-
1
-
-
77957664665
-
Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: A randomised, open-label, phase 3 trial
-
M. Hallek, K. Fischer, G. Fingerle-Rowson, and et al. Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial Lancet 376 2010 1164 1174
-
(2010)
Lancet
, vol.376
, pp. 1164-1174
-
-
Hallek, M.1
Fischer, K.2
Fingerle-Rowson, G.3
-
2
-
-
79951893501
-
Optimal pharmacotherapeutic management of chronic lymphocytic leukaemia: Considerations in the elderly
-
V. Goede, and M. Hallek Optimal pharmacotherapeutic management of chronic lymphocytic leukaemia: considerations in the elderly Drugs Aging 28 2011 163 176
-
(2011)
Drugs Aging
, vol.28
, pp. 163-176
-
-
Goede, V.1
Hallek, M.2
-
3
-
-
0034727833
-
Genomic aberrations and survival in chronic lymphocytic leukemia
-
H. Dohner, S. Stilgenbauer, A. Benner, and et al. Genomic aberrations and survival in chronic lymphocytic leukemia N Engl J Med 343 2000 1910 1916
-
(2000)
N Engl J Med
, vol.343
, pp. 1910-1916
-
-
Dohner, H.1
Stilgenbauer, S.2
Benner, A.3
-
4
-
-
84908556992
-
A new hope: Novel therapeutic approaches to treatment of chronic lymphocytic leukaemia with defects in TP53
-
P. Shindiapina, J.R. Brown, and A.V. Danilov A new hope: novel therapeutic approaches to treatment of chronic lymphocytic leukaemia with defects in TP53 Br J Haematol 167 2014 149 161
-
(2014)
Br J Haematol
, vol.167
, pp. 149-161
-
-
Shindiapina, P.1
Brown, J.R.2
Danilov, A.V.3
-
5
-
-
84896323847
-
Treatment of older patients with chronic lymphocytic leukemia: Key questions and current answers
-
T. Shanafelt Treatment of older patients with chronic lymphocytic leukemia: key questions and current answers Hematol Am Soc Hematol Educ Program 2013 2013 158 167
-
(2013)
Hematol Am Soc Hematol Educ Program
, vol.2013
, pp. 158-167
-
-
Shanafelt, T.1
-
6
-
-
84924378553
-
Frontline chemoimmunotherapy with fludarabine (F), cyclophosphamide (C), and rituximab (R) (FCR) shows superior efficacy in comparison to bendamustine (B) and rituximab (BR) in previously untreated and physically fit patients (pts) with advanced chronic lymphocytic leukemia (CLL): Final analysis of an international, randomized study of the German CLL Study Group (GCLLSG) (CLL10 Study)
-
Eichhorst B, Fink A, Busch R, et al. Frontline chemoimmunotherapy with fludarabine (F), cyclophosphamide (C), and rituximab (R) (FCR) shows superior efficacy in comparison to bendamustine (B) and rituximab (BR) in previously untreated and physically fit patients (pts) with advanced chronic lymphocytic leukemia (CLL): final analysis of an international, randomized study of the German CLL Study Group (GCLLSG) (CLL10 Study). American Society of Hematology Annual Meeting Abstracts 2014:19.
