메뉴 건너뛰기




Volumn 20, Issue 11, 2015, Pages 1247-1252

Clinicopathologic features associated with human papillomavirus/pl6 in patients with metastatic squamous cell carcinoma of the anal canal

Author keywords

Anal canal; Anus neoplasms; Human papillomavirus; Immunohistochemistry; In situ hybridization; p16

Indexed keywords

PROTEIN P16;

EID: 84946553998     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2015-0091     Document Type: Article
Times cited : (34)

References (48)
  • 2
    • 3042820395 scopus 로고    scopus 로고
    • Anal cancer incidence and survival: The Surveillance, Epidemiology, and End Results experience, 1973-2000
    • Johnson LG, Madeleine MM, Newcomer LM et al. Anal cancer incidence and survival: The Surveillance, Epidemiology, and End Results experience, 1973-2000. Cancer 2004;101:281-288.
    • (2004) Cancer , vol.101 , pp. 281-288
    • Johnson, L.G.1    Madeleine, M.M.2    Newcomer, L.M.3
  • 3
    • 0031004470 scopus 로고    scopus 로고
    • Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: Results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups
    • Bartelink H, Roelofsen F, Eschwege F et al. Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: Results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. J Clin Oncol 1997;15:20400-2049.
    • (1997) J Clin Oncol , vol.15 , pp. 20400-22049
    • Bartelink, H.1    Roelofsen, F.2    Eschwege, F.3
  • 4
    • 9544252934 scopus 로고    scopus 로고
    • Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: Results of a phase III randomized intergroup study
    • Flam M, John M, Pajak TF et al. Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: Results of a phase III randomized intergroup study. J Clin Oncol 1996;14: 2527-2539.
    • (1996) J Clin Oncol , vol.14 , pp. 2527-2539
    • Flam, M.1    John, M.2    Pajak, T.F.3
  • 5
    • 34648837440 scopus 로고    scopus 로고
    • Outcomes of salvage surgery for squamous cell carcinoma of the anal canal
    • Schiller DE, Cummings BJ, Rai S et al. Outcomes of salvage surgery for squamous cell carcinoma of the anal canal. Ann Surg Oncol 2007;14: 2780-2789.
    • (2007) Ann Surg Oncol , vol.14 , pp. 2780-2789
    • Schiller, D.E.1    Cummings, B.J.2    Rai, S.3
  • 6
    • 34249319133 scopus 로고    scopus 로고
    • Predictors and patterns of recurrence after definitive chemoradiation foranal cancer
    • Das P, Bhatia S, Eng C et al. Predictors and patterns of recurrence after definitive chemoradiation foranal cancer. IntJ Radiat Oncol Biol Phys2007; 68:794-800.
    • Intj Radiat Oncol Biol Phys2007 , vol.68 , pp. 794-800
    • Das, P.1    Bhatia, S.2    Eng, C.3
  • 7
    • 33846592866 scopus 로고    scopus 로고
    • Results of surgical salvage after failed chemoradia-tion therapy for epidermoid carcinoma of the anal canal
    • Mullen JT, Rodriguez-Bigas MA, Chang GJ et al. Results of surgical salvage after failed chemoradia-tion therapy for epidermoid carcinoma of the anal canal. Ann Surg Oncol 2007;14:478-483.
    • (2007) Ann Surg Oncol , vol.14 , pp. 478-483
    • Mullen, J.T.1    Rodriguez-Bigas, M.A.2    Chang, G.J.3
  • 8
    • 33750092284 scopus 로고    scopus 로고
    • Anal cancer: Current and future methodology
    • Eng C. Anal cancer: Current and future methodology. Cancer Invest 2006;24:535-544.
    • (2006) Cancer Invest , vol.24 , pp. 535-544
    • Eng, C.1
  • 9
    • 33644780868 scopus 로고    scopus 로고
    • Metastatic anal cancer: The search for cure
    • Cummings BJ. Metastatic anal cancer: The search for cure. Onkologie 2006;29:5-6.
    • (2006) Onkologie , vol.29 , pp. 5-6
    • Cummings, B.J.1
  • 10
    • 0030693377 scopus 로고    scopus 로고
    • Sexually transmitted infection as a cause of anal cancer
    • Frisch M, Glimelius B, van den Brule AJ et al. Sexually transmitted infection as a cause of anal cancer. N Engl J Med 1997;337:1350-1358.
