Elevated excretion of biopyrrin as a new marker for idiopathic Parkinson's disease

Parkinsonism and Related Disorders

Volumn 21, Issue 11, 2015, Pages 1371-1372

  Luan, Hemi ^a   Liu, Liang Feng ^a   Tang, Zhi ^a   Mok, Vincent C T ^b   Li, Min ^a   Cai, Zongwei ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b Prince of Wales Hospital   (Hong Kong)

Author keywords

Biopyrrin; Enzyme linked immunosorbent assay; Marker; Metabolic profiling

Indexed keywords

BIOPYRRIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; BILIRUBIN; BIOLOGICAL MARKER;

CASE CONTROL STUDY; DISEASE MARKER; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; HOEHN AND YAHR SCALE; HUMAN; IDIOPATHIC PARKINSON DISEASE; LETTER; METABOLOMICS; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; SENSITIVITY AND SPECIFICITY; HONG KONG; METABOLISM; METABOLOME; URINE;

BILIRUBIN; BIOMARKERS; CASE-CONTROL STUDIES; HONG KONG; HUMANS; METABOLOME; PARKINSON DISEASE;

EID: 84946487098     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2015.09.009     Document Type: Letter

References (5)

1. de Lau L.M., Breteler M.M. Epidemiology of Parkinson's disease. Lancet Neurol. 2006, 5:525-535.
2. Alexander G.E. Biology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorder. Dialogues Clin. Neurosci. 2004, 6:259-280.
3. Ahlskog J.E. Challenging conventional wisdom: the etiologic role of dopamine oxidative stress in Parkinson's disease. Mov. Disord. 2005, 20:271-282.
4. Niranjan R. The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson's disease: focus on astrocytes. Mol. Neurobiol. 2014, 49:28-38.
5. Shimoharada K., Inoue S., Nakahara M., Kanzaki N., Shimizu S., Kang D., Hamasaki N., Kinoshita S. Urine concentration of biopyrrins: a new marker for oxidative stress in vivo. Clin. Chem. 1998, 44:2554-2555.