-
(2014)
American Society of Hematology Annual Meeting Abstracts
, pp. 19
-
-
Eichhorst, B.1
Fink, A.2
Busch, R.3
-
7
-
-
34447530283
-
Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 trial): A randomised controlled trial
-
D. Catovsky, S. Richards, E. Matutes, and et al. Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 trial): a randomised controlled trial Lancet 370 2007 230 239
-
(2007)
Lancet
, vol.370
, pp. 230-239
-
-
Catovsky, D.1
Richards, S.2
Matutes, E.3
-
8
-
-
70349330220
-
Phase III randomized study of bendamustine compared with chlorambucil in previously untreated patients with chronic lymphocytic leukemia
-
W.U. Knauf, T. Lissichkov, A. Aldaoud, and et al. Phase III randomized study of bendamustine compared with chlorambucil in previously untreated patients with chronic lymphocytic leukemia J Clin Oncol 27 2009 4378 4384
-
(2009)
J Clin Oncol
, vol.27
, pp. 4378-4384
-
-
Knauf, W.U.1
Lissichkov, T.2
Aldaoud, A.3
-
9
-
-
84870734255
-
Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia
-
A. Wiestner Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia Blood 120 2012 4684 4691
-
(2012)
Blood
, vol.120
, pp. 4684-4691
-
-
Wiestner, A.1
-
10
-
-
70349562920
-
Molecular and cellular mechanisms of CLL: Novel therapeutic approaches
-
L. Pleyer, A. Egle, T.N. Hartmann, and et al. Molecular and cellular mechanisms of CLL: novel therapeutic approaches Nat Rev Clin Oncol 6 2009 405 418
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 405-418
-
-
Pleyer, L.1
Egle, A.2
Hartmann, T.N.3
-
11
-
-
84882260238
-
Mechanisms of action of CD20 antibodies
-
P. Boross, and J.H. Leusen Mechanisms of action of CD20 antibodies Am J Cancer Res 2 2012 676 690
-
(2012)
Am J Cancer Res
, vol.2
, pp. 676-690
-
-
Boross, P.1
Leusen, J.H.2
-
12
-
-
84882997049
-
Anti-tumor activity of obinutuzumab and rituximab in a follicular lymphoma 3D model
-
E. Decaup, C. Jean, C. Laurent, and et al. Anti-tumor activity of obinutuzumab and rituximab in a follicular lymphoma 3D model Blood Cancer J 3 2013 e131
-
(2013)
Blood Cancer J
, vol.3
, pp. e131
-
-
Decaup, E.1
Jean, C.2
Laurent, C.3
-
13
-
-
84885671483
-
Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft models
-
S. Herter, F. Herting, O. Mundigl, and et al. Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft models Mol Cancer Ther 12 2013 2031 2042
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 2031-2042
-
-
Herter, S.1
Herting, F.2
Mundigl, O.3
-
14
-
-
84867236304
-
Novel CD20 monoclonal antibodies for lymphoma therapy
-
S. Cang, N. Mukhi, K. Wang, and et al. Novel CD20 monoclonal antibodies for lymphoma therapy J Hematol Oncol 5 2012 64
-
(2012)
J Hematol Oncol
, vol.5
, pp. 64
-
-
Cang, S.1
Mukhi, N.2
Wang, K.3
-
15
-
-
77953507105
-
The future of CD20 monoclonal antibody therapy in B-cell malignancies
-
M.S. Czuczman, and S.A. Gregory The future of CD20 monoclonal antibody therapy in B-cell malignancies Leuk Lymphoma 51 2010 983 994
-
(2010)
Leuk Lymphoma
, vol.51
, pp. 983-994
-
-
Czuczman, M.S.1
Gregory, S.A.2
-
16
-
-
79955979273
-
Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies
-
W. Alduaij, A. Ivanov, J. Honeychurch, and et al. Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies Blood 117 2011 4519 4529
-
(2011)
Blood
, vol.117
, pp. 4519-4529
-
-
Alduaij, W.1
Ivanov, A.2
Honeychurch, J.3
-
17
-
-
84859833070
-
Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway
-
J. Honeychurch, W. Alduaij, M. Azizyan, and et al. Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway Blood 119 2012 3523 3533
-
(2012)
Blood
, vol.119
