메뉴 건너뛰기




Volumn 867, Issue , 2015, Pages 125-143

Neuron-specifi c enolase as a biomarker: Biochemical and clinical aspects

Author keywords

ENO1; ENO2; ENO3; Neuron specifi c enolase (NSE); NSE as biomarker; NSE assays in body fl uids; NSE biochemical properties; NSE clinical indications; NSE in brain damage; NSE in gastroenteropancreatic neuroendocrine tumours; NSE in lung cancer; NSE in melanoma; NSE in neuroblastoma; NSE in neuroendocrine tumours; NSE in seminoma; NSE mapping and gene function; Tissue NSE expression

Indexed keywords

NEURON SPECIFIC ENOLASE; ENOLASE; TUMOR MARKER;

EID: 84946781904     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-94-017-7215-0_9     Document Type: Chapter
Times cited : (412)

References (127)
  • 1
    • 78651184259 scopus 로고
    • Chromatographic and electrophoretic fractionation of soluble proteins of brain and liver
    • Moore BW, McGregor T (1965) Chromatographic and electrophoretic fractionation of soluble proteins of brain and liver. J Biol Chem 240:1647–1653
    • (1965) J Biol Chem , vol.240 , pp. 1647-1653
    • Moore, B.W.1    McGregor, T.2
  • 2
    • 0017228425 scopus 로고
    • Immunocytochemical localization of nervous system specifi c protein (NSP-R) in rat brain
    • Pickel VM, Reis DJ, Marangos PJ et al (1976) Immunocytochemical localization of nervous system specifi c protein (NSP-R) in rat brain. Brain Res 105:184–187
    • (1976) Brain Res , vol.105 , pp. 184-187
    • Pickel, V.M.1    Reis, D.J.2    Marangos, P.J.3
  • 3
    • 84982070871 scopus 로고
    • Demonstration of enolase activity connected to the brainspecifi c protein 14-3-2
    • Bock E, Dissing J (1975) Demonstration of enolase activity connected to the brainspecifi c protein 14-3-2 Scand J Immunol 4(suppl 2):31–36
    • (1975) Scand J Immunol , vol.4 , pp. 31-36
    • Bock, E.1    Dissing, J.2
  • 4
    • 0017264721 scopus 로고
    • Determination and characterization of neuron specifi c protein (NSP) associated enolase activity
    • Marangos PJ, Zomzely-Neurath C, York C (1976) Determination and characterization of neuron specifi c protein (NSP) associated enolase activity. Biochem Biophys Res Commun 68:1309–1316
    • (1976) Biochem Biophys Res Commun , vol.68 , pp. 1309-1316
    • Marangos, P.J.1    Zomzely-Neurath, C.2    York, C.3
  • 5
    • 0000825587 scopus 로고
    • Studies on the enzyme enolase. II. Kinetic studies
    • Wold F, Ballou CE (1957) Studies on the enzyme enolase. II. Kinetic studies. J Biol Chem 227:313–328
    • (1957) J Biol Chem , vol.227 , pp. 313-328
    • Wold, F.1    Ballou, C.E.2
  • 6
    • 0021960451 scopus 로고
    • Specifi city and mechanism of action of metal ions in yeast enolase
    • Brewer JM (1985) Specifi city and mechanism of action of metal ions in yeast enolase. FEBS Lett 182:8–14
    • (1985) FEBS Lett , vol.182 , pp. 8-14
    • Brewer, J.M.1
  • 7
    • 0017373319 scopus 로고
    • Magnesium ion requirements for yeast enolase activity
    • Faller LD, Baroudy BM, Johnson AM et al (1977) Magnesium ion requirements for yeast enolase activity. Biochemistry 16:3864–3869
    • (1977) Biochemistry , vol.16 , pp. 3864-3869
    • Faller, L.D.1    Baroudy, B.M.2    Johnson, A.M.3
  • 8
    • 0014010751 scopus 로고
    • The effect of magnesium on some physical properties of yeast enolase
    • Brewer JM, Weber G (1966) The effect of magnesium on some physical properties of yeast enolase. J Biol Chem 241:2550–2557
    • (1966) J Biol Chem , vol.241 , pp. 2550-2557
    • Brewer, J.M.1    Weber, G.2
  • 9
    • 0005744975 scopus 로고
    • Calorimetric studies of the role of magnesium ions in yeast enolase catalysis
    • Faller LD, Johnson AM (1974) Calorimetric studies of the role of magnesium ions in yeast enolase catalysis. Proc Natl Acad Sci U S A 71:1083–1087
    • (1974) Proc Natl Acad Sci U S A , vol.71 , pp. 1083-1087
    • Faller, L.D.1    Johnson, A.M.2
  • 10
    • 0014604476 scopus 로고
    • Kinetic studies on the activation of yeast enolase by divalent cations
    • Hanlon DP, Westhead EW (1969) Kinetic studies on the activation of yeast enolase by divalent cations. Biochemistry 8:4255–4260
    • (1969) Biochemistry , vol.8 , pp. 4255-4260
    • Hanlon, D.P.1    Westhead, E.W.2
  • 11
    • 0015132689 scopus 로고
    • The increase of yeast enolase fl uorescence produced by substrates and competitive inhibitors in the presence of excess Mg 2+
    • Brewer JM (1971) The increase of yeast enolase fl uorescence produced by substrates and competitive inhibitors in the presence of excess Mg 2+. Biochim Biophys Acta 250:251–257
    • (1971) Biochim Biophys Acta , vol.250 , pp. 251-257
    • Brewer, J.M.1
  • 12
    • 0035838359 scopus 로고    scopus 로고
    • Role of metal ions in catalysis by enolase: An ordered kinetic mechanism for a single substrate enzyme
    • Poyner RR, Cleland WW, Reed GH (2001) Role of metal ions in catalysis by enolase: an ordered kinetic mechanism for a single substrate enzyme. Biochemistry 40:8009–8017
    • (2001) Biochemistry , vol.40 , pp. 8009-8017
    • Poyner, R.R.1    Cleland, W.W.2    Reed, G.H.3
  • 13
    • 0018191049 scopus 로고
    • Neuronal, non-neuronal and hybrid forms of enolase in brain: Structural, immunological and functional comparisons
    • Marangos PJ, Zis AP, Clark RL et al (1978) Neuronal, non-neuronal and hybrid forms of enolase in brain: structural, immunological and functional comparisons. Brain Res 150:117–133
    • (1978) Brain Res , vol.150 , pp. 117-133
    • Marangos, P.J.1    Zis, A.P.2    Clark, R.L.3
  • 14
    • 84913414512 scopus 로고
    • Granule cell neurons in developing rat and monkey cerebellum change from glial to neuronal enolase
    • Schmechel DE, Brightman MW, Marangos PJ et al (1978) Granule cell neurons in developing rat and monkey cerebellum change from glial to neuronal enolase. J Anat 4:126
    • (1978) J Anat , vol.4
    • Schmechel, D.E.1    Brightman, M.W.2    Marangos, P.J.3
  • 15
    • 0017904207 scopus 로고
    • Brain enolases as specifi c markers of neuronal and glial cells
    • Schmechel D, Marangos PJ, Zis AP et al (1978) Brain enolases as specifi c markers of neuronal and glial cells. Science 199:313–315
    • (1978) Science , vol.199 , pp. 313-315
    • Schmechel, D.1    Marangos, P.J.2    Zis, A.P.3
  • 16
    • 0023161086 scopus 로고
    • Neuron specifi c enolase, a clinically useful marker for neurons and neuroendocrine cells
    • Marangos PJ, Schmechel DE (1987) Neuron specifi c enolase, a clinically useful marker for neurons and neuroendocrine cells. Annu Rev Neurosci 10:269–295
    • (1987) Annu Rev Neurosci , vol.10 , pp. 269-295
    • Marangos, P.J.1    Schmechel, D.E.2
  • 17
    • 3843145057 scopus 로고    scopus 로고
    • Expression, purifi cation and the 1.8 angstroms resolution crystal structure of human neuron specifi c enolase
    • Chai G, Brewer JM, Lovelace LL et al (2004) Expression, purifi cation and the 1.8 angstroms resolution crystal structure of human neuron specifi c enolase. J Mol Biol 341:1015–1021
