Outcomes of salvage surgery for squamous cell carcinoma of the anal canal

Annals of Surgical Oncology

Volumn 14, Issue 10, 2007, Pages 2780-2789

  Schiller, Dan E ^a   Cummings, Bernard J ^b   Rai, Sundeep ^a   Le, Lisa W ^b   Last, Linda ^c   Davey, Phil ^c   Easson, Alexandra ^a,b   Smith, Andrew J ^c   Swallow, Carol J ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

Author keywords

Anal Cancer; Combined Modality Therapy; Salvage Surgery; Squamous Cell Carcinoma

Indexed keywords

ADULT; AGED; ANAL CANAL; ANUS CARCINOMA; ARTICLE; CANCER INVASION; CANCER PATIENT; CANCER REGISTRY; CANCER SIZE; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL PROTOCOL; COMORBIDITY; DISEASE FREE INTERVAL; FEMALE; HUMAN; KAPLAN MEIER METHOD; LOG RANK TEST; MALE; MULTIVARIATE ANALYSIS; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PATIENT SELECTION; POSTOPERATIVE PERIOD; PREDICTION; RECTUM ABDOMINOPERINEAL RESECTION; SALVAGE THERAPY; SQUAMOUS CELL CARCINOMA; SURGICAL MORTALITY; SURGICAL PATIENT; SURVIVAL RATE; SURVIVAL TIME; SURVIVOR; TREATMENT OUTCOME; UNIVARIATE ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; ANAL CANAL; ANUS NEOPLASMS; CANCER CARE FACILITIES; CARCINOMA, SQUAMOUS CELL; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; NEOPLASM, RESIDUAL; ONTARIO; REGISTRIES; REOPERATION; RETROSPECTIVE STUDIES; SALVAGE THERAPY;

EID: 34648837440     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-007-9491-8     Document Type: Article

References (27)

1. Moore HG, Guillem JG. Anal neoplasms. Surg Clin North Am 2002; 82:1233-1251
2. Nigro ND, Vaitkevicius VK, Considine B Jr. Combined therapy for cancer of the anal canal: a preliminary report. Dis Colon Rectum 1974; 17:354-356
3. Cummings BJ. Concomitant radiotherapy and chemotherapy for anal cancer. Semin Oncol 1992; 19:102-108
4. Fuchshuber PR, Rodriguez-Bigas M, Weber T, Petrelli NJ. Anal canal and perianal epidermoid cancers. J Am Coll Surg 1997; 185:494-505
5. Golden GT, Horsley JS III. Surgical management of epidermoid carcinoma of the anus. Am J Surg 1976; 131:275-280
6. Meeker WR Jr. et al. Combined chemotherapy, radiation, and surgery for epithelial cancer of the anal canal. Cancer 1986; 57:525-529
7. Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research. Lancet 1996; 348:1049-1054
8. Bartelink H, et al. Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. J Clin Oncol 1997; 15:2040-2049
9. Papillon J. Effectiveness of combined radio-chemotherapy in the management of epidermoid carcinoma of the anal canal. Int J Radiat Oncol Biol Phys 1990; 19:1217-1218
10. Tanum G, Tveit K, Karlsen KO, Hauer-Jensen M. Chemotherapy and radiation therapy for anal carcinoma. Survival and late morbidity. Cancer 1991; 67:2462-2466
11. Cummings BJ, Keane TJ, O'Sullivan B, Wong CS, Catton CN. Epidermoid anal cancer: treatment by radiation alone or by radiation and 5-fluorouracil with and without mitomycin C. Int J Radiat Oncol Biol Phys 1991; 21:1115-1125
12. Klas JV, Rothenberger DA, Wong WD, Madoff RD. Malignant tumors of the anal canal: the spectrum of disease, treatment, and outcomes. Cancer 1999; 85:1686-1693
13. Akbari RP, et al. Oncologic outcomes of salvage surgery for epidermoid carcinoma of the anus initially managed with combined modality therapy. Dis Colon Rectum 2004; 47:1136-1144
14. Allal AS, Laurencet FM, Reymond MA, Kurtz JM, Marti MC. Effectiveness of surgical salvage therapy for patients with locally uncontrolled anal carcinoma after sphincter-conserving treatment. Cancer 1999; 86:405-409
15. Ellenhorn JD, Enker WE, Quan SH. Salvage abdominoperineal resection following combined chemotherapy and radiotherapy for epidermoid carcinoma of the anus. Ann Surg Oncol 1994; 1:105-110
16. Ferenschild FT, et al. Salvage abdominoperineal resection and perineal wound healing in local recurrent or persistent anal cancer. World J Surg 2005; 29:1452-1457
17. Nilsson PJ, Svensson C, Goldman S, Glimelius B. Salvage abdominoperineal resection in anal epidermoid cancer. Br J Surg 2002; 89:1425-1429
18. Pocard M, Tiret E, Nugent K, Dehni N, Parc R. Results of salvage abdominoperineal resection for anal cancer after radiotherapy. Dis Colon Rectum 1998; 41:1488-1493
19. van der Wal BC, Cleffken BI, Gulec B, Kaufman HS, Choti MA. Results of salvage abdominoperineal resection for recurrent anal carcinoma following combined chemoradiation therapy. J Gastrointest Surg 2001; 5:383-387
20. Renehan AG, Saunders MP, Schofield PF, O'Dwyer ST. Patterns of local disease failure and outcome after salvage surgery in patients with anal cancer. Br J Surg 2005; 92:605-614
21. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40:373-383
22. Papaconstantinou HT, Bullard KM, Rothenberger DA, Madoff RD. Salvage abdominoperineal resection after failed Nigro protocol: modest success, major morbidity. Colorectal Dis 2006; 8:124-129
23. Chessin DB, et al. Rectus flap reconstruction decreases perineal wound complications after pelvic chemoradiation and surgery: a cohort study. Ann Surg Oncol 2005; 12:104-110
24. Tokar M, Bobilev D, Zalmanov S, Geffen DB, Walfisch S. Combined multimodal approach to the treatment of metastatic anal carcinoma: report of a case and review of the literature. Onkologie 2006; 29:30-32
25. Smith AJ, Whelan P, Cummings BJ, Stern HS. Management of persistent or locally recurrent epidermoid cancer of the anal canal with abdominoperineal resection. Acta Oncol 2001; 40:34-36
26. Ghouti L, et al. Salvage abdominoperineal resection after failure of conservative treatment in anal epidermoid cancer. Dis Colon Rectum 2005; 48:16-22
27. Bai YK, Cao WL, Gao JD, Liang J, Shao YF. Surgical salvage therapy of anal cancer. World J Gastroenterol 2004; 10:424-426