, pp. 3523-3533
-
-
Honeychurch, J.1
Alduaij, W.2
Azizyan, M.3
-
18
-
-
84894552888
-
Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions
-
V. Goede, K. Fischer, R. Busch, and et al. Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions N Engl J Med 370 2014 1101 1110
-
(2014)
N Engl J Med
, vol.370
, pp. 1101-1110
-
-
Goede, V.1
Fischer, K.2
Busch, R.3
-
19
-
-
84937023635
-
Obinutuzumab as frontline treatment of chronic lymphocytic leukemia: Updated results of the CLL11 study
-
V. Goede, K. Fischer, A. Engelke, and et al. Obinutuzumab as frontline treatment of chronic lymphocytic leukemia: updated results of the CLL11 study Leukemia 29 2015 1602 1604
-
(2015)
Leukemia
, vol.29
, pp. 1602-1604
-
-
Goede, V.1
Fischer, K.2
Engelke, A.3
-
20
-
-
84929505415
-
Chlorambucil plus ofatumumab versus chlorambucil alone in previously untreated patients with chronic lymphocytic leukaemia (COMPLEMENT 1): A randomised, multicentre, open-label phase 3 trial
-
P. Hillmen, T. Robak, A. Janssens, and et al. Chlorambucil plus ofatumumab versus chlorambucil alone in previously untreated patients with chronic lymphocytic leukaemia (COMPLEMENT 1): a randomised, multicentre, open-label phase 3 trial Lancet 385 2015 1873 1883
-
(2015)
Lancet
, vol.385
, pp. 1873-1883
-
-
Hillmen, P.1
Robak, T.2
Janssens, A.3
-
21
-
-
77950478885
-
Rituximab plus fludarabine and cyclophosphamide prolongs progression-free survival compared with fludarabine and cyclophosphamide alone in previously treated chronic lymphocytic leukemia
-
T. Robak, A. Dmoszynska, P. Solal-Céligny, and et al. Rituximab plus fludarabine and cyclophosphamide prolongs progression-free survival compared with fludarabine and cyclophosphamide alone in previously treated chronic lymphocytic leukemia J Clin Oncol 28 2010 1756 1765
-
(2010)
J Clin Oncol
, vol.28
, pp. 1756-1765
-
-
Robak, T.1
Dmoszynska, A.2
Solal-Céligny, P.3
-
22
-
-
84893472705
-
The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells
-
S. Fiorcari, W.S. Brown, B.W. McIntyre, and et al. The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells PLoS One 8 2013 e83830
-
(2013)
PLoS One
, vol.8
, pp. e83830
-
-
Fiorcari, S.1
Brown, W.S.2
McIntyre, B.W.3
-
23
-
-
84896692766
-
Idelalisib and rituximab in relapsed chronic lymphocytic leukemia
-
R.R. Furman, J.P. Sharman, S.E. Coutre, and et al. Idelalisib and rituximab in relapsed chronic lymphocytic leukemia N Engl J Med 370 2014 997 1007
-
(2014)
N Engl J Med
, vol.370
, pp. 997-1007
-
-
Furman, R.R.1
Sharman, J.P.2
Coutre, S.E.3
-
24
-
-
84947028918
-
Health-related quality of life (HRQL) impact of idelalisib in patients with relapsed chronic lymphocytic leukemia: Phase 3 results [abstract P252]
-
Paper presented at
-
Eradat HA, Ghia P, O'Brien SM, et al. Health-related quality of life (HRQL) impact of idelalisib in patients with relapsed chronic lymphocytic leukemia: phase 3 results [abstract P252]. Paper presented at: 19th Congress of the European Hematology Association; June 12-15, 2014 in Milan, Italy.
-
19th Congress of the European Hematology Association; June 12-15, 2014 in Milan, Italy
-
-
Eradat, H.A.1
Ghia, P.2
O'Brien, S.M.3
-
25
-
-
84947040652
-
Second interim analysis of a phase 3 study evaluating idelalisib and rituximab for relapsed CLL [abstract S704]
-
Paper presented at
-
Coutre SE, Furman RR, Sharman JP, et al. Second interim analysis of a phase 3 study evaluating idelalisib and rituximab for relapsed CLL [abstract S704]. Paper presented at: 19th Congress of the European Hematology Association; June 12-15, 2014 in Milan, Italy.
