled study
    • He L., Chen X., Zhou M., Zhang D., Yang J., Yang M., et al. Radix/rhizoma notoginseng extract (sanchitongtshu) for ischemic stroke: a randomized controlled study. Phytomedicine 2010, 18:437-442.
    • (2010) Phytomedicine , vol.18 , pp. 437-442
    • He, L.1    Chen, X.2    Zhou, M.3    Zhang, D.4    Yang, J.5    Yang, M.6
  • 21
    • 78650415275 scopus 로고    scopus 로고
    • Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-κB activation
    • Liu Q., Kou J.P., Yu B.Y. Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-κB activation. Neurochem Int 2011, 58:119-125.
    • (2011) Neurochem Int , vol.58 , pp. 119-125
    • Liu, Q.1    Kou, J.P.2    Yu, B.Y.3
  • 23
    • 79952102075 scopus 로고    scopus 로고
    • Early predictive biomarkers for lesion after transient cerebral ischemia
    • Berthet C., Lei H., Gruetter R., Hirt L. Early predictive biomarkers for lesion after transient cerebral ischemia. Stroke: J Cereb Circ 2011, 42:799-805.
    • (2011) Stroke: J Cereb Circ , vol.42 , pp. 799-805
    • Berthet, C.1    Lei, H.2    Gruetter, R.3    Hirt, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.