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Volumn 59, Issue 11, 2015, Pages 7044-7053
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Structure-activity relationship of the aminomethylcyclines and the discovery of omadacycline
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Author keywords
[No Author keywords available]
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Indexed keywords
AMINOMETHYLCYCLINE DERIVATIVE;
CIPROFLOXACIN;
METHYL GROUP;
MINOCYCLINE;
OMADACYCLINE;
TETRACYCLINE DERIVATIVE;
TIGECYCLINE;
UNCLASSIFIED DRUG;
VANCOMYCIN;
ANTIINFECTIVE AGENT;
ALKYLATION;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTIBACTERIAL ACTIVITY;
ANTIBIOTIC RESISTANCE;
ARTICLE;
CHO CELL LINE;
COLONY FORMING UNIT;
CONTROLLED STUDY;
DRUG BIOAVAILABILITY;
DRUG EFFICACY;
DRUG SAFETY;
DRUG SYNTHESIS;
ENTEROCOCCUS FAECALIS;
FEMALE;
HAPLORHINI;
IN VITRO STUDY;
LIPOPHILICITY;
MINIMUM INHIBITORY CONCENTRATION;
MOUSE;
NONHUMAN;
PLASMA PROTEIN BINDING;
PNEUMOCOCCAL INFECTION;
PRIORITY JOURNAL;
STAPHYLOCOCCUS AUREUS;
STREPTOCOCCUS PNEUMONIAE;
STRUCTURE ACTIVITY RELATION;
VANCOMYCIN RESISTANT ENTEROCOCCUS;
WOUND INFECTION;
DRUG EFFECTS;
GRAM POSITIVE BACTERIUM;
METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;
MICROBIAL SENSITIVITY TEST;
ANTI-BACTERIAL AGENTS;
ENTEROCOCCUS FAECALIS;
GRAM-POSITIVE BACTERIA;
METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS;
MICROBIAL SENSITIVITY TESTS;
MINOCYCLINE;
STAPHYLOCOCCUS AUREUS;
STREPTOCOCCUS PNEUMONIAE;
STRUCTURE-ACTIVITY RELATIONSHIP;
TETRACYCLINES;
VANCOMYCIN-RESISTANT ENTEROCOCCI;
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EID: 84946200475
PISSN: 00664804
EISSN: 10986596
Source Type: Journal
DOI: 10.1128/AAC.01536-15 Document Type: Article |
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Times cited : (115)
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References (12)
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