-
19th Congress of the European Hematology Association; June 12-15, 2014 in Milan, Italy
-
-
Coutre, S.E.1
Furman, R.R.2
Sharman, J.P.3
-
26
-
-
84947029238
-
Efficacy of idelalisib in CLL subpopulations harboring del(17p) and other adverse prognostic factors: Results from a phase 3, randomized, double-blind, placebo-controlled trial [abstract S1341]
-
Paper presented at
-
Stilgenbauer S, Coutre SE, Furman RR, et al. Efficacy of idelalisib in CLL subpopulations harboring del(17p) and other adverse prognostic factors: results from a phase 3, randomized, double-blind, placebo-controlled trial [abstract S1341]. Paper presented at: 19th Congress of the European Hematology Association; June 12-15, 2014 in Milan, Italy.
-
19th Congress of the European Hematology Association; June 12-15, 2014 in Milan, Italy
-
-
Stilgenbauer, S.1
Coutre, S.E.2
Furman, R.R.3
-
27
-
-
84924659807
-
Update on a phase 2 study of idelalisib in combination with rituximab in treatment-naive patients ≥ 65 years with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL)
-
S. O'Brien, N. Lamanna, T.J. Kipps, and et al. Update on a phase 2 study of idelalisib in combination with rituximab in treatment-naive patients ≥ 65 years with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) Blood 124 2014 1994
-
(2014)
Blood
, vol.124
, pp. 1994
-
-
O'Brien, S.1
Lamanna, N.2
Kipps, T.J.3
-
28
-
-
79959404661
-
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
-
S.E. Herman, A.L. Gordon, E. Hertlein, and et al. Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765 Blood 117 2011 6287 6296
-
(2011)
Blood
, vol.117
, pp. 6287-6296
-
-
Herman, S.E.1
Gordon, A.L.2
Hertlein, E.3
-
29
-
-
84858636448
-
The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia
-
M.F. de Rooij, A. Kuil, C.R. Geest, and et al. The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia Blood 119 2012 2590 2594
-
(2012)
Blood
, vol.119
, pp. 2590-2594
-
-
De Rooij, M.F.1
Kuil, A.2
Geest, C.R.3
-
30
-
-
84879748062
-
Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia
-
J.C. Byrd, R.R. Furman, S.E. Coutre, and et al. Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia N Engl J Med 369 2013 32 42
-
(2013)
N Engl J Med
, vol.369
, pp. 32-42
-
-
Byrd, J.C.1
Furman, R.R.2
Coutre, S.E.3
-
31
-
-
84904252369
-
Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia
-
J.C. Byrd, J.R. Brown, S. O'Brien, and et al. Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia N Engl J Med 371 2014 213 223
-
(2014)
N Engl J Med
, vol.371
, pp. 213-223
-
-
Byrd, J.C.1
Brown, J.R.2
O'Brien, S.3
-
32
-
-
84924378557
-
Updated efficacy including genetic and clinical subgroup analysis and overall safety in the phase 3 RESONATE trial of ibrutinib versus ofatumumab in previously treated chronic lymphocytic leukemia/small lymphocytic lymphoma
-
J.R. Brown, P. Hillmen, S. O'Brien, and et al. Updated efficacy including genetic and clinical subgroup analysis and overall safety in the phase 3 RESONATE trial of ibrutinib versus ofatumumab in previously treated chronic lymphocytic leukemia/small lymphocytic lymphoma Blood 124 2014 3331
-
(2014)
Blood
, vol.124
, pp. 3331
-
-
Brown, J.R.1
Hillmen, P.2
O'Brien, S.3
-
33
-
-
77950502126
-
Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia
-
