Indolic uremic solutes enhance procoagulant activity of red blood cells through phosphatidylserine exposure and microparticle release

Toxins

Volumn 7, Issue 11, 2015, Pages 4390-4403

  Gao, Chunyan ^a   Ji, Shuting ^a   Dong, Weijun ^a   Qi, Yushan ^a   Song, Wen ^a   Cui, Debin ^a   Shi, Jialan ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Indole 3 acetic acid; Indoxyl sulfate; Microparticle; Phosphatidylserine; Procoagulant; Red blood cell

Indexed keywords

INDICAN; INDOLEACETIC ACID; LACTADHERIN; PHOSPHATIDYLSERINE; PROCOAGULANT; ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10A; CALCIUM; INDOLE DERIVATIVE; INDOLEACETIC ACID DERIVATIVE; THROMBOPLASTIN;

ADULT; ARTICLE; BLOOD CLOTTING TIME; CALCIUM CELL LEVEL; CONTROLLED STUDY; ERYTHROCYTE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MEMBRANE MICROPARTICLE; NORMAL HUMAN; PROTEIN PURIFICATION; UREMIA; ANTAGONISTS AND INHIBITORS; BLOOD; BLOOD CLOTTING; CYTOSOL; DRUG EFFECTS; FEMALE; MALE; METABOLISM; THROMBOSIS; URINE; YOUNG ADULT;

ANTICOAGULANTS; BLOOD COAGULATION; CALCIUM; CELL-DERIVED MICROPARTICLES; CYTOSOL; ERYTHROCYTES; FACTOR XA; FEMALE; FLOW CYTOMETRY; HUMANS; INDICAN; INDOLEACETIC ACIDS; INDOLES; MALE; PHOSPHATIDYLSERINES; THROMBOPLASTIN; THROMBOSIS; UREMIA; YOUNG ADULT;

EID: 84946062774     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins7114390     Document Type: Article

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