Simultaneous clinical monitoring of lactic acid, pyruvic acid and ketone bodies in plasma as methoxime/tertbutyldimethylsilyl derivatives by gas chromatography-mass spectrometry in selected ion monitoring mode

Biomedical Chromatography

Volumn 22, Issue 5, 2008, Pages 450-453

  Paik, Man Jeong ^a   Cho, Eun Young ^a,b   Kim, Hoon ^c   Kim, Kyoung Rae ^c   Choi, Sangdun ^b   Ahn, Young Hwan ^a,b   Lee, Gwang ^a,b  

^a Ajou University   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c Sungkyunkwan University   (South Korea)

Author keywords

Gas chromatography mass spectrometry in selected ion monitoring mode; Ketone body; Lactic acidosis; Methoximation; Plasma; Tert butyldimethylsilylation

Indexed keywords

FATTY ACIDS; GAS CHROMATOGRAPHY; IONS; KETONES; MASS SPECTROMETRY;

3-HYDROXYBUTYRIC ACID; CLINICAL MONITORING; GAS CHROMATOGRAPHY-MASS SPECTROMETRY IN SELECTED ION MONITORING MODE; KETONE BODIES; LACTIC ACIDOSIS; METHOXIMATION; PYRUVIC ACID; SIMULTANEOUS DETERMINATIONS; TERT-BUTYLDIMETHYLSILYL DERIVATIVES; TERT-BUTYLDIMETHYLSILYLATION;

LACTIC ACID;

3 HYDROXYBUTYRIC ACID; ACETOACETIC ACID; CARBOXYLIC ACID DERIVATIVE; DIAGNOSTIC AGENT; FATTY ACID DERIVATIVE; KETONE BODY; LACTIC ACID; METHOXIME DERIVATIVE; PYRUVIC ACID; TERT BUTYLDIMETHYLSILYL DERIVATIVE;

ADULT; ANALYTICAL ERROR; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; GAS CHROMATOGRAPHY; HUMAN; ION MONITORING; KETOACIDOSIS; LACTIC ACIDOSIS; MALE; MASS SPECTROMETRY; METABOLITE; REPRODUCIBILITY; SENSITIVITY ANALYSIS;

EID: 44249098764     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.966     Document Type: Article

References (7)