Predicting outcome in the COURAGE trial (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation): Coronary anatomy versus ischemia

JACC: Cardiovascular Interventions

Volumn 7, Issue 2, 2014, Pages 195-201

  Mancini, G B John ^a   Hartigan, Pamela M ^b   Shaw, Leslee J ^c   Berman, Daniel S ^d   Hayes, Sean W ^d   Bates, Eric R ^e   Maron, David J ^f   Teo, Koon ^g   Sedlis, Steven P ^h   Chaitman, Bernard R ⁱ   Weintraub, William S ^j   Spertus, John A ^k   Kostuk, William J ^l   Dada, Marcin ^m   Booth, David C ⁿ   Boden, William E ^o  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^f VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^g MCMASTER UNIVERSITY MEDICAL CENTRE   (Canada)

^h NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ SAINT LOUIS UNIVERSITY HOSPITAL   (United States)

^j CHRISTIANA CARE HEALTH SYSTEM   (United States)

^k UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^l UNIVERSITY OF WESTERN ONTARIO   (Canada)

^m HARTFORD HOSPITAL   (United States)

ⁿ UNIVERSITY OF KENTUCKY   (United States)

^o UNIVERSITY AT BUFFALO   (United States)

more..

Author keywords

angiographic burden; coronary angiography; ischemia; ischemic burden; nuclear perfusion imaging; stable ischemic heart disease

Indexed keywords

ANGIOGRAPHIC BURDEN; CORONARY ANGIOGRAPHY; ISCHEMIA; ISCHEMIC BURDEN; NUCLEAR PERFUSION IMAGING; STABLE ISCHEMIC HEART DISEASE;

AGED; CARDIOVASCULAR AGENTS; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; CORONARY CIRCULATION; CORONARY VESSELS; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIAL PERFUSION IMAGING; PERCUTANEOUS CORONARY INTERVENTION; PREDICTIVE VALUE OF TESTS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STROKE VOLUME; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT;

HIGH DENSITY LIPOPROTEIN;

ADULT; ANATOMIC LANDMARK; ANGIOCARDIOGRAPHY; ARTICLE; CLINICAL EVALUATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEATH; DIABETES MELLITUS; FEMALE; FOLLOW UP; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE ISCHEMIA; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NON ST SEGMENT ELEVATION ACUTE CORONARY SYNDROME; OPTIMAL MEDICAL THERAPY; OUTCOME ASSESSMENT; PATIENT HISTORY OF CORONARY ARTERY BYPASS GRAFT; PERCUTANEOUS CORONARY INTERVENTION; PREDICTION; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THERAPY;

EID: 84894387586     PISSN: 19368798     EISSN: 18767605     Source Type: Journal    
DOI: 10.1016/j.jcin.2013.10.017     Document Type: Article

References (19)

1. S.D. Fihn, J.M. Gardin, J. Abrams American College of Cardiology Foundation, American Heart Association Task Force on Practice Guidelines, American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: executive summary J Am Coll Cardiol 60 2012 e44 e164
2. W.E. Boden, R.A. O'Rourke, and K.K. Teo et al. Optimal medical therapy with or without PCI for stable coronary disease N Engl J Med 356 2007 1503 1516
3. L.J. Shaw, D.S. Berman, and D.J. Maron et al. Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: Results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy Circulation 117 2008 1283 1291
4. L.J. Shaw, W.S. Weintraub, and D.J. Maron et al. Baseline stress myocardial perfusion imaging results and outcomes in patients with stable ischemic heart disease randomized to optimal medical therapy with or without percutaneous coronary intervention Am Heart J 164 2012 243 250
5. G.B.J. Mancini, E.R. Bates, and D.J. Maron et al. Quantitative results of baseline angiography and percutaneous coronary intervention in the COURAGE trial Circ Cardiovasc Qual Outcomes 2 2009 320 327
6. G.B. Mancini, P.M. Hartigan, E.R. Bates COURAGE Investigators and Coordinators Angiographic disease progression and residual risk of cardiovascular events while on optimal medical therapy: observations from the COURAGE Trial Circ Cardiovasc Interv 4 2011 545 552
7. G.B.J. Mancini, P.M. Hartigan, and E.R. Bates et al. Prognostic importance of coronary anatomy and left ventricular ejection fraction despite optimal therapy: assessment of residual risk in the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation Trial Am Heart J 166 2013 481 487
8. P.J. Slomka, H. Nishina, and D.S. Berman et al. Automated quantification of myocardial perfusion SPECT using simplified normal limits J Nucl Cardiol 12 2005 66 77
9. J.A. Panza, T.A. Holly, and F.M. Asch et al. Inducible myocardial ischemia and outcomes in patients with coronary artery disease and left ventricular dysfunction J Am Coll Cardiol 61 2013 1860 1870
10. L.J. Shaw, M.D. Cerqueira, and M.M. Brooks et al. Impact of left ventricular function and the extent of ischemia and scar by stress myocardial perfusion imaging on prognosis and therapeutic risk reduction in diabetic patients with coronary artery disease: results from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial J Nucl Cardiol 19 2012 658 669
11. R.O. Bonow, K.M. Kent, and D.R. Rosing et al. Exercise-induced ischemia in mildly symptomatic patients with coronary artery disease and preserved left ventricular function. Identification of subgroups at risk of death during medical therapy N Engl J Med 311 1984 1339 1345
12. D.A. Weiner, T.J. Ryan, and C.H. McCabe et al. The role of exercise testing in identifying patients with improved survival after coronary artery bypass surgery J Am Coll Cardiol 8 1986 741 748
13. R. Hachamovitch, D.S. Berman, and L.J. Shaw et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction Circulation 97 1998 535 543
14. R. Hachamovitch Risk assessment of patients with known or suspected CAD using stress myocardial perfusion SPECT. Part I: the ongoing evolution of clinical evidence Rev Cardiovasc Med 1 2000 91 102
15. R. Hachamovitch, S.W. Hayes, and J.D. Friedman et al. Comparison of the short-term survival benefit associated with revascularization compared with medical therapy in patients with no prior coronary artery disease undergoing stress myocardial perfusion single photon emission computed tomography Circulation 107 2003 2900 2907
16. A.K. Gehi, S. Ali, and B. Na et al. Inducible ischemia and the risk of recurrent cardiovascular events in outpatients with stable coronary heart disease: the heart and soul study Arch Intern Med 168 2008 1423 1428
17. R. Hachamovitch, A. Rozanski, and L.J. Shaw et al. Impact of ischemia and scar on the therapeutic benefit derived from myocardial revascularization vs. medical therapy among patients undergoing stress-rest myocardial perfusion scintigraphy Eur Heart J 32 2011 1012 1024
18. L.J. Shaw, G.V. Heller, and P. Casperson et al. Gated myocardial perfusion single photon emission computed tomography in the clinical outcomes utilizing revascularization and aggressive drug evaluation (COURAGE) trial J Nucl Cardiol 13 2006 685 698
19. R.G. Schwartz, T.A. Pearson, and V.G. Kalaria et al. Prospective serial evaluation of myocardial perfusion and lipids during the first six months of pravastatin therapy: coronary artery disease regression single photon emission computed tomography monitoring trial J Am Coll Cardiol 42 2003 600 610