Metformin prevents cancer metastasis by inhibiting M2-like polarization of tumor associated macrophages

Oncotarget

Volumn 6, Issue 34, 2015, Pages 36441-36455

  Ding, Ling ^a   Liang, Guikai ^a   Yao, Zhangting ^a   Zhang, Jieqiong ^a   Liu, Ruiyang ^a   Chen, Huihui ^a   Zhou, Yulu ^a   Wu, Honghai ^a   Yang, Bo ^a   He, Qiaojun ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

AMPK 1; Cancer metastasis; Macrophage polarization; Metformin

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; AMPK ALPHA1 PROTEIN; CD206 ANTIGEN; CLODRONIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERLEUKIN 13; MARKER; MESSENGER RNA; METFORMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CAPILLARY ENDOTHELIAL CELL; CELL POLARITY; CONTROLLED STUDY; IN VITRO STUDY; LEWIS CARCINOMA; LUNG METASTASIS; METASTASIS INHIBITION; MIGRATION INHIBITION; MOUSE; NONHUMAN; PERICYTE; TUMOR ASSOCIATED LEUKOCYTE; ANIMAL; C57BL MOUSE; CARCINOMA, LEWIS LUNG; DRUG EFFECTS; MACROPHAGE; METABOLISM; NEOPLASM METASTASIS; PATHOLOGY; RAW 264.7 CELL LINE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; CELL POLARITY; MACROPHAGES; METFORMIN; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; RAW 264.7 CELLS; SIGNAL TRANSDUCTION;

EID: 84946854646     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5541     Document Type: Article

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