The changing epidemiology of Acinetobacter spp. producing OXA carbapenemases causing bloodstream infections in Brazil: A BrasNet report

Diagnostic Microbiology and Infectious Disease

Volumn 83, Issue 4, 2015, Pages 382-385

  Vasconcelos, Ana Tereza R ^a   Barth, Afonso L ^b   Zavascki, Alexandre P ^b   Gales, Ana C ^c   Levin, Anna S ^d   Lucarevschi, Bianca R ^e   Cabral, Blenda G ^f   Brasiliense, Danielle M ^f   Rossi, Flavia ^d   Furtado, Guilherme H C ^c   Carneiro, Irna Carla R S ^f   da Silva, Juliana O ^c   Ribeiro, Julival ^g   Lima, Karla V B ^f   Correa, Luci ^c,h   Britto, Maria H ⁱ   Silva, Mariama T ^d   da Conceição, Marília L ^f   Moreira, Marina ^e   Martino, Marinês D V ^h   de Freitas, Marise R ⁱ   Oliveira, Maura S ^d   Dalben, Mirian F ^d   Guzman, Ricardo D ^g   Cayô, Rodrigo ^c   Morais, Rosângela ⁱ   Santos, Sânia A ^d   Martins, Willames M B S ^c   more..

^a LABORATÓRIO NACIONAL DE COMPUTAÇÃO CIENTÍFICA   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e UNIVERSITY OF TAUBATÉ   (Brazil)

^f INSTITUTO EVANDRO CHAGAS   (Brazil)

^g HOSPITAL DE BASE   (Brazil)

^h FACULDADE DE CIÊNCIAS MÉDICAS DA SANTA CASA DE SÃO PAULO   (Brazil)

ⁱ FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

Acinetobacter spp; Bloodstream infections; Molecular epidemiology; OXA carbapenemase

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CARBAPENEM; CARBAPENEMASE; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; DORIPENEM; DOXYCYCLINE; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; MINOCYCLINE; OXA 23 PROTEIN; OXA 72 PROTEIN; OXA PROTEIN; PIPERACILLIN PLUS TAZOBACTAM; POLYMYXIN DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SULTAMICILLIN; TETRACYCLINE DERIVATIVE; TIGECYCLINE; TIMENTIN; TOBRAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAMASE;

ACINETOBACTER; ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTION; ACINETOBACTER PITTII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; BACTERIUM ISOLATION; BLOODSTREAM INFECTION; BRAZIL; GEOGRAPHIC DISTRIBUTION; HOSPITAL INFECTION; HUMAN; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; TERTIARY CARE CENTER; ACINETOBACTER INFECTIONS; ADOLESCENT; ADULT; AGED; BACTEREMIA; CHILD; CLASSIFICATION; CLUSTER ANALYSIS; ENZYMOLOGY; FEMALE; GENETICS; GENOTYPE; INFANT; ISOLATION AND PURIFICATION; MALE; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MIDDLE AGED; MOLECULAR TYPING; MULTIDRUG RESISTANCE; NEWBORN; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; SECRETION (PROCESS); VERY ELDERLY; YOUNG ADULT;

ACINETOBACTER; ACINETOBACTER INFECTIONS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTEREMIA; BACTERIAL PROTEINS; BETA-LACTAMASES; BRAZIL; CHILD; CHILD, PRESCHOOL; CLUSTER ANALYSIS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MOLECULAR TYPING; POLYMERASE CHAIN REACTION; TERTIARY CARE CENTERS; YOUNG ADULT;

EID: 84947047144     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2015.08.006     Document Type: Article

References (22)