W.G. Wierda, T.J. Kipps, J. Mayer, and et al. Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia J Clin Oncol 28 2010 1749 1755
-
(2010)
J Clin Oncol
, vol.28
, pp. 1749-1755
-
-
Wierda, W.G.1
Kipps, T.J.2
Mayer, J.3
-
34
-
-
84891373281
-
Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: An open-label, multicentre, phase 1b/2 trial
-
S. O'Brien, R.R. Furman, S.E. Coutre, and et al. Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial Lancet Oncol 15 2014 48 58
-
(2014)
Lancet Oncol
, vol.15
, pp. 48-58
-
-
O'Brien, S.1
Furman, R.R.2
Coutre, S.E.3
-
35
-
-
84927583205
-
Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation
-
S. Kamel, L. Horton, L. Ysebaert, and et al. Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation Leukemia 29 2015 783 787
-
(2015)
Leukemia
, vol.29
, pp. 783-787
-
-
Kamel, S.1
Horton, L.2
Ysebaert, L.3
-
36
-
-
84919494922
-
Ibrutinib treatment affects collagen and von Willebrand factor-dependent platelet functions
-
M. Levade, E. David, C. Garcia, and et al. Ibrutinib treatment affects collagen and von Willebrand factor-dependent platelet functions Blood 124 2014 3991 3995
-
(2014)
Blood
, vol.124
, pp. 3991-3995
-
-
Levade, M.1
David, E.2
Garcia, C.3
-
38
-
-
84873540049
-
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
-
A.J. Souers, J.D. Leverson, E.R. Boghaert, and et al. ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets Nat Med 19 2013 202 208
-
(2013)
Nat Med
, vol.19
, pp. 202-208
-
-
Souers, A.J.1
Leverson, J.D.2
Boghaert, E.R.3
-
39
-
-
84897387048
-
Targeting the mitochondrial apoptotic pathway: A preferred approach in hematologic malignancies?
-
K. Brinkmann, and H. Kashkar Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies? Cell Death Dis 5 2014 e1098
-
(2014)
Cell Death Dis
, vol.5
, pp. e1098
-
-
Brinkmann, K.1
Kashkar, H.2
-
40
-
-
84896479968
-
Bcl-2 inhibitor ABT-199 (GDC-0199) monotherapy shows anti-aumor activity including complete remissions in high-risk relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL)
-
J.F. Seymour, M.S. Davids, J.M. Pagel, and et al. Bcl-2 inhibitor ABT-199 (GDC-0199) monotherapy shows anti-aumor activity including complete remissions in high-risk relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) Blood 122 2013 872
-
(2013)
Blood
, vol.122
, pp. 872
-
-
Seymour, J.F.1
Davids, M.S.2
Pagel, J.M.3
-
41
-
-
84925484937
-
Determination of recommended phase 2 dose of ABT-199 (GDC-0199) combined with rituximab (R) in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL)
-
A.W. Roberts, S. Ma, D.M. Brander, and et al. Determination of recommended phase 2 dose of ABT-199 (GDC-0199) combined with rituximab (R) in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) Blood 124 2014 325
-
(2014)
Blood
, vol.124
, pp. 325
-
-
Roberts, A.W.1
Ma, S.2
Brander, D.M.3
-
42
-
-
84947032316
-
ABT-199 (GDC-0199) combined with rituximab in patients with relapsed/refractory chronic lymphocyitc leukemia: Interim results of a phase 1b study [abstract S703]
-
Paper presented at
-
Roberts AW, Ma S, Brander D, et al. ABT-199 (GDC-0199) combined with rituximab in patients with relapsed/refractory chronic lymphocyitc leukemia: interim results of a phase 1b study [abstract S703]. Paper presented at: 19th Congress of the European Hematology Association; June 12-15, 2014 in Milan, Italy.
