Antibiotic resistance and mecA characterization of coagulase-negative staphylococci isolated from three hotels in London, UK

Frontiers in Microbiology

Volumn 6, Issue SEP, 2015, Pages

  Xu, Zhen ^a   Mkrtchyan, Hermine V ^a   Cutler, Ronald R ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Antibiotic resistance; Coagulase negative staphylococci; MecA gene; MLST; SCCmec typing

Indexed keywords

AMOXICILLIN; CEFEPIME; CHLORAMPHENICOL; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; OXACILLIN; PENICILLIN BINDING PROTEIN 2A; PENICILLIN DERIVATIVE; PSEUDOMONIC ACID; STREPTOMYCIN; TETRACYCLINE; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; BACTERIUM ISOLATION; COAGULASE NEGATIVE STAPHYLOCOCCUS; MINIMUM INHIBITORY CONCENTRATION; MULTILOCUS SEQUENCE TYPING; NONHUMAN; SOUTHERN BLOTTING; STAPHYLOCOCCUS COHNII; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS HAEMOLYTICUS; STAPHYLOCOCCUS HOMINIS; STAPHYLOCOCCUS WARNERI;

EID: 84946733197     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00947     Document Type: Article

References (27)

1. Andrews, J. M., and Howe, R. A. (2011). BSAC standardized disc susceptibility testing method (version 10). J. Antimicrob. Chemother. 66, 2726-2757. doi: 10.1093/jac/dkr359
2. Barbier, F., Lebeaux, D., Hernandez, D., Delannoy, A. S., Caro, V., François, P., and et al. (2011). High prevalence of the arginine catabolic mobile element in carriage isolates of methicillin-resistant Staphylococcus epidermidis. J. Antimicrob. Chemother. 66, 29-36. doi: 10.1093/jac/dkq410
3. Basaglia, G., Moras, L., Bearz, A., Scalone, S., and Paoli, P. D. (2003). Staphylococcus cohnii septicaemia in a patient with colon cancer. J. Med. Microbiol. 52, 101-102. doi: 10.1099/jmm.0.05002-0
4. Bouchami, O., Achour, W., Mekni, M. A., Rolo, J., and Ben Hassen, A. (2011a). Antibiotic resistance and molecular characterization of clinical isolates of methicillin-resistant coagulase-negative staphylococci isolated from bacteremic patients in oncohematology. Folia Microbiol. (Praha) 56, 122-130. doi: 10.1007/s12223-011-0017-1
5. Bouchami, O., Ben Hassen, A., de Lencastre, H., and Miragaia, M. (2011b). Molecular epidemiology of methicillin-resistant Staphylococcus hominis (MRSHo): low clonality and reservoirs of SCCmec structural elements. PLoS ONE 6:e21940. doi: 10.1371/journal.pone.0021940
6. Brennan, G. I., Shore, A. C., Corcoran, S., Tecklenborg, S., Coleman, D. C., and O'Connell, B. (2012). Emergence of hospital-and community-associated panton-valentine leukocidin-positive methicillin-resistant Staphylococcus aureus genotype ST772-MRSA-V in Ireland and detailed investigation of an ST772-MRSA-V cluster in a neonatal intensive care unit. J. Clin. Microbiol. 50, 841-847. doi: 10.1128/JCM.06354-11
7. Hanssen, A. M., Kjeldsen, G., and Sollid, J. U. (2004). Local variants of Staphylococcal cassette chromosome mec in sporadic methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative Staphylococci: evidence of horizontal gene transfer? Antimicrob. Agents Chemother. 48, 285-296. doi: 10.1128/AAC.48.1.285-296.2004
8. Huebner, J., and Goldmann, D. A. (1999). Coagulase-negative staphylococci: role as pathogens. Annu. Rev. Med. 50, 223-236. doi: 10.1146/annurev.med.50.1.223
9. Hussain, Z., Stoakes, L., Massey, V., Diagre, D., Fitzgerald, V., El Sayed, S., and et al. (2000). Correlation of oxacillin MIC with mecA gene carriage in coagulase-negative staphylococci. J. Clin. Microbiol. 38, 752-754.
10. IWG-SCC. (2009). Classification of staphylococcal cassette chromosome mec (SCCmec): guidelines for reporting novel SCCmec elements. Antimicrob. Agents Chemother. 53, 4961-4967. doi: 10.1128/AAC.00579-09
11. John, J. F., and Harvin, A. M. (2007). History and evolution of antibiotic resistance in coagulase-negative staphylococci: susceptibility profiles of new anti-staphylococci agents. Ther. Clin. Risk Manag. 3, 1143-1152.
12. Kinnevey, P. M., Shore, A. C., Brennan, G. I., Sullivan, D. J., Ehricht, R., Monecke, S., and et al. (2013). Emergence of sequence type 779 methicillin-resistant Staphylococcus aureus harboring a novel pseudo staphylococcal cassette chromosome mec (SCCmec)-SCC-SCCCRISPR composite element in Irish hospitals. Antimicrob. Agents Chemother. 57, 524-531. doi: 10.1128/AAC.01689-12
