-
1
-
-
81255188905
-
The lymphatic vasculature in disease
-
Alitalo K (2011) The lymphatic vasculature in disease. Nat Med 17: 1371-1380
-
(2011)
Nat Med
, vol.17
, pp. 1371-1380
-
-
Alitalo, K.1
-
2
-
-
84907010946
-
The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel
-
Aspelund A, Tammela T, Antila S, Nurmi H, Leppanen VM, Zarkada G, Stanczuk L, Francois M, Makinen T, Saharinen P et al (2014) The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel. J Clin Invest 124: 3975-3986
-
(2014)
J Clin Invest
, vol.124
, pp. 3975-3986
-
-
Aspelund, A.1
Tammela, T.2
Antila, S.3
Nurmi, H.4
Leppanen, V.M.5
Zarkada, G.6
Stanczuk, L.7
Francois, M.8
Makinen, T.9
Saharinen, P.10
-
3
-
-
84903129974
-
Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting
-
Astin JW, Haggerty MJ, Okuda KS, Le Guen L, Misa JP, Tromp A, Hogan BM, Crosier KE, Crosier PS (2014) Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting. Development 141: 2680-2690
-
(2014)
Development
, vol.141
, pp. 2680-2690
-
-
Astin, J.W.1
Haggerty, M.J.2
Okuda, K.S.3
Le Guen, L.4
Misa, J.P.5
Tromp, A.6
Hogan, B.M.7
Crosier, K.E.8
Crosier, P.S.9
-
4
-
-
13844273017
-
Vascular endothelial growth factor D is dispensable for development of the lymphatic system
-
Baldwin ME, Halford MM, Roufail S, Williams RA, Hibbs ML, Grail D, Kubo H, Stacker SA, Achen MG (2005) Vascular endothelial growth factor D is dispensable for development of the lymphatic system. Mol Cell Biol 25: 2441-2449
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2441-2449
-
-
Baldwin, M.E.1
Halford, M.M.2
Roufail, S.3
Williams, R.A.4
Hibbs, M.L.5
Grail, D.6
Kubo, H.7
Stacker, S.A.8
Achen, M.G.9
-
5
-
-
20144369085
-
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
-
Baluk P, Tammela T, Ator E, Lyubynska N, Achen MG, Hicklin DJ, Jeltsch M, Petrova TV, Pytowski B, Stacker SA et al (2005) Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest 115: 247-257
-
(2005)
J Clin Invest
, vol.115
, pp. 247-257
-
-
Baluk, P.1
Tammela, T.2
Ator, E.3
Lyubynska, N.4
Achen, M.G.5
Hicklin, D.J.6
Jeltsch, M.7
Petrova, T.V.8
Pytowski, B.9
Stacker, S.A.10
-
6
-
-
34547092416
-
Vascular endothelial growth factor-C stimulates the lymphatic pump by a VEGF receptor-3-dependent mechanism
-
Breslin JW, Gaudreault N, Watson KD, Reynoso R, Yuan SY, Wu MH (2007) Vascular endothelial growth factor-C stimulates the lymphatic pump by a VEGF receptor-3-dependent mechanism. Am J Physiol Heart Circ Physiol 293: H709-H718
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
, pp. H709-H718
-
-
Breslin, J.W.1
Gaudreault, N.2
Watson, K.D.3
Reynoso, R.4
Yuan, S.Y.5
Wu, M.H.6
-
7
-
-
58149100558
-
The lymphatic system in health and disease
-
Cueni LN, Detmar M (2008) The lymphatic system in health and disease. Lymphat Res Biol 6: 109-122
-
(2008)
Lymphat Res Biol
, vol.6
, pp. 109-122
-
-
Cueni, L.N.1
Detmar, M.2
-
8
-
-
77955271961
-
Lymphatic lipid transport: sewer or subway?
