Regulation of inflammatory biomarkers by intravenous methylprednisolone in pediatric ARDS patients: Results from a double-blind, placebo-controlled randomized pilot trial

Cytokine

Volumn 77, Issue , 2016, Pages 63-71

  Schwingshackl, Andreas ^a   Kimura, Dai ^b   Rovnaghi, Cynthia R ^b   Saravia, Jordy S ^b   Cormier, Stephania A ^b   Teng, Bin ^b   West, Alina N ^b   Meduri, Umberto G ^b   Anand, Kanwaljeet J S ^c  

^a MATTEL CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

ARDS; Chemokines; Cytokines; Glucocorticoids; Inflammation; Lung injury; Mediators; Pediatrics; Steroids

Indexed keywords

ALPHA INTERFERON; BIOLOGICAL MARKER; EOTAXIN; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; INTERLEUKIN 9; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; METHYLPREDNISOLONE; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; PLACEBO; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; C REACTIVE PROTEIN; CYTOKINE; GLUCOCORTICOID;

ADOLESCENT; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; ARTIFICIAL VENTILATION; BLOOD CLOTTING; CHILD; CLINICAL ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; HUMAN; HUMAN CELL; INFANT; INFLAMMATION; LEUKOCYTE COUNT; LOADING DRUG DOSE; PILOT STUDY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; TERTIARY CARE CENTER; THROMBOCYTE COUNT; ACUTE DISEASE; BLOOD; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; LUNG DISEASES; MALE; METABOLISM; NEWBORN; PRESCHOOL CHILD; PROGNOSIS; REGRESSION ANALYSIS; TREATMENT OUTCOME;

ACUTE DISEASE; ADOLESCENT; BIOMARKERS; C-REACTIVE PROTEIN; CHILD; CHILD, PRESCHOOL; CYTOKINES; DOUBLE-BLIND METHOD; FEMALE; GLUCOCORTICOIDS; HUMANS; INFANT; INFANT, NEWBORN; INFLAMMATION MEDIATORS; INFUSIONS, INTRAVENOUS; LUNG DISEASES; MALE; METHYLPREDNISOLONE; PILOT PROJECTS; PROGNOSIS; REGRESSION ANALYSIS; TREATMENT OUTCOME;

EID: 84946076407     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2015.10.007     Document Type: Article

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