Solid Phase Extraction as an Innovative Separation Method for Measuring Free and Entrapped Drug in Lipid Nanoparticles

Pharmaceutical Research

Volumn 32, Issue 12, 2015, Pages 3999-4009

  Guillot, Alexis ^a,b,f   Couffin, Anne Claude ^c,d   Sejean, Xavier ^c,d   Navarro, Fabrice ^c,d   Limberger, Markus ^a,g   Lehr, Claus Michael ^b,e  

^a PHAST GmbH   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIV GRENOBLE ALPES   (France)

^d CEA LETI   (France)

^e SAARLAND UNIVERSITY   (Germany)

^f Eurofins Medinet Inc   (Germany)

^g NONE   (Germany)

Author keywords

cyclosporine; lipid nanoemulsion; nanoparticles; separation techniques; solid phase extraction

Indexed keywords

BUFFER; CYCLOSPORIN A; LIPID; NANOPARTICLE; CYCLOSPORIN; DRUG CARRIER; IMMUNOSUPPRESSIVE AGENT;

ACCURACY; ARTICLE; DYNAMIC LIGHT SCATTERING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGHT SCATTERING; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; CHEMISTRY; DRUG STABILITY; ISOLATION AND PURIFICATION; PARTICLE SIZE; PROCEDURES;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOSPORINE; DRUG CARRIERS; DRUG STABILITY; IMMUNOSUPPRESSIVE AGENTS; LIPIDS; NANOPARTICLES; PARTICLE SIZE; SOLID PHASE EXTRACTION;

EID: 84946473985     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-015-1761-8     Document Type: Article

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