A screenable in vivo assay for mitochondrial modulators using transgenic bioluminescent Caenorhabditis elegans

Journal of Visualized Experiments

Volumn 2015, Issue 104, 2015, Pages

  Lagido, Cristina ^a   McLaggan, Debbie ^a   Glover, L Anne ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Bioluminescence; Biosensors; Caenorhabditis elegans; Cellular ATP; Complex I; Drug screening; Electron transport chain; Firefly luciferase; Issue 104; Mitochondria; Model organisms; Molecular biology

Indexed keywords

ENZYME INHIBITOR; FIREFLY LUCIFERASE; OXALOACETIC ACID; PARAQUAT; ROTENONE; UNCOUPLING PROTEIN;

ANIMAL; ANTAGONISTS AND INHIBITORS; CAENORHABDITIS ELEGANS; DRUG EFFECTS; LUMINESCENCE; MITOCHONDRION; PHYSIOLOGY; PRECLINICAL STUDY; PROCEDURES; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; LUCIFERASES, FIREFLY; LUMINESCENT MEASUREMENTS; MITOCHONDRIA; OXALOACETIC ACID; PARAQUAT; ROTENONE; UNCOUPLING AGENTS;

EID: 84946423332     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/53083     Document Type: Article

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