    • (2004) J Mol Biol , vol.341 , pp. 1015-1021
    • Chai, G.1    Brewer, J.M.2    Lovelace, L.L.3
  • 18
    • 0024234650 scopus 로고
    • Complete amino acid sequence of the neuronespecifi c gamma isozyme of enolase (NSE) from human brain and comparison with the non-neuronal alpha form (NNE)
    • McAleese SM, Dunbar B, Fothergill JE et al (1988) Complete amino acid sequence of the neuronespecifi c gamma isozyme of enolase (NSE) from human brain and comparison with the non-neuronal alpha form (NNE). Eur J Biochem 178:413–417
    • (1988) Eur J Biochem , vol.178 , pp. 413-417
    • McAleese, S.M.1    Dunbar, B.2    Fothergill, J.E.3
  • 19
    • 0038464170 scopus 로고
    • Molecular cloning and nucleotide sequence of a full-length cDNA for human alpha enolase
    • Giallongo A, Feo S, Moore R et al (1986) Molecular cloning and nucleotide sequence of a full-length cDNA for human alpha enolase. Proc Natl Acad Sci U S A 83:6741–6745
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 6741-6745
    • Giallongo, A.1    Feo, S.2    Moore, R.3
  • 20
    • 0025730214 scopus 로고
    • Complete structure of the human gene encoding neuron-specifi c enolase
    • Oliva D, Calì L, Feo S et al (1991) Complete structure of the human gene encoding neuron-specifi c enolase. Genomics 10:157–165
    • (1991) Genomics , vol.10 , pp. 157-165
    • Oliva, D.1    Calì, L.2    Feo, S.3
  • 21
    • 0023547091 scopus 로고
    • The structure and expression of neuron-specifi c enolase gene
    • Sakimura K, Kushiya E, Takahashi Y et al (1987) The structure and expression of neuron-specifi c enolase gene. Gene 60:103–113
    • (1987) Gene , vol.60 , pp. 103-113
    • Sakimura, K.1    Kushiya, E.2    Takahashi, Y.3
  • 22
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird AP (1986) CpG-rich islands and the function of DNA methylation. Nature 321:209–213
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 23
    • 0021955067 scopus 로고
    • Immunohistochemical localization of gammaenolase in normal human tissues other than nervous and neuroendocrine tissues
    • Haimoto H, Takahashi Y, Koshikawa T et al (1985) Immunohistochemical localization of gammaenolase in normal human tissues other than nervous and neuroendocrine tissues. Lab Invest 52:257–263
    • (1985) Lab Invest , vol.52 , pp. 257-263
    • Haimoto, H.1    Takahashi, Y.2    Koshikawa, T.3
  • 24
    • 0023916462 scopus 로고
    • Human gamma enolase: Isolation of a cDNA clone and expression in normal and tumor tissues of human origin
    • Van Obberghen E, Kamholz J, Bishop JG 3rd et al (1988) Human gamma enolase: isolation of a cDNA clone and expression in normal and tumor tissues of human origin. J Neurosci Res 19:450–456
    • (1988) J Neurosci Res , vol.19 , pp. 450-456
    • Van Obberghen, E.1    Kamholz, J.2    Bishop, J.G.3
  • 25
    • 0015997704 scopus 로고
    • The human loci for phosphopyruvate hydratase and guanylate kinase are syntenic with the PGDPGM1 linkage group in man-Chinese hamster somatic cell hybrids
    • Meera Khan P, Doppert BA, Hagemeijer A et al (1974) The human loci for phosphopyruvate hydratase and guanylate kinase are syntenic with the PGDPGM1 linkage group in man-Chinese hamster somatic cell hybrids. Cytogenet Cell Genet 13:130–131
    • (1974) Cytogenet Cell Genet , vol.13 , pp. 130-131
    • Meera Khan, P.1    Doppert, B.A.2    Hagemeijer, A.3
  • 26
    • 0018562513 scopus 로고
    • Report of the committee on the genetic constitution of chromosome 1
    • Cook PJ, Hamerton JL (1979) Report of the committee on the genetic constitution of chromosome 1 Cytogenet Cell Genet 25:9–20
    • (1979) Cytogenet Cell Genet , vol.25 , pp. 9-20
    • Cook, P.J.1    Hamerton, J.L.2
  • 27
    • 0017213865 scopus 로고
    • Assignment of human genes: Beta-glucuronidase to chromosome 7, adenylate kinase-1 to 9, a second enzyme with enolase activity to 12, and mitochondrial IDH to 15
    • Grzeschik KH (1976) Assignment of human genes: beta-glucuronidase to chromosome 7, adenylate kinase-1 to 9, a second enzyme with enolase activity to 12, and mitochondrial IDH to 15. Birth Defects Orig Artic Ser 12:142–148
    • (1976) Birth Defects Orig Artic Ser , vol.12 , pp. 142-148
    • Grzeschik, K.H.1
  • 28
    • 0020094956 scopus 로고
    • Regional mapping of the gene coding for enolase-2 on human chromosome 12
    • Law ML, Kao FT (1982) Regional mapping of the gene coding for enolase-2 on human chromosome 12. J Cell Sci 53:245–254
    • (1982) J Cell Sci , vol.53 , pp. 245-254
    • Law, M.L.1    Kao, F.T.2
  • 29
    • 0025258204 scopus 로고
    • Localisation of neurone-specifi c enolase (ENO2) to 12p13
    • Craig SP, Day IN, Thompson RJ et al (1990) Localisation of neurone-specifi c enolase (ENO2) to 12p13. Cytogenet Cell Genet 54:71–73
    • (1990) Cytogenet Cell Genet , vol.54 , pp. 71-73
    • Craig, S.P.1    Day, I.N.2    Thompson, R.J.3
  • 30
    • 0025372882 scopus 로고
    • The gene for the muscle-specifi c enolase is on the short arm of human chromosome 17
    • Feo S, Oliva D, Barbieri G et al (1990) The gene for the muscle-specifi c enolase is on the short arm of human chromosome 17. Genomics 6:192–194
    • (1990) Genomics , vol.6 , pp. 192-194
    • Feo, S.1    Oliva, D.2    Barbieri, G.3
  • 31
    • 84865134914 scopus 로고    scopus 로고
    • Passenger deletions generate therapeutic vulnerabilities in cancer
    • Muller FL, Colla S, Aquilanti E et al (2012) Passenger deletions generate therapeutic vulnerabilities in cancer. Nature 488:337–342
    • (2012) Nature , vol.488 , pp. 337-342
    • Muller, F.L.1    Colla, S.2    Aquilanti, E.3
  • 32
    • 0016272164 scopus 로고
    • Enolase isoenzymes in rat tissues. Electrophoretic, chromatographic, immunological and kinetic properties
    • Rider CC, Taylor CB (1974) Enolase isoenzymes in rat tissues. Electrophoretic, chromatographic, immunological and kinetic properties. Biochim Biophys Acta 365:285–300
    • (1974) Biochim Biophys Acta , vol.365 , pp. 285-300
    • Rider, C.C.1    Taylor, C.B.2
  • 33
    • 0019223862 scopus 로고
    • Neurons switch from non-neuronal enolase to neuron-specifi c enolase during differentiation
    • Schmechel DE, Brightman MW, Marangos PJ (1980) Neurons switch from non-neuronal enolase to neuron-specifi c enolase during differentiation. Brain Res 190:195–214
    • (1980) Brain Res , vol.190 , pp. 195-214
    • Schmechel, D.E.1    Brightman, M.W.2    Marangos, P.J.3
  • 34
    • 0022320018 scopus 로고
    • Switching in levels of translatable mRNAs for enolase isozymes during development of chicken skeletal muscle
    • Tanaka M, Sugisaki K, Nakashima K (1985) Switching in levels of translatable mRNAs for enolase isozymes during development of chicken skeletal muscle. Biochem Biophys Res Commun 133:868–872
    • (1985) Biochem Biophys Res Commun , vol.133 , pp. 868-872
    • Tanaka, M.1    Sugisaki, K.2    Nakashima, K.3
  • 35
    • 0018888696 scopus 로고
    • Developmental profi le of neuron-specifi c (NSE) and non-neuronal (NNE) enolase
