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Volumn 5, Issue 10, 2015, Pages

Patients who discontinued statin treatment: A protocol for cohort study using primary care data

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN; NON PRESCRIPTION DRUG;

EID: 84945911272     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2015-008701     Document Type: Article
Times cited : (5)

References (45)
  • 2
    • 47149088261 scopus 로고    scopus 로고
    • Predicting cardiovascular risk in England and Wales: Prospective derivation and validation of QRISK2
    • Hippisley-Cox J, Coupland C, Vinogradova Y, et al. Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2. BMJ 2008;336:1475-82.
    • (2008) BMJ , vol.336 , pp. 1475-1482
    • Hippisley-Cox, J.1    Coupland, C.2    Vinogradova, Y.3
  • 3
    • 84899666419 scopus 로고    scopus 로고
    • Lipid modification: Cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease
    • London: NICE
    • National Institute for Health and Care Excellence. Lipid modification: cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease. Clinical guideline 67. London: NICE, 2008.
    • (2008) Clinical Guideline 67
    • National Institute for Health and Care Excellence1
  • 4
    • 84864832599 scopus 로고    scopus 로고
    • The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: Meta-analysis of individual data from 27 randomised trials
    • Mihaylova, B Emberson, J Blackwell, L, et al. Cholesterol Treatment Trialists Collaborators. The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet 2012;380:581-90.
    • (2012) Lancet , vol.380 , pp. 581-590
    • Mihaylova, B.1    Emberson, J.2    Blackwell, L.3
  • 5
    • 84899666419 scopus 로고    scopus 로고
    • Lipid modification: Cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease
    • London: NICE
    • National Institute for Health and Care Excellence. Lipid modification: cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease. Clinical guideline 181. London: NICE, 2014.
    • (2014) Clinical Guideline 181
    • National Institute for Health and Care Excellence1
  • 6
    • 84902576469 scopus 로고    scopus 로고
    • 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • Stone NJ, Robinson JG, Lichtenstein AH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014;63(25, Part B):2889-934.
    • (2014) J Am Coll Cardiol , vol.63 , Issue.25 , pp. 2889-2934
    • Stone, N.J.1    Robinson, J.G.2    Lichtenstein, A.H.3
  • 7
    • 0035020638 scopus 로고    scopus 로고
    • Poor adherence with hypolipidemic drugs: A lost opportunity
    • Tsuyuki RT, Bungard TJ. Poor adherence with hypolipidemic drugs: a lost opportunity. Pharmacotherapy 2001;21:576-82.
    • (2001) Pharmacotherapy , vol.21 , pp. 576-582
    • Tsuyuki, R.T.1    Bungard, T.J.2
  • 8
    • 67649523031 scopus 로고    scopus 로고
    • Medication adherence: Its importance in cardiovascular outcomes
    • Ho PM, Bryson CL, Rumsfeld JS. Medication adherence: its importance in cardiovascular outcomes. Circulation 2009;119:3028-35.
    • (2009) Circulation , vol.119 , pp. 3028-3035
    • Ho, P.M.1    Bryson, C.L.2    Rumsfeld, J.S.3
  • 9
    • 80053353330 scopus 로고    scopus 로고
    • Novel mechanistic and clinical implications concerning the safety of statin discontinuation
    • Jasinska-Stroschein M, Owczarek J, Wejman I, et al. Novel mechanistic and clinical implications concerning the safety of statin discontinuation. Pharmacol Rep 2011;63:867-79.
    • (2011) Pharmacol Rep , vol.63 , pp. 867-879
    • Jasinska-Stroschein, M.1    Owczarek, J.2    Wejman, I.3
  • 10
    • 0037177167 scopus 로고    scopus 로고
    • Withdrawal of statins increases event rates in patients with acute coronary syndromes
    • Heeschen C, Hamm CW, Laufs U, et al. Withdrawal of statins increases event rates in patients with acute coronary syndromes. Circulation 2002;105:1446-52.
    • (2002) Circulation , vol.105 , pp. 1446-1452
    • Heeschen, C.1    Hamm, C.W.2    Laufs, U.3
  • 11
    • 34848915855 scopus 로고    scopus 로고
    • Discontinuation of statin therapy and clinical outcome after ischemic stroke
    • Colivicchi F, Bassi A, Santini M, et al. Discontinuation of statin therapy and clinical outcome after ischemic stroke. Stroke 2007;38:2652-7.
    • (2007) Stroke , vol.38 , pp. 2652-2657
    • Colivicchi, F.1    Bassi, A.2    Santini, M.3
  • 12
    • 68749105920 scopus 로고    scopus 로고
    • Withdrawal of statins and risk of subarachnoid hemorrhage
    • Risselada R, Straatman H, Van Kooten F, et al. Withdrawal of statins and risk of subarachnoid hemorrhage. Stroke 2009;40:2887-92.
