Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancer

Oncotarget

Volumn 6, Issue 32, 2015, Pages 33470-33485

  Jia, Yan ^a,b   Cao, Baoping ^a,c   Yang, Yunsheng ^a   Linghu, Enqiang ^a   Zhan, Qimin ^d   Lu, Youyong ^e   Yu, Yingyan ^f   Herman, James G ^g   Guo, Mingzhou ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c NANKAI UNIVERSITY   (China)

^d CANCER HOSPITAL   (China)

^e PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

^f SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^g UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

DNA methylation; Gastric cancer; NKD1; NKD2; SOX18

Indexed keywords

DNA; DOCETAXEL; GELATINASE A; GELATINASE B; MATRILYSIN; MEMBRANE PROTEIN; PROTEIN NKD1; PROTEIN NKD2; TRANSCRIPTION FACTOR SOX18; UNCLASSIFIED DRUG; CARRIER PROTEIN; NKD2 PROTEIN, HUMAN; SOX18 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOASSAY; CANCER STAGING; CARCINOGENESIS; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DISTANT METASTASIS; DNA METHYLATION; DRUG SENSITIVITY; FEMALE; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; GASTRIC CANCER CELL LINE; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOUSE; NKD1 GENE; NKD2 GENE; NONHUMAN; PRIMARY TUMOR; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INTERACTION; STOMACH CANCER; TRANSWELL ASSAY; TUMOR INVASION; TUMOR XENOGRAFT; UPREGULATION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; GENE SILENCING; GENETICS; METABOLISM; METASTASIS; MIDDLE AGED; PROGNOSIS; STOMACH TUMOR; TUMOR CELL LINE;

CARRIER PROTEINS; CELL LINE, TUMOR; DNA METHYLATION; FEMALE; GENE SILENCING; HUMANS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PROGNOSIS; PROMOTER REGIONS, GENETIC; SOXF TRANSCRIPTION FACTORS; STOMACH NEOPLASMS; UP-REGULATION;

EID: 84946041011     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5272     Document Type: Article

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