    • Marangos PJ, Schmechel DE, Parma AM et al (1980) Developmental profi le of neuron-specifi c (NSE) and non-neuronal (NNE) enolase. Brain Res 190:185–193
    • (1980) Brain Res , vol.190 , pp. 185-193
    • Marangos, P.J.1    Schmechel, D.E.2    Parma, A.M.3
  • 36
    • 0021323145 scopus 로고
    • Human neuron-specifi c enolase: Genetic and developmental studies
    • Chen SH, Omenn GS (1984) Human neuron-specifi c enolase: genetic and developmental studies. J Neurogenet 1:159–164
    • (1984) J Neurogenet , vol.1 , pp. 159-164
    • Chen, S.H.1    Omenn, G.S.2
  • 37
    • 0030739137 scopus 로고    scopus 로고
    • Chromogranin A as serum marker for neuroendocrine neoplasia: Comparison with neuronspecifi c enolase and the alpha-subunit of glycoprotein hormones
    • Nobels FR, Kwekkeboom DJ, Coopmans W et al (1997) Chromogranin A as serum marker for neuroendocrine neoplasia: comparison with neuronspecifi c enolase and the alpha-subunit of glycoprotein hormones. J Clin Endocrinol Metab 82:2622–2628
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2622-2628
    • Nobels, F.R.1    Kwekkeboom, D.J.2    Coopmans, W.3
  • 38
    • 0033843657 scopus 로고    scopus 로고
    • Tumor markers in neuroendocrine tumors
    • Eriksson B, Oberg K, Stridsberg M (2000) Tumor markers in neuroendocrine tumors. Digestion 62(Suppl 1):33–38
    • (2000) Digestion , vol.62 , pp. 33-38
    • Eriksson, B.1    Oberg, K.2    Stridsberg, M.3
  • 39
    • 7344256182 scopus 로고    scopus 로고
    • Neuron-specifi c enolase and chromogranin A as markers of neuroendocrine tumours
    • Baudin E, Gigliotti A, Ducreux M et al (1998) Neuron-specifi c enolase and chromogranin A as markers of neuroendocrine tumours. Br J Cancer 78:1102–1107
    • (1998) Br J Cancer , vol.78 , pp. 1102-1107
    • Baudin, E.1    Gigliotti, A.2    Ducreux, M.3
  • 40
    • 0033197983 scopus 로고    scopus 로고
    • Chromogranin A, neuron specifi c enolase, carcinoembryonic antigen, and hydroxyindole acetic acid evaluation in patients with neuroendocrine tumors
    • Bajetta E, Ferrari L, Martinetti A et al (1999) Chromogranin A, neuron specifi c enolase, carcinoembryonic antigen, and hydroxyindole acetic acid evaluation in patients with neuroendocrine tumors. Cancer 86:858–865
    • (1999) Cancer , vol.86 , pp. 858-865
    • Bajetta, E.1    Ferrari, L.2    Martinetti, A.3
  • 41
    • 0023821646 scopus 로고
    • Neuron-specifi c enolase: How useful as a cancer marker?
    • Carney DN, Teeling M (1988) Neuron-specifi c enolase: how useful as a cancer marker? Eur J Cancer Clin Oncol 24:825–828
    • (1988) Eur J Cancer Clin Oncol , vol.24 , pp. 825-828
    • Carney, D.N.1    Teeling, M.2
  • 43
    • 0018778612 scopus 로고
    • Measurement of neuron-specifi c (NSE) and nonneuronal (NNE) isoenzymes of enolase in rat, monkey and human nervous tissue
    • Marangos PJ, Schmechel D, Parma AM et al (1979) Measurement of neuron-specifi c (NSE) and nonneuronal (NNE) isoenzymes of enolase in rat, monkey and human nervous tissue. J Neurochem 33:319–329
    • (1979) J Neurochem , vol.33 , pp. 319-329
    • Marangos, P.J.1    Schmechel, D.2    Parma, A.M.3
  • 44
    • 0019434199 scopus 로고
    • A more sensitive radioimmunoassay for neuronspecifi c enolase suitable for cerebrospinal fl uid determinations
    • Parma AM, Marangos PJ, Goodwin FK (1981) A more sensitive radioimmunoassay for neuronspecifi c enolase suitable for cerebrospinal fl uid determinations. J Neurochem 36:1093–1096
    • (1981) J Neurochem , vol.36 , pp. 1093-1096
    • Parma, A.M.1    Marangos, P.J.2    Goodwin, F.K.3
  • 45
    • 0021019875 scopus 로고
    • A bioluminescent assay for enolase (EC 4.2.1.11) activity in human serum and cerebrospinal fl uid
    • Wevers RA, Jacobs AA, Hommes OR (1983) A bioluminescent assay for enolase (EC 4.2.1.11) activity in human serum and cerebrospinal fl uid. Clin Chim Acta 135:159–168
    • (1983) Clin Chim Acta , vol.135 , pp. 159-168
    • Wevers, R.A.1    Jacobs, A.A.2    Hommes, O.R.3
  • 46
    • 0021396719 scopus 로고
    • Brainspecifi c proteins: Solid-phase immunobioluminescence assay for neuron-specifi c enolase in human plasma
    • Gerbitz KD, Summer J, Thallemer J (1984) Brainspecifi c proteins: solid-phase immunobioluminescence assay for neuron-specifi c enolase in human plasma. Clin Chem 30:382–386
    • (1984) Clin Chem , vol.30 , pp. 382-386
    • Gerbitz, K.D.1    Summer, J.2    Thallemer, J.3
  • 47
    • 0021706061 scopus 로고
    • Practicable enzyme immunoassay for neuron- specifi c enolase in human serum
    • Kimura S, Uchikawa H, Yamamoto R et al (1984) Practicable enzyme immunoassay for neuron- specifi c enolase in human serum. J Appl Biochem 6:319–324
    • (1984) J Appl Biochem , vol.6 , pp. 319-324
    • Kimura, S.1    Uchikawa, H.2    Yamamoto, R.3
  • 48
    • 0023009548 scopus 로고
    • Two-site column enzyme immunoassay for neuronspecifi c enolase (NSE) in human serum using monoclonal antibodies
    • Kimura S, Uchikawa H, Yamamoto R et al (1986) Two-site column enzyme immunoassay for neuronspecifi c enolase (NSE) in human serum using monoclonal antibodies. J Immunol Methods 94:51–55
    • (1986) J Immunol Methods , vol.94 , pp. 51-55
    • Kimura, S.1    Uchikawa, H.2    Yamamoto, R.3
  • 49
    • 0022972538 scopus 로고
    • Determination of serum neuron-specifi c enolase by differential immunocapture
    • Viallard JL, Murthy MR, Bétail G et al (1986) Determination of serum neuron-specifi c enolase by differential immunocapture. Clin Chim Acta 161:1–10
    • (1986) Clin Chim Acta , vol.161 , pp. 1-10
    • Viallard, J.L.1    Murthy, M.R.2    Bétail, G.3
  • 50
    • 0022870412 scopus 로고
    • Rapid electrophoretic determination of neuronspecifi c enolase isoenzymes in serum
    • Viallard JL, Ven Murthy MR, Dastugue B (1986) Rapid electrophoretic determination of neuronspecifi c enolase isoenzymes in serum. Clin Chem 32:593–597
    • (1986) Clin Chem , vol.32 , pp. 593-597
    • Viallard, J.L.1    Ven Murthy, M.R.2    Dastugue, B.3
  • 51
    • 0023134333 scopus 로고
    • Neuron-specifi c enolase. Assessment by ELISA in patients with small cell carcinoma of the lung
    • Anastasiades KD, Mullins RE, Conn RB (1987) Neuron-specifi c enolase. Assessment by ELISA in patients with small cell carcinoma of the lung. Am J Clin Pathol 87:245–249
    • (1987) Am J Clin Pathol , vol.87 , pp. 245-249
    • Anastasiades, K.D.1    Mullins, R.E.2    Conn, R.B.3
  • 52
    • 0024447497 scopus 로고
    • Immunoradiometric assay for alpha gamma- and gamma gamma-enolase (Neuron- specifi c enolase), with use of monoclonal antibodies and magnetizable polymer particles
    • Paus E, Nustad K (1989) Immunoradiometric assay for alpha gamma- and gamma gamma-enolase (neuron- specifi c enolase), with use of monoclonal antibodies and magnetizable polymer particles. Clin Chem 35:2034–2038
    • (1989) Clin Chem , vol.35 , pp. 2034-2038
    • Paus, E.1    Nustad, K.2
  • 53
    • 0026780232 scopus 로고