    • (2009) Stroke , vol.40 , pp. 2887-2892
    • Risselada, R.1    Straatman, H.2    Van Kooten, F.3
  • 13
    • 6444234849 scopus 로고    scopus 로고
    • There is no evidence for an increase in acute coronary syndromes after short-term abrupt discontinuation of statins in stable cardiac patients
    • McGowan MP, Treating to New Target (TNT) Study Group. There is no evidence for an increase in acute coronary syndromes after short-term abrupt discontinuation of statins in stable cardiac patients. Circulation 2004;110:2333-5.
    • (2004) Circulation , vol.110 , pp. 2333-2335
    • McGowan, M.P.1
  • 14
    • 84904497873 scopus 로고    scopus 로고
    • Non-cardiovascular effects associated with statins
    • Desai CS, Martin SS, Blumenthal RS. Non-cardiovascular effects associated with statins. BMJ 2014;349:g3743.
    • (2014) BMJ , vol.349 , pp. g3743
    • Desai, C.S.1    Martin, S.S.2    Blumenthal, R.S.3
  • 15
    • 84939969799 scopus 로고    scopus 로고
    • Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: A 6 year follow-up study of the METSIM cohort
    • Cederberg H, Stančáková A, Yaluri N, et al. Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort. Diabetologia 2015;58:1109-17.
    • (2015) Diabetologia , vol.58 , pp. 1109-1117
    • Cederberg, H.1    Stančáková, A.2    Yaluri, N.3
  • 16
    • 84904086869 scopus 로고    scopus 로고
    • Statins and the risk of type 2 diabetes mellitus: Cohort study using the UK clinical practice research datalink
    • Macedo A, Douglas I, Smeeth L, et al. Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice research datalink. BMC Cardiovasc Disord 2014;14:85.
    • (2014) BMC Cardiovasc Disord , vol.14 , pp. 85
    • Macedo, A.1    Douglas, I.2    Smeeth, L.3
  • 17
    • 84862907917 scopus 로고    scopus 로고
    • Statin use and musculoskeletal pain among adults with and without arthritis
    • Buettner C, Rippberger MJ, Smith JK, et al. Statin use and musculoskeletal pain among adults with and without arthritis. Am J Med 2012;125:176-82.
    • (2012) Am J Med , vol.125 , pp. 176-182
    • Buettner, C.1    Rippberger, M.J.2    Smith, J.K.3
  • 18
    • 32444444724 scopus 로고    scopus 로고
    • Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients - The PRIMO study
    • Bruckert E, Hayem G, Dejager S, et al. Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients - the PRIMO study. Cardiovasc Drugs Ther 2005;19:403-14.
    • (2005) Cardiovasc Drugs Ther , vol.19 , pp. 403-414
    • Bruckert, E.1    Hayem, G.2    Dejager, S.3
  • 19
    • 77954179995 scopus 로고    scopus 로고
    • Statins and all-cause mortality in high-risk primary prevention: A meta-analysis of 11 randomized controlled trials involving 65 229 participants
    • Ray KK, Seshasai S, Erqou S, et al. Statins and all-cause mortality in high-risk primary prevention: A meta-analysis of 11 randomized controlled trials involving 65 229 participants. Arch Intern Med 2010;170:1024-31.
    • (2010) Arch Intern Med , vol.170 , pp. 1024-1031
    • Ray, K.K.1    Seshasai, S.2    Erqou, S.3
  • 20
    • 84886608030 scopus 로고    scopus 로고
    • Should people at low risk of cardiovascular disease take a statin?
    • Abramson JD, Rosenberg HG, Jewell N, et al. Should people at low risk of cardiovascular disease take a statin? BMJ 2013;347:f6123.
    • (2013) BMJ , vol.347 , pp. f6123
    • Abramson, J.D.1    Rosenberg, H.G.2    Jewell, N.3
  • 21
    • 65449149106 scopus 로고    scopus 로고
    • Statin adherence and risk of accidents: A cautionary tale
    • Dormuth CR, Patrick AR, Shrank WH, et al. Statin adherence and risk of accidents: a cautionary tale. Circulation 2009;119:2051-7.
    • (2009) Circulation , vol.119 , pp. 2051-2057
    • Dormuth, C.R.1    Patrick, A.R.2    Shrank, W.H.3
  • 22
    • 84874812584 scopus 로고    scopus 로고
    • Statins for the primary prevention of cardiovascular disease
    • Taylor F, Huffman M, Macedo A, et al. Statins for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev 2013;1: CD004816.
