Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways

Amino Acids

Volumn 47, Issue 12, 2015, Pages 2475-2482

  Yuan, Zhao Shun ^a   Zhou, Yang Zhao ^a   Liao, Xiao Bo ^a   Luo, Jia Wen ^a   Shen, Kang Jun ^a   Hu, Ye Rong ^a   Gu, Lu ^a   Li, Jian Ming ^a   Tan, Chang Ming ^a   Chen, He Ming ^a   Zhou, Xin Min ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Alkaline phosphatase; Aortic valve calcification; APJ; Mineralization; Runt related transcription factor 2

Indexed keywords

ALKALINE PHOSPHATASE; APELIN; APELIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR RUNX2; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; APLN PROTEIN, HUMAN; CHROMONE DERIVATIVE; FLAVONOID; MORPHOLINE DERIVATIVE; RUNX2 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ADULT; ARTICLE; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART PROTECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; AORTA VALVE; AORTA VALVE STENOSIS; CALCINOSIS; CELL CULTURE; CHEMISTRY; CYTOLOGY; METABOLISM; OSTEOBLAST; PATHOLOGY; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE;

ADULT; ALKALINE PHOSPHATASE; AORTIC VALVE; AORTIC VALVE STENOSIS; CALCINOSIS; CELL DIFFERENTIATION; CELLS, CULTURED; CHROMONES; CORE BINDING FACTOR ALPHA 1 SUBUNIT; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MORPHOLINES; MUSCLE, SMOOTH, VASCULAR; OSTEOBLASTS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84947038049     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-015-2020-3     Document Type: Article

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