    • Monoclonal immunoradiometric assay and polyclonal radioimmunoassay compared for measuring neuron-specifi c enolase in patients with lung cancer
    • Body JJ, Paesmans M, Sculier JP et al (1992) Monoclonal immunoradiometric assay and polyclonal radioimmunoassay compared for measuring neuron-specifi c enolase in patients with lung cancer. Clin Chem 38:748–751
    • (1992) Clin Chem , vol.38 , pp. 748-751
    • Body, J.J.1    Paesmans, M.2    Sculier, J.P.3
  • 54
    • 0029836270 scopus 로고    scopus 로고
    • Methodological and clinical evaluation of two automated enzymatic immunoassays as compared with a radioimmunoassay for neuron-specifi c enolase
    • Schmitt UM, Stieber P, Hasholzner U et al (1996) Methodological and clinical evaluation of two automated enzymatic immunoassays as compared with a radioimmunoassay for neuron-specifi c enolase. Eur J Clin Chem Clin Biochem 34:679–682
    • (1996) Eur J Clin Chem Clin Biochem , vol.34 , pp. 679-682
    • Schmitt, U.M.1    Stieber, P.2    Hasholzner, U.3
  • 55
    • 0031786615 scopus 로고    scopus 로고
    • Analytical performance of the new single step COBAS Core NSE EIA II and its diagnostic utility in comparison with the established COBAS Core NSE EIA
    • Ebert W, Muley T (1998) Analytical performance of the new single step COBAS Core NSE EIA II and its diagnostic utility in comparison with the established COBAS Core NSE EIA. Clin Lab 44:871–879
    • (1998) Clin Lab , vol.44 , pp. 871-879
    • Ebert, W.1    Muley, T.2
  • 56
    • 0037215049 scopus 로고    scopus 로고
    • Technical performance and diagnostic utility of the new Elecsys neuron-specifi c enolase enzyme immunoassay
    • Muley T, Ebert W, Stieber P et al (2003) Technical performance and diagnostic utility of the new Elecsys neuron-specifi c enolase enzyme immunoassay. Clin Chem Lab Med 41:95–103
    • (2003) Clin Chem Lab Med , vol.41 , pp. 95-103
    • Muley, T.1    Ebert, W.2    Stieber, P.3
  • 57
    • 84862783147 scopus 로고    scopus 로고
    • Chemiluminescence enzyme immunoassay using magnetic nanoparticles for detection of neuron specifi c enolase in human serum
    • Fu X, Meng M, Zhang Y et al (2012) Chemiluminescence enzyme immunoassay using magnetic nanoparticles for detection of neuron specifi c enolase in human serum. Anal Chim Acta 722:114–118
    • (2012) Anal Chim Acta , vol.722 , pp. 114-118
    • Fu, X.1    Meng, M.2    Zhang, Y.3
  • 58
    • 84877900593 scopus 로고    scopus 로고
    • Immunocapture and LC-MS/MS for selective quantifi cation and differentiation of the isozymes of the biomarker neuron-specifi c enolase in serum
    • Torsetnes SB, Løvbak SG, Claus C et al (2013) Immunocapture and LC-MS/MS for selective quantifi cation and differentiation of the isozymes of the biomarker neuron-specifi c enolase in serum. J Chromatogr B Analyt Technol Biomed Life Sci 929:125–132
    • (2013) J Chromatogr B Analyt Technol Biomed Life Sci , vol.929 , pp. 125-132
    • Torsetnes, S.B.1    Løvbak, S.G.2    Claus, C.3
  • 59
    • 84891651697 scopus 로고    scopus 로고
    • Guanine-decorated graphene nanostructures for sensitive monitoring of neuronspecifi c enolase based on an enzyme-free electrocatalytic reaction
    • Li GZ, Tian F (2013) Guanine-decorated graphene nanostructures for sensitive monitoring of neuronspecifi c enolase based on an enzyme-free electrocatalytic reaction. Anal Sci 29:1195–1201
    • (2013) Anal Sci , vol.29 , pp. 1195-1201
    • Li, G.Z.1    Tian, F.2
  • 60
    • 0025072263 scopus 로고
    • New solid-phase enzyme immunoassay of neuronspecifi c enolase in serum: Effect of storage temperature, lipemia, icterus, and hemolysis
    • Mercer DW, Virji MA, Barry GE, Piper ML (1990) New solid-phase enzyme immunoassay of neuronspecifi c enolase in serum: effect of storage temperature, lipemia, icterus, and hemolysis. Clin Chem 36:1519
    • (1990) Clin Chem , vol.36
    • Mercer, D.W.1    Virji, M.A.2    Barry, G.E.3    Piper, M.L.4
  • 62
    • 27744483523 scopus 로고    scopus 로고
    • Effects of hemolysis and storage condition on neuron- specifi c enolase (NSE) in cerebrospinal fl uid and serum: Implications in clinical practice
    • Ramont L, Thoannes H, Volondat A et al (2005) Effects of hemolysis and storage condition on neuron- specifi c enolase (NSE) in cerebrospinal fl uid and serum: implications in clinical practice. Clin Chem Lab Med 43:1215–1217
    • (2005) Clin Chem Lab Med , vol.43 , pp. 1215-1217
    • Ramont, L.1    Thoannes, H.2    Volondat, A.3
  • 63
    • 77950326721 scopus 로고    scopus 로고
    • Importance of hemolysis on neuron-specifi c enolase measurement
    • Planche V, Brochet C, Bakkouch A et al (2010) Importance of hemolysis on neuron-specifi c enolase measurement. Ann Biol Clin 68:239–242
    • (2010) Ann Biol Clin , vol.68 , pp. 239-242
    • Planche, V.1    Brochet, C.2    Bakkouch, A.3
  • 64
    • 84871813127 scopus 로고    scopus 로고
    • Biological variation of neuroendocrine tumor markers chromogranin A and neuron-specifi c enolase
    • Braga F, Ferraro S, Mozzi R et al (2013) Biological variation of neuroendocrine tumor markers chromogranin A and neuron-specifi c enolase. Clin Biochem 46:148–151
    • (2013) Clin Biochem , vol.46 , pp. 148-151
    • Braga, F.1    Ferraro, S.2    Mozzi, R.3
  • 65
    • 84880619025 scopus 로고    scopus 로고
    • Re: Biological variation of neuroendocrine tumor markers chromogranin A and neuron-specifi c enolase
    • Dittadi R, Gion M (2013) Re: biological variation of neuroendocrine tumor markers chromogranin A and neuron-specifi c enolase. Clin Biochem 46:1145
    • (2013) Clin Biochem , vol.46
    • Dittadi, R.1    Gion, M.2
  • 66
    • 0020282907 scopus 로고
    • Use of neuron specifi c enolase as a serum marker for neuroendocrine neoplasms
    • Prinz RA, Marangos PJ (1982) Use of neuron specifi c enolase as a serum marker for neuroendocrine neoplasms. Surgery 97:887–889
    • (1982) Surgery , vol.97 , pp. 887-889
    • Prinz, R.A.1    Marangos, P.J.2
  • 67
    • 43149098539 scopus 로고    scopus 로고
    • The biological characterization of neuroendocrine tumors: The role of neuroendocrine markers
    • Ferolla P, Faggiano A, Mansueto G et al (2008) The biological characterization of neuroendocrine tumors: the role of neuroendocrine markers. J Endocrinol Invest 31:277–286
    • (2008) J Endocrinol Invest , vol.31 , pp. 277-286
    • Ferolla, P.1    Faggiano, A.2    Mansueto, G.3
  • 68
    • 0014510423 scopus 로고
    • The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept
    • Pearse AG (1969) The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. J Histochem Cytochem 17:303–313
    • (1969) J Histochem Cytochem , vol.17 , pp. 303-313
    • Pearse, A.G.1
  • 69
    • 0031947554 scopus 로고    scopus 로고
    • Large cell neuroendocrine carcinoma of the lung: A histologic and immunohistochemical study of 22 cases
    • Jiang SX, Kameya T, Shoji M et al (1998) Large cell neuroendocrine carcinoma of the lung: a histologic and immunohistochemical study of 22 cases. Am J Surg Pathol 22:526–537
    • (1998) Am J Surg Pathol , vol.22 , pp. 526-537