    • (2013) Cochrane Database Syst Rev , vol.1 , pp. CD004816
    • Taylor, F.1    Huffman, M.2    Macedo, A.3
  • 23
    • 84886631238 scopus 로고    scopus 로고
    • Saturated fat is not the major issue
    • Malhotra A. Saturated fat is not the major issue. BMJ 2013;347:f6340.
    • (2013) BMJ , vol.347 , pp. f6340
    • Malhotra, A.1
  • 25
    • 33846932095 scopus 로고    scopus 로고
    • Factors associated with adherence to drug therapy: A population-based study
    • Bardel A, Wallander M-A, Svärdsudd K. Factors associated with adherence to drug therapy: a population-based study. Eur J Clin Pharmacol 2007;63:307-14.
    • (2007) Eur J Clin Pharmacol , vol.63 , pp. 307-314
    • Bardel, A.1    Wallander, M.-A.2    Svärdsudd, K.3
  • 26
    • 40949131340 scopus 로고    scopus 로고
    • Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease
    • Ho PM, Magid DJ, Shetterly SM, et al. Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease. Am Heart J 2008;155:772-9.
    • (2008) Am Heart J , vol.155 , pp. 772-779
    • Ho, P.M.1    Magid, D.J.2    Shetterly, S.M.3
  • 27
    • 84875727583 scopus 로고    scopus 로고
    • Discontinuation of statins in routine care settings: A cohort study
    • Zhang H, Plutzky J, Skentzos S, et al. Discontinuation of statins in routine care settings: a cohort study. Ann Intern Med 2013;158:526-34.
    • (2013) Ann Intern Med , vol.158 , pp. 526-534
    • Zhang, H.1    Plutzky, J.2    Skentzos, S.3
  • 28
    • 84866371890 scopus 로고    scopus 로고
    • Proportion and risk indicators of nonadherence to statin therapy: A meta-analysis
    • Lemstra M, Blackburn D, Crawley A, et al. Proportion and risk indicators of nonadherence to statin therapy: a meta-analysis. Can J Cardiol 2012;28:574-80.
    • (2012) Can J Cardiol , vol.28 , pp. 574-580
    • Lemstra, M.1    Blackburn, D.2    Crawley, A.3
  • 29
    • 50849088669 scopus 로고    scopus 로고
    • Discontinuation of statin therapy following an acute myocardial infarction: A population-based study
    • Daskalopoulou SS, Delaney JAC, Filion KB, et al. Discontinuation of statin therapy following an acute myocardial infarction: a population-based study. Eur Heart J 2008;29:2083-91.
    • (2008) Eur Heart J , vol.29 , pp. 2083-2091
    • Daskalopoulou, S.S.1    Delaney, J.A.C.2    Filion, K.B.3
  • 30
    • 0038336618 scopus 로고    scopus 로고
    • Discontinuation and switching of therapy after initiation of lipid-lowering drugs: The effects of comorbidities and patient characteristics
    • Yang C-C, Jick SS, Testa MA. Discontinuation and switching of therapy after initiation of lipid-lowering drugs: the effects of comorbidities and patient characteristics. Br J Clin Pharmacol 2003;56:84-91.
    • (2003) Br J Clin Pharmacol , vol.56 , pp. 84-91
    • Yang, C.-C.1    Jick, S.S.2    Testa, M.A.3
  • 31
    • 84908137414 scopus 로고    scopus 로고
    • Re: Adverse effects of statins
    • Fahey T, Smith S. Re: adverse effects of statins. BMJ 2014;348:g3306.
    • (2014) BMJ , vol.348 , pp. g3306
    • Fahey, T.1    Smith, S.2
  • 32
    • 34848852679 scopus 로고    scopus 로고
    • Inequalities in the primary care of patients with coronary heart disease and serious mental health problems: A cross-sectional study
    • Hippisley-Cox J, Parker C, Coupland C, et al. Inequalities in the primary care of patients with coronary heart disease and serious mental health problems: a cross-sectional study. Heart 2007;93:1256-62.
    • (2007) Heart , vol.93 , pp. 1256-1262
    • Hippisley-Cox, J.1    Parker, C.2    Coupland, C.3
  • 33
    • 0035820379 scopus 로고    scopus 로고
    • Sex inequalities in ischaemic heart disease in general practice: Cross sectional survey
    • Hippisley-Cox J, Pringle M, Crown N, et al. Sex inequalities in ischaemic heart disease in general practice: cross sectional survey. BMJ 2001;322:832.
