메뉴 건너뛰기




Volumn 17, Issue 4, 2015, Pages 364-372

Role of Oxidative Stress in the Worsening of Neurologic Wilson Disease Following Chelating Therapy

Author keywords

Copper; Glutathione; Lipid peroxidation; Oxidative stress; Total antioxidant capacity; Wilson disease

Indexed keywords

ANTIOXIDANT; CHELATING AGENT; COPPER; GLUTATHIONE; MALONALDEHYDE; PENICILLAMINE; TRIENTINE; TROLOX C; ZINC;

EID: 84947126667     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-015-8364-8     Document Type: Article
Times cited : (27)

References (45)
  • 1
    • 67649874760 scopus 로고    scopus 로고
    • Treatment of Wilson’s disease with tetrathiomolybdate: V. Control of free copper by tetrathiomolybdate and a comparison with trientine
    • COI: 1:CAS:528:DC%2BD1MXosVakt78%3D, PID: 19595438
    • Brewer, G. J., Askari, F., Dick, R. B., Sitterly, J., Fink, J. K., Carlson, M., et al. (2009). Treatment of Wilson’s disease with tetrathiomolybdate: V. Control of free copper by tetrathiomolybdate and a comparison with trientine. Translational Research,154(2), 70–77. doi:10.1016/j.trsl.2009.05.002.
    • (2009) Translational Research , vol.154 , Issue.2 , pp. 70-77
    • Brewer, G.J.1    Askari, F.2    Dick, R.B.3    Sitterly, J.4    Fink, J.K.5    Carlson, M.6
  • 2
    • 33645733769 scopus 로고    scopus 로고
    • Treatment of Wilson disease with ammonium tetrathiomolybdate: IV. Comparison of tetrathiomolybdate and trientine in a double-blind study of treatment of the neurologic presentation of Wilson disease
    • PID: 16606763
    • Brewer, G. J., Askari, F., Lorincz, M. T., Carlson, M., Schilsky, M., Kluin, K. J., et al. (2006). Treatment of Wilson disease with ammonium tetrathiomolybdate: IV. Comparison of tetrathiomolybdate and trientine in a double-blind study of treatment of the neurologic presentation of Wilson disease. Archives of Neurology,63(4), 521–527. doi:10.1001/archneur.63.4.521.
    • (2006) Archives of Neurology , vol.63 , Issue.4 , pp. 521-527
    • Brewer, G.J.1    Askari, F.2    Lorincz, M.T.3    Carlson, M.4    Schilsky, M.5    Kluin, K.J.6
  • 3
    • 0032750436 scopus 로고    scopus 로고
    • Diagnosis and treatment of Wilson’s disease
    • COI: 1:STN:280:DC%2BD38vjslSisw%3D%3D, PID: 12194382
    • Brewer, G. J., Fink, J. K., & Hedera, P. (1999). Diagnosis and treatment of Wilson’s disease. Seminars in Neurology,19(3), 261–270. doi:10.1055/s-2008-1040842.
    • (1999) Seminars in Neurology , vol.19 , Issue.3 , pp. 261-270
    • Brewer, G.J.1    Fink, J.K.2    Hedera, P.3
  • 4
    • 0037337399 scopus 로고    scopus 로고
    • Treatment of Wilson disease with ammonium tetrathiomolybdate: III. Initial therapy in a total of 55 neurologically affected patients and follow-up with zinc therapy
    • PID: 12633149
    • Brewer, G. J., Hedera, P., Kluin, K. J., Carlson, M., Askari, F., Dick, R. B., et al. (2003). Treatment of Wilson disease with ammonium tetrathiomolybdate: III. Initial therapy in a total of 55 neurologically affected patients and follow-up with zinc therapy. Archives of Neurology,60(3), 379–385.