-
Dixon JB (2010) Lymphatic lipid transport: sewer or subway? Trends Endocrinol Metab 21: 480-487
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 480-487
-
-
Dixon, J.B.1
-
9
-
-
0032582502
-
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
-
Dumont DJ, Jussila L, Taipale J, Lymboussaki A, Mustonen T, Pajusola K, Breitman M, Alitalo K (1998) Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science 282: 946-949
-
(1998)
Science
, vol.282
, pp. 946-949
-
-
Dumont, D.J.1
Jussila, L.2
Taipale, J.3
Lymboussaki, A.4
Mustonen, T.5
Pajusola, K.6
Breitman, M.7
Alitalo, K.8
-
10
-
-
34548316976
-
Molecular basis for sunitinib efficacy and future clinical development
-
Faivre S, Demetri G, Sargent W, Raymond E (2007) Molecular basis for sunitinib efficacy and future clinical development. Nat Rev Drug Discov 6: 734-745
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 734-745
-
-
Faivre, S.1
Demetri, G.2
Sargent, W.3
Raymond, E.4
-
11
-
-
84880456245
-
Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis
-
Gogineni A, Caunt M, Crow A, Lee CV, Fuh G, van Bruggen N, Ye W, Weimer RM (2013) Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis. PLoS ONE 8: e68755
-
(2013)
PLoS ONE
, vol.8
, pp. e68755
-
-
Gogineni, A.1
Caunt, M.2
Crow, A.3
Lee, C.V.4
Fuh, G.5
van Bruggen, N.6
Ye, W.7
Weimer, R.M.8
-
12
-
-
47949083776
-
Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos
-
Haiko P, Makinen T, Keskitalo S, Taipale J, Karkkainen MJ, Baldwin ME, Stacker SA, Achen MG, Alitalo K (2008) Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos. Mol Cell Biol 28: 4843-4850
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4843-4850
-
-
Haiko, P.1
Makinen, T.2
Keskitalo, S.3
Taipale, J.4
Karkkainen, M.J.5
Baldwin, M.E.6
Stacker, S.A.7
Achen, M.G.8
Alitalo, K.9
-
13
-
-
49649083397
-
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
-
Heckman CA, Holopainen T, Wirzenius M, Keskitalo S, Jeltsch M, Yla-Herttuala S, Wedge SR, Jurgensmeier JM, Alitalo K (2008) The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis. Cancer Res 68: 4754-4762
-
(2008)
Cancer Res
, vol.68
, pp. 4754-4762
-
-
Heckman, C.A.1
Holopainen, T.2
Wirzenius, M.3
Keskitalo, S.4
Jeltsch, M.5
Yla-Herttuala, S.6
Wedge, S.R.7
Jurgensmeier, J.M.8
Alitalo, K.9
-
14
-
-
24044454409
-
Structural and mechanical architecture of the intestinal villi and crypts in the rat intestine: integrative reevaluation from ultrastructural analysis
-
Hosoyamada Y, Sakai T (2005) Structural and mechanical architecture of the intestinal villi and crypts in the rat intestine: integrative reevaluation from ultrastructural analysis. Anat Embryol 210: 1-12
-
(2005)
Anat Embryol
, vol.210
, pp. 1-12
-
-
Hosoyamada, Y.1
Sakai, T.2
-
15
-
-
34548561558
-
Mechanical components of rat intestinal villi as revealed by ultrastructural analysis with special reference to the axial smooth muscle cells in the villi
-
Hosoyamada Y, Sakai T (2007) Mechanical components of rat intestinal villi as revealed by ultrastructural analysis with special reference to the axial smooth muscle cells in the villi. Arch Histol Cytol 70: 107-116
-
(2007)
