Effects of structured exercise and pharmacotherapy vs. pharmacotherapy for adults with depressive symptoms: A randomized clinical trial

Journal of Psychiatric Research

Volumn 71, Issue , 2015, Pages 48-55

  Carneiro, Lara S F ^a   Fonseca, António Manuel ^b   Vieira Coelho, Maria Augusta ^c,d   Mota, Maria Paula ^a   Vasconcelos Raposo, José ^a  

^a UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c Universidade do Porto   (Portugal)

^d University of Porto   (Portugal)

Author keywords

Aerobic exercise; Depression; Major depressive disorder; Women

Indexed keywords

DIAZEPAM; ESCITALOPRAM; ESTAZOLAM; FLUOXETINE; LORAZEPAM; PAROXETINE; SERTRALINE; ANTIDEPRESSANT AGENT;

ACHIEVEMENT; ADULT; AEROBIC EXERCISE; ANTHROPOMETRIC PARAMETERS; ANXIETY; ARTICLE; ATTENTION; BECK DEPRESSION INVENTORY; BEHAVIOR CHANGE; BODY MASS; BODY WEIGHT; CLINICAL ARTICLE; CONTROL GROUP; CONTROLLED STUDY; DEPRESSION; DEPRESSION ANXIETY STRESS SCALE; FAT MASS; FEMALE; FITNESS; HUMAN; MIDDLE AGED; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SELF ESTEEM; SYMPTOMATOLOGY; WAIST CIRCUMFERENCE; DEPRESSIVE DISORDER; KINESIOTHERAPY; MULTIMODALITY CANCER THERAPY; PATIENT CARE; PROCEDURES; SELF CONCEPT; TREATMENT OUTCOME;

ANTIDEPRESSIVE AGENTS; BODY MASS INDEX; COMBINED MODALITY THERAPY; DEPRESSIVE DISORDER; EXERCISE THERAPY; FEMALE; HUMANS; MIDDLE AGED; PATIENT CARE TEAM; SELF CONCEPT; TREATMENT OUTCOME; WAIST CIRCUMFERENCE;

EID: 84945973543     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2015.09.007     Document Type: Article

References (53)