    • (2003) Archives of Neurology , vol.60 , Issue.3 , pp. 379-385
    • Brewer, G.J.1    Hedera, P.2    Kluin, K.J.3    Carlson, M.4    Askari, F.5    Dick, R.B.6
  • 5
    • 0023178114 scopus 로고
    • Worsening of neurologic syndrome in patients with Wilson’s disease with initial penicillamine therapy
    • COI: 1:STN:280:DyaL2s3ht1KrsQ%3D%3D, PID: 3579660
    • Brewer, G. J., Terry, C. A., Aisen, A. M., & Hill, G. M. (1987). Worsening of neurologic syndrome in patients with Wilson’s disease with initial penicillamine therapy. Archives of Neurology,44(5), 490–493.
    • (1987) Archives of Neurology , vol.44 , Issue.5 , pp. 490-493
    • Brewer, G.J.1    Terry, C.A.2    Aisen, A.M.3    Hill, G.M.4
  • 7
    • 78650146642 scopus 로고    scopus 로고
    • Long-term follow-up of Wilson disease: Natural history, treatment, mutations analysis and phenotypic correlation
    • COI: 1:CAS:528:DC%2BC3MXjsFehtw%3D%3D, PID: 20958917
    • Bruha, R., Marecek, Z., Pospisilova, L., Nevsimalova, S., Vitek, L., Martasek, P., et al. (2011). Long-term follow-up of Wilson disease: Natural history, treatment, mutations analysis and phenotypic correlation. Liver International,31(1), 83–91. doi:10.1111/j.1478-3231.2010.02354.x.
    • (2011) Liver International , vol.31 , Issue.1 , pp. 83-91
    • Bruha, R.1    Marecek, Z.2    Pospisilova, L.3    Nevsimalova, S.4    Vitek, L.5    Martasek, P.6
  • 8
    • 84863328264 scopus 로고    scopus 로고
    • Decreased serum antioxidant capacity in patients with Wilson disease is associated with neurological symptoms
    • COI: 1:CAS:528:DC%2BC38Xlt1Whtrc%3D, PID: 22139496
    • Bruha, R., Vitek, L., Marecek, Z., Pospisilova, L., Nevsimalova, S., Martasek, P., et al. (2012). Decreased serum antioxidant capacity in patients with Wilson disease is associated with neurological symptoms. Journal of Inherited Metabolic Disease,35(3), 541–548. doi:10.1007/s10545-011-9422-5.
    • (2012) Journal of Inherited Metabolic Disease , vol.35 , Issue.3 , pp. 541-548
    • Bruha, R.1    Vitek, L.2    Marecek, Z.3    Pospisilova, L.4    Nevsimalova, S.5    Martasek, P.6
  • 9
    • 0027452091 scopus 로고
    • The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene
    • COI: 1:CAS:528:DyaK2cXht1Kns7Y%3D, PID: 8298639
    • Bull, P. C., Thomas, G. R., Rommens, J. M., Forbes, J. R., & Cox, D. W. (1993). The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene. Nature Genetics,5(4), 327–337. doi:10.1038/ng1293-327.
    • (1993) Nature Genetics , vol.5 , Issue.4 , pp. 327-337
    • Bull, P.C.1    Thomas, G.R.2    Rommens, J.M.3    Forbes, J.R.4    Cox, D.W.5
  • 10
    • 84861306264 scopus 로고    scopus 로고
    • Penicillamine increases free copper and enhances oxidative stress in the brain of toxic milk mice
    • COI: 1:CAS:528:DC%2BC38XnvFGlsro%3D, PID: 22629446
    • Chen, D. B., Feng, L., Lin, X. P., Zhang, W., Li, F. R., Liang, X. L., et al. (2012). Penicillamine increases free copper and enhances oxidative stress in the brain of toxic milk mice. PLoS One,7(5), e37709. doi:10.1371/journal.pone.0037709.