    • (1997) N Engl J Med , vol.337 , pp. 1350-1358
    • Frisch, M.1    Glimelius, B.2    Van Den Brule, A.J.3
  • 11
    • 61449242932 scopus 로고    scopus 로고
    • Prevalence and type distribution of human papillo-mavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: A meta-analysis
    • DeVuyst H, Clifford GM, Nascimento MC et al. Prevalence and type distribution of human papillo-mavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: A meta-analysis. IntJ Cancer 2009;124:1626-1636.
    • (2009) Intj Cancer , vol.124 , pp. 1626-1636
    • Devuyst, H.1    Clifford, G.M.2    Nascimento, M.C.3
  • 12
    • 64249163284 scopus 로고    scopus 로고
    • Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions
    • Hoots BE, Palefsky JM, Pimenta JM et al. Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions. Int J Cancer 2009;124:2375-2383.
    • (2009) Int J Cancer , vol.124 , pp. 2375-2383
    • Hoots, B.E.1    Palefsky, J.M.2    Pimenta, J.M.3
  • 13
    • 84861742303 scopus 로고    scopus 로고
    • Human papillomavirus-associated cancers-United States, 2004-2008
    • Centers for Disease Control and Prevention (CDC)
    • Centers for Disease Control and Prevention (CDC). Human papillomavirus-associated cancers-United States, 2004-2008. MMWR Morb Mortal Wkly Rep 2012;61:258-261.
    • (2012) MMWR Morb Mortal Wkly Rep , vol.61 , pp. 258-261
  • 14
    • 0025271203 scopus 로고
    • Association of human papillomavirus types 16 and 18 E6 proteinswith p53
    • Werness BA, Levine AJ, Howley PM. Association of human papillomavirus types 16 and 18 E6 proteinswith p53. Science 1990;248:76-79.
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 15
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papilloma-virus types 16 and 18 promotes the degradation of p53
    • Scheffner M, Werness BA, Huibregtse JM et al. The E6 oncoprotein encoded by human papilloma-virus types 16 and 18 promotes the degradation of p53. Cell 1990;63:1129-1136.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3
  • 16
    • 8944239884 scopus 로고    scopus 로고
    • High-risk human papillomavirus E6 protein has two distinct binding sites within p53, of which only one determines degradation
    • Li X, Coffino P. High-risk human papillomavirus E6 protein has two distinct binding sites within p53, of which only one determines degradation. J Virol 1996;70:4509-4516.
    • (1996) J Virol , vol.70 , pp. 4509-4516
    • Li, X.1    Coffino, P.2
  • 17
    • 3042813439 scopus 로고    scopus 로고
    • Unique and overlappingfunctionsof pRband p107 in the control of proliferation and differentiation in epidermis
    • Ruiz S, Santos M, Segrelles C et al. Unique and overlappingfunctionsof pRband p107 in the control of proliferation and differentiation in epidermis. Development 2004;131:2737-2748.
    • (2004) Development , vol.131 , pp. 2737-2748
    • Ruiz, S.1    Santos, M.2    Segrelles, C.3
  • 18
    • 0345060052 scopus 로고    scopus 로고
    • Recapitulation of the effects of the human papillo-mavirustype 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo
    • Balsitis SJ, Sage J, Duensing S et al. Recapitulation of the effects of the human papillo-mavirustype 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Mol Cell Biol 2003;23:9094-9103.
    • (2003) Mol Cell Biol , vol.23 , pp. 9094-9103
    • Balsitis, S.J.1    Sage, J.2    Duensing, S.3
  • 19
    • 33745906528 scopus 로고    scopus 로고
    • Retinoblastoma tumor suppressor: Where cancer meets the cell cycle
    • Knudsen ES, Knudsen KE. Retinoblastoma tumor suppressor: Where cancer meets the cell cycle. Exp Biol Med (Maywood) 2006;231: 1271-1281.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 1271-1281
    • Knudsen, E.S.1    Knudsen, K.E.2
  • 20
    • 77950360188 scopus 로고    scopus 로고
    • Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation
    • Ajani JA, Wang X, Izzo JG et al. Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation. Dig Dis Sci 2010;55:1098-1105.
