Association between childhood exposure to single general anesthesia and neurodevelopment: a systematic review and meta-analysis of cohort study

Journal of Anesthesia

Volumn 29, Issue 5, 2015, Pages 749-757

  Zhang, Haifeng ^a   Du, Lili ^b   Du, Zijing ^a   Jiang, Hao ^a   Han, Dong ^a   Li, Qingfeng ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Anesthesia, general anesthetics; Cohort studies; Infant; Neurodevelopmental; Newborn; Pediatrics

Indexed keywords

ANESTHESIA INDUCTION; ARTICLE; BEHAVIOR DISORDER; CHILD; CHILD DEVELOPMENT; CLINICAL EVALUATION; COCHRANE LIBRARY; COGNITIVE DEFECT; COHORT ANALYSIS; DISEASE ASSOCIATION; EMBASE; GENERAL ANESTHESIA; HIGH RISK PATIENT; HUMAN; LEARNING DISORDER; MEDLINE; NERVOUS SYSTEM DEVELOPMENT; PEDIATRIC ANESTHESIA; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; RISK ASSESSMENT; SYSTEMATIC REVIEW; ADVERSE EFFECTS; META ANALYSIS; NEURODEVELOPMENTAL DISORDERS; PRESCHOOL CHILD; RISK;

ANESTHESIA, GENERAL; CHILD, PRESCHOOL; COHORT STUDIES; HUMANS; NEURODEVELOPMENTAL DISORDERS; RISK;

EID: 84945468931     PISSN: 09138668     EISSN: 14388359     Source Type: Journal    
DOI: 10.1007/s00540-015-2030-z     Document Type: Article

References (29)

1. Sun L. Early childhood general anaesthesia exposure and neurocognitive development. Br J Anaesth. 2010;105:i61–8.
2. Wang C, Slikker W Jr. Strategies and experimental models for evaluating anesthetics: effects on the developing nervous system. Anesth Analg. 2008;106:1643–58.
3. Rappaport B, Mellon RD, Simone A, Woodcock J. Defining safe use of anesthesia in children. N Engl J Med. 2011;364:1387–90.
4. Glass NL, Malviya S. Anesthesia in children—limitations of the data on neurotoxicity. N Engl J Med. 2011;364:1466–7.
5. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009;151:264–9.
6. Ko W-R, Huang J-Y, Chiang Y-C, Nfor ON, Ko P-C, Jan S-R, Lung C-C, Chang H-C, Lin L-Y, Liaw Y-P. Risk of autistic disorder after exposure to general anaesthesia and surgery: a nationwide retrospective matched cohort study. Eur J Anaesthesiol. 2014;31:1–8.
7. Ing CH, DiMaggio CJ, Malacova E, Whitehouse AJ, Hegarty MK, Feng T, Brady JE, von Ungern-Sternberg BS, Davidson AJ, Wall MM. Comparative analysis of outcome measures used in examining neurodevelopmental effects of early childhood anesthesia exposure. Anesthesiology. 2014;120:1319–32.
8. Bong CL, Allen JC, Kim JTS. The effects of exposure to general anesthesia in infancy on academic performance at age 12. Anesth Analg. 2013;117:1419–28.
9. Sprung J, Flick RP, Katusic SK, Colligan RC, Barbaresi WJ, Bojanić K, Welch TL, Olson MD, Hanson AC, Schroeder DR. Attention-deficit/hyperactivity disorder after early exposure to procedures requiring general anesthesia. Mayo Clin Proc. 2012;87:120–9.
10. Ing C, DiMaggio C, Whitehouse A, Hegarty MK, Brady J, von Ungern-Sternberg BS, Davidson A, Wood AJ, Li G, Sun LS. Long-term differences in language and cognitive function after childhood exposure to anesthesia. Pediatrics. 2012;130:e476–85.
11. Hansen TG, Pedersen JK, Henneberg SW, Pedersen DA, Murray JC, Morton NS, Christensen K. Academic performance in adolescence after inguinal hernia repair in infancy: a nationwide cohort study. Anesthesiology. 2011;114:1076–85.
12. Flick RP, Katusic SK, Colligan RC, Wilder RT, Voigt RG, Olson MD, Sprung J, Weaver AL, Schroeder DR, Warner DO. Cognitive and behavioral outcomes after early exposure to anesthesia and surgery. Pediatrics. 2011;128:e1053–61.
13. DiMaggio C, Sun L, Li G. Early childhood exposure to anesthesia and risk of developmental and behavioral disorders in a sibling birth cohort. Anesth Analg. 2011;113:1143.
14. Wilder RT, Flick RP, Sprung J, Katusic SK, Barbaresi WJ, Mickelson C, Gleich SJ, Schroeder DR, Weaver AL, Warner DO. Early exposure to anesthesia and learning disabilities in a population-based birth cohort. Anesthesiology. 2009;110:796.
15. Kalkman CJ, Peelen L, Moons KG, Veenhuizen M, Bruens M, Sinnema G, de Jong TP. Behavior and development in children and age at the time of first anesthetic exposure. Anesthesiology. 2009;110:805–12.
16. DiMaggio C, Sun LS, Kakavouli A, Byrne MW, Li G. A retrospective cohort study of the association of anesthesia and hernia repair surgery with behavioral and developmental disorders in young children. J Neurosurg Anesthesiol. 2009;21:286.
17. Bartels M, Althoff RR, Boomsma DI. Anesthesia and cognitive performance in children: no evidence for a causal relationship. Twin Res Hum Genet. 2009;12:246–53.
18. DiMaggio CJ, Sun L, Kakavouli A, Li G. Exposure to anesthesia and the risk of developmental and behavioral disorders in young children. Anesthesiology. 2008;109:A1415.
19. Higgins J, Green SE. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration 2011. Available from: http://www.cochrane-handbook.org.
20. Higgins J, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557–60.
21. Higgins J, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539–58.
22. Berlin JA, Longnecker MP, Greenland S. Meta-analysis of epidemiologic dose-response data. Epidemiology. 1993;4:218–28.
23. Greenland S, Longnecker MP. Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. Am J Epidemol. 1992;135:1301–9.
24. DiMaggio C, Sun LS, Ing C, Li G. Pediatric anesthesia and neurodevelopmental impairments: a Bayesian meta-analysis. J Neurosurg Anesthesiol. 2012;24:376.
25. Sun LS, Li G, DiMaggio CJ, Byrne MW, Ing C, Miller TL, Bellinger DC, Han S, McGowan FX. Feasibility and pilot study of the Pediatric Anesthesia NeuroDevelopment Assessment (PANDA) project. J Neurosurg Anesthesiol. 2012;24:382.
26. Davidson AJ, McCann ME, Morton NS, Myles PS. Anesthesia and outcome after neonatal surgery: the role for randomized trials. Anesthesiology. 2008;109:941–4.
27. Hansen TG, Henneberg SW, Morton NS, Christensen K, Davidson AJ, Lee KJ, Hardy P, Wolf A. Pro–con debate: cohort studies vs the randomized clinical trial methodology in pediatric anesthesia. Paediatr Anaesth. 2010;20:880–94.
28. Cans C. Neonatal exposure to anesthesia and adverse cognitive outcome in childhood. Insight from epidemiology. Archives de pediatrie: organe officiel de la Societe francaise de pediatrie. 2013;20:1011–5.
29. Servick K. Biomedical Research. Researchers struggle to gauge risks of childhood anesthesia. Science (New York, NY). 2014;346(6214):1161–2.