    • (2012) PLoS One , vol.7 , Issue.5 , pp. e37709
    • Chen, D.B.1    Feng, L.2    Lin, X.P.3    Zhang, W.4    Li, F.R.5    Liang, X.L.6
  • 11
    • 0034977186 scopus 로고    scopus 로고
    • Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism
    • COI: 1:CAS:528:DC%2BD3MXkslWnu70%3D, PID: 11413243
    • Chen, Y., Vartiainen, N. E., Ying, W., Chan, P. H., Koistinaho, J., & Swanson, R. A. (2001). Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism. Journal of Neurochemistry,77(6), 1601–1610.
    • (2001) Journal of Neurochemistry , vol.77 , Issue.6 , pp. 1601-1610
    • Chen, Y.1    Vartiainen, N.E.2    Ying, W.3    Chan, P.H.4    Koistinaho, J.5    Swanson, R.A.6
  • 12
    • 57649158930 scopus 로고    scopus 로고
    • Copper transport to the brain by the blood-brain barrier and blood-CSF barrier
    • COI: 1:CAS:528:DC%2BD1cXhsFansrvF, PID: 19014916
    • Choi, B. S., & Zheng, W. (2009). Copper transport to the brain by the blood-brain barrier and blood-CSF barrier. Brain Research,1248, 14–21. doi:10.1016/j.brainres.2008.10.056.
    • (2009) Brain Research , vol.1248 , pp. 14-21
    • Choi, B.S.1    Zheng, W.2
  • 13
    • 0027263699 scopus 로고
    • Population-based norms for the Mini-Mental State Examination by age and educational level
    • COI: 1:STN:280:DyaK3s3ktVKkug%3D%3D, PID: 8479064
    • Crum, R. M., Anthony, J. C., Bassett, S. S., & Folstein, M. F. (1993). Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA,269(18), 2386–2391.
    • (1993) JAMA , vol.269 , Issue.18 , pp. 2386-2391
    • Crum, R.M.1    Anthony, J.C.2    Bassett, S.S.3    Folstein, M.F.4
  • 14
    • 33747752509 scopus 로고    scopus 로고
    • Wilson’s disease: An update
    • PID: 16932613
    • Das, S. K., & Ray, K. (2006). Wilson’s disease: An update. Nature Clinical Practice Neurology,2(9), 482–493. doi:10.1038/ncpneuro0291.
    • (2006) Nature Clinical Practice Neurology , vol.2 , Issue.9 , pp. 482-493
    • Das, S.K.1    Ray, K.2
  • 15
    • 0029990439 scopus 로고    scopus 로고
    • Astrocytes protect neurons from hydrogen peroxide toxicity
    • COI: 1:CAS:528:DyaK28XitFKhuro%3D, PID: 8786431
    • Desagher, S., Glowinski, J., & Premont, J. (1996). Astrocytes protect neurons from hydrogen peroxide toxicity. Journal of Neuroscience,16(8), 2553–2562.
    • (1996) Journal of Neuroscience , vol.16 , Issue.8 , pp. 2553-2562
    • Desagher, S.1    Glowinski, J.2    Premont, J.3
  • 16
    • 84883495202 scopus 로고    scopus 로고
    • Copper metabolism of astrocytes
    • COI: 1:CAS:528:DC%2BC3sXmtFWktLo%3D, PID: 23503037
    • Dringen, R., Scheiber, I. F., & Mercer, J. F. (2013). Copper metabolism of astrocytes. Frontiers in Aging Neuroscience,5, 9. doi:10.3389/fnagi.2013.00009.
    • (2013) Frontiers in Aging Neuroscience , vol.5 , pp. 9
    • Dringen, R.1    Scheiber, I.F.2    Mercer, J.F.3
  • 17
    • 0037735344 scopus 로고    scopus 로고
    • Copper toxicity, oxidative stress, and antioxidant nutrients
    • COI: 1:CAS:528:DC%2BD3sXkvVCmt7c%3D, PID: 12821289
    • Gaetke, L. M., & Chow, C. K. (2003). Copper toxicity, oxidative stress, and antioxidant nutrients. Toxicology,189(1–2), 147–163.