    • Jiang, S.X.1    Kameya, T.2    Shoji, M.3
  • 70
    • 0032944026 scopus 로고    scopus 로고
    • Screening for multiple endocrine neoplasia type 1 and hormonal production in apparently sporadic neuroendocrine tumors
    • Baudin E, Bidart JM, Rougier P et al (1999) Screening for multiple endocrine neoplasia type 1 and hormonal production in apparently sporadic neuroendocrine tumors. J Clin Endocrinol Metab 84:69–75
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 69-75
    • Baudin, E.1    Bidart, J.M.2    Rougier, P.3
  • 71
    • 0020070666 scopus 로고
    • The World Health Organization histological typing of lung tumours. Second edition
    • World Health Organization (1982) The World Health Organization histological typing of lung tumours. Second edition. Am J Clin Pathol 77:123–136
    • (1982) Am J Clin Pathol , vol.77 , pp. 123-136
  • 72
    • 0033728154 scopus 로고    scopus 로고
    • Comparative prognostic value of lactate dehydrogenase and neuron-specifi c enolase in small-cell lung cancer patients treated with platinum-based chemotherapy
    • Quoix E, Purohit A, Faller-Beau M et al (2000) Comparative prognostic value of lactate dehydrogenase and neuron-specifi c enolase in small-cell lung cancer patients treated with platinum-based chemotherapy. Lung Cancer 30:127–134
    • (2000) Lung Cancer , vol.30 , pp. 127-134
    • Quoix, E.1    Purohit, A.2    Faller-Beau, M.3
  • 73
    • 0022398080 scopus 로고
    • Evaluation of a radioimmunoassay for neuron specifi c enolase in small cell lung cancer
    • Cooper EH, Splinter TA, Brown DA et al (1985) Evaluation of a radioimmunoassay for neuron specifi c enolase in small cell lung cancer. Br J Cancer 52:333–338
    • (1985) Br J Cancer , vol.52 , pp. 333-338
    • Cooper, E.H.1    Splinter, T.A.2    Brown, D.A.3
  • 74
    • 0025248455 scopus 로고
    • Neurone specifi c enolase (NSE) in small cell lung cancer: A tumour marker of prognostic signifi cance?
    • Harding M, McAllister J, Hulks G et al (1990) Neurone specifi c enolase (NSE) in small cell lung cancer: a tumour marker of prognostic signifi cance? Br J Cancer 61:605–607
    • (1990) Br J Cancer , vol.61 , pp. 605-607
    • Harding, M.1    McAllister, J.2    Hulks, G.3
  • 75
    • 0025025642 scopus 로고
    • Clinical and serologic markers of stage and prognosis in small cell lung cancer. A multivariate analysis
    • Gronowitz JS, Bergström R, Nôu E et al (1990) Clinical and serologic markers of stage and prognosis in small cell lung cancer. A multivariate analysis. Cancer 66:722–732
    • (1990) Cancer , vol.66 , pp. 722-732
    • Gronowitz, J.S.1    Bergström, R.2    Nôu, E.3
  • 76
    • 0025615994 scopus 로고
    • Clinical value of neuron specifi c enolase and tissue polipeptidic antigen for the management of patients with lung cancer
    • Spinazzi A, Soresi E, Borghini U et al (1990) Clinical value of neuron specifi c enolase and tissue polipeptidic antigen for the management of patients with lung cancer. J Nucl Med Allied Sci 34:141–145
    • (1990) J Nucl Med Allied Sci , vol.34 , pp. 141-145
    • Spinazzi, A.1    Soresi, E.2    Borghini, U.3
  • 77
    • 0029052646 scopus 로고
    • Evaluation of the serum markers CEA, NSE, TPS and CYFRA 21.1 in lung cancer
    • Giovanella L, Ceriani L, Bandera M et al (1995) Evaluation of the serum markers CEA, NSE, TPS and CYFRA 21.1 in lung cancer. Int J Biol Markers 10:156–160
    • (1995) Int J Biol Markers , vol.10 , pp. 156-160
    • Giovanella, L.1    Ceriani, L.2    Bandera, M.3
  • 78
    • 0030917483 scopus 로고    scopus 로고
    • Immunoassay of neuron-specifi c enolase (NSE) and serum fragments of cytokeratin 19 (CYFRA 21.1) as tumor markers in small cell lung cancer: Clinical evaluation and biological hypothesis
    • Giovanella L, Piantanida R, Ceriani L et al (1997) Immunoassay of neuron-specifi c enolase (NSE) and serum fragments of cytokeratin 19 (CYFRA 21.1) as tumor markers in small cell lung cancer: clinical evaluation and biological hypothesis. Int J Biol Markers 12:22–26
    • (1997) Int J Biol Markers , vol.12 , pp. 22-26
    • Giovanella, L.1    Piantanida, R.2    Ceriani, L.3
  • 79
    • 0029166765 scopus 로고
    • Discriminant analysis on small cell lung cancer and non-small cell lung cancer by means of NSE and CYFRA-21.1
    • Paone G, De Angelis G, Munno R et al (1995) Discriminant analysis on small cell lung cancer and non-small cell lung cancer by means of NSE and CYFRA-21.1. Eur Respir J 8:1136–1140
    • (1995) Eur Respir J , vol.8 , pp. 1136-1140
    • Paone, G.1    De Angelis, G.2    Munno, R.3
  • 80
    • 0031031604 scopus 로고    scopus 로고
    • Validation of an algorithm able to differentiate small-cell lung cancer (SCLC) from non-small-cell lung cancer (NSCLC) patients by means of a tumour marker panel: Analysis of the errors
    • Paone G, De Angelis G, Portalone L et al (1997) Validation of an algorithm able to differentiate small-cell lung cancer (SCLC) from non-small-cell lung cancer (NSCLC) patients by means of a tumour marker panel: analysis of the errors. Br J Cancer 75:448–450
    • (1997) Br J Cancer , vol.75 , pp. 448-450
    • Paone, G.1    De Angelis, G.2    Portalone, L.3
  • 81
    • 0030016693 scopus 로고    scopus 로고
    • Serum neuron-specifi c enolase (S-NSE) and the prognosis in small-cell lung cancer (SCLC): A combined multivariable analysis on data from nine centres
    • Jørgensen LG, Osterlind K, Genollá J et al (1996) Serum neuron-specifi c enolase (S-NSE) and the prognosis in small-cell lung cancer (SCLC): a combined multivariable analysis on data from nine centres. Br J Cancer 74:463–467
    • (1996) Br J Cancer , vol.74 , pp. 463-467
    • Jørgensen, L.G.1    Osterlind, K.2    Genollá, J.3
  • 82
    • 0021969980 scopus 로고
    • Neurone specifi c enolase: A useful diagnostic serum marker for small cell carcinoma of the lung
    • Esscher T, Steinholtz L, Bergh J et al (1985) Neurone specifi c enolase: a useful diagnostic serum marker for small cell carcinoma of the lung. Thorax 40:85–90
    • (1985) Thorax , vol.40 , pp. 85-90
    • Esscher, T.1    Steinholtz, L.2    Bergh, J.3
  • 83
    • 9344226203 scopus 로고    scopus 로고
    • Progastrin- releasing peptide (31–98) as a tumour marker of small-cell lung cancer: Comparative evaluation with neuron-specifi c enolase
    • Takada M, Kusunoki Y, Masuda N et al (1996) Progastrin- releasing peptide (31–98) as a tumour marker of small-cell lung cancer: comparative evaluation with neuron-specifi c enolase. Br J Cancer 73:1227–1232
    • (1996) Br J Cancer , vol.73 , pp. 1227-1232
    • Takada, M.1    Kusunoki, Y.2    Masuda, N.3
  • 84
    • 0035077736 scopus 로고    scopus 로고
    • Immunoradiometric assay of chromogranin A in the diagnosis of small cell lung cancer: Comparative evaluation with neuron-specifi c enolase
    • Giovanella L, Ceriani L, Bandera M et al (2001) Immunoradiometric assay of chromogranin A in the diagnosis of small cell lung cancer: comparative evaluation with neuron-specifi c enolase. Int J Biol Markers 16:50–55
