Fractional flow reserve versus angiography for guidance of PCI in patients with multivessel coronary artery disease (FAME): 5-year follow-up of a randomised controlled trial

The Lancet

Volumn 386, Issue 10006, 2015, Pages 1853-1860

  Van Nunen, Lokien X ^a,b   Zimmermann, Frederik M ^a,b   Tonino, Pim A L ^a,b   Barbato, Emanuele ^c,d   Baumbach, Andreas ^b,e   Engstrøm, Thomas ^f   Klauss, Volker ^g   Maccarthy, Philip A ^h   Manoharan, Ganesh ^g,i   Oldroyd, Keith G ^j   Ver Lee, Peter N ^k   Van'T Veer, Marcel ^a,b   Fearon, William F ^l   De Bruyne, Bernard ^c   Pijls, Nico H J ^a,b  

^a CATHARINA HOSPITAL   (Netherlands)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c CARDIOVASCULAR CENTER   (Belgium)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e UNIVERSITY HOSPITALS BRISTOL NHS FOUNDATION TRUST   (United Kingdom)

^f UNIVERSITY OF COPENHAGEN   (Denmark)

^g LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^h KING S COLLEGE HOSPITAL   (United Kingdom)

ⁱ ROYAL VICTORIA HOSPITAL   (United Kingdom)

^j GOLDEN JUBILEE NATIONAL HOSPITAL   (United Kingdom)

^k EASTERN MAINE MEDICAL CENTER   (United States)

^l STANFORD UNIVERSITY MEDICAL CENTER   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRIC ACID DERIVATIVE;

ADULT; ANGIOGRAPHY; ANGIOGRAPHY FOR MULTIVESSEL EVALUATION; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DRUG ELUTING CARDIOVASCULAR STENT; EVENT FREE SURVIVAL; FEMALE; FOLLOW UP; FRACTIONAL FLOW RESERVE; HEART DISEASE; HEART EJECTION FRACTION; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; INTENTION TO TREAT ANALYSIS; INTERMETHOD COMPARISON; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTICENTER STUDY; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STABLE ANGINA PECTORIS; UNSTABLE ANGINA PECTORIS; ANGIOCARDIOGRAPHY; CLINICAL TRIAL; COMPARATIVE STUDY; MORTALITY; PROCEDURES; RADIOGRAPHY; SEX DIFFERENCE;

CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; FEMALE; FRACTIONAL FLOW RESERVE, MYOCARDIAL; HUMANS; MALE; MIDDLE AGED; PERCUTANEOUS CORONARY INTERVENTION; SEX FACTORS;

EID: 84947034333     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(15)00057-4     Document Type: Article

References (22)

1. R Hachamovitch, DS Berman, LJ Shaw et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction Circulation 97 1998 535 543
2. LJ Shaw, AE Iskandrian Prognostic value of gated myocardial perfusion SPECT J Nucl Cardiol 11 2004 171 185
3. GB Mancini, PM Hartigan, LJ Shaw et al. Predicting outcome in the COURAGE trial (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation): coronary anatomy versus ischemia JACC Cardiovasc Interv 7 2014 195 201
4. LJ Shaw, DS Berman, DJ Maron et al. Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy Circulation 117 2008 1283 1291
5. B De Bruyne, NH Pijls, B Kalesan et al. Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease N Engl J Med 367 2012 991 1001
6. B De Bruyne, WF Fearon, NH Pijls et al. Fractional flow reserve-guided PCI for stable coronary artery disease N Engl J Med 371 2014 1208 1217
7. SD Fihn, JM Gardin, J Abrams et al. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons Circulation 126 2012 e354 e471
8. S Windecker, P Kolh, F Alfonso et al. 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) Eur Heart J 35 2014 2541 2619
9. PA Tonino, B De Bruyne, NH Pijls et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention N Engl J Med 360 2009 213 224
10. NH Pijls, WF Fearon, PA Tonino et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention in patients with multivessel coronary artery disease: 2-year follow-up of the FAME (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) study J Am Coll Cardiol 56 2010 177 184
11. WF Fearon, B Bornschein, PA Tonino et al. Economic evaluation of fractional flow reserve-guided percutaneous coronary intervention in patients with multivessel disease Circulation 122 2010 2545 2550
12. WF Fearon, PA Tonino, B De Bruyne et al. Rationale and design of the Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME) study Am Heart J 154 2007 632 636
13. PW Serruys, MC Morice, AP Kappetein et al. Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease N Engl J Med 360 2009 961 972
14. R Hachamovitch, SW Hayes, JD Friedman et al. Comparison of the short-term survival benefit associated with revascularization compared with medical therapy in patients with no prior coronary artery disease undergoing stress myocardial perfusion single photon emission computed tomography Circulation 107 2003 2900 2907
15. R Hachamovitch, A Rozanski, LJ Shaw et al. Impact of ischaemia and scar on the therapeutic benefit derived from myocardial revascularization vs. medical therapy among patients undergoing stress-rest myocardial perfusion scintigraphy Eur Heart J 32 2011 1012 1024
16. M Ragosta, AH Bishop, LC Lipson et al. Comparison between angiography and fractional flow reserve versus single-photon emission computed tomographic myocardial perfusion imaging for determining lesion significance in patients with multivessel coronary disease Am J Cardiol 99 2007 896 902
17. CW Nam, F Mangiacapra, R Entjes et al. Functional SYNTAX score for risk assessment in multivessel coronary artery disease J Am Coll Cardiol 58 2011 1211 1218
18. J Li, MY Elrashidi, AJ Flammer et al. Long-term outcomes of fractional flow reserve-guided vs. angiography-guided percutaneous coronary intervention in contemporary practice Eur Heart J 34 2013 1375 1383
19. NH Pijls, P van Schaardenburgh, G Manoharan et al. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER Study J Am Coll Cardiol 49 2007 2105 2111
20. GD Dangas, PW Serruys, DJ Kereiakes et al. Meta-analysis of everolimus-eluting versus paclitaxel-eluting stents in coronary artery disease: final 3-year results of the SPIRIT clinical trials program (Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) JACC Cardiovasc Interv 6 2013 914 922
21. S Silber, S Windecker, P Vranckx et al. Unrestricted randomised use of two new generation drug-eluting coronary stents: 2-year patient-related versus stent-related outcomes from the RESOLUTE All Comers trial Lancet 377 2011 1241 1247
22. GW Stone, A Rizvi, W Newman et al. Everolimus-eluting versus paclitaxel-eluting stents in coronary artery disease N Engl J Med 362 2010 1663 1674