    • (2003) Toxicology , vol.189 , Issue.1-2 , pp. 147-163
    • Gaetke, L.M.1    Chow, C.K.2
  • 18
    • 0025980294 scopus 로고
    • Comparison of functional and structural brain disturbances in Wilson’s disease
    • COI: 1:STN:280:DyaK3M7isFKjsg%3D%3D, PID: 1992374
    • Grimm, G., Prayer, L., Oder, W., Ferenci, P., Madl, C., Knoflach, P., et al. (1991). Comparison of functional and structural brain disturbances in Wilson’s disease. Neurology,41(2 (Pt 1)), 272–276.
    • (1991) Neurology , vol.41 , pp. 272-276
    • Grimm, G.1    Prayer, L.2    Oder, W.3    Ferenci, P.4    Madl, C.5    Knoflach, P.6
  • 19
    • 84893875837 scopus 로고    scopus 로고
    • Treatment with D-penicillamine or zinc sulphate affects copper metabolism and improves but not normalizes antioxidant capacity parameters in Wilson disease
    • COI: 1:CAS:528:DC%2BC3sXhvF2rsbzI, PID: 24368744
    • Gromadzka, G., Karpinska, A., Przybylkowski, A., Litwin, T., Wierzchowska-Ciok, A., Dziezyc, K., et al. (2014). Treatment with D-penicillamine or zinc sulphate affects copper metabolism and improves but not normalizes antioxidant capacity parameters in Wilson disease. BioMetals,27(1), 207–215. doi:10.1007/s10534-013-9694-3.
    • (2014) BioMetals , vol.27 , Issue.1 , pp. 207-215
    • Gromadzka, G.1    Karpinska, A.2    Przybylkowski, A.3    Litwin, T.4    Wierzchowska-Ciok, A.5    Dziezyc, K.6
  • 20
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
    • COI: 1:CAS:528:DC%2BD3MXnvVCiur4%3D, PID: 11599635
    • Halliwell, B. (2001). Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment. Drugs and Aging,18(9), 685–716.
    • (2001) Drugs and Aging , vol.18 , Issue.9 , pp. 685-716
    • Halliwell, B.1
  • 21
    • 0025697262 scopus 로고
    • Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury
    • COI: 1:CAS:528:DyaK3MXmt1Ogsr4%3D, PID: 2079232
    • Janero, D. R. (1990). Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radical Biology and Medicine,9(6), 515–540.
    • (1990) Free Radical Biology and Medicine , vol.9 , Issue.6 , pp. 515-540
    • Janero, D.R.1
  • 22
    • 66149110340 scopus 로고    scopus 로고
    • Bile salt-induced pro-oxidant liver damage promotes transplanted cell proliferation for correcting Wilson disease in the Long-Evans Cinnamon rat model
    • COI: 1:CAS:528:DC%2BD1MXlslKmu70%3D, PID: 19185006
    • Joseph, B., Kapoor, S., Schilsky, M. L., & Gupta, S. (2009). Bile salt-induced pro-oxidant liver damage promotes transplanted cell proliferation for correcting Wilson disease in the Long-Evans Cinnamon rat model. Hepatology,49(5), 1616–1624. doi:10.1002/hep.22792.
    • (2009) Hepatology , vol.49 , Issue.5 , pp. 1616-1624
    • Joseph, B.1    Kapoor, S.2    Schilsky, M.L.3    Gupta, S.4
  • 23
    • 84897411951 scopus 로고    scopus 로고
    • Worsening of Wilson disease following penicillamine therapy
    • COI: 1:CAS:528:DC%2BC2cXlslSmu70%3D, PID: 24356057
    • Kalita, J., Kumar, V., Chandra, S., Kumar, B., & Misra, U. K. (2014a). Worsening of Wilson disease following penicillamine therapy. European Neurology,71(3–4), 126–131. doi:10.1159/000355276.