    • (2010) Dig Dis Sci , vol.55 , pp. 1098-1105
    • Ajani, J.A.1    Wang, X.2    Izzo, J.G.3
  • 21
    • 3042782708 scopus 로고    scopus 로고
    • Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer
    • Daling JR, Madeleine MM, Johnson LG et al. Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer. Cancer 2004;101: 270-280.
    • (2004) Cancer , vol.101 , pp. 270-280
    • Daling, J.R.1    Madeleine, M.M.2    Johnson, L.G.3
  • 22
    • 0034692433 scopus 로고    scopus 로고
    • Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome
    • Frisch M, Biggar RJ, Goedert JJ. Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome. J Natl Cancer Inst 2000;92:1500-1510.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1500-1510
    • Frisch, M.1    Biggar, R.J.2    Goedert, J.J.3
  • 23
    • 77954437154 scopus 로고    scopus 로고
    • Immunosuppressive disorders and risk of anal squamous cell carcinoma: A nationwide cohort study in Denmark, 1978-2005
    • Sunesen KG, Norgaard M, Thorlacius-Ussing O et al. Immunosuppressive disorders and risk of anal squamous cell carcinoma: A nationwide cohort study in Denmark, 1978-2005. Int J Cancer 2010; 127:675-684.
    • (2010) Int J Cancer , vol.127 , pp. 675-684
    • Sunesen, K.G.1    Norgaard, M.2    Thorlacius-Ussing, O.3
  • 25
    • 77957835319 scopus 로고    scopus 로고
    • Long-term absolute risk of cervical intraepithelial neoplasia grade 3 or worse following human papillomavirus infection: Role of persistence
    • Kjaer SK, Frederiksen K, Munk C et al. Long-term absolute risk of cervical intraepithelial neoplasia grade 3 or worse following human papillomavirus infection: Role of persistence. J Natl Cancer Inst 2010;102:1478-1488.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 1478-1488
    • Kjaer, S.K.1    Frederiksen, K.2    Munk, C.3
  • 26
    • 77749279734 scopus 로고    scopus 로고
    • Longitudinal study of human papillomavirus persistence and cervical intraepithelial neoplasia grade 2/3: Critical role of duration of infection
    • Rodriguez AC, Schiffman M, Herrero R et al. Longitudinal study of human papillomavirus persistence and cervical intraepithelial neoplasia grade 2/3: Critical role of duration of infection. J Natl Cancer Inst 2010;102:315-324.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 315-324
    • Rodriguez, A.C.1    Schiffman, M.2    Herrero, R.3
  • 27
    • 0034600339 scopus 로고    scopus 로고
    • Evidence for a causal association between human papillomavirus and a subset of head and neck cancers
    • Gillison ML, Koch WM, Capone RB et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 2000;92:709-720.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 709-720
    • Gillison, M.L.1    Koch, W.M.2    Capone, R.B.3
  • 28
    • 34248350674 scopus 로고    scopus 로고
    • Case-control study of human papillomavirus and oropharyngeal cancer
    • D'Souza G, Kreimer AR, Viscidi R et al. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 2007;356:1944-1956.
    • (2007) N Engl J Med , vol.356 , pp. 1944-1956
    • D'souza, G.1    Kreimer, A.R.2    Viscidi, R.3
  • 29
    • 34648825016 scopus 로고    scopus 로고
    • Cinciripini PM. Trends in head and neck cancer incidence in relation to smoking prevalence: An emerging epidemic of human papillomavirus-associated cancers?
    • Sturgis EM, Cinciripini PM. Trends in head and neck cancer incidence in relation to smoking prevalence: An emerging epidemic of human papillomavirus-associated cancers? Cancer 2007; 110:1429-1435.
    • (2007) Cancer , vol.110 , pp. 1429-1435
    • Sturgis, E.M.1
  • 30
    • 23244462578 scopus 로고    scopus 로고
    • Penile cancer: Importance of circumcision, human papillomavirus and smoking in in situ and invasive disease
    • Daling JR, Madeleine MM, Johnson LG et al. Penile cancer: Importance of circumcision, human papillomavirus and smoking in in situ and invasive disease. IntJ Cancer 2005;116:606-616.