Arch Histol Cytol
, vol.70
, pp. 107-116
-
-
Hosoyamada, Y.1
Sakai, T.2
-
16
-
-
32944474182
-
VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
-
Kamba T, Tam BY, Hashizume H, Haskell A, Sennino B, Mancuso MR, Norberg SM, O'Brien SM, Davis RB, Gowen LC et al (2006) VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am J Physiol Heart Circ Physiol 290: H560-H576
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
, pp. H560-H576
-
-
Kamba, T.1
Tam, B.Y.2
Hashizume, H.3
Haskell, A.4
Sennino, B.5
Mancuso, M.R.6
Norberg, S.M.7
O'Brien, S.M.8
Davis, R.B.9
Gowen, L.C.10
-
17
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
-
Karkkainen MJ, Haiko P, Sainio K, Partanen J, Taipale J, Petrova TV, Jeltsch M, Jackson DG, Talikka M, Rauvala H et al (2004) Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol 5: 74-80
-
(2004)
Nat Immunol
, vol.5
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
Partanen, J.4
Taipale, J.5
Petrova, T.V.6
Jeltsch, M.7
Jackson, D.G.8
Talikka, M.9
Rauvala, H.10
-
18
-
-
0035940403
-
A model for gene therapy of human hereditary lymphedema
-
Karkkainen MJ, Saaristo A, Jussila L, Karila KA, Lawrence EC, Pajusola K, Bueler H, Eichmann A, Kauppinen R, Kettunen MI et al (2001) A model for gene therapy of human hereditary lymphedema. Proc Natl Acad Sci USA 98: 12677-12682
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12677-12682
-
-
Karkkainen, M.J.1
Saaristo, A.2
Jussila, L.3
Karila, K.A.4
Lawrence, E.C.5
Pajusola, K.6
Bueler, H.7
Eichmann, A.8
Kauppinen, R.9
Kettunen, M.I.10
-
19
-
-
34447560045
-
Lymphatic development in mouse small intestine
-
Kim KE, Sung HK, Koh GY (2007) Lymphatic development in mouse small intestine. Dev Dyn 236: 2020-2025
-
(2007)
Dev Dyn
, vol.236
, pp. 2020-2025
-
-
Kim, K.E.1
Sung, H.K.2
Koh, G.Y.3
-
20
-
-
84875981816
-
Getting out and about: the emergence and morphogenesis of the vertebrate lymphatic vasculature
-
Koltowska K, Betterman KL, Harvey NL, Hogan BM (2013) Getting out and about: the emergence and morphogenesis of the vertebrate lymphatic vasculature. Development 140: 1857-1870
-
(2013)
Development
, vol.140
, pp. 1857-1870
-
-
Koltowska, K.1
Betterman, K.L.2
Harvey, N.L.3
Hogan, B.M.4
-
21
-
-
0242624291
-
Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3
-
Makinen T, Veikkola T, Mustjoki S, Karpanen T, Catimel B, Nice EC, Wise L, Mercer A, Kowalski H, Kerjaschki D et al (2001) Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3. EMBO J 20: 4762-4773
-
(2001)
EMBO J
, vol.20
, pp. 4762-4773
-
-
Makinen, T.1
Veikkola, T.2
Mustjoki, S.3
Karpanen, T.4
Catimel, B.5
Nice, E.C.6
Wise, L.7
Mercer, A.8
Kowalski, H.9
Kerjaschki, D.10
-
22
-
-
0014086975
-
The effect of a non-ionic detergent (Triton WR 1339) on the removal of triglyceride fatty acids from the blood of the rat
-
Otway S, Robinson DS (1967) The effect of a non-ionic detergent (Triton WR 1339) on the removal of triglyceride fatty acids from the blood of the rat. J Physiol 190: 309-319
-
(1967)
J Physiol
, vol.190
, pp. 309-319
-
-
Otway, S.1
Robinson, D.S.2
-
23
-
-
0036137724
-