    • (2014) European Neurology , vol.71 , Issue.3-4 , pp. 126-131
    • Kalita, J.1    Kumar, V.2    Chandra, S.3    Kumar, B.4    Misra, U.K.5
  • 24
    • 84908693457 scopus 로고    scopus 로고
    • A study of oxidative stress, cytokines and glutamate in Wilson disease and their asymptomatic siblings
    • COI: 1:CAS:528:DC%2BC2cXhtFans73K, PID: 25002079
    • Kalita, J., Kumar, V., Misra, U. K., Ranjan, A., Khan, H., & Konwar, R. (2014b). A study of oxidative stress, cytokines and glutamate in Wilson disease and their asymptomatic siblings. Journal of Neuroimmunology,274(1–2), 141–148. doi:10.1016/j.jneuroim.2014.06.013.
    • (2014) Journal of Neuroimmunology , vol.274 , Issue.1-2 , pp. 141-148
    • Kalita, J.1    Kumar, V.2    Misra, U.K.3    Ranjan, A.4    Khan, H.5    Konwar, R.6
  • 25
    • 77956387380 scopus 로고    scopus 로고
    • R778L, H1069Q, and I1102T mutation study in neurologic Wilson disease
    • PID: 20739809
    • Kalita, J., Somarajan, B. I., Misra, U. K., & Mittal, B. (2010). R778L, H1069Q, and I1102T mutation study in neurologic Wilson disease. Neurology India,58(4), 627–630. doi:10.4103/0028-3886.68678.
    • (2010) Neurology India , vol.58 , Issue.4 , pp. 627-630
    • Kalita, J.1    Somarajan, B.I.2    Misra, U.K.3    Mittal, B.4
  • 26
    • 0035008460 scopus 로고    scopus 로고
    • Method for the measurement of antioxidant activity in human fluids
    • COI: 1:STN:280:DC%2BD3M3mt12juw%3D%3D, PID: 11328833
    • Koracevic, D., Koracevic, G., Djordjevic, V., Andrejevic, S., & Cosic, V. (2001). Method for the measurement of antioxidant activity in human fluids. Journal of Clinical Pathology,54(5), 356–361.
    • (2001) Journal of Clinical Pathology , vol.54 , Issue.5 , pp. 356-361
    • Koracevic, D.1    Koracevic, G.2    Djordjevic, V.3    Andrejevic, S.4    Cosic, V.5
  • 27
    • 34249001939 scopus 로고    scopus 로고
    • Reliability of the Burke–Fahn–Marsden scale in a multicenter trial for dystonia
    • PID: 17274034
    • Krystkowiak, P., du Montcel, S. T., Vercueil, L., Houeto, J. L., Lagrange, C., Cornu, P., et al. (2007). Reliability of the Burke–Fahn–Marsden scale in a multicenter trial for dystonia. Movement Disorders,22(5), 685–689. doi:10.1002/mds.21392.
    • (2007) Movement Disorders , vol.22 , Issue.5 , pp. 685-689
    • Krystkowiak, P.1    du Montcel, S.T.2    Vercueil, L.3    Houeto, J.L.4    Lagrange, C.5    Cornu, P.6
  • 28
    • 0027976087 scopus 로고
    • Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: Evidence that astrocytes play an important role in antioxidative processes in the brain
    • COI: 1:CAS:528:DyaK2cXntlygtw%3D%3D, PID: 7903354
    • Makar, T. K., Nedergaard, M., Preuss, A., Gelbard, A. S., Perumal, A. S., & Cooper, A. J. (1994). Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: Evidence that astrocytes play an important role in antioxidative processes in the brain. Journal of Neurochemistry,62(1), 45–53.
    • (1994) Journal of Neurochemistry , vol.62 , Issue.1 , pp. 45-53
    • Makar, T.K.1    Nedergaard, M.2    Preuss, A.3    Gelbard, A.S.4    Perumal, A.S.5    Cooper, A.J.6
  • 29
    • 0034811590 scopus 로고    scopus 로고
    • Protective effects of aspirin and vitamin E (alpha-tocopherol) against copper- and cadmium-induced toxicity
    • COI: 1:CAS:528:DC%2BD3MXltlWlsr8%3D
    • Mattie, M. D., & Freedman, J. H. (2001). Protective effects of aspirin and vitamin E (alpha-tocopherol) against copper- and cadmium-induced toxicity. Biochemical and Biophysics Research Communications,285(4), 921–925. doi:10.1006/bbrc.2001.5259.