13. Kondo, Y., Ito, T., Ma, X. X., Watanabe, S., Kreiswirth, B. N., Etienne, J., and et al. (2007). Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions. Antimicrob. Agents Chemother. 51, 264-274. doi: 10.1128/AAC.00165-06
14. Li, M., Wang, X., Gao, Q., and Lu, Y. (2009). Molecular characterization of Staphylococcus epidermidis strains isolated from a teaching hospital in Shanghai, China. J. Med. Microbiol. 58, 456-461. doi: 10.1099/jmm.0.007567-0
15. Milheiriço, C., Oliveira, D. C., and de Lencastre, H. (2007). Update to the multiplex PCR strategy for assignment of mec element types in Staphylococcus aureus. Antimicrob. Agents Chemother. 51, 3374-3377. doi: 10.1128/AAC.00275-07
16. Mkrtchyan, H. V., Russell, C. A., Wang, N., and Cutler, R. R. (2013). Could public restrooms be an environment for bacterial resistomes? PLoS ONE 8:e54223. doi: 10.1371/journal.pone.0054223
17. Oliveira, D. C., Milheiriço, C., and de Lencastre, H. (2006). Redefining a structural variant of staphylococcal cassette chromosome mec, SCCmec type VI. Antimicrob. Agents Chemother. 50, 3457-3459. doi: 10.1128/AAC.00629-06
18. Roberts, M. C., Soge, O. O., No, D., Beck, N. K., and Meschke, J. S. (2011a). Isolation and characterization of methicillin-resistant Staphylococcus aureus from fire stations in two northwest fire districts. Am. J. Infect. Control. 39, 382-389. doi: 10.1016/j.ajic.2010.09.008
19. Roberts, M. C., Soge, O. O., No, D., Helgeson, S. E., and Meschke, J. S. (2011b). Characterization of Methicillin-resistant Staphylococcus aureus isolated from public surfaces on a university campus, student homes and local community. J. Appl. Microbiol. 110, 1531-1537. doi: 10.1111/j.1365-2672.2011.05017.x
20. Ruppé, E., Barbier, F., Mesli, Y., Maiga, A., Cojocaru, R., Benkhalfat, M., and et al. (2009). Diversity of staphylococcal cassette chromosome mec structures in methicillin-resistant Staphylococcus epidermidis and Staphylococcus haemolyticus strains among outpatients from four countries. Antimicrob. Agents Chemother. 53, 442-449. doi: 10.1128/AAC.00724-08
21. Shore, A. C., Deasy, E. C., Slickers, P., Brennan, G., O'Connell, B., Monecke, S., and et al. (2011). Detection of staphylococcal cassette chromosome mec type XI carrying highly divergent mecA, mecI, mecR1, blaZ, and ccr genes in human clinical isolates of clonal complex 130 methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 55, 3765-3773. doi: 10.1128/AAC.00187-11
22. Simões, R. R., Aires-de-Sousa, M., Conceição, T., Antunes, F., da Costa, P. M., and de Lencastre, H. (2011). High prevalence of EMRSA-15 in Portuguese public buses: a worrisome finding. PLoS ONE 6:e17630. doi: 10.1371/journal.pone.0017630
23. Soge, O. O., Meschke, J. S., No, D. B., and Roberts, M. C. (2009). Characterization of methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative Staphylococcus spp. isolated from US West Coast public marine beaches. J. Antimicrob. Chemother. 64, 1148-1155. doi: 10.1093/jac/dkp368
24. Thomas, J. C., Vargas, M. R., Miragaia, M., Peacock, S. J., Archer, G. L., and Enright, M. C. (2007). Improved multilocus sequence typing scheme for Staphylococcus epidermidis. J. Clin. Microbiol. 45, 616-619. doi: 10.1128/JCM.01934-06
25. Tulinski, P., Fluit, A. C., Wagenaar, J. A., Mevius, D., van de Vijver, L., and Duim, B. (2012). Methicillin-resistant coagulase-negative staphylococci on pig farms as a reservoir of heterogeneous staphylococcal cassette chromosome mec elements. Appl. Environ. Microbiol. 78, 299-304. doi: 10.1128/AEM.05594-11
26. Zhang, K., McClure, J. A., Elsayed, S., and Conly, J. M. (2009). Novel staphylococcal cassette chromosome mec type, tentatively designated type VIII, harboring class A mec and type 4 ccr gene complexes in a Canadian epidemic strain of methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 53, 531-540. doi: 10.1128/AAC.01118-08
27. Zong, Z., Peng, C., and Lü, X. (2011). Diversity of SCCmec elements in methicillin-resistant coagulase-negative staphylococci clinical isolates. PLoS ONE 6:e20191. doi: 10.1371/journal.pone.0020191