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Volumn 23, Issue 17, 2015, Pages 5489-5495
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Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype A
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Author keywords
BoNT A LC inhibitor; Botulinum neurotoxin; HTP in silico screening; SNAP 25; SNAPtide
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Indexed keywords
2 [2 [[1 (2 FLUOROBENZYL) 2,5 DIOXOIMIDAZOLIDIN 4 YLIDENE]METHYL]PHENOXY] N (4 FLUOROPHENYL)ACETAMIDE;
2 [3 [[1 (2 FLUOROBENZYL) 2,5 DIOXOIMIDAZOLIDIN 4 YLIDENE]METHYL]PHENOXY] N (4 FLUOROPHENYL)ACETAMIDE;
2 [4 [[1 (2 FLUOROBENZYL) 2,5 DIOXOIMIDAZOLIDIN 4 YLIDENE]METHYL]PHENOXY] N (4 FLUOROPHENYL)ACETAMIDE;
3 (2 FLUOROBENZYL)IMIDAZOLIDINE 2,4 DIONE;
4 TRIFLUOROMETHYL N HYDROXYBENZAMIDINE;
5 CHLOROETHYL 3 (4 TRIFLUOROMETHYLPHENYL) [1,2,4] OXADIAZOLE;
6,7 METHYLENEDIOXYQUINAZOLINE 2,4(1H,3H) DIONE;
BOTULINUM ANTISERUM;
BOTULINUM TOXIN A;
METHYL 6 AMINO 1,3 BENZODIOXOLE 5 CARBOXYLATE;
METHYL 6 NITRO 1,3 BENZODIOXOLE 5 CARBOXYLATE;
N (4 FLUOROPHENYL) 2 (2 FORMYLPHENOXY)ACETAMIDE;
N (4 FLUOROPHENYL) 2 (3 FORMYLPHENOXY)ACETAMIDE;
N (4 FLUOROPHENYL) 2 (4 FORMYLPHENOXY)ACETAMIDE;
SB BN 01;
SB BN 02;
UNCLASSIFIED DRUG;
NEUROTOXIN;
PROTEINASE INHIBITOR;
ARTICLE;
CELL LINE;
COMPUTER ANALYSIS;
COMPUTER MODEL;
DRUG ACTIVITY;
DRUG IDENTIFICATION;
DRUG POTENCY;
DRUG SCREENING;
DRUG SYNTHESIS;
HIGH THROUGHPUT SCREENING;
IN VITRO STUDY;
NEURO 2A CELL;
ANIMAL;
ANTAGONISTS AND INHIBITORS;
CHEMICAL STRUCTURE;
CHEMISTRY;
DRUG DESIGN;
HUMAN;
SYNTHESIS;
ANIMALS;
BOTULINUM TOXINS, TYPE A;
DRUG DESIGN;
HUMANS;
MODELS, MOLECULAR;
NEUROTOXINS;
PROTEASE INHIBITORS;
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EID: 84946496898
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2015.07.040 Document Type: Article |
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Times cited : (13)
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References (23)
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