    • (2001) Biochemical and Biophysics Research Communications , vol.285 , Issue.4 , pp. 921-925
    • Mattie, M.D.1    Freedman, J.H.2
  • 30
    • 33748893007 scopus 로고    scopus 로고
    • Relationship between oxidative stress and antioxidant systems in the liver of patients with Wilson disease: Hepatic manifestation in Wilson disease as a consequence of augmented oxidative stress
    • COI: 1:CAS:528:DC%2BD28XpvVOhs7g%3D, PID: 16940238
    • Nagasaka, H., Inoue, I., Inui, A., Komatsu, H., Sogo, T., Murayama, K., et al. (2006). Relationship between oxidative stress and antioxidant systems in the liver of patients with Wilson disease: Hepatic manifestation in Wilson disease as a consequence of augmented oxidative stress. Pediatric Research,60(4), 472–477. doi:10.1203/01.pdr.0000238341.12229.d3.
    • (2006) Pediatric Research , vol.60 , Issue.4 , pp. 472-477
    • Nagasaka, H.1    Inoue, I.2    Inui, A.3    Komatsu, H.4    Sogo, T.5    Murayama, K.6
  • 31
    • 64749089732 scopus 로고    scopus 로고
    • Copper intoxication; antioxidant defenses and oxidative damage in rat brain
    • COI: 1:CAS:528:DC%2BD1cXhsFartr%2FK, PID: 18784908
    • Ozcelik, D., & Uzun, H. (2009). Copper intoxication; antioxidant defenses and oxidative damage in rat brain. Biological Trace Element Research,127(1), 45–52. doi:10.1007/s12011-008-8219-3.
    • (2009) Biological Trace Element Research , vol.127 , Issue.1 , pp. 45-52
    • Ozcelik, D.1    Uzun, H.2
  • 32
    • 84930958519 scopus 로고    scopus 로고
    • MRI and oxidative stress markers in neurological worsening of Wilson disease following penicillamine
    • COI: 1:CAS:528:DC%2BC2MXpt1Kqsrk%3D, PID: 26004675
    • Ranjan, A., Kalita, J., Kumar, V., & Misra, U. K. (2015). MRI and oxidative stress markers in neurological worsening of Wilson disease following penicillamine. Neurotoxicology,49, 45–49. doi:10.1016/j.neuro.2015.05.004.
    • (2015) Neurotoxicology , vol.49 , pp. 45-49
    • Ranjan, A.1    Kalita, J.2    Kumar, V.3    Misra, U.K.4
  • 33
    • 48749098849 scopus 로고    scopus 로고
    • The mitochondrial permeability transition, and oxidative and nitrosative stress in the mechanism of copper toxicity in cultured neurons and astrocytes
    • COI: 1:CAS:528:DC%2BD1cXovV2lt7o%3D, PID: 18591939
    • Reddy, P. V., Rao, K. V., & Norenberg, M. D. (2008). The mitochondrial permeability transition, and oxidative and nitrosative stress in the mechanism of copper toxicity in cultured neurons and astrocytes. Laboratory Investigation,88(8), 816–830. doi:10.1038/labinvest.2008.49.
    • (2008) Laboratory Investigation , vol.88 , Issue.8 , pp. 816-830
    • Reddy, P.V.1    Rao, K.V.2    Norenberg, M.D.3
  • 34
    • 80052261937 scopus 로고    scopus 로고
    • Lipid peroxidation and neurodegenerative disease
    • COI: 1:CAS:528:DC%2BC3MXhtFSjsLbJ, PID: 21782935
    • Reed, T. T. (2011). Lipid peroxidation and neurodegenerative disease. Free Radical Biology and Medicine,51(7), 1302–1319. doi:10.1016/j.freeradbiomed.2011.06.027.