    • (2001) Int J Biol Markers , vol.16 , pp. 50-55
    • Giovanella, L.1    Ceriani, L.2    Bandera, M.3
  • 85
    • 84890965213 scopus 로고    scopus 로고
    • The prognostic signifi cance of the circulating neuroendocrine markers chromogranin A, pro-gastrinreleasing peptide, and neuron-specifi c enolase in patients with small-cell lung cancer
    • Petrović M, Bukumirić Z, Zdravković V et al (2014) The prognostic signifi cance of the circulating neuroendocrine markers chromogranin A, pro-gastrinreleasing peptide, and neuron-specifi c enolase in patients with small-cell lung cancer. Med Oncol 31:823
    • (2014) Med Oncol , vol.31
    • Petrović, M.1    Bukumirić, Z.2    Zdravković, V.3
  • 86
    • 0021972838 scopus 로고
    • Differential expression of intermediate fi lament proteins distinguishes classic from variant small-cell lung cancer cell lines
    • Broers JL, Carney DN, de Ley L et al (1985) Differential expression of intermediate fi lament proteins distinguishes classic from variant small-cell lung cancer cell lines. Proc Natl Acad Sci U S A 82:4409–4413
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 4409-4413
    • Broers, J.L.1    Carney, D.N.2    De Ley, L.3
  • 87
    • 0036841417 scopus 로고    scopus 로고
    • Carcinoembryonic antigen, squamous cell carcinoma antigen, CYFRA 21-1, and neuron-specifi c enolase in squamous cell lung cancer patients
    • Kulpa J, Wójcik E, Reinfuss M et al (2002) Carcinoembryonic antigen, squamous cell carcinoma antigen, CYFRA 21-1, and neuron-specifi c enolase in squamous cell lung cancer patients. Clin Chem 48:1931–1937
    • (2002) Clin Chem , vol.48 , pp. 1931-1937
    • Kulpa, J.1    Wójcik, E.2    Reinfuss, M.3
  • 88
    • 0035145078 scopus 로고    scopus 로고
    • Cyfra 21-1, neuron specifi c enolase and prognosis of nonsmall cell lung cancer: Prospective study in 621 patients
    • Pujol JL, Boher JM, Grenier J et al (2001) Cyfra 21-1, neuron specifi c enolase and prognosis of nonsmall cell lung cancer: prospective study in 621 patients. Lung Cancer 31:221–231
    • (2001) Lung Cancer , vol.31 , pp. 221-231
    • Pujol, J.L.1    Boher, J.M.2    Grenier, J.3
  • 89
    • 40549120599 scopus 로고    scopus 로고
    • Predictive and prognostic signifi cance of neuronspecifi c enolase (NSE) in non-small cell lung cancer
    • Tiseo M, Ardizzoni A, Cafferata MA et al (2008) Predictive and prognostic signifi cance of neuronspecifi c enolase (NSE) in non-small cell lung cancer. Anticancer Res 28:507–513
    • (2008) Anticancer Res , vol.28 , pp. 507-513
    • Tiseo, M.1    Ardizzoni, A.2    Cafferata, M.A.3
  • 90
    • 0028438017 scopus 로고
    • Serum neuron specifi c enolase level as a prognostic factor in non-small cell lung cancer
    • Andoh M, Gemma A, Takenaka K et al (1994) Serum neuron specifi c enolase level as a prognostic factor in non-small cell lung cancer. Intern Med 33:271–276
    • (1994) Intern Med , vol.33 , pp. 271-276
    • Andoh, M.1    Gemma, A.2    Takenaka, K.3
  • 91
    • 0027477568 scopus 로고
    • Value of serum neuron-specifi c enolase in nonsmall cell lung cancer
    • Diez M, Torres A, Ortega L et al (1993) Value of serum neuron-specifi c enolase in nonsmall cell lung cancer. Oncology 50:127–131
    • (1993) Oncology , vol.50 , pp. 127-131
    • Diez, M.1    Torres, A.2    Ortega, L.3
  • 92
    • 84898899950 scopus 로고    scopus 로고
    • Neuron specifi c enolase and prognosis of non-small cell lung cancer: A systematic review and meta-analysis
    • Yan HJ, Tan Y, Gu W (2014) Neuron specifi c enolase and prognosis of non-small cell lung cancer: a systematic review and meta-analysis. J BUON 19:153–156
    • (2014) J BUON , vol.19 , pp. 153-156
    • Yan, H.J.1    Tan, Y.2    Gu, W.3
  • 93
    • 73949088959 scopus 로고    scopus 로고
    • Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: A phase II trial
    • Yao JC, Lombard-Bohas C, Baudin E et al (2010) Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: a phase II trial. J Clin Oncol 28:69–76
    • (2010) J Clin Oncol , vol.28 , pp. 69-76
    • Yao, J.C.1    Lombard-Bohas, C.2    Baudin, E.3
  • 94
    • 0034105523 scopus 로고    scopus 로고
    • Clinical prognostic factors in 1277 patients with neuroblastoma: Results of The European Neuroblastoma Study Group ‘Survey’ 1982–1992
    • Cotterill SJ, Pearson AD, Pritchard J et al (2000) Clinical prognostic factors in 1277 patients with neuroblastoma: results of The European Neuroblastoma Study Group ‘Survey’ 1982–1992. Eur J Cancer 36:901–908
    • (2000) Eur J Cancer , vol.36 , pp. 901-908
    • Cotterill, S.J.1    Pearson, A.D.2    Pritchard, J.3
  • 95
    • 0020552479 scopus 로고
    • Raised neuron-specifi c enolase in serum of children with metastatic neuroblastoma. A report from the Children’s Cancer Study Group
    • Zeltzer PM, Marangos PJ, Parma AM et al (1983) Raised neuron-specifi c enolase in serum of children with metastatic neuroblastoma. A report from the Children’s Cancer Study Group. Lancet 2:361–363
    • (1983) Lancet , vol.2 , pp. 361-363
    • Zeltzer, P.M.1    Marangos, P.J.2    Parma, A.M.3
  • 96
    • 0022622713 scopus 로고
    • Serum neuron-specifi c enolase in children with neuroblastoma. Relationship to stage and disease course
    • Zeltzer PM, Marangos PJ, Evans AE et al (1986) Serum neuron-specifi c enolase in children with neuroblastoma. Relationship to stage and disease course. Cancer 57:1230–1234
    • (1986) Cancer , vol.57 , pp. 1230-1234
    • Zeltzer, P.M.1    Marangos, P.J.2    Evans, A.E.3
  • 97
    • 1642453771 scopus 로고    scopus 로고
    • A systematic review of molecular and biological tumor markers in neuroblastoma
    • Riley RD, Heney D, Jones DR et al (2004) A systematic review of molecular and biological tumor markers in neuroblastoma. Clin Cancer Res 10:4–12
    • (2004) Clin Cancer Res , vol.10 , pp. 4-12
    • Riley, R.D.1    Heney, D.2    Jones, D.R.3
  • 98
    • 0031859814 scopus 로고    scopus 로고
    • Neuronspecifi c enolase: Reference values in cord blood
    • Kintzel K, Sonntag J, Strauss E et al (1998) Neuronspecifi c enolase: reference values in cord blood. Clin Chem Lab Med 36:245–247
    • (1998) Clin Chem Lab Med , vol.36 , pp. 245-247
    • Kintzel, K.1    Sonntag, J.2    Strauss, E.3
  • 99
    • 0030711721 scopus 로고    scopus 로고
    • S-100 protein and neuron-specifi c enolase concentrations in blood as indicators of infarction volume and prognosis in acute ischemic stroke
    • Missler U, Wiesmann M, Friedrich C et al (1997) S-100 protein and neuron-specifi c enolase concentrations in blood as indicators of infarction volume and prognosis in acute ischemic stroke. Stroke 28:1956–1960
    • (1997) Stroke , vol.28 , pp. 1956-1960
    • Missler, U.1    Wiesmann, M.2    Friedrich, C.3
  • 100
    • 0037227327 scopus 로고    scopus 로고
    • Prediction of early clinical severity and extent of neuronal damage in anterior-circulation infarction using the initial serum neuron-specifi c enolase level
