Proteinase 3 Induces Neuronal Cell Death Through Microglial Activation

Neurochemical Research

Volumn 40, Issue 11, 2015, Pages 2242-2251

  Cho, Kyu Suk ^a   Lee, Eun Joo ^a   Kim, Jung Nam ^a   Choi, Ji Woong ^b   Kim, Hahn Young ^a   Han, Seol Heui ^a   Ryu, Jong Hoon ^c   Cheong, Jae Hoon ^d   Shin, Chan Young ^a   Kwon, Kyoung Ja ^a  

^a Konkuk University School of Medicine   (South Korea)

^b Gachon University   (South Korea)

^c Kyung Hee University   (South Korea)

^d Sahmyook University   (South Korea)

Author keywords

Glial activation; Neuroinflammation; Neuronal death; PR3; ROS

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCLONAL ANTIBODY; MYELOBLASTIN; PROTEINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; CYTOKINE; NEUTRALIZING ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL LEVEL; CONTROLLED STUDY; CORPUS STRIATUM; CYTOKINE PRODUCTION; EMBRYO; ENZYME ACTIVITY; FEMALE; IN VIVO STUDY; MALE; MICROGLIA; MOLECULAR PATHOLOGY; NERVE CELL NECROSIS; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN CORTEX; CELL DEATH; CHEMICALLY INDUCED; DRUG EFFECTS; INFLAMMATION; MACROPHAGE ACTIVATION; METABOLISM; MICROINJECTION; NERVE CELL; PATHOLOGY; PRIMARY CELL CULTURE; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; CELL DEATH; CEREBRAL CORTEX; CORPUS STRIATUM; CYTOKINES; INFLAMMATION; MACROPHAGE ACTIVATION; MALE; MICROGLIA; MICROINJECTIONS; MYELOBLASTIN; NEURONS; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 84947029966     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-015-1714-y     Document Type: Article

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