Vascular endothelial growth factors C and D and their VEGFR-2 and 3 receptors in blood and lymphatic vessels in healthy and arthritic synovium
-
Paavonen K, Mandelin J, Partanen T, Jussila L, Li TF, Ristimaki A, Alitalo K, Konttinen YT (2002) Vascular endothelial growth factors C and D and their VEGFR-2 and 3 receptors in blood and lymphatic vessels in healthy and arthritic synovium. J Rheumatol 29: 39-45
-
(2002)
J Rheumatol
, vol.29
, pp. 39-45
-
-
Paavonen, K.1
Mandelin, J.2
Partanen, T.3
Jussila, L.4
Li, T.F.5
Ristimaki, A.6
Alitalo, K.7
Konttinen, Y.T.8
-
24
-
-
84880333521
-
Vascular endothelial growth factor-d modulates caliber and function of initial lymphatics in the dermis
-
Paquet-Fifield S, Levy SM, Sato T, Shayan R, Karnezis T, Davydova N, Nowell CJ, Roufail S, Ma GZ, Zhang YF et al (2013) Vascular endothelial growth factor-d modulates caliber and function of initial lymphatics in the dermis. J Invest Dermatol 133: 2074-2084
-
(2013)
J Invest Dermatol
, vol.133
, pp. 2074-2084
-
-
Paquet-Fifield, S.1
Levy, S.M.2
Sato, T.3
Shayan, R.4
Karnezis, T.5
Davydova, N.6
Nowell, C.J.7
Roufail, S.8
Ma, G.Z.9
Zhang, Y.F.10
-
25
-
-
0033814892
-
VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
-
Partanen TA, Arola J, Saaristo A, Jussila L, Ora A, Miettinen M, Stacker SA, Achen MG, Alitalo K (2000) VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J 14: 2087-2096
-
(2000)
FASEB J
, vol.14
, pp. 2087-2096
-
-
Partanen, T.A.1
Arola, J.2
Saaristo, A.3
Jussila, L.4
Ora, A.5
Miettinen, M.6
Stacker, S.A.7
Achen, M.G.8
Alitalo, K.9
-
26
-
-
0037714018
-
VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses
-
Rissanen TT, Markkanen JE, Gruchala M, Heikura T, Puranen A, Kettunen MI, Kholova I, Kauppinen RA, Achen MG, Stacker SA et al (2003) VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses. Circ Res 92: 1098-1106
-
(2003)
Circ Res
, vol.92
, pp. 1098-1106
-
-
Rissanen, T.T.1
Markkanen, J.E.2
Gruchala, M.3
Heikura, T.4
Puranen, A.5
Kettunen, M.I.6
Kholova, I.7
Kauppinen, R.A.8
Achen, M.G.9
Stacker, S.A.10
-
27
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
-
Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu XF, Breitman ML, Schuh AC (1995) Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376: 62-66
-
(1995)
Nature
, vol.376
, pp. 62-66
-
-
Shalaby, F.1
Rossant, J.2
Yamaguchi, T.P.3
Gertsenstein, M.4
Wu, X.F.5
Breitman, M.L.6
Schuh, A.C.7
-
28
-
-
17744396472
-
Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice
-
Veikkola T, Jussila L, Makinen T, Karpanen T, Jeltsch M, Petrova TV, Kubo H, Thurston G, McDonald DM, Achen MG et al (2001) Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice. EMBO J 20: 1223-1231
-
(2001)
EMBO J
, vol.20
, pp. 1223-1231
-
-
Veikkola, T.1
Jussila, L.2
Makinen, T.3
Karpanen, T.4
Jeltsch, M.5
Petrova, T.V.6
Kubo, H.7
Thurston, G.8
McDonald, D.M.9
Achen, M.G.10
-
29
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T (2007) Restoration of p53 function leads to tumour regression in vivo. Nature 445: 661-665
-
(2007)
Nature
, vol.445
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
Tuveson, D.A.4
Grimm, J.5
Lintault, L.6
Newman, J.7
Reczek, E.E.8
Weissleder, R.9
Jacks, T.10
|