    • Oh SH, Lee JG, Na SJ et al (2003) Prediction of early clinical severity and extent of neuronal damage in anterior-circulation infarction using the initial serum neuron-specifi c enolase level. Arch Neurol 60:37–41
    • (2003) Arch Neurol , vol.60 , pp. 37-41
    • Oh, S.H.1    Lee, J.G.2    Na, S.J.3
  • 101
    • 33746929545 scopus 로고    scopus 로고
    • Neuron-specifi c enolase and tau protein as neurobiochemical markers of neuronal damage are related to early clinical course and long-term outcome in acute ischemic stroke
    • Wunderlich MT, Lins H, Skalej M et al (2006) Neuron-specifi c enolase and tau protein as neurobiochemical markers of neuronal damage are related to early clinical course and long-term outcome in acute ischemic stroke. Clin Neurol Neurosurg 108:558–563
    • (2006) Clin Neurol Neurosurg , vol.108 , pp. 558-563
    • Wunderlich, M.T.1    Lins, H.2    Skalej, M.3
  • 102
    • 77649218035 scopus 로고    scopus 로고
    • Neurobiochemical markers of brain damage in cerebrospinal fl uid of acute ischemic stroke patients
    • Brouns R, De Vil B, Cras P et al (2010) Neurobiochemical markers of brain damage in cerebrospinal fl uid of acute ischemic stroke patients. Clin Chem 56:451–458
    • (2010) Clin Chem , vol.56 , pp. 451-458
    • Brouns, R.1    De Vil, B.2    Cras, P.3
  • 103
    • 84868300132 scopus 로고    scopus 로고
    • Short-term prognostic value of serum neuron specifi c enolase and S100B in acute stroke patients
    • González-García S, González-Quevedo A, Fernández-Concepción O et al (2012) Short-term prognostic value of serum neuron specifi c enolase and S100B in acute stroke patients. Clin Biochem 45:1302–1307
    • (2012) Clin Biochem , vol.45 , pp. 1302-1307
    • González-García, S.1    González-Quevedo, A.2    Fernández-Concepción, O.3
  • 104
    • 84887594012 scopus 로고    scopus 로고
    • Correlation between serum neuron specifi c enolase and functional neurological outcome in patients of acute ischemic stroke
    • Zaheer S, Beg M, Rizvi I et al (2013) Correlation between serum neuron specifi c enolase and functional neurological outcome in patients of acute ischemic stroke. Ann Indian Acad Neurol 16:504–508
    • (2013) Ann Indian Acad Neurol , vol.16 , pp. 504-508
    • Zaheer, S.1    Beg, M.2    Rizvi, I.3
  • 105
    • 82355164323 scopus 로고    scopus 로고
    • Correlation of levels of neuronal and glial markers with radiological measures of infarct volume in ischaemic stroke: A systematic review
    • Ahmad O, Wardlaw J, Whiteley WN (2012) Correlation of levels of neuronal and glial markers with radiological measures of infarct volume in ischaemic stroke: a systematic review. Cerebrovasc Dis 33:47–54
    • (2012) Cerebrovasc Dis , vol.33 , pp. 47-54
    • Ahmad, O.1    Wardlaw, J.2    Whiteley, W.N.3
  • 106
    • 73249123600 scopus 로고    scopus 로고
    • Temporal profi le and clinical signifi cance of serum neuronspecifi c enolase and S100 in ischemic and hemorrhagic stroke
    • Brea D, Sobrino T, Blanco M et al (2009) Temporal profi le and clinical signifi cance of serum neuronspecifi c enolase and S100 in ischemic and hemorrhagic stroke. Clin Chem Lab Med 47:1513–1518
    • (2009) Clin Chem Lab Med , vol.47 , pp. 1513-1518
    • Brea, D.1    Sobrino, T.2    Blanco, M.3
  • 107
    • 79952200161 scopus 로고    scopus 로고
    • Serum neuron- specifi c enolase level as a biomarker in differential diagnosis of seizure and syncope
    • Lee SY, Choi YC, Kim JH et al (2010) Serum neuron- specifi c enolase level as a biomarker in differential diagnosis of seizure and syncope. J Neurol 257:1708–1712
    • (2010) J Neurol , vol.257 , pp. 1708-1712
    • Lee, S.Y.1    Choi, Y.C.2    Kim, J.H.3
  • 108
    • 33747056622 scopus 로고    scopus 로고
    • Practice parameter: Prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology
    • Wijdicks EF, Hijdra A, Young GB et al (2006) Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 67:203–210
    • (2006) Neurology , vol.67 , pp. 203-210
    • Wijdicks, E.F.1    Hijdra, A.2    Young, G.B.3
  • 109
    • 0037302055 scopus 로고    scopus 로고
    • Serum neuron-specifi c enolase predicts outcome in post-anoxic coma: A prospective cohort study
    • Meynaar IA, Oudemans-van Straaten HM, van der Wetering J et al (2003) Serum neuron-specifi c enolase predicts outcome in post-anoxic coma: a prospective cohort study. Intensive Care Med 29:189–195
    • (2003) Intensive Care Med , vol.29 , pp. 189-195
    • Meynaar, I.A.1    Oudemans-Van Straaten, H.M.2    Van Der Wetering, J.3
  • 110
    • 51349097706 scopus 로고    scopus 로고
    • Serum neuronspecifi c enolase as a predictor of short-term outcome and its correlation with Glasgow Coma Scale in traumatic brain injury
    • Guzel A, Er U, Tatli M et al (2008) Serum neuronspecifi c enolase as a predictor of short-term outcome and its correlation with Glasgow Coma Scale in traumatic brain injury. Neurosurg Rev 31:439–444
    • (2008) Neurosurg Rev , vol.31 , pp. 439-444
    • Guzel, A.1    Er, U.2    Tatli, M.3
  • 111
    • 77949915194 scopus 로고    scopus 로고
    • The prognostic value of neuron-specifi c enolase in head trauma patients
    • Meric E, Gunduz A, Turedi S et al (2010) The prognostic value of neuron-specifi c enolase in head trauma patients. J Emerg Med 38:297–301
    • (2010) J Emerg Med , vol.38 , pp. 297-301
    • Meric, E.1    Gunduz, A.2    Turedi, S.3
  • 112
    • 78650013269 scopus 로고    scopus 로고
    • GFAP and S100B are biomarkers of traumatic brain injury: An observational cohort study
    • Vos PE, Jacobs B, Andriessen TM et al (2010) GFAP and S100B are biomarkers of traumatic brain injury: an observational cohort study. Neurology 75:1786–1793
    • (2010) Neurology , vol.75 , pp. 1786-1793
    • Vos, P.E.1    Jacobs, B.2    Riessen, T.M.3
  • 113
    • 0026781011 scopus 로고
    • Neuronspecifi c enolase as a prognostic factor in metastatic malignant melanoma
    • Wibe E, Hannisdal E, Paus E et al (1992) Neuronspecifi c enolase as a prognostic factor in metastatic malignant melanoma. Eur J Cancer 28:1692–1695
    • (1992) Eur J Cancer , vol.28 , pp. 1692-1695
    • Wibe, E.1    Hannisdal, E.2    Paus, E.3
  • 114
    • 0031407773 scopus 로고    scopus 로고
    • S-100 and NSE as serum markers in melanoma
    • Tofani A, Cioffi RP, Sciuto R et al (1997) S-100 and NSE as serum markers in melanoma. Acta Oncol 36:761–764
    • (1997) Acta Oncol , vol.36 , pp. 761-764
    • Tofani, A.1    Cioffi, R.P.2    Sciuto, R.3
  • 115
    • 0025294088 scopus 로고
    • Electrophoretic assessment of aqueous and serum neurone-specifi c enolase in retinoblastoma and ocular malignant melanoma
    • Shine BS, Hungerford J, Vaghela B et al (1990) Electrophoretic assessment of aqueous and serum neurone-specifi c enolase in retinoblastoma and ocular malignant melanoma. Br J Ophthalmol 74:427–430
    • (1990) Br J Ophthalmol , vol.74 , pp. 427-430
    • Shine, B.S.1    Hungerford, J.2    Vaghela, B.3
  • 116
    • 0026501972 scopus 로고
    • Neuron-specifi c enolase – a serum tumour marker in seminoma?