1. OXA-143 gene in Brazilian hospitals. Antimicrob Agents Chemother 2011, 55:1322-1323.
2. Brazilian Health Surveillance Agency (ANVISA) Boletim Informativo: Segurança e qualidade em serviço de saúde n° 9: Relatório da resistência microbiana em infecções primárias de corrente sanguínea confirmadas laboratorialmente relacionadas ao uso de cateter venoso central em unidades de terapia intensiva Accessed on 20 February 2015. Available at:. http://portal.anvisa.gov.br/wps/content/Anvisa+Portal/Anvisa/Inicio/Servicos+de+Saude/Assunto+de+Interesse/Boletim+Seguranca+do+Paciente/Seguranca+e+qualidade+em+servico+de+saude+n+9.
3. Chagas T.P., Carvalho K.R., de Oliveira Santos I.C., Carvalho-Assef A.P., Asensi M.D. Characterization of carbapenem-resistant Acinetobacter baumannii in Brazil (2008-2011): countrywide spread of OXA-23-producing clones (CC15 and CC79). Diagn Microbiol Infect Dis 2014, 79:468-472.
4. Clinical Laboratory Standard Institute (CLSI) Performance standards for antimicrobial susceptibility testing-twenty-four edition. Informational Supplement M100-S24 2014, CLSI, Wayne, PA, USA.
5. de Sá Cavalcanti F.L., Almeida A.C., Vilela M.A., de Morais Junior M.A., de Morais M.M., Leal-Balbino T.C. Emergence of extensively drug-resistant OXA-72-producing Acinetobacter baumannii in Recife, Brazil: risk of clonal dissemination?. Diagn Microbiol Infect Dis 2013, 77:250-251.
6. Diancourt L., Passet V., Nemec A., Dijkshoorn L., Brisse S. The population structure of Acinetobacter baumannii: expanding multiresistant clones from an ancestral susceptible genetic pool. PLoS One 2010, 5:e10034.
7. Espinal P., Seifert H., Dijkshoorn L., Vila J., Roca I. Rapid and accurate identification of genomic species from the Acinetobacter baumannii (Ab) group by MALDI-TOF MS. Clin Microbiol Infect 2012, 18:1097-1103.
8. European Committee on Antimicrobial Susceptibility Testing (EUCAST) Breakpoint tables for interpretation of MICs and zone diameters. Version 5.0 http://www.eucast.org.
9. Fisman D., Patrozou E., Carmeli Y., Perencevich E., Tuite A.R., Mermel L.A., et al. Geographical variability in the likelihood of bloodstream infections due to gram-negative bacteria: correlation with proximity to the equator and health care expenditure. PLoS One 2014, 9:e114548.
10. Fortaleza C.M., Caldeira S.M., Moreira R.G., Akazawa R.T., Corrente J.E., de Souza L.R., et al. Tropical healthcare epidemiology: weather determinants of the etiology of bloodstream infections in a Brazilian hospital. Infect Control Hosp Epidemiol 2014, 35:85-88.
11. Gales A.C., Castanheira M., Jones R.N., Sader H.S. Antimicrobial resistance among Gram-negative bacilli isolated from Latin America: results from SENTRY Antimicrobial Surveillance Program (Latin America, 2008-2010). Diagn Microbiol Infect Dis 2012, 73:354-360.
12. OXA-143, in Acinetobacter baumannii from Brazil: a case report. J Antimicrob Chemother 2012, 67:2531-2532.
13. Grosso F., Carvalho K.R., Quinteira S., Ramos A., Carvalho-Assef A.P., Asensi M.D., et al. OXA-23-producing Acinetobacter baumannii: a new hotspot of diversity in Rio de Janeiro?. J Antimicrob Chemother 2011, 66:62-65.
14. Higgins P.G., Dammhayn C., Hackel M., Seifert H. Global spread of carbapenem-resistant Acinetobacter baumannii. J Antimicrob Chemother 2010, 65:233-238.
15. Higgins P.G., Lehmann M., Seifert H. Inclusion of OXA-143 primers in a multiplex polymerase chain reaction (PCR) for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents 2010, 35:305.
16. La Scola B., Gundi V.A., Khamis A., Raoult D. Sequencing of the rpoB gene and flanking spacers for molecular identification of Acinetobacter species. J Clin Microbiol 2006, 44:827-832.
17. Mostachio A.K., Levin A.S., Rizek C., Rossi F., Zerbini J., Costa S.F. High prevalence of OXA-143 and alteration of outer membrane proteins in carbapenem-resistant Acinetobacter spp. isolates in Brazil. Int J Antimicrob Agents 2012, 39:396-401.
18. Schleicher X., Higgins P.G., Wisplinghoff H., Körber-Irrgang B., Kresken M., Seifert H. Molecular epidemiology of Acinetobacter baumannii and Acinetobacter nosocomialis in Germany over a 5-year period (2005-2009). Clin Microbiol Infect 2013, 19:737-742.
19. Stietz M.S., Ramírez M.S., Vilacoba E., Merkier A.K., Limansky A.S., Centrón D., et al. Acinetobacter baumannii extensively drug resistant lineages in Buenos Aires hospitals differ from the international clones I-III. Infect Genet Evol 2013, 14:294-301.
20. Towner K.J. Acinetobacter: an old friend, but a new enemy. J Hosp Infect 2009, 73:355-363.
21. Werneck J.S., Picão R.C., Carvalhaes C.G., Cardoso J.P., Gales A.C. OXA-72-producing Acinetobacter baumannii in Brazil: a case report. J Antimicrob Chemother 2011, 66:452-454.
22. OXA-143 in private hospitals in Brazil. Antimicrob Agents Chemother 2011, 55:4494-4495.