1. American Psychiatric Association Practice Guideline for the Treatment of Patients with Major Depressive Disorder 2010, third ed.
2. Batterham A.M., Hopkins W.G. Making meaningful inferences about magnitudes. Int. J. Sports Physiol. Perform. 2006, 1:50-57.
3. Blumenthal J.A., Babyak M.A., Doraiswamy P.M., Watkins L., Hoffman B.M., Barbour K.A., et al. Exercise and pharmacotherapy in the treatment of major depressive disorder. Psychosom. Med. 2007, 69:587-596.
4. Bolton M.A., Lobben I., Stern T.A. The impact of body image on patient care. Prim. Care Companion J. Clin. Psychiatry 2010, 12:2.
5. Brenes G.A., Williamson J.D., Messier S.P., Rejeski W.J., Pahor M., Ip E., et al. Treatment of minor depression in older adults: a pilot study comparing sertraline and exercise. Aging Ment. Health 2007, 11:61-68.
6. Brown W.J., Ford J.H., Burton N.W., Marshall A.L., Dobson A.J. Prospective study of physical activity and depressive symptoms in middle-aged women. Am. J. Prev. Med. 2005, 29:265-272.
7. Button K.S., Ioannidis J.P., Mokrysz C., Nosek B.A., Flint J., Robinson E.S., et al. Power failure: why small sample size undermines the reliability of neuroscience. Nat. Rev. Neurosci. 2013, 14:365-376.
8. Callaghan P., Khalil E., Morres I., Carter T. Pragmatic randomised controlled trial of preferred intensity exercise in women living with depression. BMC Public Health 2011, 11:465.
9. Campos R.C., Gonçalves B. The portuguese version of the beck depression inventory-II (BDI-II): preliminary psychometric data with two nonclinical samples. Eur. J. Psychol. Assess. 2011, 27:258-264.
10. Chu I.H., Buckworth J., Kirby T.E., Emery C.F. Effect of exercise intensity on depressive symptoms in women. Ment. Health Phys. Act. 2009, 2:37-43.
11. Cohen J. Statistical Power Analysis for the Behavioral Sciences 1988, Lawrence Erlbaum Associates, Hillsdale, NJ. second ed.
12. Cooney G.M., Dwan K., Greig C.A., Lawlor D.A., Rimer J., Waugh F.R., et al. Exercise for depression. Cochrane Database Syst. Rev. 2013, 9:CD004366.
13. Craft L.L., Freund K.M., Culpepper L., Perna F.M. Intervention study of exercise for depressive symptoms in women. J. Womens Health 2007, 16:1499-1509.
14. Craft L.L. Exercise and clinical depression: examining two psychological mechanisms. Psychol. Sport Exerc. 2005, 6:151-171.
15. Cumming G. The New Statistics: Estimation for Better Research 2013, [cited 2015 Jan 19]. Available from:. http://www.thenewstatistics.com.
16. Cumming G. The new statistics: why and how. Psychol. Sci. 2013, 25:1-21.
17. Daley A., Jolly K. Exercise to treat depression. BMJ 2012, 344:e3181.
18. Dowlati Y., Herrmann N., Swardfager W., Liu H., Sham L., Reim E.K., et al. A meta-analysis of cytokines in major depression. Biol. Psychiatry 2010, 67:446-457.
19. Dunn A.L., Trivedi M.H., Kampert J.B., Clark C.G., Chambliss H.O. Exercise treatment for depression: efficacy and dose response. Am. J. Prev. Med. 2005, 28:1-8.
20. Fabricatore A.N., Wadden T.A., Higginbotham A.J., Faulconbridge L.F., Nguyen A.M., Heymsfield S.B., et al. Intentional weight loss and changes in symptoms of depression: a systematic review and meta-analysis. Int. J. Obes. 2011, 35:1363-1376.
21. Faulkner C., Fidler F., Cumming G. The value of RCT evidence depends on the quality of statistical analysis. Behav. Res. Ther. 2008, 46:270-281.
22. Gleeson M., Bishop N.C., Stensel D.J., Lindley M.R., Mastana S.S., Nimmo M.A. The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease. Nat. Rev. Immunol. 2011, 11:607-615.
23. Greer T.L., Trivedi M.H. Exercise in the treatment of depression. Curr. Psychiatry Rep. 2009, 11:466-472.
24. Heyman E., Gamelin F.X., Goekint M., Piscitelli F., Roelands B., Leclair E., et al. Intense exercise increases circulating endocannabinoid and BDNF levels in humans-possible implications for reward and depression. Psychoneuroendocrinology 2012, 37:844-851.
25. Hopkins W.G. Linear models and effect magnitudes for research, clinical and practical applications. Sport Sci. 2010, 14:49-57.
26. Hopkins W.G., Marshall S.W., Batterham A.M., Hanin J. Progressive statistics for studies in sports medicine and exercise science. Med. Sci. Sports Exerc. 2009, 41:3-12.
27. Kerse N., Hayman K.J., Moyes S.A., Peri K., Robinson E., Dowell A., et al. Home-based activity program for older people with depressive symptoms: DeLLITE-a randomized controlled trial. Ann. Fam. Med. 2010, 8:214-223.
28. Kessler R.C. Epidemiology of women and depression. J. Affect Disord. 2003, 74:5-13.
29. Knapen J., Vancampfort D., Morien Y., Marchal Y. Exercise therapy improves both mental and physical health in patients with major depression. Disabil. Rehabil. 2014, 1-6.