    • (2011) Free Radical Biology and Medicine , vol.51 , Issue.7 , pp. 1302-1319
    • Reed, T.T.1
  • 35
    • 46249112793 scopus 로고    scopus 로고
    • Diagnosis and treatment of Wilson disease: An update
    • COI: 1:CAS:528:DC%2BD1cXotVagtL4%3D, PID: 18506894
    • Roberts, E. A., Schilsky, M. L., & American Association for Study of Liver, D. (2008). Diagnosis and treatment of Wilson disease: An update. Hepatology,47(6), 2089–2111. doi:10.1002/hep.22261.
    • (2008) Hepatology , vol.47 , Issue.6 , pp. 2089-2111
    • Roberts, E.A.1    Schilsky, M.L.2    American Association for Study of Liver,, D.3
  • 36
    • 25144495638 scopus 로고    scopus 로고
    • Oxidative stress and pro-apoptotic conditions in a rodent model of Wilson’s disease
    • COI: 1:CAS:528:DC%2BD2MXhtVegurjK, PID: 16081251
    • Samuele, A., Mangiagalli, A., Armentero, M. T., Fancellu, R., Bazzini, E., Vairetti, M., et al. (2005). Oxidative stress and pro-apoptotic conditions in a rodent model of Wilson’s disease. Biochimica et Biophysica Acta,1741(3), 325–330. doi:10.1016/j.bbadis.2005.06.004.
    • (2005) Biochimica et Biophysica Acta , vol.1741 , Issue.3 , pp. 325-330
    • Samuele, A.1    Mangiagalli, A.2    Armentero, M.T.3    Fancellu, R.4    Bazzini, E.5    Vairetti, M.6
  • 37
    • 84875740221 scopus 로고    scopus 로고
    • Astrocyte functions in the copper homeostasis of the brain
    • COI: 1:CAS:528:DC%2BC38XhsVyht7jF, PID: 22982300
    • Scheiber, I. F., & Dringen, R. (2013). Astrocyte functions in the copper homeostasis of the brain. Neurochemistry International,62(5), 556–565. doi:10.1016/j.neuint.2012.08.017.
    • (2013) Neurochemistry International , vol.62 , Issue.5 , pp. 556-565
    • Scheiber, I.F.1    Dringen, R.2
  • 38
    • 0016331976 scopus 로고
    • Measurement of ceruloplasmin from its oxidase activity in serum by use of o-dianisidine dihydrochloride
    • COI: 1:CAS:528:DyaE2MXmvFGktQ%3D%3D, PID: 4214636
    • Schosinsky, K. H., Lehmann, H. P., & Beeler, M. F. (1974). Measurement of ceruloplasmin from its oxidase activity in serum by use of o-dianisidine dihydrochloride. Clinical Chemistry,20(12), 1556–1563.
    • (1974) Clinical Chemistry , vol.20 , Issue.12 , pp. 1556-1563
    • Schosinsky, K.H.1    Lehmann, H.P.2    Beeler, M.F.3
  • 39
    • 0027943858 scopus 로고
    • Oxidant injury to hepatic mitochondria in patients with Wilson’s disease and Bedlington terriers with copper toxicosis
    • COI: 1:STN:280:DyaK2M%2FkslWmuw%3D%3D, PID: 7958693
    • Sokol, R. J., Twedt, D., McKim, J. M, Jr, Devereaux, M. W., Karrer, F. M., Kam, I., et al. (1994). Oxidant injury to hepatic mitochondria in patients with Wilson’s disease and Bedlington terriers with copper toxicosis. Gastroenterology,107(6), 1788–1798.
