Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis

Circulation Research

Volumn 117, Issue 10, 2015, Pages 835-845

  Ye, Yu Xiang ^a   Calcagno, Claudia ^a   Binderup, Tina ^b   Courties, Gabriel ^b   Keliher, Edmund J ^a   Wojtkiewicz, Gregory R ^a   Iwamoto, Yoshiko ^a   Tang, Jun ^b   Pérez Medina, Carlos ^b   Mani, Venkatesh ^b   Ishino, Seigo ^c   Johnbeck, Camilla Bardram ^c   Knigge, Ulrich ^c   Fayad, Zahi A ^d   Libby, Peter ^d   Weissleder, Ralph ^a   Tawakol, Ahmed ^e   Dubey, Shipra ^e   Belanger, Anthony P ^e   Di Carli, Marcelo F ^f   Swirski, Filip K ^a   Kjaer, Andreas ^g   Mulder, Willem J M ^f   Nahrendorf, Matthias ^a,h   more..

^a Center for Systems Biology   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d PET and Cluster for Molecular Imaging ^*  (United States)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

^h ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

18F fluorothymidine; atherosclerosis; imaging; inflammation; macrophage; positron emission tomography; proliferation

Indexed keywords

3' FLUOROTHYMIDINE F 18; APOLIPOPROTEIN E; BIOLOGICAL MARKER; FLUORODEOXYGLUCOSE F 18; FLUOROURACIL; TOLL LIKE RECEPTOR 4; 2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; 3' FLUOROTHYMIDINE; CHOLESTEROL INTAKE; RADIOPHARMACEUTICAL AGENT;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTICLE; ATHEROGENIC DIET; ATHEROSCLEROTIC PLAQUE; AUTORADIOGRAPHY; BONE MARROW; CARDIOVASCULAR RISK; CAROTID ARTERY; CAROTID ATHEROSCLEROSIS; CELL CYCLE M PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHOLESTEROL DIET; CLINICAL ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; EX VIVO STUDY; EXPERIMENTAL RABBIT; FEMALE; FLOW CYTOMETRY; FRAMINGHAM RISK SCORE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; IN VITRO STUDY; MACROPHAGE; MALE; MOLECULAR IMAGING; MOUSE; NONHUMAN; PET-CT SCANNER; PLASMA HALF LIFE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPLEEN; THREE DIMENSIONAL IMAGING; ANIMAL; AORTIC DISEASES; ATHEROSCLEROSIS; C57BL MOUSE; CAROTID ARTERY DISEASES; CHOLESTEROL INTAKE; DEFICIENCY; DIAGNOSTIC IMAGING; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; LIPID DIET; METABOLISM; MULTIMODAL IMAGING; POSITRON EMISSION TOMOGRAPHY; PREDICTIVE VALUE; RABBIT; RETROSPECTIVE STUDY; THORACIC AORTA; TIME FACTOR; X-RAY COMPUTED TOMOGRAPHY;

ANIMALS; AORTA, THORACIC; AORTIC DISEASES; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BONE MARROW; CAROTID ARTERY DISEASES; CELL PROLIFERATION; CHOLESTEROL, DIETARY; DIDEOXYNUCLEOSIDES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; FEMALE; FLUORODEOXYGLUCOSE F18; HEMATOPOIETIC STEM CELLS; HUMANS; MACROPHAGES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIMODAL IMAGING; PLAQUE, ATHEROSCLEROTIC; POSITRON-EMISSION TOMOGRAPHY; PREDICTIVE VALUE OF TESTS; RABBITS; RADIOPHARMACEUTICALS; RETROSPECTIVE STUDIES; SPLEEN; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84945446887     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.307024     Document Type: Article

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