    • Fosså SD, Klepp O, Paus E (1992) Neuron-specifi c enolase – a serum tumour marker in seminoma? Br J Cancer 65:297–299
    • (1992) Br J Cancer , vol.65 , pp. 297-299
    • Fosså, S.D.1    Klepp, O.2    Paus, E.3
  • 117
    • 0038200662 scopus 로고    scopus 로고
    • Neuron-specifi c enolase in testicular cancer – clinical experiences with serum neuron-specifi c enolase in patients with testicular cancer at diagnosis and during follow-up
    • Tandstad T, Klepp O (2003) Neuron-specifi c enolase in testicular cancer – clinical experiences with serum neuron-specifi c enolase in patients with testicular cancer at diagnosis and during follow-up. Acta Oncol 42:202–206
    • (2003) Acta Oncol , vol.42 , pp. 202-206
    • Tandstad, T.1    Klepp, O.2
  • 118
    • 0024544144 scopus 로고
    • Evaluation of gamma-enolase as a tumor marker for renal cell carcinoma
    • Takashi M, Haimoto H, Tanaka J et al (1989) Evaluation of gamma-enolase as a tumor marker for renal cell carcinoma. J Urol 141:830–834
    • (1989) J Urol , vol.141 , pp. 830-834
    • Takashi, M.1    Haimoto, H.2    Tanaka, J.3
  • 119
    • 0024726777 scopus 로고
    • Serum marker for Merkel cell tumour
    • Plowman PN (1989) Serum marker for Merkel cell tumour. Clin Radiol 40:542
    • (1989) Clin Radiol , vol.40
    • Plowman, P.N.1
  • 120
    • 0026476271 scopus 로고
    • Serum neurone-specifi c enolase levels in patients with neuroendocrine and carcinoid tumours
    • Cunningham RT, Johnston CF, Irvine GB et al (1992) Serum neurone-specifi c enolase levels in patients with neuroendocrine and carcinoid tumours. Clin Chim Acta 212:123–131
    • (1992) Clin Chim Acta , vol.212 , pp. 123-131
    • Cunningham, R.T.1    Johnston, C.F.2    Irvine, G.B.3
  • 121
    • 0024504284 scopus 로고
    • Neuron-specifi c enolase as a serum marker for immature teratoma and dysgerminoma
    • Kawata M, Sekiya S, Hatakeyama R et al (1989) Neuron-specifi c enolase as a serum marker for immature teratoma and dysgerminoma. Gynecol Oncol 32:191–197
    • (1989) Gynecol Oncol , vol.32 , pp. 191-197
    • Kawata, M.1    Sekiya, S.2    Hatakeyama, R.3
  • 122
    • 0025133121 scopus 로고
    • Neuropeptide Y and neuron-specifi c enolase levels in benign and malignant pheochromocytomas
    • Grouzmann E, Gicquel C, Plouin PF et al (1990) Neuropeptide Y and neuron-specifi c enolase levels in benign and malignant pheochromocytomas. Cancer 66:1833–1835
    • (1990) Cancer , vol.66 , pp. 1833-1835
    • Grouzmann, E.1    Gicquel, C.2    Plouin, P.F.3
  • 123
    • 0026781140 scopus 로고
    • Small cell undifferentiated carcinoma of the pancreas. Report of a patient with tumor marker studies
    • O’Connor TP, Wade TP, Sunwoo YC et al (1992) Small cell undifferentiated carcinoma of the pancreas. Report of a patient with tumor marker studies. Cancer 70:1514–1519
    • (1992) Cancer , vol.70 , pp. 1514-1519
    • O’Connor, T.P.1    Wade, T.P.2    Sunwoo, Y.C.3
  • 124
    • 0028207122 scopus 로고
    • Prognostic value of cerebrospinal fl uid neuronspecifi c enolase and S-100b protein in Guillain- Barré syndrome
    • Mokuno K, Kiyosawa K, Sugimura K et al (1994) Prognostic value of cerebrospinal fl uid neuronspecifi c enolase and S-100b protein in Guillain- Barré syndrome. Acta Neurol Scand 89:27–30
    • (1994) Acta Neurol Scand , vol.89 , pp. 27-30
    • Mokuno, K.1    Kiyosawa, K.2    Sugimura, K.3
  • 125
    • 0024796392 scopus 로고
    • Determination of glial fi brillary acidic protein, S100, myelin basic protein and neuron specifi c enolase in cerebrospinal fl uid from patients suffering from dementia
    • Vermuyten K (1989) Determination of glial fi brillary acidic protein, S100, myelin basic protein and neuron specifi c enolase in cerebrospinal fl uid from patients suffering from dementia. Acta Neurol Belg 89:318
    • (1989) Acta Neurol Belg , vol.89
    • Vermuyten, K.1
  • 126
    • 0035964161 scopus 로고    scopus 로고
    • Quantitation of 14-3-3 and neuron-specifi c enolase proteins in CSF in Creutzfeldt-Jakob disease
    • Aksamit AJ Jr, Preissner CM, Homburger HA (2001) Quantitation of 14-3-3 and neuron-specifi c enolase proteins in CSF in Creutzfeldt-Jakob disease. Neurology 57:728–730
    • (2001) Neurology , vol.57 , pp. 728-730
    • Aksamit, A.J.1    Preissner, C.M.2    Homburger, H.A.3
  • 127
    • 0026709279 scopus 로고
    • Cerebrospinal fl uid and serum levels of neuronspecifi c enolase in patients with schizophrenia
    • Egan MF, el-Mallakh RS, Suddath RL et al (1992) Cerebrospinal fl uid and serum levels of neuronspecifi c enolase in patients with schizophrenia. Psychiatry Res 43:187–195
    • (1992) Psychiatry Res , vol.43 , pp. 187-195
    • Egan, M.F.1    El-Mallakh, R.S.2    Suddath, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.