Transgenerational inheritance of enhanced susceptibility to radiation-induced medulloblastoma in newborn Ptch1+/- mice after paternal irradiation

Oncotarget

Volumn 6, Issue 34, 2015, Pages 36098-36112

  Paris, Lorena ^a,b   Giardullo, Paola ^c,d   Leonardi, Simona ^a   Tanno, Barbara ^a   Meschini, Roberta ^b   Cordelli, Eugenia ^a   Benassi, Barbara ^a   Longobardi, Maria Grazia ^e   Izzotti, Alberto ^e,f   Pulliero, Alessandra ^e   Mancuso, Mariateresa ^a   Pacchierotti, Francesca ^a  

^a ENEA   (Italy)

^b UNIVERSITY OF TUSCIA   (Italy)

^c GUGLIELMO MARCONI UNIVERSITY   (Italy)

^d ROMA TRE UNIVERSITY   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

^f UNIVERSITY OF GENOA   (Italy)

Author keywords

Epigenetic inheritance; Medulloblastoma; microRNA; Patched1 knockout mice; Transgenerational carcinogenesis

Indexed keywords

DNA; MICRORNA; PROTEIN PATCHED 1; CELL SURFACE RECEPTOR; PROTEIN PATCHED; PTCH1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EPIGENETICS; FEMALE; GENE LOSS; GERM CELL; GRANULE CELL; HETEROZYGOSITY LOSS; INHERITANCE; INTERSTITIAL CHROMOSOME DELETION; MALE; MEDULLOBLASTOMA; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEWBORN; NONHUMAN; RADIATION CARCINOGENESIS; RADIATION EXPOSURE; RADIATION INDUCED NEOPLASM; SPERMATOGONIUM; TRANSGENERATIONAL INHERITANCE; X IRRADIATION; ANIMAL; CEREBELLAR NEOPLASMS; COMET ASSAY; GENETICS; MICROARRAY ANALYSIS; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; CEREBELLAR NEOPLASMS; COMET ASSAY; FEMALE; MALE; MEDULLOBLASTOMA; MICE; MICE, TRANSGENIC; MICROARRAY ANALYSIS; NEOPLASMS, RADIATION-INDUCED; PATCHED RECEPTORS; PATCHED-1 RECEPTOR; RECEPTORS, CELL SURFACE;

EID: 84946854572     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5553     Document Type: Article

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