30. Kohut M.L., McCann D.A., Russell D.W., Konopka D.N., Cunnick J.E., Franke W.D., et al. Aerobic exercise, but not flexibility/resistance exercise, reduces serum IL-18, CRP, and IL-6 independent of beta-blockers, BMI, and psychosocial factors in older adults. Brain Behav. Immun. 2006, 20:201-209.
31. Krogh J., Nordentoft M., Sterne J.A., Lawlor D.A. The effect of exercise in clinically depressed adults: systematic review and meta-analysis of randomized controlled trials. J. Clin. Psychiatry 2011, 72:529-538.
32. Krogh J., Videbech P., Thomsen C., Gluud C., Nordentoft M. DEMO-II trial. Aerobic exercise versus stretching exercise in patients with major depression-A randomised clinical trial. PLoS One 2012, 7:e48316.
33. Kubryak O.V., Umriukhin A.E., Emeljanova I.N., Antipova O.S., Guseva A.L., Pertsov S.S., et al. Increased beta-endorphin level in blood plasma as an indicator of positive response to depression treatment. Bull. Exp. Biol. Med. 2012, 153:758-760.
34. Lepine J.P., Briley M. The increasing burden of depression. Neuropsychiatr. Dis. Treat. New 2011, 7:3-7.
35. Leppamaki S., Partonen T., Lonnqvist J. Bright-light exposure combined with physical exercise elevates mood. J. Affect Disord. 2002, 72:139-144.
36. Mota-Pereira J., Silverio J., Carvalho S., Ribeiro J.C., Fonte D., Ramos J. Moderate exercise improves depression parameters in treatment-resistant patients with major depressive disorder. J. Psychiatr. Res. 2011, 45:1005-1011.
37. National Institute for Health & Clinical Excellence Depression: the NICE Guideline on the Treatment and Management of Depression in Adults 2009, updated ed.
38. Parker G. Beyond major depression. Psychol. Med. 2005, 35:467-474.
39. Rethorst C.D., Wipfli B.M., Landers D.M. The antidepressive effects of exercise: a meta-analysis of randomized trials. Sports Med. 2009, 39:491-511.
40. Rimer J., Dwan K., Lawlor D.A., Greig C.A., McMurdo M., Morley W., et al. Exercise for depression. Cochrane Database Syst. Rev. 2012, 7:CD004366.
41. Rosenbaum S., Tiedemann A., Sherrington C., Curtis J., Ward P.B. Physical activity interventions for people with mental illness: a systematic review and meta-analysis. J. Clin. Psychiatry 2014, 75:964-974.
42. Salsali M., Silverstone P.H. Low self-esteem and psychiatric patients: part II - the relationship between self-esteem and demographic factors and psychosocial stressors in psychiatric patients. Ann. Gen. Hosp. Psychiatry 2003, 2:3.
43. Schuch F.B., Fleck M.P.D.A. Is exercise an efficacious treatment for depression? A comment upon recent negative findings. Front. Psychiatry 2013, 4:20.
44. Schuch F.B., Vasconcelos-Moreno M.P., Borowsky C., Fleck M.P. Exercise and severe depression: preliminary results of an add-on study. J. Affect Disord. 2011, 133:615-618.
45. Shahidi M., Mojtahed A., Modabbernia A., Mojtahed M., Shafiabady A., Delavar A., et al. Laughter yoga versus group exercise program in elderly depressed women: a randomized controlled trial. Int. J. Geriatr. Psychiatry 2011, 26:322-327.
46. Silveira H., Moraes H., Oliveira N., Coutinho E.S., Laks J., Deslandes A. Physical exercise and clinically depressed patients: a systematic review and meta-analysis. Neuropsychobiology 2013, 67:61-68.
47. Silverstone P.H., Salsali M. Low self-esteem and psychiatric patients: part I - the relationship between low self-esteem and psychiatric diagnosis. Ann. Gen. Hosp. Psychiatry 2003, 2:2.
48. Singh N.A., Stravinos T.M., Scarbek Y., Galambos G., Liber C., Singh M.A.F. A randomized controlled trial of high versus low intensity weight training versus general practitioner care for clinical depression in older adults. J. Gerontol. A Biol. Sci. Med. Sci. 2005, 60:768-776.
49. Sousa e Silva T., Longui C.A., Rocha M.N., Faria C.D., Melo M.R., Faria T.G., et al. Prolonged physical training decreases mRNA levels of glucocorticoid receptor and inflammatory genes. Horm. Res. Paediatr. 2010, 74:6-14.
50. Teychenne M., York R. Physical activity, sedentary behavior, and postnatal depressive symptoms: a review. Am. J. Prev. Med. 2013, 45:217-227.
51. Trivedi M.H., Greer T.L., Church T.S., Carmody T.J., Grannemann B.D., Galper D.I., et al. Exercise as an augmentation treatment for nonremitted major depressive disorder: a randomized, parallel dose comparison. J. Clin. Psychiatry 2011, 72:677-684.
52. Vasconcelos-Raposo J., Fernandes H.M., Teixeira C.M. Factor structure and reliability of the depression, anxiety and stress scales in a large Portuguese community sample. Span. J. Psychol. 2013, 16:E10.
53. Vasconcelos-Raposo J., Fernandes M., Teixeira C., Bertelli R. Factorial validity and invariance of the Rosenberg self-esteem scale among Portuguese youngsters. Soc. Indic. Res. 2012, 105:483-498.