    • (2005) Intj Cancer , vol.116 , pp. 606-616
    • Daling, J.R.1    Madeleine, M.M.2    Johnson, L.G.3
  • 31
    • 0026592992 scopus 로고
    • Detection of human papillomavirus in squamous neoplasm of the penis
    • Sarkar FH, Miles BJ, Plieth DH et al. Detection of human papillomavirus in squamous neoplasm of the penis. J Urol 1992;147:389-392.
    • (1992) J Urol , vol.147 , pp. 389-392
    • Sarkar, F.H.1    Miles, B.J.2    Plieth, D.H.3
  • 32
    • 84867572404 scopus 로고    scopus 로고
    • Prevalence of human papillomavirus types in invasive vulvar cancers and vulvar intraepithelial neoplasia 3 in the United States before vaccine introduction
    • Gargano JW, Wilkinson EJ, Unger ER et al. Prevalence of human papillomavirus types in invasive vulvar cancers and vulvar intraepithelial neoplasia 3 in the United States before vaccine introduction. J Low Genit Tract Dis 2012;16: 471-479.
    • (2012) J Low Genit Tract Dis , vol.16 , pp. 471-479
    • Gargano, J.W.1    Wilkinson, E.J.2    Unger, E.R.3
  • 33
    • 39649109915 scopus 로고    scopus 로고
    • Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial
    • Fakhry C, Westra WH, Li S et al. Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 2008; 100:261-269.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 261-269
    • Fakhry, C.1    Westra, W.H.2    Li, S.3
  • 34
    • 77957955293 scopus 로고    scopus 로고
    • Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial
    • Rischin D, Young RJ, Fisher R et al. Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial. J Clin Oncol 2010;28: 4142-4148.
    • (2010) J Clin Oncol , vol.28 , pp. 4142-4148
    • Rischin, D.1    Young, R.J.2    Fisher, R.3
  • 35
    • 65349173893 scopus 로고    scopus 로고
    • Effect of HPV-associated p16INK4A expression on response to radiotherapyand survival in squamous cell carcinoma of the head and neck
    • Lassen P, Eriksen JG, Hamilton-Dutoit S et al. Effect of HPV-associated p16INK4A expression on response to radiotherapyand survival in squamous cell carcinoma of the head and neck. J Clin Oncol 2009;27:1992-1998.
    • (2009) J Clin Oncol , vol.27 , pp. 1992-1998
    • Lassen, P.1    Eriksen, J.G.2    Hamilton-Dutoit, S.3
  • 36
    • 34548680936 scopus 로고    scopus 로고
    • Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: Reviewand meta-analysis
    • Ragin CC, Taioli E. Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: Reviewand meta-analysis. IntJ Cancer 2007;121:1813-1820.
    • (2007) Intj Cancer , vol.121 , pp. 1813-1820
    • Ragin, C.C.1    Taioli, E.2
  • 37
    • 77954190940 scopus 로고    scopus 로고
    • Human papillomavirus and survival of patients with oro-pharyngeal cancer
    • Ang KK, Harris J, Wheeler R et al. Human papillomavirus and survival of patients with oro-pharyngeal cancer. N Engl J Med 2010;363:24-35.
    • (2010) N Engl J Med , vol.363 , pp. 24-35
    • Ang, K.K.1    Harris, J.2    Wheeler, R.3
  • 38
    • 84905842870 scopus 로고    scopus 로고
    • Human papillomavirusgenotyping and p16 expression as prognostic factors for patients with American Joint Committee on Cancer stages I to III carcinoma of the anal canal
    • Serup-Hansen E, Linnemann D, Skovrider-Ruminski Wetal. Human papillomavirusgenotyping and p16 expression as prognostic factors for patients with American Joint Committee on Cancer stages I to III carcinoma of the anal canal. J Clin Oncol 2014;32:1812-1817.
    • (2014) J Clin Oncol , vol.32 , pp. 1812-1817
    • Serup-Hansen, E.1    Linnemann, D.2    Wetal, S.-R.3
  • 39
    • 77954818058 scopus 로고    scopus 로고
    • The American Joint Committee on Cancer: The 7th edition of the AJCC cancer staging manual and the future of TNM
    • Edge SB, Compton CC. The American Joint Committee on Cancer: The 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol 2010;17:1471-1474.