    • (1994) Gastroenterology , vol.107 , Issue.6 , pp. 1788-1798
    • Sokol, R.J.1    Twedt, D.2    McKim, J.M.3    Devereaux, M.W.4    Karrer, F.M.5    Kam, I.6
  • 40
    • 0027978892 scopus 로고
    • Role of cytosolic copper, metallothionein and glutathione in copper toxicity in rat hepatoma tissue culture cells
    • COI: 1:CAS:528:DyaK2cXmsVygsr8%3D, PID: 7940570
    • Steinebach, O. M., & Wolterbeek, H. T. (1994). Role of cytosolic copper, metallothionein and glutathione in copper toxicity in rat hepatoma tissue culture cells. Toxicology,92(1–3), 75–90.
    • (1994) Toxicology , vol.92 , Issue.1-3 , pp. 75-90
    • Steinebach, O.M.1    Wolterbeek, H.T.2
  • 41
    • 0034105324 scopus 로고    scopus 로고
    • CSF copper concentrations, blood–brain barrier function, and coeruloplasmin synthesis during the treatment of Wilson’s disease
    • COI: 1:CAS:528:DC%2BD3cXjsFCktbc%3D, PID: 10821440
    • Stuerenburg, H. J. (2000). CSF copper concentrations, blood–brain barrier function, and coeruloplasmin synthesis during the treatment of Wilson’s disease. J Neural Transm,107(3), 321–329.
    • (2000) J Neural Transm , vol.107 , Issue.3 , pp. 321-329
    • Stuerenburg, H.J.1
  • 42
    • 0021865460 scopus 로고
    • Low content of hepatic reduced glutathione in patients with Wilson’s disease
    • COI: 1:CAS:528:DyaL2MXlt1Wit7c%3D, PID: 4052057
    • Summer, K. H., & Eisenburg, J. (1985). Low content of hepatic reduced glutathione in patients with Wilson’s disease. Biochemical Medicine,34(1), 107–111.
    • (1985) Biochemical Medicine , vol.34 , Issue.1 , pp. 107-111
    • Summer, K.H.1    Eisenburg, J.2
  • 43
    • 0028869945 scopus 로고
    • The Wilson disease gene: Spectrum of mutations and their consequences
    • COI: 1:CAS:528:DyaK2MXjsFOmsbk%3D, PID: 7626145
    • Thomas, G. R., Forbes, J. R., Roberts, E. A., Walshe, J. M., & Cox, D. W. (1995). The Wilson disease gene: Spectrum of mutations and their consequences. Nature Genetics,9(2), 210–217. doi:10.1038/ng0295-210.
    • (1995) Nature Genetics , vol.9 , Issue.2 , pp. 210-217
    • Thomas, G.R.1    Forbes, J.R.2    Roberts, E.A.3    Walshe, J.M.4    Cox, D.W.5
  • 44
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • COI: 1:CAS:528:DyaF1MXktVSlt7k%3D, PID: 4388022
    • Tietze, F. (1969). Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues. Analytical Biochemistry,27(3), 502–522.
    • (1969) Analytical Biochemistry , vol.27 , Issue.3 , pp. 502-522
    • Tietze, F.1
  • 45
    • 84922933826 scopus 로고    scopus 로고
    • Effects of tetrathiomolybdate and penicillamine on brain hydroxyl radical and free copper levels: A microdialysis study in vivo
    • COI: 1:CAS:528:DC%2BC2MXhvVOrsrw%3D
    • Zhang, J. W., Liu, J. X., Hou, H. M., Chen, D. B., Feng, L., Wu, C., et al. (2015). Effects of tetrathiomolybdate and penicillamine on brain hydroxyl radical and free copper levels: A microdialysis study in vivo. Biochemical and Biophysics Research Communications,458(1), 82–85. doi:10.1016/j.bbrc.2015.01.071.
    • (2015) Biochemical and Biophysics Research Communications , vol.458 , Issue.1 , pp. 82-85
    • Zhang, J.W.1    Liu, J.X.2    Hou, H.M.3    Chen, D.B.4    Feng, L.5    Wu, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.