-
19th Congress of the European Hematology Association; June 12-15, 2014 in Milan, Italy
-
-
Roberts, A.W.1
Ma, S.2
Brander, D.3
-
43
-
-
84888219144
-
PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models
-
D.G. Winkler, K.L. Faia, J.P. DiNitto, and et al. PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models Chem Biol 20 2013 1364 1374
-
(2013)
Chem Biol
, vol.20
, pp. 1364-1374
-
-
Winkler, D.G.1
Faia, K.L.2
DiNitto, J.P.3
-
44
-
-
84924664474
-
Duvelisib (IPI-145), a PI3K-δ,γ inhibitor, is clinically active in patients with relapsed/refractory chronic lymphocytic leukemia
-
S. O'Brien, M. Patel, B.S. Kahl, and et al. Duvelisib (IPI-145), a PI3K-δ,γ inhibitor, is clinically active in patients with relapsed/refractory chronic lymphocytic leukemia Blood 124 2014 3334
-
(2014)
Blood
, vol.124
, pp. 3334
-
-
O'Brien, S.1
Patel, M.2
Kahl, B.S.3
-
45
-
-
84860630561
-
Minimal residual disease quantification is an independent predictor of progression-free and overall survival in chronic lymphocytic leukemia: A multivariate analysis from the randomized GCLLSG CLL8 trial
-
S. Böttcher, M. Ritgen, K. Fischer, and et al. Minimal residual disease quantification is an independent predictor of progression-free and overall survival in chronic lymphocytic leukemia: a multivariate analysis from the randomized GCLLSG CLL8 trial J Clin Oncol 30 2012 980 988
-
(2012)
J Clin Oncol
, vol.30
, pp. 980-988
-
-
Böttcher, S.1
Ritgen, M.2
Fischer, K.3
-
46
-
-
84897490051
-
How will B-cell-receptor-targeted therapies change future CLL therapy?
-
J.A. Jones, and J.C. Byrd How will B-cell-receptor-targeted therapies change future CLL therapy? Blood 123 2014 1455 1460
-
(2014)
Blood
, vol.123
, pp. 1455-1460
-
-
Jones, J.A.1
Byrd, J.C.2
-
47
-
-
84902183019
-
Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib
-
J.A. Woyach, R.R. Furman, T.M. Liu, and et al. Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib N Engl J Med 370 2014 2286 2294
-
(2014)
N Engl J Med
, vol.370
, pp. 2286-2294
-
-
Woyach, J.A.1
Furman, R.R.2
Liu, T.M.3
-
48
-
-
84924378560
-
Complex karyotype, rather than del(17p), is associated with inferior outcomes in relapsed or refractory CLL patients treated with ibrutinib-based regimens
-
P.A. Thompson, W.G. Wierda, A. Ferrajoli, and et al. Complex karyotype, rather than del(17p), is associated with inferior outcomes in relapsed or refractory CLL patients treated with ibrutinib-based regimens Blood 124 2014 22
-
(2014)
Blood
, vol.124
, pp. 22
-
-
Thompson, P.A.1
Wierda, W.G.2
Ferrajoli, A.3
-
49
-
-
84994504370
-
Etiology of ibrutinib therapy discontinuation and outcomes in patients with chronic lymphocytic leukemia
-
K.J. Maddocks, A.S. Ruppert, G. Lozanski, and et al. Etiology of ibrutinib therapy discontinuation and outcomes in patients with chronic lymphocytic leukemia JAMA Oncol 1 2015 80 87
-
(2015)
JAMA Oncol
, vol.1
, pp. 80-87
-
-
Maddocks, K.J.1
Ruppert, A.S.2
Lozanski, G.3
-
50
-
-
84902590340
-
Eradication of bone marrow minimal residual disease may prompt early treatment discontinuation in CLL
-
P. Strati, M.J. Keating, S.M. O'Brien, and et al. Eradication of bone marrow minimal residual disease may prompt early treatment discontinuation in CLL Blood 123 2014 3727 3732
-
(2014)
Blood
, vol.123
, pp. 3727-3732
-
-
Strati, P.1
Keating, M.J.2
O'Brien, S.M.3
-
51
-
-
84927732048
-
Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib
-
J.C. Byrd, R.R. Furman, S.E. Coutre, and et al. Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib Blood 125 2015 2497 2506
-
(2015)
Blood
, vol.125
, pp. 2497-2506
-
-
Byrd, J.C.1
Furman, R.R.2
Coutre, S.E.3
-
52
-
-
84919469417
-
Managing high-risk CLL during transition to a new treatment era: Stem cell transplantation or novel agents?
-
P. Dreger, J. Schetelig, N. Andersen, and et al. Managing high-risk CLL during transition to a new treatment era: stem cell transplantation or novel agents? Blood 124 2014 3841 3849
-
(2014)
Blood
, vol.124
, pp. 3841-3849
-
-
Dreger, P.1
Schetelig, J.2
Andersen, N.3
|