    • (2001) BMJ , vol.322 , pp. 832
    • Hippisley-Cox, J.1    Pringle, M.2    Crown, N.3
  • 34
    • 84926500115 scopus 로고    scopus 로고
    • Initiation rates of statin therapy for the primary prevention of cardiovascular disease: An assessment of differences between countries of the UK and between regions within England
    • O'Keeffe AG, Petersen I, Nazareth I. Initiation rates of statin therapy for the primary prevention of cardiovascular disease: an assessment of differences between countries of the UK and between regions within England. BMJ Open 2015;5:e007207.
    • (2015) BMJ Open , vol.5 , pp. e007207
    • O'Keeffe, A.G.1    Petersen, I.2    Nazareth, I.3
  • 35
    • 77953711938 scopus 로고    scopus 로고
    • Unintended effects of statins in men and women in England and Wales: Population based cohort study using the QResearch database
    • Hippisley-Cox J, Coupland C. Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database. BMJ 2010;340:c2197.
    • (2010) BMJ , vol.340 , pp. c2197
    • Hippisley-Cox, J.1    Coupland, C.2
  • 36
    • 77549087054 scopus 로고    scopus 로고
    • Statins and risk of incident diabetes: A collaborative meta-analysis of randomised statin trials
    • Sattar N, Preiss D, Murray HM, et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet 2010;375:735-42.
    • (2010) Lancet , vol.375 , pp. 735-742
    • Sattar, N.1    Preiss, D.2    Murray, H.M.3
  • 37
    • 0037648948 scopus 로고    scopus 로고
    • Cataract and the use of statins: A case-control study
    • Smeeth L, Hubbard R, Fletcher AE. Cataract and the use of statins: a case-control study. QJM 2003;96:337-43.
    • (2003) QJM , vol.96 , pp. 337-343
    • Smeeth, L.1    Hubbard, R.2    Fletcher, A.E.3
  • 38
    • 84939607655 scopus 로고    scopus 로고
    • Data resource profile: Clinical practice research datalink (CPRD)
    • Herrett E, Gallagher AM, Bhaskaran K, et al. Data resource profile: Clinical Practice Research Datalink (CPRD). Int J Epidemiol 2015;44:827-36.
    • (2015) Int J Epidemiol , vol.44 , pp. 827-836
    • Herrett, E.1    Gallagher, A.M.2    Bhaskaran, K.3
  • 40
    • 0032717032 scopus 로고    scopus 로고
    • The use of fractional polynomials to model continuous risk variables in epidemiology
    • Royston P, Ambler G, Sauerbrei W. The use of fractional polynomials to model continuous risk variables in epidemiology. Int J Epidemiol 1999;28:964-74.
    • (1999) Int J Epidemiol , vol.28 , pp. 964-974
    • Royston, P.1    Ambler, G.2    Sauerbrei, W.3
  • 41
    • 20344370565 scopus 로고    scopus 로고
    • Multiple imputation of missing values
    • Royston P. Multiple imputation of missing values. Stata J 2004;4:227-41.
    • (2004) Stata J , vol.4 , pp. 227-241
    • Royston, P.1
  • 42
    • 34547662843 scopus 로고    scopus 로고
    • Imputation is beneficial for handling missing data in predictive models
    • Steyerberg EW, Van Veen M. Imputation is beneficial for handling missing data in predictive models. J Clin Epidemiol 2007;60:979.
    • (2007) J Clin Epidemiol , vol.60 , pp. 979
    • Steyerberg, E.W.1    Van Veen, M.2
  • 43
    • 84866366696 scopus 로고    scopus 로고
    • Nonadherence to statin therapy: Discontinuation after a single fill
    • Lemstra M, Blackburn D. Nonadherence to statin therapy: discontinuation after a single fill. Can J Cardiol 2012;28:567-73.
    • (2012) Can J Cardiol , vol.28 , pp. 567-573
    • Lemstra, M.1    Blackburn, D.2
  • 44
    • 78650359092 scopus 로고    scopus 로고
    • Impact of a policy allowing for over-the-counter statins
    • Mainous Iii AG, Baker R, Everett CJ, et al. Impact of a policy allowing for over-the-counter statins. Qual Prim Care 2010;18:301-6.
    • (2010) Qual Prim Care , vol.18 , pp. 301-306
    • Mainous, A.G.1    Baker, R.2    Everett, C.J.3
  • 45
    • 35748982438 scopus 로고    scopus 로고
    • Factors related to adherence to statin therapy
    • McGinnis B, Olson K, Magid D, et al. Factors related to adherence to statin therapy. Ann Pharmacother 2007;41:1805-11.
    • (2007) Ann Pharmacother , vol.41 , pp. 1805-1811
    • McGinnis, B.1    Olson, K.2    Magid, D.3


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