-
1
-
-
84878745222
-
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
-
Kadoch C, Hargreaves DC, Hodges C, et al. Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. Nat Genet 2013;45(6):592-601
-
(2013)
Nat Genet
, vol.45
, Issue.6
, pp. 592-601
-
-
Kadoch, C.1
Hargreaves, D.C.2
Hodges, C.3
-
2
-
-
77957731999
-
Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
-
Jones S, Wang TL, Shih Ie M, et al. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science 2010;330(6001):228-31
-
(2010)
Science
, vol.330
, Issue.6001
, pp. 228-231
-
-
Jones, S.1
Wang, T.L.2
Shih Ie, M.3
-
3
-
-
77957946398
-
ARID1A mutations in endometriosis-associated ovarian carcinomas
-
Wiegand KC, Shah SP, Al-Agha OM, et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med 2010;363(16):1532-43
-
(2010)
N Engl J Med
, vol.363
, Issue.16
, pp. 1532-1543
-
-
Wiegand, K.C.1
Shah, S.P.2
Al-Agha, O.M.3
-
4
-
-
84925502851
-
Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
-
Bitler BG, Aird KM, Garipov A, et al. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nat Med 2015;21(3):231-8
-
(2015)
Nat Med
, vol.21
, Issue.3
, pp. 231-238
-
-
Bitler, B.G.1
Aird, K.M.2
Garipov, A.3
-
5
-
-
77957955244
-
Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation
-
Wilson BG, Wang X, Shen X, et al. Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation. Cancer Cell 2010;18(4):316-28
-
(2010)
Cancer Cell
, vol.18
, Issue.4
, pp. 316-328
-
-
Wilson, B.G.1
Wang, X.2
Shen, X.3
-
6
-
-
84927547043
-
EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors
-
Fillmore CM, Xu C, Desai PT, et al. EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors. Nature 2015;520(7546):239-42
-
(2015)
Nature
, vol.520
, Issue.7546
, pp. 239-242
-
-
Fillmore, C.M.1
Xu, C.2
Desai, P.T.3
-
7
-
-
70350225510
-
Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex
-
Wang X, Sansam CG, Thom CS, et al. Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex. Cancer Res 2009;69(20):8094-101
-
(2009)
Cancer Res
, vol.69
, Issue.20
, pp. 8094-8101
-
-
Wang, X.1
Sansam, C.G.2
Thom, C.S.3
-
8
-
-
84896126029
-
ARID1B is a specific vulnerability in ARID1A-mutant cancers
-
Helming KC, Wang X, Wilson BG, et al. ARID1B is a specific vulnerability in ARID1A-mutant cancers. Nat Med 2014;20(3):251-4
-
(2014)
Nat Med
, vol.20
, Issue.3
, pp. 251-254
-
-
Helming, K.C.1
Wang, X.2
Wilson, B.G.3
-
9
-
-
84883467670
-
A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1
-
Oike T, Ogiwara H, Tominaga Y, et al. A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1. Cancer Res 2013;73(17):5508-18
-
(2013)
Cancer Res
, vol.73
, Issue.17
, pp. 5508-5518
-
-
Oike, T.1
Ogiwara, H.2
Tominaga, Y.3
-
10
-
-
80155131218
-
ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers
-
Guan B, Wang TL, Shih Ie M. ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers. Cancer Res 2011;71(21):6718-27
-
(2011)
Cancer Res
, vol.71
, Issue.21
, pp. 6718-6727
-
-
Guan, B.1
Wang, T.L.2
Shih Ie, M.3
-
11
-
-
84887840619
-
Nutlin-3 preferentially sensitises wild-type p53-expressing cancer cells to DR5-selective TRAIL over rhTRAIL
-
Meijer A, Kruyt FA, van der Zee AG, et al. Nutlin-3 preferentially sensitises wild-type p53-expressing cancer cells to DR5-selective TRAIL over rhTRAIL. Br J Cancer 2013;109(10):2685-95
-
(2013)
Br J Cancer
, vol.109
, Issue.10
, pp. 2685-2695
-
-
Meijer, A.1
Kruyt, F.A.2
Van Der Zee, A.G.3
-
12
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev LT, Vu BT, Graves B, et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 2004;303(5659):844-8
-
(2004)
Science
, vol.303
, Issue.5659
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
-
13
-
-
84895086287
-
A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: Protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation
-
Wiegand KC, Hennessy BT, Leung S, et al. A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation. BMC Cancer 2014;14:120
-
(2014)
BMC Cancer
, vol.14
, pp. 120
-
-
Wiegand, K.C.1
Hennessy, B.T.2
Leung, S.3
-
14
-
-
84923102594
-
Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling
-
Chandler RL, Damrauer JS, Raab JR, et al. Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling. Nat commun 2015;6:6118
-
(2015)
Nat Commun
, vol.6
, pp. 6118
-
-
Chandler, R.L.1
Damrauer, J.S.2
Raab, J.R.3
-
15
-
-
84906222663
-
Loss of ARID1A expression sensitizes cancer cells to PI3K-and AKT-inhibition
-
Samartzis EP, Gutsche K, Dedes KJ, et al. Loss of ARID1A expression sensitizes cancer cells to PI3K-and AKT-inhibition. Oncotarget 2014;5(14):5295-303
-
(2014)
Oncotarget
, vol.5
, Issue.14
, pp. 5295-5303
-
-
Samartzis, E.P.1
Gutsche, K.2
Dedes, K.J.3
-
16
-
-
33748367886
-
Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction
-
Park JH, Park EJ, Lee HS, et al. Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction. EMBO J 2006;25(17):3986-97
-
(2006)
EMBO J
, vol.25
, Issue.17
, pp. 3986-3997
-
-
Park, J.H.1
Park, E.J.2
Lee, H.S.3
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