    • Ann Surg Oncol 2010 , vol.17 , pp. 1471-1474
    • Edge, S.B.1    Compton, C.C.2
  • 40
    • 79960924367 scopus 로고    scopus 로고
    • The prognostic significance of tumor human papillomavirus status for patients with anal squamous cell carcinoma treated with combined chemoradiotherapy
    • Yhim HY, Lee NR, Song EKetal.The prognostic significance of tumor human papillomavirus status for patients with anal squamous cell carcinoma treated with combined chemoradiotherapy. Int J Cancer 2011;129:1752-1760.
    • (2011) Int J Cancer , vol.129 , pp. 1752-1760
    • Yhim, H.Y.1    Lee, N.R.2    Eketal, S.3
  • 41
    • 0344628629 scopus 로고    scopus 로고
    • Risk factors for anal cancer: Results of a population-based case-control study
    • Tseng HF, Morgenstern H, Mack TM et al. Risk factors for anal cancer: Results of a population-based case-control study. Cancer Causes Control 2003;14:837-846.
    • (2003) Cancer Causes Control , vol.14 , pp. 837-846
    • Tseng, H.F.1    Morgenstern, H.2    Mack, T.M.3
  • 42
    • 68449103669 scopus 로고    scopus 로고
    • Incidence trends of invasive cervical cancer in the United States by combined race and ethnicity
    • Barnholtz-Sloan J, Patel N, Rollison D et al. Incidence trends of invasive cervical cancer in the United States by combined race and ethnicity. Cancer Causes Control 2009;20:1129-1138.
    • (2009) Cancer Causes Control , vol.20 , pp. 1129-1138
    • Barnholtz-Sloan, J.1    Patel, N.2    Rollison, D.3
  • 43
    • 33646367200 scopus 로고    scopus 로고
    • The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: Correlation with important high-risk prognostic factors
    • Ghebeh H, Mohammed S, Al-Omair A et al. The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: Correlation with important high-risk prognostic factors. Neoplasia 2006;8:190-198.
    • (2006) Neoplasia , vol.8 , pp. 190-198
    • Ghebeh, H.1    Mohammed, S.2    Al-Omair, A.3
  • 44
    • 27644562256 scopus 로고    scopus 로고
    • Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma
    • Thompson RH, Gillett MD, Cheville JC et al. Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma. Cancer 2005;104:2084-2091.
    • (2005) Cancer , vol.104 , pp. 2084-2091
    • Thompson, R.H.1    Gillett, M.D.2    Cheville, J.C.3
  • 45
    • 82255179501 scopus 로고    scopus 로고
    • Relationship between the expressions of PD-L1 and tumor-infiltrating lymphocytes in oral squamous cell carcinoma
    • Cho YA, Yoon HJ, Lee JI et al. Relationship between the expressions of PD-L1 and tumor-infiltrating lymphocytes in oral squamous cell carcinoma. Oral Oncol 2011;47:1148-1153.
    • (2011) Oral Oncol , vol.47 , pp. 1148-1153
    • Cho, Y.A.1    Yoon, H.J.2    Lee, J.I.3
  • 46
    • 84875475811 scopus 로고    scopus 로고
    • Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
    • Lyford-Pike S, Peng S, Young GD et al. Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res 2013; 73:1733-1741.
    • (2013) Cancer Res , vol.73 , pp. 1733-1741
    • Lyford-Pike, S.1    Peng, S.2    Young, G.D.3
  • 47
    • 84904537792 scopus 로고    scopus 로고
    • National, regional, state, and selected local area vaccination coverage among adolescents aged 13-17 years—United States, 2013
    • Elam-Evans LD, Yankey D, Jeyarajah J et al. National, regional, state, and selected local area vaccination coverage among adolescents aged 13-17 years—United States, 2013. MMWR Morb Mortal Wkly Rep 2014;63:625-633.
    • (2014) MMWR Morb Mortal Wkly Rep , vol.63 , pp. 625-633
    • Elam-Evans, L.D.1    Yankey, D.2    Jeyarajah, J.3
  • 48
    • 84923039975 scopus 로고    scopus 로고
    • A 9-valent HPV vaccine against infection and intraepithelial neoplasia in women
    • Joura EA, Giuliano AR, Iversen OE et al. A 9-valent HPV vaccine against infection and intraepithelial neoplasia in women. N Engl J Med 2015; 372:711-723.
    • (2015) N Engl J Med , vol.372 , pp. 711-723
    • Joura, E.A.1    Giuliano, A.R.2    Iversen, O.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.