A GC/MS-based metabolomic approach for reliable diagnosis of phenylketonuria

Analytical and Bioanalytical Chemistry

Volumn 407, Issue 29, 2015, Pages 8825-8833

  Xiong, Xiyue ^a   Sheng, Xiaoqi ^a   Liu, Dan ^a   Zeng, Ting ^a   Peng, Ying ^a   Wang, Yichao ^a  

^a Maternal and Child Health Care Hospital of Hunan Province   (China)

Author keywords

Diagnosis; Gas chromatography mass spectrometry; Phenylacetic acid; Phenylketonuria; Phenylpyruvic acid; Urinary metabolites

Indexed keywords

AMINO ACIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; FATTY ACIDS; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PRINCIPAL COMPONENT ANALYSIS;

GAS CHROMATOGRAPHY/MASS SPECTROMETRY; PHENYLACETIC ACID; PHENYLKETONURIA; PHENYLPYRUVIC ACIDS; URINARY METABOLITES;

DIAGNOSIS;

AUTOMATED PATTERN RECOGNITION; EVALUATION STUDY; HUMAN; INFANT; MASS FRAGMENTOGRAPHY; METABOLISM; METABOLOMICS; NEWBORN; PHENYLKETONURIAS; PRINCIPAL COMPONENT ANALYSIS; PROCEDURES; SENSITIVITY AND SPECIFICITY; URINE;

GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INFANT; INFANT, NEWBORN; METABOLOMICS; PATTERN RECOGNITION, AUTOMATED; PHENYLKETONURIAS; PRINCIPAL COMPONENT ANALYSIS; SENSITIVITY AND SPECIFICITY;

EID: 84947036904     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-015-9041-3     Document Type: Article

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